SEE INSIDE - Pittsburgh Tissue Engineering Initiative

YOUR INVITATION TO ATTEND THIS INCOMPARABLE INTERNATIONAL EVENT! 

In conjunction with the Society For Biomaterials (SFB) Annual Meeting 

SHARE IN THIS POWERFUL VISION 

SEE INSIDE Exceptional programming for you! 

Featured Keynote Presenters 

Pre-Congress Tutorials 

Scientific Sessions following a Comprehensive List of Topic Tracks 

Expo and Poster Session 

Special Focus on Student Programming 

Joint REGENERATE/SFB Networking and SFB Congress Overlap 

SELL-OUT CROWD EXPECTED! Register today at www.regenerate-online.com or call 412-235-5116

AN INVITATION FROM THE WORLD CONGRESS CHAIRS 

2006 WORLD CONGRESS 

SCIENTIFIC ADVISORY COMMITTEE 

2 

Welcome to REGENERATE WORLD CONGRESS 2006 

Alan J. Russell, PhD 

Chairman 

McGowan Institute for 

Regenerative Medicine 

On behalf of the Tissue Engineering and Regenerative Medicine International 

Society (TERMIS) and the Pittsburgh Tissue Engineering Initiative (PTEI) it is our 

sincere pleasure to invite you to attend this premiere event. Together with the 

support of Wake Forest Institute for Regenerative Medicine and the National 

Regenerative Medicine Foundation, we will be hosting over 500 combined 

scientific presentations, 700 attendees, 30 exhibitors, and 200 students and 

faculty at this international meeting. For the first time, we are co-locating with 

the Society For Biomaterials (SFB)to further advance the research, 

development of and dissemination of the latest findings critical to regenerative 

medicine and its enabling technologies. 

In today's global economy, few areas receive as much attention from both 

scientific and lay press due to the field's future promise. Imagine that within our 

lifetime, the T.E. community will be integral in developing technologies that will 

alleviate painful procedures and enable significant tissue repair procedures -- 

both dramatically enhancing the patient's quality of life. We invite you to share in 

this powerful vision with us as we host 2000+ in Pittsburgh, Pennsylvania, April 

25-27, 2006. 

As organizers, we guarantee that by attending the REGENERATE WORLD 

CONGRESS, you will have the opportunity to get the most comprehensive update 

on global issues affecting the industry, the latest information about regulatory 

changes, and preview the most promising technological innovations as scientific 

sessions selected by our respected review team. 

Our goal is to provide the attendee with a quality education, access to a global 

network of scientific concepts, theories and collaborations, first-hand exposure 

to innovative tools, products & services through a first-class exhibition program 

and the opportunity to network with your peers. 

In addition to the general program portion of the overall conference, we are 

proud to include a hands-on educational workshop for student attendees, along 

with networking and social activities tailored with the student in mind. 

We look forward to hosting you in April. 

Alan Russell, PhD 

William R. Wagner, PhD 

Scientific Chairman 

McGowan Institute for 

Regenerative Medicine 

William Wagner, PhD 

P.S. We extend our sincere thanks to the many individuals submitting abstracts this 

year. The numbers surpassed our highest expectations and we truly appreciate your 

interest in participating in this outstanding program. 

Alan J. Russell, PhD - Chairman 

McGowan Institute for Regenerative Medicine 

William R. Wagner, PhD - Scientific Chairman 


Anthony Atala, MD 

Wake Forest Institute for Regenerative Medicine 

Augustinus Bader, MD, PhD 

University of Leipzig 

Stephen Francis Badylak, DVM, MD, PhD 


Karen J. L. Burg, PhD 

Clemson University 

Arnold I. Caplan, PhD 

Case Western Reserve University 

Alan Colman, PhD 

ES Cell International 

Ulrich Dirnagl, PhD 

Charite Hospital, Humboldt University 

Andres J. Garcia, PhD 

Georgia Institute of Technology 

Jörg C. Gerlach, MD, PhD 


David Grainger, PhD 

Colorado State University 

Robert E. Guldberg, PhD 


Timothy E. Hardingham, PhD, DSc 

University of Manchester 

Kiki B. Hellman, PhD 

The Hellman Group, LLC 

Jons Hilborn, PhD 

Uppsala University 

Peter C. Johnson, MD 

Scintellix, LLC 

Weiyuan John Kao, PhD 

University of Wisconsin-Madison 

Haibang Lee, PhD 

Korea Research Institute of Chemical Technology (KRICT) 

Wei Liu, MD, PhD 

Shanghai Second Medical University, PRC 

Michael Lysaght, PhD 

Brown University 

Ronald McKay, PhD 

NIH Neurological Institute 

Robert M. Nerem, PhD 


Hideyuki Okano, MD, PhD 

Keio University, School of Medicine 

Buddy D. Ratner, PhD 

University of Washington 

Rui L. Reis, PhD 

University of Minho, Portugal 

Shelly E. Sakiyama-Elbert, PhD 

Washington University 

Michael V. Sefton, PhD 

University of Toronto 

Kevin Shakesheff, PhD 

University of Nottingham 

David Smith, JD 

Teregenics, LLC 

David F. Williams, PhD 

UK Centre for Tissue Engineering 

Masayuki Yamato, PhD 

Tokyo Women's Medical University 

TABLE OF CONTENTS 

Organizing and Hosting Organizations..............................1 

Welcome to Regenerate World Congress 2006 ................2 

Scientific Advisory Committee .........................................2 

Pre-Congress Tutorials.....................................................3 

Featured Keynote Speakers .............................................3 

SFB Collaborative Sessions .............................................3 

Regenerate World Congress Program Agenda..............4-7 

Exhibitors and Sponsors............................................8-10 

Student Activities ..........................................................10 

Registration and Accommodations Information.............11 

Registration Form..........................................................12

SPECIAL EVENTS AND PROGRAM HIGHLIGHTS 

Monday, April 24 

Pre-Conference Tutorials - 

Clinical Translation 

A good clinical trial design begins with 

an appropriate study and a strong 

implementation plan. This session will 

develop and apply the theory of clinical 

trial design and analysis, discuss the 

practical issues of financing and 

implementing clinical trials, and other 

issues such as: 

