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Agilent 7000A Triple Quadrupole GC/MS
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Agilent 7000A Triple Quadrupole GC/MS
Extraordinary sensitivity and selectivity—day after day.
Agilent’s new 7000A Triple Quadrupole GC/MS delivers lower limits of detection and advanced high-speed GC/MS/MS
quantification, even with the dirtiest samples in the most demanding environments. Engineered from the ground up as an
easy-to-use GC/MS Triple Quad for routine high performance operation, this breakthrough system is the ideal choice for
labs requiring maximum sensitivity, maximum uptime, and maximum productivity.
The Agilent 7000A Triple Quadrupole GC/MS combines industry-leading
reliability with femtogram-level sensitivity in complex matrices.
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66 71 216 221 500 505
Industry-leading sensitivity and selectivity
Whether you are measuring pesticides in food and water, drugs in
complex biological matrices, or contaminants in environmental
samples, the 7000A system helps you meet the increasing demand for
trace-level detection of target analytes. The combination of Agilent’s
proprietary solid inert ion source, proven quartz quadrupoles, innovative
collision cell design, and new triple-axis detector provides:
• Routine femtogram-level sensitivity
• Superior selectivity
• Ultra-low noise
• Outstanding data acquisition speed
Faster analysis, higher throughput
Acquisition speeds of up to 500 MRM transitions per second
match the front-end performance of the fastest chromatography
without compromising data quality—enabling you to automatically
quantify and confirm more targets in a single method. Powerful,
easy-to-use data analysis, review and reporting tools let you process
more samples in less time with complete confidence in your results.
Day-after-day reliability and simple operation
So that every laboratory can take advantage of the advanced
capabilities of the 7000A Triple Quad, the system incorporates
proven, highly reliable technology developed specifically for
GC/MS applications. For example, the rugged inert ion source, the
differentially pumped configuration, and the heated, gold-plated
hyperbolic quartz quadrupoles keep routine MS maintenance to
a minimum. Advanced set-up, configuration, proven AutoTune
technology, and powerful manual tuning tools enable quick start-up
for quantitative analyses.
Mass 69.00
ab 426330
Mass 218.00
ab 362315
Mass 502.00
ab 45942
Inert, ultra-reliable ion source
Agilent’s unique, dual-filament ion source
design increases productivity and reduces
cleaning requirements, especially when
analyzing dirty samples. Programmable up
to 350˚C, the source is solid inert material—
not a coating—so you can run sample after
sample with complete confidence.
Proprietary gold quartz quadrupole
with 1050 u mass range
Agilent’s proprietary gold-plated hyperbolic
quartz quadrupole analyzer offers high
temperature stability and can be heated to
200°C. Because the quadrupole can be kept
at this high temperature and at vacuum, it stays
clean even with the complex, high boiling
samples—eliminating frequent retuning
time-consuming maintenance and ensuring
superior mass analyzer performance.
New, proprietary hexapole
collision cell technology
The linear acceleration design and novel
helium-quenched system reduces neutral
noise and contributes to outstanding highspeed
performance without ion ghosting or
cross-talk. A wide mass bandwidth optimizes
sensitivity at all masses while eliminating the
need to tune on your compound.
High S/N Triple-Axis Detector
Agilent’s next-generation off-axis, triple-channel
detector minimizes noise and maximizes signal
for the lowest detection limits. The same
field-proven design is currently incorporated
in all Agilent 5975C GC/MSD systems.
High-sensitivity AutoTune
Simple, automatic tuning takes the trial
and error out of system setup. It saves time,
simplifies operation and improves instrumentto-instrument
consistency. Optimizing ion
transmission, mass axis calibration, mass
resolution, and detector gain-vs.-voltage
significantly boosts performance, as well.
You can also perform a manual tune if desired
using simple powerful tools.
For additional instrument specifications go to:
www.agilent.com/chem/7000A
5989-9625EN: Agilent 7000A GC/MS Triple Quadrupole System Data Sheet
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Advanced technologies translate
into everyday high performance.
Analysis of 100 femtograms
of OFN at >100:1 RMS S/N
This EI MRM specification will be
demonstrated on-site at installation
using AutoTune conditions.
Unprecedented sensitivity
for target compounds
Chromatogram of two PCB congeners
(PCB 153 and PCB 138) injected at 400 fg
each on-column. Quantitation transition
360—>290 m/z, with the qualifier
transition measured at 360—>325 m/z
for simultaneous quantitation and
confirmation at the lowest detection limit.
Multiple Reaction Monitoring
(MRM) helps you make sense
of complicated samples at the
lowest detection limits
Chromatogram of multiple PCB congeners in
mussel extract measured at 2 pg on column.
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Exceptional selectivity and unquestionable
quantitation—even in the most difficult matrices
Measurement of Chlorpyriphos in Pu-erh tea at a 10 ppb spike.
Tea extract is one of the most complex samples in food safety,
yet the MS/MS chromatogram is remarkably clean.
Outstanding sensitivity and selectivity—
down to 1 pg on column
Overlay of multiple injections at three different concentrations
from extracts of dried Ashitaba herbs. The analysis also
highlights the exceptional GC retention time reproducibility
of the Agilent 7890A GC.
Area 1 1197
Area 2 1280
Area 3 1347
Area 4 1186
Area 5 1291
Mean 1260
RSD% 5.4
Outstanding reproducibility at trace levels
The organophosphorus insecticide, Cyanophos, spiked into garlic
at 0.5 ppb and analyzed in MRM mode. Overlay of 5 injections
showing the quantitation transition 243-109 m/z.
