JSB Market Research: Mice Model Market - by Type, Technology, Disease, Service & Care Products- Forecasts to 2018

JSB Market Research: Mice Model Market - by Type, 

Technology, Disease, Service & Care Products- 

Forecasts to 2018 

On 10 th July 2014 

Summary 

The global mice model market is segmented on the basis of type, technology, 

disease, and mice model services. By type, the market comprises of inbred, 

outbred, knockout, conditioned/surgically modified, hybrid/congenic, and 

spontaneous mutant mice. 

The market for mice model services is segmented into breeding, cryopreservation, 

quarantine, rederivation, genetic testing, model in-licensing, and other services 

(surgical and line rescue). Based on geography, the market is divided into North 

America, Europe, Asia, and the Rest of the World (RoW). 

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The biggest factor that is likely to drive the growth of this market is the ongoing 

innovations in the development of mice models. In addition, another factor that is 

likely to drive the growth of the market is the continuous research that is 

undertaken to develop treatments for fatal diseases such as cancer and HIV/AIDS. 

Furthermore, research institutes and government bodies have extended their 

help in the form of investments, funds, and grants, which have stimulated 

research activities to develop mice models. In addition, the demand for 

personalized medicines is expected to boost the use of humanized mice models. 

A number of factors such as advancements in the biotechnology and 

biopharmaceutical industries as well as the increase in the number of R&D activities 

in pharmaceutical industries are propelling the growth of the mice model market. 

However, stringent regulations and laws for ethical use of animals in research are 

hindering the growth of this market. In addition, the market is facing a threat from 

advances in zebrafish models and rat models, which are leading to their increased 

use in research activities. 

North America is the largest market for mice models, followed by Europe and Asia. 

Furthermore, the Asian and North American markets for mice models are expected 

to witness a healthy growth over the next five years. 

The major players in the market include Charles River Laboratories (U.S.), The 

Jackson Laboratory (U.S.), Taconic farms, Inc. (U.S.), genOway S.A. (France), Covance, 

Inc. (U.S.), Crescendo Biologics Limited (U.K.), Deltagen, Inc. (U.S.), Harbour 

Antibodies BV (The Netherlands), Harlan Laboratories, Inc. (U.S.), TransGenic, Inc. 

(U.S.), SAGE Labs (U.S.), inGenious Targeting Laboratory, Inc. (U.S.), Lexicon 

Pharmaceuticals, ImmunoGenes AG (Switzerland), Mirimus, Inc. (U.S.), and Ablexis 

LLC (U.S.). 

Scope of the Report 

This research report categorizes the global mice model market into the following 

segments and sub-segments: 


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By Type 

Inbred Mice 

Outbred Mice 

Conditioned/Surgically Modified Mice 

Hybrid/Congenic Mice 

Knockout Mice 

Spontaneous Mutant Mice 

By Technology 

Microinjection 

Embryonic Stem Cell Injection 

Virus/Vector Mediated Gene Transfer 

Nuclear transfer Technology 

Genetically Modified Sperm 

Others 

By Disease 

Oncology 

Immunology & Inflammation 

Central Nervous System 

Cardiovascular 

Diabetes 

Metabolism & Regulation 

Others 

By Service 

Breeding 

Cryopreservation 

Quarantine 

Rederivation 


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Genetic Testing 

Model In-licensing 

Other Services (Surgical and Line Rescue) 

By Geography 

North America 

Europe 

Asia 

RoW 

Mice Care Products Market, by Segment 

Bedding 

Feed 

Cages 

Others 

Table of Contents: 

1 Introduction (Page No. - 35) 

1.1 Markets Covered 

1.2 Stakeholders 

1.3 Research Methodology 

2 Summary 

(Page No. - 51) 


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3 Market Dynamics (Page No. - 60) 