Clinical Need and End-Users 

Selection/Assessment of Outcome 

Criteria 

Selection of Patient Populations 

and Health Care Costs 

Sites for Clinical Trials: Global 

Paradigm and Financing 

AGENDA 

1:00 – 1:15 pm 

Introduction 

Kiki Hellman, PhD, The Hellman Group 

LLC 

1:15 – 2:00 pm 

Clinical Need and End Users 

Mathew Pollman, MD, Guidant 

2:00 – 2:45 pm 

Selection/Assessment of Outcome 

Criteria 

Frederick Schoen, MD, PhD, Harvard 

Medical School 

2:45 – 3:00 pm 

Refreshment Break 

3:00 – 3:45 pm 

Selection of Patient Populations and 

Health Care Costs 

Kim Norton, Certus Healthcare 

Consulting, LLC 

3:45 – 4:30 pm 

Sites for Clinical Trials: Global 

Paradigm and Financing 

Thomas Eggerman, MD, National 

Institutes of Health 

4:30 – 5:00 pm 

Discussion 

For special Student Activities, 

please see page 10. 

Keynote Presenters 

Tuesday, April 25 

Dr. Gregory Stock is the Director of the Program on Medicine, 

Technology and Society at UCLA's School of Medicine. In this role 

he explores critical technologies poised to have large impacts on 

humanity's future and the shape of medical science. His goal 

has been to bring about a broad public debate on these 

technologies and their implications, leading to wise public 

policies surrounding their realization. A symposium Dr. Stock 

convened a few years ago on the possibilities of manipulating 

the genetics of human embryos drew international attention as 

the first major public discussion of this issue among 

distinguished scientists and opened a global debate on this 

hitherto taboo topic. 

Wednesday, April 26 

J.J. Collins of the Center for BioDynamics and the Department 

of Biomedical Engineering, Boston University is the Keynote 

Speaker during the joint Ceremony/Bash with the SFB Annual 

Meeting. As a leader in the field of systems biology, J.J. Collins 

offers a unique perspective to understand the important 

interrelationships between the worlds of materials and biology. 

Dr. Collins' research focuses on developing nonlinear dynamical 

techniques and devices to characterize, improve and mimic 

biological function. 

BioBlast Meets Regenerate 

Dr. J.J. Collins opens the joint World Congress/SFB Annual Meeting sessions with 

BioBlast on Wednesday, April 26. BioBlast is a quarterly gathering of the Southwestern 

Pennsylvania regional life sciences community. This event is held in conjunction with 

the 2006 Regenerate World Congress and the 2006 Society For Biomaterials Annual 

Meeting. BioBlast brings together scientists – who are creating the innovations that 

eventually will prolong and save lives – with venture capitalists, entrepreneurs, 

lawyers, and service providers. Events are casual, with plentiful food and drink, 

focused around a short speech by a leading member of the life sciences community 

or a guest from out of town. The goal of BioBlast is to serve as a networking venue for 

the nascent life sciences community as well as to encourage commercialization of 

new technologies and entrepreneurial mentoring. 

BioBlast is sponsored by Kirkpatrick & Lockhart Nicholson Graham LLP and is hosted 

by LaunchCyte, University of Pittsburgh Office of Enterprise Development, the 

Pittsburgh Life Sciences Greenhouse, and the Pittsburgh Technology Council. 

Thursday, April 27 

Collaborative Sessions with the 

Society For Biomaterials Annual Meeting 

On Thursday, April 27, 2006, scientific sessions are held concurrently with the Society 

For Biomaterials Annual Meeting. Because of the collaboration between PTEI, TERMIS 

and SFB, joint programming is offered to both the World Congress and the SFB Annual 

Meeting attendees. For more information, or to register for the entire Society For 

Biomaterials Annual Meeting, please visit www.biomaterials.org/Meetings/ 

06AnnualMeeting/. To obtain more information on the combined discounted 

Regenerate/SFB registration fees, please contact PTEI at 412-235-5116. 

3 


Preliminary Program – For full details of the Scientific Sessions check: www.regenerate-online.com 

MONDAY - APRIL 24 

9:00 a.m. 

1:00 pm – 

4:00 pm 

Registration Open (Westin Hotel) 

Pre-Congress Tutorials 

CLINICAL TRANSLATION 

A good clinical trial design begins with an appropriate study and a strong implementation plan. This session will develop and apply the theory of 

clinical trial design and analysis, discuss the practical issues of financing and implementing clinical trials, and other issues such as: 

clinical need and the therapy’s niche in patient care; 

considerations of the clinician/surgeon, i.e., the end-user; 

selection of patient population(s) and sites for clinical trials; selection and assessment of the therapeutic outcome criteria 

Presenters Include: 

Kiki Hellman, PhD, The Hellman Group LLC; Mathew Pollman, MD, Guidant; Frederick Schoen, MD, PhD, Harvard Medical School; Kim Norton, 

Certus Healthcare Consulting, LLC; Thomas Eggerman, MD, National Institutes of Health 

4 

TUESDAY - APRIL 25 

8:30 a.m. 

