final report - ARCHIVE: Defra

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Department for Environment, Food and Rural Affairs Nobel House 17 Smith Square London SW1P 3JR Telephone: 020 7238 6000 Website: www.defra.gov.uk © Crown copyright 2008 Copyright in the typographical arrangement and design rests with the Crown. This publication (excluding the logo) may be reproduced free of charge in any format or medium provided that it is reproduced accurately and not used in a misleading context. The material must be acknowledged as Crown copyright with the title and source of the publication specified. This document is also available on the <strong>Defra</strong> website. Published by the Department for Environment, Food and Rural Affairs. Printed in the UK, November 2008, on material that contains a minimum of 100% recycled fibre for uncoated paper and 75% recycled fibre for coated paper. PB 13162 Front cover: Coloured SEM of a macrophage (green) engulfing cells of Mycobacterium bovis (orange). Science Photo Library
The Society for General Microbiology Independent Overview of Bovine Tuberculosis Research in the United Kingdom; a <strong>Defra</strong> Sponsored Review REVIEW GROUP Professor Mike Barer (co-chairman) University of Leicester Professor Charles Penn (co-chairman) University of Birmingham Dr Greg Bancroft London School of Hygiene and Tropical Medicine Professor Chris Garforth University of Reading Professor George Gunn Scottish Agricultural College Inverness Professor Tim Roper University of Sussex Professor Neil Stoker Royal Veterinary College London Professor Rick Titball University of Exeter SECRETARIAT Dr Ron Fraser Mrs Janet Hurst Society for General Microbiology, Reading COPY-EDITING AND DESIGN Dr Melanie Scourfield Mrs Jane Perugia Mr Ian Atherton Society for General Microbiology, Reading
Page 1: The Society for General Microbiolog
Page 6 and 7: 4.5 Environmental reservoirs of Mb
Page 8 and 9: Summary of recommendations Finally,
Page 10 and 11: Summary of recommendations 15 Resea
Page 13 and 14: 1 INTRODUCTION Bovine tuberculosis
Page 15 and 16: 2 DIAGNOSIS 2.1 Current and recent
Page 17 and 18: Diagnosis 2.3.2 Conventional micros
Page 19 and 20: Diagnosis 2.5 Strain definition in
Page 21: Diagnosis of bTB. If test results f
Page 24 and 25: Pathogenesis 2008. Consideration of
Page 26 and 27: Pathogenesis where the expression o
Page 28 and 29: Pathogenesis different mycobacteria
Page 31 and 32: 4 ENVIRONMENT AND EPIDEMIOLOGY 4.1
Page 33 and 34: Environment and epidemiology provid
Page 35 and 36: Environment and epidemiology the po
Page 37 and 38: Environment and epidemiology Transm
Page 39 and 40: Environment and epidemiology Transm
Page 41 and 42: 5 VACCINES 5.1 Current and recent r
Page 43 and 44: Vaccines 5.2 Evidence that vaccines
Page 45 and 46: Vaccines based on attenuated Mtb, b
Page 47 and 48: Vaccines investigate adjuvants for
Page 49 and 50: 6 ECONOMIC, SOCIAL AND BEHAVIOURAL
Page 51 and 52: Economic, social and behavioural co
Page 53:
Economic, social and behavioural co
Page 56 and 57:
Management tools data implicates a
Page 58 and 59:
Management tools that (a) reactive
Page 60 and 61:
Management tools 7.6.3 An additiona
Page 63 and 64:
8 REFERENCES Alonso-Hearn, M., Pate
Page 65 and 66:
References Ernst, J. D., Trevejo-Nu
Page 67 and 68:
References Varley, S. & other autho
Page 69:
References of fertility control and
Page 72 and 73:
Research projects funded by Defra c
Page 75:
Appendix 1 Documents made available
Page 78 and 79:
Appendix 2 SGM SNP TB TNF TraSH TST
Page 80 and 81:
Appendix 3 Keeping members informe
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final report - ARCHIVE: Defra

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