Dear Reader: Innovations across the entire package - Pharma ...
Dear Reader: Innovations across the entire package - Pharma ...
Dear Reader: Innovations across the entire package - Pharma ...
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Excipients & Actives for <strong>Pharma</strong><br />
No. 26, 2011<br />
The hard work paid off: years of research and<br />
analysis have culminated in BASF’s new proprietary<br />
aluminum-free PeroXeal packaging concept.<br />
The innovative foil comprises three distinct functional<br />
layers, each specifically designed to shield<br />
<strong>the</strong> product from environmental influences. Complemented<br />
by inert gas flushing and heat sealing,<br />
<strong>the</strong> packaging significantly reduces peroxide<br />
levels and eliminates <strong>the</strong> risk of contamination<br />
with aluminum flakes – at no additional cost to<br />
<strong>the</strong> customer.<br />
The PeroXeal edge has allowed BASF to raise<br />
<strong>the</strong> bar even fur<strong>the</strong>r in <strong>the</strong> PVP market. By preventing<br />
degradation of <strong>the</strong> excipients’ superior<br />
quality and incredible freshness, <strong>the</strong> packaging<br />
concept has increased Kollidon’s shelf life to<br />
four years. So worrying about peroxide levels, K<br />
values and API degradation is a thing of <strong>the</strong> past.<br />
FIGURE 2<br />
No degradation of K value<br />
(Usual decrease of K value in contact with air is around<br />
0.2 units per month)<br />
k-value<br />
94<br />
92<br />
Kollidon 90F in<br />
90<br />
88<br />
standard BASF<br />
packaging<br />
86<br />
84<br />
82<br />
Povidone K90 in<br />
standard market<br />
packaging<br />
80<br />
0 1 3 6 9 12 18 24 36 48<br />
Comparison of K values<br />
Months<br />
Kollidon 90F<br />
in new BASF<br />
packaging<br />
The groundbreaking<br />
PeroXeal packaging<br />
concept now marks <strong>the</strong><br />
next stage in <strong>the</strong> evolution<br />
of Kollidon.<br />
FIGURE 3<br />
Transparent aluminum-free packaging avoids product contamination with aluminum flakes<br />
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