3.1 Drivers 

3.1.1 Ongoing Innovations in Mice Models 

3.1.2 Investments and Grants 

3.1.3 Personalized Medicine to Fuel The Demand For Personalized Humanized 

Mice Models 

3.1.4 Associations Propelling The Development of Embryonic Stem Cells (Es Cells) 

As Well As Knockout and Mutant Mice 

3.1.5 Global Conferences and Meetings Stimulate Market Growth 

3.1.6 Genetic Similarity of Mice to Humans 

3.1.7 Advancements in Biotechnology and Biopharmaceutical Industries 

3.1.8 Increase in R&D Activities in Pharmaceutical Industries 

3.2 Threats 

3.2.1 Advances in Zebrafish Model Development 

3.2.2 Increased Usage of Rat Models 

3.2.3 Increased Benefits From Cryopreservation Is Likely to Hamper The Demand 

For Mice Models 

3.2.4 Alternative Methods to Animal Testing 

3.3 Barriers 


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3.3.1 Regulations and Laws For Ethical Use of Animals in Research 

3.4 Opportunities 

3.4.1 Upsurge in Research Involving Humanized Mice 

3.4.2 Increase In Monoclonal Antibody Production 

3.5 Challenges 

3.5.1 Need For Improved Mice Models 

4 Market Share Analysis, By Key Players (Page No. - 76) 

5 Mice Model Market Size (Page No. - 89) 

5.1 Market By Type 

5.1.1 Introduction 

5.1.2 Inbred Mice 

5.1.3 Outbred Mice 

5.1.4 Hybrid/Congenic Mice 

5.1.5 Spontaneous/Mutant Mice 

5.1.6 Knockout Mice 

5.1.7 Conditioned/Surgically Modified 

5.2 Market By Technology 


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5.2.2 Micro-Injection 

5.2.3 Embryonic Stem Cell Injection 

5.2.4 Nuclear Transferase Technology 

5.2.5 Viruses/Vectors 

5.2.6 Genetically Modified Sperms 

5.2.7 Others 

5.3 Market By Disease 


5.3.2 Oncology 

5.3.3 Immunology and Inflammation 

5.3.4 Diabetes 

5.3.5 Cardiovascular 

5.3.6 Central Nervous System 

5.3.7 Metabolism and Regulation 

5.3.8 Others 

5.4 Market By Service 


5.4.2 Breeding 


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5.4.3 Cryopreservation 

5.4.4 Quarantine 

5.4.5 Rederivation 

5.4.6 Genetic Testing 

5.4.7 Model in Licensing 

5.4.8 Others 

5.5 Mice Care Products Market, By Segment 


5.5.2 Cages 

5.5.3 Bedding 

5.5.4 Feed 

5.5.5 Others 

6 Geographic Analysis (Page No. - 148) 

6.1 Introduction 

6.2 North America 

6.2.1 Investments in The Development of Mice Models to Increase Their 

Application Areas 

6.2.2 Growing Biomedical Research in The U.S.to Boost The Market 


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6.2.3 Preclinical Activities By Cros and Pharmaceutical R&D to Propel The Market 

6.2.4 Growth in Rare Diseases to Create Demand For Mice Models 

6.2.5 Mexico- Production Hub For Global Pharmaceutical Companies 

6.3 Europe 

6.3.1 Need For Better Mice Models to Trigger Investments and Innovation 

6.3.2 Growth in Biosimilars Market Calls For Increased Preclinical Activities 

6.3.3 Events Conducted By Animal Care Associations to Promote The Ethical Use 

of Mice 

6.3.4 Increase in Tailored Mice Models For Cancer and Rare Disease Projects 

6.4 Asia 

6.4.1 Less Stringent Laws Creates A Potential For Outsourcing of Animal Models 

and Services 

6.4.2 Growth in Translational Research in Singapore to Fuel The Market 

6.4.3 Increasing R&D Activities Provide Impetus to Preclinical Research 

6.4.4 Mandatory Animal Testing For All Pharmaceutical Drugs and Cosmetics in 

China 

6.4.5 Growth in Regenerative Medicine, Biomedical, and Medical Research in 

Japan 

6.4.6 Increase in Neuroscience Research in Malaysia 

6.4.7 Government-Supported Strong Academic and Commercial R&D Activities in 

Taiwan 


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6.4.8 Rising Pharmaceutical and Biotechnology R&D Activities in Korea 