TRACK 

TRACK 

CHAIR 

Opening Keynote - Gregory Stock, PhD, MBA, UCLA School of Medicine 

Cardiovascular I Orthopedic I Cancer & Regenerative Medicine Soft Tissue Repair I 

Robert Nerem, PhD 




Robert Guldberg, PhD 


Peter Johnson, MD 

Scintellix, LLC 

Alan Colman, PhD 

ES Cell International 

Nick Rhodes, PhD 

University of Liverpool 

TRACK 

DESCRIPTION 

Cardiovascular sessions broadly focus on 

regenerative medicine approaches to 

cardiovascular disease, including tissue 

engineering, cell therapies, and devices. 

Regenerating or replacing connective 

tissues that serve a significant 

biomechanical function has proven 

exceptionally challenging. These 

sessions provide an update on the 

latest advances towards restoring 

function to both hard and soft 

musculoskeletal tissues damaged due 

to injury or disease. 

Cancer and regenerative medicine share a 

common basis in technology, including 

manipulation of growth factor, cell attachment 

and differentiation pathways. Cell 

therapies, including stem cell therapies are 

becoming more important in cancer therapy 

and are critical to regenerative medicine. 

In this session, such convergent technolo - 

gies are discussed and opportunities for 

communion between investigators in these 

two fields is highlighted. 

These sessions will highlight some 

recent studies demonstrating current 

approaches and issues involved in the 

repair and regeneration of soft tissues 

and present current thinking regarding 

the engineering and construction of 

cell-seeded and acellular scaffolds. 

TRACK 

TRACK 

CHAIR 

Cardiovascular II Orthopedic II Metabolic Tissue Engineering Soft Tissue Repair II 





Rui Reis, CEng. MSc, PhD 

University of Minho, Portugal 

Michael Lysaght, PhD 

Brown University 

Nick Rhodes, PhD 

University of Liverpool 

TRACK 

DESCRIPTION 

Cardiovascular sessions broadly focus 

on regenerative medicine approaches to 

cardiovascular disease, including tissue 

engineering, cell therapies, and devices. 


tissues that serve a significant 

biomechanical function has proven 

exceptionally challenging. These 

sessions provide an update on the 

latest advances towards restoring 

function to both hard and soft 

musculoskeletal tissues damaged due 

to injury or disease. 

Deterioration of major internal organs represents 

one of the most persistently refractory 

problems facing modern medicine and 

one of the great impact-opportunities for 

cell-based medical therapies. The biohybrid 

kidney is now in very promising phase II/III 

clinical trials; the cell-based liver has 

achieved clinical success if not regulatory 

approval; the bioartificial pancreas has 

long since demonstrated efficacy in rodent 

models but not advanced beyond this 

point. This session explores the current 

status of these approaches as well as the 

application of their underlying technology 

to other forms of therapeutic intervention. 

These sessions will highlight some 

recent studies demonstrating current 

approaches and issues involved in 

the repair and regeneration of soft 

tissues and present current thinking 

regarding the engineering and 

construction of cell-seeded and 

acellular scaffolds.

TRACK 

TRACK 

CHAIR 

Cardiovascular III Orthopedic III Neural I Facts and Theories of 

Organ Regeneration 





Aaron Goldstein, PhD 

Virginia Polytechnic Institute and State University 

Gilson Khang, PhD 

Chonbuk National University 

Shelly Sakiyama-Elbert, PhD 




Ioannis Yannas, PhD 

Massachusetts Institute of Technology 

TRACK 

DESCRIPTION 


regenerative medicine approaches to cardiovascular 

disease, including tissue engineering, 

cell therapies, and devices. 


tissues that serve a significant biomechanical 

function has proven exception - 

ally challenging. These sessions provide 

an update on the latest advances 

towards restoring function to both hard 

and soft musculoskeletal tissues damaged 

due to injury or disease. 

In these sessions, broad topics on the 

regeneration of nervous system are cov - 

ered including the basic biology of neural 

stem cells in fetal and adult stages, axonal 

regeneration, tissue engineering and cell 

therapies for damaged brain and spinal 

cord, PNS and CNS regeneration and neu - 

ral crest cells. Half of the speakers are 

invited and the remaining half of them are 

from submitted abstracts. 

The session on Facts and Theories of 

Organ Regeneration focuses on the 

emerging theoretical underpinnings of 

regenerative medicine. Theories of the 

transition from early fetal to late fetal 

healing are contrasted with those culled 

from the practice of organ regeneration 

in adults. The material presented in this 

session should be helpful in developing 

sound strategies for inducing organ 

regeneration in adult mammals. 

TRACK 

Cardiovascular IV Oral/Dental/Craniofacial Neural II Skin/Wound Healing 

TRACK 

CHAIR 





Jeremy Mao, DDS, PhD 

University of Illionois at Chicago 

Pamela Yelick, PhD 

The Forsyth Institute 

Shelly Sakiyama-Elbert, PhD 




Adam Katz, MD 

University of Virginia Health System 

TRACK 

DESCRIPTION 


regenerative medicine approaches to car - 

diovascular disease, including tissue engineering, 

cell therapies, and devices. 

