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Cisplatin and Etoposide chemotherapy in combination with ... - SCAN

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1<br />

6<br />

Y<br />

our oncologist has recommended that you should<br />

receive both <strong>chemotherapy</strong> <strong>and</strong> radiotherapy to try <strong>and</strong><br />

cure your lung cancer. This <strong>in</strong>formation leaflet is<br />

designed to help you underst<strong>and</strong> more about the treatment.<br />

Your <strong>chemotherapy</strong><br />

This <strong>chemotherapy</strong> regime consists of 4 courses (cycles) of<br />

<strong>chemotherapy</strong> <strong>with</strong> radiotherapy usually delivered <strong>with</strong> the<br />

2 nd <strong>and</strong> 3 rd cycles. The 4 th cycle of <strong>chemotherapy</strong> starts when<br />

your radiotherapy has f<strong>in</strong>ished. A ‘cycle’ of <strong>chemotherapy</strong> lasts<br />

3 weeks (days 1-21). The <strong>chemotherapy</strong> is given as an outpatient<br />

<strong>in</strong> Ward 1 at the Ed<strong>in</strong>burgh Cancer Centre.<br />

The <strong>chemotherapy</strong> consists of 2 drugs, <strong>Cisplat<strong>in</strong></strong> <strong>and</strong><br />

<strong>Etoposide</strong>.<br />

<strong>Cisplat<strong>in</strong></strong> is adm<strong>in</strong>istered on the 1 st day of each treatment cycle<br />

<strong>and</strong> is given over 2 hours <strong>with</strong> a bag of fluid <strong>in</strong>to a cannula <strong>in</strong><br />

your arm. You will be connected to a drip for a few hours<br />

before receiv<strong>in</strong>g the <strong>Cisplat<strong>in</strong></strong>.<br />

<strong>Etoposide</strong> is given on days 1, 2 <strong>and</strong> 3 of each cycle, aga<strong>in</strong> as a<br />

drip <strong>in</strong>to your arm. This is given over 2 hours.<br />

This <strong>chemotherapy</strong> is usually well tolerated but like all cancer<br />

treatments can have some side-effects.<br />

Side effects of <strong>chemotherapy</strong><br />

1. Tiredness - all cancer treatments can make you quite<br />

fatigued. We will give you advice on how best to deal<br />

<strong>with</strong> this.<br />

Concurrent chemo-radiation<br />

Cycle 1 Cycle 2 Cycle 3 Cycle 4<br />

<strong>Cisplat<strong>in</strong></strong> & <strong>Etoposide</strong><br />

1<br />

<strong>Etoposide</strong><br />

<strong>Etoposide</strong><br />

<strong>Cisplat<strong>in</strong></strong> & <strong>Etoposide</strong><br />

<strong>Etoposide</strong><br />

<strong>Etoposide</strong><br />

<strong>Etoposide</strong><br />

<strong>Cisplat<strong>in</strong></strong> & <strong>Etoposide</strong><br />

week 1 week 4 week 7 week 10<br />

50Gy <strong>in</strong> 20 fractions<br />

4 Weeks<br />

You will be assessed before each <strong>chemotherapy</strong> treatment,<br />

<strong>and</strong> assessed by a nurse weekly dur<strong>in</strong>g radiotherapy. Once<br />

completed, your lung cancer nurse will phone you weekly prior<br />

to be<strong>in</strong>g seen at the cl<strong>in</strong>ic 4-6 weeks after complet<strong>in</strong>g your<br />

treatment. This is to check that you are recover<strong>in</strong>g from the side<br />

effects of your treatment. You will then be seen 3-4 months<br />

later <strong>with</strong> a CT scan of your chest to assess the response to<br />

treatment.<br />

<strong>Etoposide</strong><br />

<strong>Cisplat<strong>in</strong></strong> & <strong>Etoposide</strong><br />

<strong>Etoposide</strong><br />

2 3 1 2 3 1 2 3 1 2 3<br />

<strong>Etoposide</strong><br />

12 weeks

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