6.5 ROW 

6.5.1 Pharmaceutical, Biotechnology, and Research industries in Brazil to Bolster 

The Market 

6.5.2 Ongoing Biomedical Research Activities in Australia and New Zealand to 

Strengthen The Market 

6.5.3 Favorable Business Environment For Pharmaceutical and Biotechnology 

industries in Saudi Arabia and Uae 

7 Competitive Landscape (Page No. - 207) 

7.1 Competitive Developments Mapping 

7.2 Agreements, Partnerships, Collaborations, and Joint Ventures 

7.3 Licensing 

7.4 Grants and Funds 

7.5 Marketing and Promotion 

7.6 Expansions 

7.7 Patents 

7.8 Others 

8 Company Profiles (Page No. - 245) 


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8.1 Ablexis, LLC 

8.2 Charles River Laboratories, Inc. 

8.3 Covance, Inc. 

8.4 Crescendo Biologics, 

8.5 Deltagen, Inc. 

8.6 Genoway Sa 

8.7 Harbour Antibodies Bv 

8.8 Harlan Laboratories, Inc. 

8.9 Immunogenes Ag 

8.1 Ingenious Targeting Laboratory 

8.11 Lexicon Pharmaceuticals, Inc. 

8.12 Mirimus, Inc. 

8.13 Taconic Farms, Inc. 

8.14 The Jackson Laboratory 

8.15 Transgenic, Inc. 

8.16 Sage Labs 

9 Preclinical Pipeline (Page No. - 299) 


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10 Industry Speaks (Page No. - 314) 

11 Cost Assessment and Mouse Model Outlicensing/Buyer Companies 

Assessment (Page No. - 230) 

11.1 Cost of Maintaining A Transgenic Mouse Colony 

11.2 List of Mouse Model Outlicensing/Buyer Companies 

List of Tables 

Table 1 Primary Research Sampling Frame 

Table 2 Global Mice Model and Mice Care Products Market, 2013- 2018 

($Million) 

Table 3 Global Mice Model Market, By Geography, 2013-2018 ($Million) 

Table 4 Global Market By Type, 2013 2018 ($Million) 

Table 5 Inbred Market, By Geography, 2013 2018 ($Million) 

Table 6 Knockout Mice Model Market, By Geography, 2013 2018 ($Million) 

Table 7 Outbred Mice Model Market, By Geography, 2013 2018 ($Million) 

Table 8 Hybrid/Congenic Mice Model Market, By Geography, 2013 2018 

($Million) 

Table 9 Spontenous Mutant Mice Model Market, By Geography, 2013 2018 

($Million) 


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Table 10 Conditioned/Surgically Modified Mice Model Market, By Geography, 

2013 2018 ($Million) 

Table 11 Global Market, By Technology, 2013 2018 ($Million) 

Table 12 Microinjection Based Mice Model Market, By Geography, 2013 2018 

($Million) 

Table 13 Embryonic Stem Cell Injection Based Mice Model Market, By Geography, 


Table 14 Virus/Vector-Mediated Gene Transfer Based Mice Model Market, By 

Geography, 2013 2018 ($Million) 

Table 15 Nuclear Transfer Technology Based Mice Model Market, By Geography, 


Table 16 Genetically Modified Sperm Based Mice Model Market, By Geography, 


Table 17 Other Technology Based Mice Model Market, By Geography, 2013 2018 

($Million) 

Table 18 Global Market, By Disease, 2013 2018 ($Million) 

Table 19 Oncology Mice Model Market, By Geography, 2013 2018 ($Million) 

Table 20 Immunology & Inflammation Mice Model Market, By Geography, 2013 

2018 ($Million) 

Table 21 Central Nervous System Mice Model Market, By Geography, 2013 2018 

($Million) 

Table 22 Cardiovascular Mice Model Market, By Geography, 2013 2018 ($Million) 