The field of tissue engineering for dental 

and craniofacial applications is rapidly 

evolving. Success in this effort is 

dependent on advances in biomaterials 

fabrication and design, progenitor cell 

characterization, and localized gene and 

protein delivery techniques. This session 

includes presentations of some state of 

the art techniques currently being developed 

for the repair and regeneration of 

dental and orofacial tissues. 

In these sessions, broad topics on the 

regeneration of nervous system are cov - 

ered including the basic biology of neural 

stem cells in fetal and adult stages, axonal 

regeneration, tissue engineering and cell 

therapies for damaged brain and spinal 

cord, PNS and CNS regeneration and neural 

crest cells. Half of the speakers are 

invited and the remaining half of them are 

from submitted abstracts. 

Complicated wounds and chronic skin 

ulcers remain a significant clinical challenge 

despite concerted efforts toward 

their prevention and treatment. This 

session highlights emerging ideas and 

innovative strategies aimed to address 

challenges of impaired healing, chronic 

wounds and skin/soft tissue reconstruction/regeneration. 

5 

WEDNESDAY - APRIL 26 

8:30 a.m. 

TRACK 

TRACK 

CHAIR 

Panel - Tissue Engineering Centers from around the World: An Overview 

Organizer: Michael Lysaght, PhD and Robert Nerem, PhD 

Cell Sourcing I Linking Pre-Clinical & Clinical Studies Cell Targeting 

Nancy Dock, PhD 

Cambrex Bio Science 

David Williams, PhD 

UK Centre for Tissue Engineering 

Kevin Shakesheff, PhD 

University of Nottingham 

TRACK 

DESCRIPTION 

Presentations will include novel models for cell 

manipulation including mechanical stimulation 

and transfection. Chemical means to induce differentiation 

and de-differentiation will be discussed. 

Optimization of methods for isolation and induction 

of cells for research and clinical application 

will be presented. 

After some 15 to 20 years of experimental work, and 10 

years of very limited clinical experiences, the field of 

regenerative medicine is just now gearing up to translate 

the experiences so far gained into major clinical studies 

and trials. However, the regulatory environment has not 

been sufficiently well developed to allow for this to be 

achieved with confidence. The nature of the essential 

pre-clinical studies that should be required for approval 

to start clinical trials has not been determined. This session 

will address the interface between pre-clinical and 

clinical studies. 

A major barrier to successful clinical implementation of 

regenerative medicine is the challenge of delivering cells 

and other therapeutic agents to the precise site of tissue 

repair. Accurate delivery of cells within the body requires 

new approaches to the development of injectable biomaterials 

that can protect cells, provide the initial regenerative 

environment, promote angiogenesis and withstand 

mechanical forces exerted by surrounding tissues. Matrixassisted 

cell delivery is making a clinical impact in a number 

of applications and the need for more complex delivery 

systems for stem cells for use in the brain, nervous system, 

liver, heart and many other tissues is driving the academic 

and commercial development of this area. 


Preliminary Program – For full details of the Scientific Sessions check: www.regenerate-online.com 

WEDNESDAY - APRIL 26 continued 

TRACK 

TRACK 

CHAIR 

Cell Sourcing II 

Johnny Huard, PhD 


Tissue Engineering & Regenerative 

Medicine in the Clinic (Part 1) 

Stephen Badylak, DVM, MD, PhD 


Cell Tracking 

Dan Gazit, PhD, DMD 

The Hebrew University of Jerusalem 

6 

TRACK 

DESCRIPTION 

TRACK 

Presentations will include novel models for 

cell manipulation including mechanical 

stimulation and transfection. Chemical means 

to induce differentiation and de-differentiation 

will be discussed. Optimization of methods for 

isolation and induction of cells for research 

and clinical application will be presented. 

Embryonic Stem Cells I 

The subject matter of this session focuses upon the 

clinical translation of regenerative medicine concepts 

from the benchtop to the bedside and patient care. The 

talks cover aspects of regulatory requirements, academicindustry 

collaborations, third party reimbursement issues, 

and important clinical considerations for moving 

regenerative medicine into the clinic. 

Tissue Engineering & Regenerative 

Medicine in the Clinic (Part 2) 

Cell tracking could be a crucial issue in cell therapy and tissue 

engineering. Either in a systemic or local approach of cell 

implantation, tracking and monitoring the therapeutic cells is 

mandatory in order to determine: 

•Cell survival 

•Biodistribution 

•Cell function in tissue/organ repair (i.e. stem cell 

differentiation). 

•Cell homing and engraftment. 

Conventional methods of cell tracking included invasive methods 

that required the sacrifice of the experimental model avoiding 

the possibility of longitudinal, real-time monitoring of cells in vivo. 

Current, state-of-the-art technologies utilize genetic engineering, 

bioluminescence, fluorescence, nanotechnology and intra vital 

microscopy in order to provide non invasive, quantitative and longitudinal 

tracking of cells in vivo. There is no doubt that by better 

means of cell tracking in vivo, the field of tissue engineering 

would be able to better understand regeneration processes and 

to optimize cell-based approaches for tissue repair. 

Advances in Cell Culture Media 

TRACK 

CHAIR 

Todd McDevitt, PhD 

Georgia Institute of Technology and Emory University 

Dong-Wook Kim, PhD 

Yonsei University College of Medicine 

Stephen Badylak, DVM, MD, PhD 


David Grainger, PhD 

Colorado State University 

TRACK 

DESCRIPTION 

Embryonic stem (ES) cells may serve as a 

pluripotent cell source for the treatment of a 

number of degenerative cellular diseases. This 

session will highlight recent advances in the 

derivation, cultivation and differentiation 

methods for ES cells, as well as the 

development of novel therapeutic applications 

of ES cells and stem cell-derived products. 

