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Diploma Thesis THE IMMEDIATE INFLUENCE OF OSTEOPATHIC ...

Diploma Thesis THE IMMEDIATE INFLUENCE OF OSTEOPATHIC ...

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2.1.3.3 <strong>THE</strong> CF INTESTINES 16<br />

The intestine – usually a problem in infants, more rarely in adults.<br />

The biggest problems concerning the intestines usually are a meconium ileus (failure<br />

to pass the first stools (meconium) due to an obstruction of the terminal ileum) in<br />

newborns, and a meconium ileus equivalent syndrome (distal intestinal obstruction<br />

syndrome or DIOS) or a rectum prolapse (the lining of the rectum pushes out through<br />

the anus), which are common in infants and small children. These symptoms often<br />

are the first indicators for CF.<br />

The most important clinical findings and hints from the case history pointing towards<br />

DIOS are: alternating stool consistency, a bloated abdomen which is sensitive to<br />

touch, abdominal pain and vomiting.<br />

In childhood and as adults CF patients often suffer from chronic constipation. In CF<br />

patients who have a persistent anaemia, failure to thrive (FTT) and frequent<br />

diarrhoea despite an adequate enzyme supplementation and nutrient supply the<br />

additional diagnosis of coeliac disease should be considered. Coeliac disease can<br />

also be a first hint pointing towards CF.<br />

Chronic inflammatory diseases of the intestines like ulcerative colitis and Crohn’s<br />

disease occur frequently in CF patients.<br />

The risk for a CF patient to develop a malign carcinoma in the gastrointestinal tract is<br />

about 6.5 times higher than in the comparable healthy population group.<br />

16 Reinhardt et al., 2001, p.382-396<br />

<strong>Diploma</strong> <strong>Thesis</strong> Sabine Neuhaus page 13 of 52

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