Table 23 Diabetes Mice Model Market, By Geography, 2013 2018 ($Million) 


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Table 24 Metabolism & Regulation Mice Model Market, By Geography, 2013 


Table 25 Other Diseases Mice Model Market, By Geography, 2013 2018 ($Million) 

Table 26 Global Market, By Service, 2013 2018 ($Million) 

Table 27 Global Market By Type, By Geography, 2013 2018 ($Million) 

Table 28 Breeding Services Market, By Geography, 2013 2018 ($Million) 

Table 29 Cyropreservationservices Market, By Geography, 2013 2018 ($Million) 

130 

Table 30 Quarantine Services Market, By Geography, 2013 2018 ($Million) 

Table 31 Rederivation Services Market, By Geography, 2013 2018 ($Million) 

Table 32 Genetic Testingservices Market, By Geography, 2013 2018 ($Million) 

Table 33 Model in-Licensingservices Market, By Geography, 2013 2018 ($Million) 

Table 34 Otherservices Market, By Geography, 2013 2018 ($Million) 

Table 35 Global Mice Care Products Market By Segment, 2013 2018 ($Million) 

Table 36 Global Mice Care Products Market, By Geography, 2013 2018 ($Million) 

Table 37 Global Venture Financing For Preclinical Activities in U.S. 

Table 38 Innovation Centers Set Up in U.S. 

Table 39 Collaborations For Preclinical Activities in The Year 2013 For U.S. Based 

Companies 

Table 40 Grants and Contracts For Preclinical Activities in U.S. 


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Table 41 Cages Market, By Geography, 2013 2018 ($Million) 

Table 42 Bedding Market, By Geography, 2013 2018 ($Million) 

Table 43 Feed Market, By Geography, 2013 2018 ($Million) 

Table 44 Other Care Products Market, By Geography, 2013 2018 ($Million) 

Table 45 Global Mice Model Market, $Million (2013 -2018) 

Table 46 Nih Funding For Projects Related to Animal Models 

Table 47 Associations Directly Related to The Animal Model Market With Event 

Dates 

Table 48 Associations indirectly Related to The Animal Model Market With Event 

Dates 

Table 49 Distribution of Products and Projects By Phase (December 2011) 

Table 50 North America : Mice Model Market, $Million (2013 -2018) 

Table 51 North America : Market, By Type, $Million (2013 -2018) 

Table 52 North America : Market, By Technology, $Million (2013 -2018) 

Table 53 North America : Market, By Disease, $Million (2013 -2018) 

Table 54 North America : Market, By Service, $Million (2013 -2018) 

Table 55 North America : Mice Care Products Market, By Segment, $Million (2013 

-2018) 

Table 56 Biosimilars Pipeline - European Region -2011 

Table 57 Biosimilars Under Review By Ema -2013 


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Table 58 Events Conducted By Animal Care Associations to Promote The Ethical 

Use of Mice 

Table 59 EU-Funded Projects For Rare Diseases That Made Use of Mice Models 

Table 60 Europe: Mice Model Market, $Million (2013 -2018) 

Table 61 Europe: Market, By Type, $Million (2013 -2018) 

Table 62 Europe: Market, By Technology, $Million (2013 -2018) 

Table 63 Europe: Market, By Disease, $Million (2013 -2018) 

Table 64 Europe: Market, By Service, $Million (2013 -2018) 

Table 65 Europe: Mice Care Products Market, By Segment, $Million (2013 -2018) 

Table 66 AAALAC - Accredited Companies/institutes/Organizations/Universities, 

By Geography 

Table 67 Number of Guidelines/Associations For Regulatory Care of Animals, By 

Geography 

Table 68 Significant Funding Activities in Translational Research in Singapore 

Table 69 Global Researcher Views of Leading Countries in R&D By 

Research/Technology Area 

Table 70 R & D Trend in india 

Table 71 Research Partnerships With Japan 

Table 72 Research Projects Conducted At The Universiti Putra Malaysia 

Table 73 Asia: Mice Model Market, $Million (2013 -2018) 