The subject matter of this session focuses upon the 

clinical translation of regenerative medicine concepts 

from the benchtop to the bedside and patient care. The 

talks cover aspects of regulatory requirements, academicindustry 

collaborations, third party reimbursement issues, 

and important clinical considerations for moving 

regenerative medicine into the clinic. 

Various deliberate and inadvertent cell culture conditions are 

becoming increasingly recognized for important influences 

on cells in culture. Different media, different serum sources, 

serum-free additives, and specific growth factors and hormones 

are soluble variables; hydrodynamic shear, oscillatory 

changes, and other fluid stimuli are another source of vari - 

ables. Full appreciation of these conditions is important to 

control cell phenotypic stability and regenerative destiny in 

cultures and bioreactors. This session provides a forum for 

presenting and discussing the latest thinking regarding such 

influences on secondary, primary and stem cell lineages. 

TRACK 

Cell-Based Sensing 

Pre-clinical Studies and Clinical Success: 

Guiding Principles (Panel Session) 

Cell Integration into Natural & Synthetic Matrices 

TRACK 

CHAIR 

William Reichert, PhD 

Duke University 

Anne Plant, PhD 

National Institute of Standards and Technology 

Kiki Hellman, PhD 

The Hellman Group LLC 

Arnold Caplan, PhD 

Case Western Reserve 

TRACK 

DESCRIPTION 

This session on cell-based biosensors examines 

analytical systems that employ or take 

advantage of detection and transduction 

schemes intrinsic to native cells or engineered 

into cells modified for analytical purposes. 

Particular interest is placed on 

approaches that are implementable in a high 

throughput format or that are amenable to 

combinatorial assay. 

The panel focuses on discussions and development of 

generic considerations for pre-clinical and clinical studies 

that lead to a successful therapy. Special attention is 

given to preclinical studies as key determinants for 

clinical success with focus on: clinical trial design; 

selection of patient profiles, i.e., inclusion/exclusion 

criteria; and determination of safety and effectiveness 

criteria and assessment measures. 

The principles of tissue formation and properties of 

natural materials can be merged to provide composite 

constructs used for tissue engineered regeneration of 

various tissues. Key issues addressed involve the use of 

the appropriate cells, in the proper numbers and in the 

optimal formulation of natural materials to organize 

tissue engineered regeneration. 

BioBlast - J.J. Collins, MD, Center for BioDynamics and the Development of Biomedical Engineering, Boston University

THURSDAY - APRIL 27 

8:30 a.m. 

Panel - Third Party Reimbursement 

Organizer: David Smith, JD; Kiki Hellman, PhD 

TRACK 

TRACK 

CHAIR 

TRACK 

DESCRIPTION 

TRACK 

TRACK 

CHAIR 

TRACK 

DESCRIPTION 

TRACK 

TRACK 

CHAIR 

Biomechanical Training of Tissue Constructs 

David Vorp, PhD 

McGowan Institute for Regnerative Medicine 

It has been shown that biomechanical stimulation aids 

the development and remodeling of tissue engineered 

constructs. This session provides the latest advances in 

this area, including bioreactor design and 

implementation. 

Bioreactors 

Jörg Gerlach, MD, PhD 


The focus is on technologies for 3-D liver cell and 

hepatic progenitor in vitro culture and systems for cell 

based therapy development in regenerative medicine. 

Structural and Biomechanical 

Characterization: Synthetic Scaffolds 

Michael Sacks, PhD 


Digitally Enabled Tissue Engineering 

Thomas Boland, PhD 


Recent progress in CAD/CAM, biomaterials and 3D 

fabrication technology, has resulted in a new generation of 

hybrid materials. These hybrid materials are built 

according to engineering design principles to enhance the 

function of engineered tissues and hold much promise in 

the area of regenerative medicine. This session focuses on 

recent advances in this area, including CAD/CAM design of 

scaffolds with optimized porosities, advances in 3D protein 

and cell patterning, process modeling, and experimental 

studies of designer hybrid materials. 

Extensions of Regenerative Medicine to 

Ex Vivo Discovery 

Karen Burg, PhD 


Linda Griffith, PhD 

Biotechnology Process Engineering Center, MIT 

The early concept of developing tissue for reconstructive 

purposes has evolved to include the construction of test 

tissues systems for therapeutic development, 

developmental cell biology studies, and disease 

prevention. This session includes all aspects of tissue test 

system construction and application 

Addressing Immune System Issues 

Julia Babensee, PhD 


Society For Biomaterials 

Annual Meeting 

General Sessions 

Biomimesis in Drug Delivery I: 

Scaffolds & Implants 

Cell Response to Micro/nanopatterned 

Biomaterials I 

Stem Cells: Source, Culture and 

Application Symposium I 

Urological Tissue Engineering and 

Biomaterials 

Biodegradable Hydrogels for Tissue 

Engineering I 

Bionanotechnology: the Future of 

Biomaterials Symposium I 

New Concepts and Challenges for the 

Delivery of Therapeutic Nucleic Acids 

Symposium 

Organic/Inorganic Hybrid Biomaterials 

Symposium I 

7 

TRACK 

DESCRIPTION 

TRACK 

TRACK 

CHAIR 

TRACK 

DESCRIPTION 

Structural and biomechanical characterization of 

synthetic and natural biomaterials will be presented. 

Structural and Biomechanical 

Characterization: Biological Scaffolds 

Michael Sacks, PhD 


Structural and biomechanical characterization of 

synthetic and natural biomaterials will be presented. 