Easy quantitation even in sediment samples
Easy to quantify MS/MS chromatograms in the most difficult
environmental samples.
To learn more about the Agilent 7000A Triple Quadrupole GC/MS, visit www.agilent.com/chem/7000A
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New MassHunter software helps you make the
most of every run and every workday.
To make it easy even for non-expert operators to take full advantage of the advanced capabilities of the Agilent
7000A Triple Quadrupole system, we’ve teamed up Agilent’s proven acquisition and control interface with the
powerful MassHunter data analysis and reporting software.
An intuitive user interface enables powerful compound-centric data navigation, “Batch at a Glance” data
review and fast peak integration with quantitation. Consistent software across all Agilent MS platforms
improves productivity by shortening learning curves and reducing training costs.
Single-screen acquisition and control.
A single screen gives you access to all instrument
setup and data acquisition parameters.
Powerful MassHunter data analysis. Agilent MassHunter
software incorporates advanced “Batch at a Glance”
quantitative data analysis, a proven reliable parameter-less
integrator, and other tools that enable you to quickly and
completely analyze data from large sample sets. Qualitative
analysis tools include a novel spectral library editor and
search routines. Identifications can be achieved from scan
data via a new deconvolution program.
Flexible, fully customizable reports. MassHunter software
stores all results in XML files and uses Microsoft Excel
and a custom macro add-in for reporting. A wide range of
application-specific report templates or customized reports
are available in this familiar Excel environment, including
custom calculations to meet specific needs.
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Agilent 7890A GC: Critical success
factor for GC/MS/MS analysis.
Agilent’s new 7890A GC is the perfect front-end for the
7000A Triple Quadrupole system. The industry-leading
GC gives you everything you need to take your lab to the
next level of GC/MS/MS performance, including advanced
chromatographic capabilities, and powerful new productivity
features, such as Capillary Flow Technology. Plus, of course,
legendary Agilent reliability.
Agilent performance and reliability
Fifth-generation electronic pneumatics control (EPC) and
digital electronics set a new benchmark for retention time,
precision, and repeatability and help make the 7890A
Agilent’s most dependable GC ever.
Higher productivity
Faster oven cool-down, advanced automation features, and
faster GC oven ramps let you get more done in less time, at
the lowest possible cost per sample—all easily incorporated
into your existing methods.
Agilent Capillary Flow technology
Available in a number of useful
configurations, Agilent’s inert,
low-dead volume Capillary Flow
devices open the door to highly useful
techniques such as “QuickSwap”
column change-out, flow splitting,
backflushing, and Deans switching
that can save time and resources
and improve your analytical results.
Backflushing shortens analysis time by 33 minutes.
In this analysis, the lower trace employing oven bakeout
takes an additional 33 minutes at 320°C to remove
high boilers that elute after the analytes of interest.
Backflushing (upper trace) removes all the high boiling
components in seven minutes, at only 280°C.
Backflush capability improves data quality, while shortening
cycle time and increasing column life. It reduces ion
source contamination by keeping excess column bleed
and heavy residues from being introduced into the mass
spectrometer. It also eliminates ghost peaks, providing
a significant improvement in data integrity.
To learn more about the Agilent 7000A Triple Quadrupole GC/MS, visit www.agilent.com/chem/7000A
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Faster, better GC/MS results with high
performance Agilent J&W columns
Choose Agilent J&W Ultra
Inert columns for exceptionally
low column bleed providing
improved signal-to-noise ratio
and sensitivity for the detector,
fast baseline stabilization for
minimized conditioning time, and excellent thermal stability
for reduced instrument downtime.
Agilent supplies help keep routine
maintenance routine
An exclusive non-stick plasma on our premium inlet septa
and pre-cleaned O-rings makes maintenance quicker and
easier—no unscheduled inlet maintenance due to residue
on the inlet surface, shorter bakeout times after preventive
maintenance, so you can start running samples sooner.
Agilent Services keep your lab running
at peak productivity
With a 98% customer satisfaction rating, Agilent’s service
engineers are the most respected-and best-trained-in the
industry. Whether you need support for a single instrument
or a multi-lab, multi-vendor operation, we can help you solve
problems quickly, increase your uptime, and optimize your
lab’s resources. Through a selection of service plans tailored
to your lab’s needs and budget, we provide:
• On-site preventive maintenance that ensures dependable
system operation and minimizes unplanned downtime
For more information
Learn more:
www.agilent.com/chem/7000A
Buy online:
www.agilent.com/chem/store
Find an Agilent customer center in your country:
www.agilent.com/chem/contactus
U.S. and Canada
1-800-227-9770
agilent_inquiries@agilent.com
Europe
info_agilent@agilent.com
Asia Pacific
adinquiry_aplsca@agilent.com
Research use only. Information, descriptions, and specifications in this publication are
subject to change without notice. Agilent Technologies shall not be liable for errors
contained herein or for incidental or consequential damages in connection with the
furnishing, performance, or use of this material.
© Agilent Technologies, Inc. 2008
Printed in USA October 3, 2008
5990-3152EN
• Available remote diagnostic and monitoring capabilities that
give you additional “uptime insurance”
• Expert installation, familiarization and advanced training to
get you up and running as quickly as possible, and to make
sure you get the most from your new Agilent equipment