Dr Richard Carr

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Tips • Artefacts may dominate appearances • Do NOT commit to diagnosis on initial biopsy if evidence insufficient • Ask for another (bigger) biopsy • Dermatologist usually right BUT NOT ALWAYS • Don’t be afraid to make other suggestions but try to think clinically • If a definitive diagnosis is not possible offer suggestions weighting the differential diagnostic possibilities
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Histological Approach to the Diagno
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•Definitions •General Approach
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Definititions: Psoriasiform Epiderm
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Akerman: Algorithmic Approach • I
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Diagnostic Approach to Inflammatory
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Diagnostic Approach to Inflammatory
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LEARNING POINTS Dermatologists rare
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Lever • Mutli-author has it’s d
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Mckee & Calonje 4 th 2012 • Clini
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Excoriation only...
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Lichenification (Lichen Simplex Chr
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Lichen Simplex Chronicus • Locali
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Nodular Prurigo / Pseudoepithelioma
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F86 Left ankle lesion. Biopsy prove
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Diagnosis Polypoid eccrine poroma w
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Spongiotic Dermatoses 42
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Eczematous (Spongiotic) Dermatitis
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Eczematous (Spongiotic) Dermatitis:
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Subacute/Chronic Spongiotic Psorias
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M85. Raised annular patch with cent
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Discoid (Nummular) Dermatitis • S
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Acute spongiotic vesicular dermatos
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Autosensitization (Id) Reaction •
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Learning Points • Dermatologist u
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Mounds of parakeratosis (with neutr
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Seborrhoeic Dermatitis 2 • Sharpl
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M63. Two year hx itchy rash. Improv
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RAC3257
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Multiple levels examined Serum extr
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Contact Dermatitis Suggested by his
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Other Conditions with • Pityriasi
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Layered parakeratosis with neutroph
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Diagnosis Dermatophytosis PAS
Page 78 and 79: Spongiotic: Variants 1. Eosinophili
Page 80 and 81: F80. Urticated blistering eruption,
Page 82 and 83: Neutrophilic Spongiosis • Irritan
Page 84 and 85: • PROBLEM • Psoriasis (Reiter
Page 86 and 87: Layered parakeratosis Increased & m
Page 88 and 89: F57. Trunk. Generalised pustular ra
Page 90 and 91: Generalised (eruptive / pustular)
Page 92 and 93: F61. Hip. Small areas of itchy red
Page 94 and 95: Not suggestive or eczematous or DH
Page 96 and 97: Psoriasis Early • Parakeratotic m
Page 98 and 99: Layered parakeratosis Absent granul
Page 100 and 101: Psoriasis v’s Eczematous Acral /
Page 102 and 103: RAC2963
Page 104 and 105: Diagnosis Chronic hyperplastic muco
Page 106 and 107: Psoriasis: Differential Diagnosis
Page 108 and 109: Focal parakeratosis Intact granular
Page 110 and 111: Pityriasis Rubra Pilaris • Burnin
Page 112 and 113: PRP: Follicular Papules • Conical
Page 114 and 115: M65. Ankle. Chronic liver disease.
Page 116 and 117: “Marked hyper- and parakeratosis
Page 118 and 119: Acrodermatitis Enteropathica (Zinc
Page 120 and 121: Necrolytic Migratory Erythema Rev.
Page 122 and 123: Thank-You • Dr Phillip Mckee •
Page 124 and 125: • PAS for fungi Special Stains
Page 126 and 127: Immunos • Pan-keratin for macular
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Dr Richard Carr

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