This session examines host response issues in 

regenerative medicine. Topics include; innate immune 

responses to biomaterials, tissue engineered constructs 

and effects on transplanted cells and regeneration, 

allograft and xenograft rejection, immune responses to 

stem cells, and strategies for controlling innate and 

adaptive immune responses in regenerative medicine. 

Controlled Ligand Presentation 

Andres Garcia, PhD 


Bio-inspired strategies to present bioactive ligands, such as 

adhesion motifs and growth/differentiation factors, have 

emerged as promising approaches to elicit desired healing 

responses in several tissues. This session focuses on novel 

strategies to attain controlled ligand presentation, 

highlighting recent successes, challenges and 

opportunities. 

Surface Modification and 

Characterization of Biomaterials I 

The Society For Biomaterials is a professional 

society that promotes advances in biomedical 

materials research and development by 

encouragement of cooperative research, 

educational programs, clinical application, and 

professional standards in the biomaterials field. 

Biomaterials scientists and engineers study 

cells, their components, complex tissues and 

organs, and their interactions with natural and 

synthetic materials and implanted prosthetic 

devices, as well as develop and characterize 

the materials used to measure, restore, and 

improve physiologic function, and enhance 

survival and quality of life. 

REGENERATE WORLD CONGRESS GUESTS ARE 

WELCOME TO CROSSOVER AND ATTEND SFB 

SESSIONS ON THURSDAY. 


EXHIBITORS 

As of press time, this exhibitor list 

was current. Be sure to visit 

www.regenerate-online.com 

for the most current 

list of exhibitors. 

AppTec’s ISO-certified, 

FDA-registered laboratories 

provide comprehensive 

biosafety testing and contract services for 

medical devices/products. Testing (GLP/cGMPcompliant) 

includes biocompatibility (in vivo 

and in vitro), chronic toxicity, genotoxicity, 

microbiology, chemistry, sterilization validation, 

viral clearance, environmental monitoring, and 

package testing; contract services include 

cGMP processing/manufacturing for tissue 

products and cell therapies. 

BioE ® is a biotechnology company 

dedicated to providing enabling, 

accessible tools for researchers 

interested in harnessing the poten - 

tial of adult stem cells. The company’s 

lead product, the Multi-Lineage 

Progenitor Cell (MLPC), is a 

genetically normal, multi-potent, clonal cell isolated 

from umbilical cord blood which could be 

used for development pathway analysis, stem 

cell research and regenerative medicine. 

INAMED Corporation develops, manufactures 

and markets 3-dimensional bio-scaffold 

matrices using purified type I collagen for 

tissue engineering, cell culture, medical and 

pharmaceutical applications. Collagen matrix 

products include PureCol, Nutragen, 

SphereCol and SpongeCol. INAMED'S 

products are manufactured in a cGMP facility. 

Material safety is assured by validated prion 

and viral inactivation processes. 

8 

Associates of Cape Cod Inc., is a key supplier of 

reagents and kits for testing for endotoxins and 

glucans for the pharmaceutical, biotechnology, 

dialysis and medical device industries. We also 

offer a number of contract testing and analytical 

services including biopharmaceutical profiling 

as well as our original endotoxin and glucan 

testing services. Booth # 110 

Artificial Organs: Replacement, 

Recovery & Regeneration (Blackwell 

Publishing) 

Since 1977, Artificial Organs has 

been publishing original articles featuring the 

studies of design, performance, and 

evaluation of the biomaterials and devices for 

the international medical, scientific, and 

engineering communities involved in the 

research and clinical application of artificial 

organ development. To subscribe, visit 

www.blackwellpublishing.com/aor. 

Battelle designs and develops customized, 

integrated, closed manufacturing systems that 

enable consistent clinical trial and commercial 

scale production of cell-based therapies and 

tissue engineered products. Our solutions 

economically address the challenges 

associated with isolation, purification, 

characterization, processing, expansion, 

manipulation, packaging and delivery of cells 

to patients. 

Bose Corporation manufactures the 

ElectroForce® Series test instruments using 

patented linear motor technology. These instruments 

are designed for characterizing soft tissues, 

bone, orthopaedic and cardiovascular 

medical devices, biomaterials, stents, and a 

variety of viscoelastic engineered materials. The 

new BioDynamic test instrument performs 

characterization of biomaterials and tissue in a 

biological environment. 

Cambrex provides 

innovative products 

and services that 

accelerate the discovery and commercialization 

of therapeutics. Cambrex offers products and 

services for the development and manufacture 

of APIs, biologics, cell therapies and cell culture 

media, drug discovery research and therapeutic 

testing. The Company employs approximately 

1900 worldwide. For more information, visit 

http://www.cambrex.com. 

The Georgia Tech/Emory 

Center (GTEC) for the 

Engineering of Living 

Tissues provides a unique 

blend of engineering and medical expertise to 

advance tissue engineering and regenerative 

medicine. GTEC is playing a leading role in 

developing the next generation of tissue engineered 

constructs, cell-based therapies, and 

advanced medical devices. 

Institute of Physics Publishing (IOP) is a not-forprofit 

organization dedicated to science communication. 

IOP provides a comprehensive 

range of products and services including an 

award-winning platform for electronic publishing. 

The newest addition to their collection of 

over 40 journals is Biomedical Materials: 

Materials for tissue engineering and regenerative 

medicine, details of which will be available 

at the booth. 

KTERMS was founded on July 1. 