Table 74 Asia: Market, By Type, $Million (2013 -2018) 


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Table 75 Asia: Market, By Technology, $Million (2013 -2018) 

Table 76 Asia: Market, By Disease, $Million (2013 -2018) 

Table 77 Asia: Market, By Service, $Million (2013 -2018) 

Table 78 Asia: Mice Care Products Market, By Segment, $Million (2013 -2018) 

Table 79 List of institutes Partnered Or Affiliated With The Australian Phenomics 

Network 

Table 80 ROW: Mice Model Market, $Million (2013 -2018) 

Table 81 ROW: Market, By Type, $Million (2013 -2018) 

Table 82 ROW: Market, By Technology, $Million (2013 -2018) 

Table 83 ROW: Market, By Disease, $Million (2013 -2018) 

Table 84 ROW: Market, By Service, $Million (2013 -2018) 

Table 85 ROW: Mice Care Products Market, By Segment, $Million (2013 -2018) 

Table 86 Agreements, Partnerships, Collaborations, and Joint Ventures (2010 

2013) 

Table 87 Licensing (20102013) 

Table 88 Grants and Funds (2010 2013) 

Table 89 Marketing and Promotion (2010 2013) 

Table 90 Expansions (2010 2013) 

Table 91 Patents (2010 2013) 

Table 92 New Product Launches (2010 2013) 


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Table 93 Others (2010 2013) 

Table 94 Charles River Laboratories, Inc.: Products 

Table 95 Charles River Laboratories, Inc.: Services 

Table 96 Covance, Inc.: Services 

Table 97 Covance, Inc.: Strategy 

Table 98 Genoway S.A.: Products 

Table 99 Genoway S.A.: Services 

Table 100 Genoway S 

List of Figures 

Figure 1 Market Segmentation 

Figure 2 Key Stakeholders 

Figure 3 Research Methodology- Market Size Estimation 

Figure 4 Research Methodology- Market Sizing 

Figure 5 Research Methodology- Competitive Assessment 

Figure 6 Research Methodology- Data Triangulation 

Figure 7 Research Methodology- Secondary Research Procedure 

Figure 8 Global Mice Model Market, By Type, 2013 ($Million) 

Figure 9 Global Market, By Services, 2013 ($Million) 


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Figure 10 Global Market, By Geography, 2013 ($Million) 

Figure 11 Market Share, By Company (in Terms of $Value), 2013 

Figure 12 Competitive Positioning, By Company (2010 2013) 

Figure 13 Mice Model Market (Inclusive of Models and Services, Based On Value, 

2012) 

Figure 14 Mice Model Market Segmentation, By Type 

Figure 15 Inbred and Knockout Mice Model Market, $Million (2013 2018) 

Figure 16 Mice Model Market Segmentation, By Technology 103 

Figure 17 Microinjection and Embryonic Stem Cell Based Mice Model Market, 

$Million (2013 2018) 

Figure 18 Mice Model Market, By Disease 

Figure 19 Oncology and Immunology and Inflammation Mice Model Market, 2013 


Figure 20 Mice Model Market Segmentation, By Service 

Figure 21 Inbred and Knockout Mice Model Market, $Million (2013 - 2018) 

Figure 22 Comparison of Global Mice Model Market By Services, By Geography 

(For The Year 2013 and 2018) 

Figure 23 Mice Care Products Market, By Segment 

Figure 24 Cages and Feed Market, $Million (2013 - 2018) 

Figure 25 Comparison of Global Mice Care Products Market, By Geography (For 

The Year 2013 and 2018) 


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Figure 26 Tapped/Matured and Untapped/Potential Markets 

Figure 27 Mice Model Market, By Geography 

Figure 28 Mice Model Market Geographic Analysis 

Figure 29 Scientific R&D Spending, By Country 

Figure 30 Competitive Developments Mapping (top Five Players For Each Key 

Growth Strategy) 

Figure 31 Share of Key Strategies (2010 2013 

Figure 32 Most Active Companies (2010 2013) 