1999 and the 8th Annual Meeting 

will be held on June 1, 2006 at 

Samsung Seoul Hospital. The 2nd 

TERMIS World Congress will be hosted 

by KTERMS on Aug 31 ~ Sept 3, 2009 at Hotel 

Lotte World Jamsil, Seoul, Korea. 

Lampire provides custom polyclonal 

and monoclonal antibody services, 

peptide synthesis, antibody purification 

and conjugation, cell culture, and 

immunoassay development to the 

biomedical community worldwide. 

Lampire also offers a novel cell culture bag, 

purified IgGs and secondary antibodies, plus a 

variety of blood products, tissues, and organs. 

Lifecore’s hyaluronan is 

a component in several 

commercial ophthalmic, 

orthopedic, and veterinary medical products. 

Lifecore supplies customers with either hyaluronan 

or finished products manufactured in its 

ISO 13485 and FDA certified aseptic filling facility. 

In addition, Lifecore’s hyaluronan is supplied 

to academic and corporate researchers around 

the world for basic science and product development 

research.

Exposition Hours 

Tuesday, April 25, 2006 

11:30 A.M. – 2:00 P.M. 

5:00 P.M. – 9:00 P.M. 

Wednesday, April 26, 2006 

7:00 A.M. - 8:30 A.M. 

11:30 A.M. – 2:00 P.M. 

Mary Ann Liebert, Inc., publishers is known for 

establishing authoritative peer-reviewed journals 

in promising areas of science and biomedical 

research such as Tissue Engineering 

(www.liebertpub.com/ten), the Official Journal of 

TERMIS, Tissue Engineering and Regenerative 

Medicine International Society. Tissue 

Engineering is a world class journal that brings 

the best of engineering, science and medicine 

together. Complimentary copies are available at 

the Mary Ann Liebert exhibit-booth 402. 

Mauna Kea 

Technologies 

develops a line of 

instruments based on fibered confocal fluorescence 

microscopy, designed for imaging living 

animals. The Cellvizio is a minimally invasive 

molecular imaging solution, with cellular resolution, 

that allows in vivo and in situ observation 

of tissue engineered constructs. 

The McGowan Institute 

serves as a single base of 

operations for the scientists 

and clinical faculty at the 

University of Pittsburgh and 

the University of Pittsburgh Medical Center 

working to develop tissue engineering, cellular 

therapies, and artificial & biohybrid organ 

devices. The Institute’s mission includes the 

development of innovative clinical protocols as 

well as the pursuit of the rapid commercial 

transfer of its technologies related to the repair 

or replacement of tissues and organs by incorporating 

the use of cells, genes or other biological 

building blocks along with bioengineered 

materials and technologies; for additional information, 

please see www.mcgowan.pitt.edu 

The National Institute of Biomedical 

Imaging and Bioengineering (NIBIB) 

leads the development and 

accelerates the application of 

emerging and breakthrough 

biomedical technologies in order to improve 

human health. The Institute is committed to 

integrating the engineering and physical 

sciences with the life sciences to advance 

basic research and medical care. 

NovaMatrix, a business 

unit of FMC 

BioPolymer, provides 

well-characterized, 

ultrapure alginate, chitosan and hyaluronate 

for use in drug delivery, tissue engineering, cell 

encapsulation, wound healing, and medical 

device applications, where functionality and 

regulatory documentation are important. 

These biopolymers may be used to form scaffolds, 

gels, beads, pastes, fibers, and films. 

Proxy Biomedical is 

a researcher and 

developer of biomaterials. 

Advanced implants, surgical instrumentation, 

and three-dimensional substrates have 

been developed using state-of-the-art materials 

and processes. The company manufactures 

to ISO 13485:2003 standards. Proxy 

Biomedical’s products enable researchers and 

clinicians to study, repair, augment, or regenerate 

tissue architectures for optimal tissue engineering 

outcomes. 

REGEN Biotech, Inc. 

pursues world leading 

Controlled Tissue 

Regeneration technology. Our innovative, 

value-added products improves the quality of 

life of people around the world. The company 

has three major products : scaffolds for tissue 

engineering, tissue regenerative functional 

proteins and functional natural products. 

New for 2006 

Regenerative Medicine provides a forum to 

address the important challenges in the 

exploding field of regenerative medicine. 

Senior Editor, Stephen Minger (Kings College 

London) and a panel of more than 60 international 

experts ensure that Regenerative 

Medicine delivers high-quality reviews, primary 

research and technology evaluations, all subject 

to rigorous peer review. 

For more information, see www.futuremedicine.com/loi/rme 

RheoGeneis dedicated 

to unlocking the power 

of cell and gene therapy to provide cures for 

major unmet medical needs. RheoGene is 

using its proprietary RheoSwitch® Therapeutic 

System (RTS) gene regulation and DirectIt 

recombinase technologies to develop safe, targeted 

and regulated cell and gene therapies." 

Scanco Medical in the leading manufacturer 

and global supplier of micro-CT scanners for 

research (CT 40, CT 80 and VivaCT 40) and 

clinical applications (XtremeCT). The scanners, 

together with built-in analysis and visualization 

software provide for a 3-dimensional, rapid and 

comprehensive quantitative measurements. 

Scanco Medical AG also offers contract based 

scanning services for academic and industrial 

groups. 

SurModics is 

designing platforms 

that can 

be used to augment 

or replace tissue or organ function, such 

cell encapsulation applications. For example, 

we are bringing innovation together with our 

partner, Novocell, to encapsulate pancreatic 

islet cells to deliver insulin to diabetics. 

Additionally, SurModics' regenerative technology 

platforms can be used to modify medical 

devices to facilitate tissue/organ recovery 

through natural repair mechanism. Examples 

include hemocompatible, biocompatible, and 

prohealing coatings. 

Zen-Bio provides high 

quality primary human 

adult stem cells and 

research reagents to 

scientists worldwide. 

For information about exhibiting: 

Contact LaShon Jackson at 

412.235.5116 

9

We would like to thank the following 

conference sponsors and partners 

SPONSORS 

STUDENT ACTIVITIES 

The Tissue Engineering and Regenerative Medicine-Student 

and Young Investigator Organization (TERMIS-SYIS) is proud to 

sponsor the following activities and workshop. 

Student Meet and Greet - Monday, April 24 

(open for all undergraduate, graduate and post-doc students) 

7:00pm-9:00pm - Marriot Courtyard 

Take advantage of this opportunity to meet and network with 

students and young investigators from around the world who 

are attending the World Congress. If you are a visiting scientist, 

please pick up your Pittsburgh Welcome Packet at this time. 

Complimentary beer, wine and appetizers will be served. 

Student Meet Mentor - Tuesday, April 25 

4:30pm-5:45pm - Westin Hotel 

This Student-Mentor happy hour and roundtable discussion 

allows students the opportunity for an open discussion with 

leaders in tissue engineering and regenerative medicine from 

academia and industry. Pre-registration is required. Check out 

www.regenerate-online.com for more details. 

10 

Professional Development Presentation 

Skills Workshop - Wednesday, April 26 

(open to TERMIS student/post doc members only) 

12:10pm-1:55pm - Westin Hotel 

This professional development workshop focuses on 

formulating and giving a scientific presentation in an 

international forum. Pre-registration is required and details are 

forthcoming. Check www.regenerate-online.com. 

Student Social Night - Wednesday, April 26 

(for all undergraduates, graduates and post-doc students) 

7:00pm-? - Hard Rock Café Pittsburgh 

Join fellow students at the Hard Rock Café, located in Station 

Square for a buffet, drinks and live music! This is a great 

opportunity for students to let loose and network in a casual 

atmosphere. Following the Hard Rock, enjoy the nightlife of 

Station Square. Pre-registration required. There is a nominal 

charge for each student that covers food, entertainment and 

transportation. 

For updated information about these events, and to 

register, visit www.regenerate-online.com

REGISTRATION AND ACCOMMODATIONS INFORMATION 

Regenerate World Congress Registration 

There are four ways to register: 

Online: www.regenerate-online.com 

Fax: 412-235-5120 

Mail: c/o PTEI; 100 Technology Drive, Suite 200; Pittsburgh, PA 15219 

Phone: 412-235-5116 

Registration Discounts Available 

1.Groups of three or more from the same institution are eligible for a 

discount. Please contact PTEI at 412-235-5116 for more details and 

fees. You may also email LaShon Jackson at ljackson@ptei.org for group 

discount information. 

2.To obtain more information on the combined discounted 

Regenerate/SFB registration fees, please visit www.regenerateonline.com. 

Admittance Badges 

Your admittance badge will be available on site at the conference 

registration desk. Badges will not be mailed in advance. 

Registration Confirmations 

A confirmation of your registration with information regarding the events, 

venues and visitor information will be provided after your registration has 

been processed and paid. 

Accommodations 

The Westin Convention Center Hotel All Attendees except for Students 

A block of rooms is being held for attendees of the 2006 Regenerate 

World Congress at a special group rate of $155.00 plus tax current 

state and local taxes of 14% on a single or double occupancy. 

Westin Convention Center Hotel 

1000 Penn Avenue; Pittsburgh, Pennsylvania 15222 

412-281-3700 phone; 412-227-4504 fax 

11 

Hotel Reservations 

Make lodging reservations online by visiting www.regenerate-online.com 

and accessing the custom website under Hotel and Travel. A deposit equal 

to one night’s stay is required to hold each individual reservation. The 

deposit is refundable with a seven (7) day advance cancellation, however 

deposits will be charged at the time of reservation. 

Cut Off Date 

To receive the special group rate of $155.00 single or double occupancy, 

reservations must be made by March 22, 2006. Reservations made after 

this date will be based on availability. 

Courtyard Pittsburgh Downtown - Students Only 

(Undergraduate and Graduate Only) 

A block of rooms is being held for students of the 2006 Regenerate World 

Congress at the special rate of $119.00 plus tax (14%) on a single or 

double occupancy at: 

Courtyard Pittsburgh Downtown 

945 Penn Avenue; Pittsburgh, PA 15222 

Phone: 412-434-5551; Fax: 412-992-5111 

Attendees may telephone in reservations (412-434-5551 or 800-321-2211), 

or make reservations online at www.courtyardpittsburghdowntown.com and 

utilize a seven character code for the World Congress rate (RWCRWCA - for 

a king bed; RWCRWCB - for doubles). In order to ensure the negotiated 

rate, individuals must make reservations prior to April 3, 2006, and must 

identify themselves as being with the Regenerate World Conference. 

Questions? 

Please contact LaShon Jackson at PTEI for assistance. LaShon can be 

reached at 412-235-5116 or by email at ljackson@ptei.org

How did you learn about the conference? mailer website email ad colleague other (specify:_____________________) 

Produced by Forecast Technology Group, Inc. 

www.conferencestrategists.com 

www.regenerate-online.com 

c/o PTEI 

100 Technology Drive, Suite 200 

Pittsburgh, PA 15219 

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