Figure 33 Share of Agreements, Partnerships, Collaborations, and Joint Ventures 

(2010 2013) 

Figure 34 Share of Licensing (20102013) 

Figure 35 Share of Grants and Funds (2010 2013) 

Figure 36 Share of Marketing and Promotion (2010 2013) 

Figure 37 Share of Expansions (2010 2013) 

Figure 38 Share of Patents (2010 2013) 

Figure 39 Share of New Product Launches (2010 2013) 

Figure 40 Share of Others (2010 2013) 

Figure 41 Ablexis Llc : Geographic Presence 

Figure 42 Ablexis Llc : Strategy 

Figure 43 Charles River Laboratories, Inc.: Geographic Presence 


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Figure 44 Charles River Laboratories, Inc.: total Revenue, 2010 2012 ($Million ) 

Figure 45 Charles River Laboratories, Inc.: total Revenue, By Segment, 2010 2012 

($Million ) 

Figure 46 Charles River Laboratories, Inc.: Total Revenue, By Geography, 2010 

2012 ($Million ) 

Figure 47 Covance, Inc.: Geographic Presence 

Figure 48 Covance, Inc.: Total Revenue, 2010 2012 ($Million ) 

Figure 49 Covance, Inc.: Total Revenue, By Segment, 2010 2012 ($Million ) 

Figure 50 Covance, Inc.: Total Revenue, By Geography, 2010 2012 ($Million ) 

Figure 51 Crescendo Biologics: Geographic Presence 

Figure 52 Crescendo Biologics: Strategy 

Figure 53 Deltage N, Inc.: Geographic Presence 

Figure 54 Deltagen, Inc.: Total Revenue, 2010 2012 ($Million ) 

Figure 55 Deltage N, Inc.: Strategy 

Figure 56 Genoway S.A.: Geographic Presence 

Figure 57 Genoway S.A.: Total Revenue, 2010 2012 ($Million ) 

Figure 58 Genoway S.A.: Total Revenue, By Geography, 2010 2012 ($Million ) 

Figure 59 Genoway S.A.: Strategy 

Figure 60 Harbour Antibodies Bv : Geographic Presence 

Figure 61 Harbour Antibodies Bv : Strategy 


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Figure 62 Harlan Laboratories, Inc. : Geographic Presence 

Figure 63 Harlan Laboratories, Inc. : Strategy 

Figure 64 Immunogenes Ag : Geographic Presence 

Figure 65 Immunogenes Ag : Strategy 

Figure 66 Ingenious Targeting Laboratory : Geographic Presence 

Figure 67 Ingenious Targeting Laboratory : Stratgey 

Figure 68 Lexicon Pharmaceuticals : Geographic Presence 

Figure 69 Lexicon Pharmaceuticals : Total Revenue, 2010 2012 ($Million ) 

Figure 70 Lexicon Pharmaceuticals : Total Revenue, By Segment, 2010 2012 

($Million ) 

Figure 71 Lexicon Pharmaceuticals : Strategy 

Figure 72 Mirimus : Geographic Presence 

Figure 73 Mirimus : Strategy 

Figure 74 Sage Labs : Geographic Presence 

Figure 75 Sage Labs : Strategy 

Figure 76 Taconic Farms : Geographic Presence 

Figure 77 Taconic Farms : Strategy 

Figure 78 The Jackson Laboratory : Geographic Presence 

Figure 79 The Jackson Laboratory : Total Revenue, 2010 2012 ($Million ) 


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Figure 80 The Jackson Laboratory : Total Revenue, By Segment, 2010 2012 

($Million ) 

Figure 81 The Jackson Laboratory : Strategy 

Figure 82 Immunodeficient and Humanized Mouse Model Development Timeline 

Figure 83 Transgenic, Inc. : Geographic Presence 

Figure 84 Transgenic, Inc. : Strategy 

Figure 85 Colony Maintenance Types and Levels 


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JSB Market Research: Mice Model Market - by Type, Technology, Disease, Service & Care Products- Forecasts to 2018

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