DRUG CRITICAL CARE INTRAVENOUS MEDICATIONS
DRUG CRITICAL CARE INTRAVENOUS MEDICATIONS
DRUG CRITICAL CARE INTRAVENOUS MEDICATIONS
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<strong>DRUG</strong> <strong>CRITICAL</strong> <strong>CARE</strong> <strong>INTRAVENOUS</strong> <strong>MEDICATIONS</strong><br />
<strong>DRUG</strong> CONCENTRATION UNIT OF MEASUREMENT <strong>DRUG</strong><br />
CLASSIFICATION<br />
Amiodarone<br />
Bumex<br />
(Bumetanide)<br />
Cardizem (Diltiazem)<br />
450mg / 250ml<br />
D5W only<br />
Can not mix in NS<br />
10mg / 100ml<br />
Can mix in NS and D5W<br />
125mg / 125ml<br />
Can mix in NS and D5W<br />
Continuous Infusion – mg/minute<br />
Common dose: 1mg / min for 6 hrs,<br />
then 0.5 mg /min infusion<br />
IV Bolus Dose – mg<br />
Dose: 0.5 – 1 mg slow IVP over 1-2 min<br />
OR<br />
Continuous Infusion – mg/hour<br />
Usual Dose: 1 mg/hr or (MD preference)<br />
Continuous Infusion – mg/hour<br />
Dose: 5 – 15 mg/ hr<br />
Titrate 5 mg/hr increments to desired effect<br />
Antiarrhythmic<br />
Loop Diuretic<br />
Calcium<br />
Channel Blocker<br />
Cardene<br />
(Nicardipine)<br />
25mg / 250ml<br />
Can mix in NS and D5W<br />
Continuous Infusion – mg/hour<br />
Dose: 2.5 – 15 mg / hour<br />
Titrate 2.5 mg/hr increments Q 15 minutes<br />
Rotate IV infusion site Q 12 hr if<br />
administered via peripheral vein<br />
Calcium<br />
Channel Blocker<br />
Cisatracurium<br />
(Nimbex)<br />
Corlopam<br />
(Fenoldopam)<br />
200mg / 200ml<br />
Can mix in NS and D5W<br />
20mg/500ml<br />
Can mix in NS and D5W<br />
Continuous Infusion – mcg/kg/min<br />
May give IV loading dose: 0.1 mg/kg Usual<br />
Range: 1 – 10 mcg/kg/min<br />
Titrate 2 mcg/kg/min increments<br />
Continuous Infusion – mcg/kg/minute Dose:<br />
Initial 0.1 mcg/kg/min<br />
Titrate 0.05 – 0.2 mcg/kg/min increments Avg.<br />
rate = 0.25 – 0.5 mcg/kg/min<br />
Nondepolarizing<br />
Neuromuscular<br />
Blocker<br />
(Paralytic)<br />
Vasodilator<br />
Dobutamine<br />
Dopamine<br />
Epinephrine<br />
Fentanyl<br />
Furosemide<br />
(Lasix)<br />
500mg /250ml (Standard)<br />
Can mix in NS and D5W<br />
400mg /250ml (Standard)<br />
Can mix in NS and D5W<br />
5mg /250ml (Standard)<br />
Can mix in NS and D5W<br />
1mg /100ml NS (Standard)<br />
Can mix in D5W<br />
100mg / 100ml<br />
or<br />
200mg / 100ml<br />
Can mix in NS and D5W<br />
Continuous Infusion – mcg/kg/minute Dose:<br />
2 – 20 mcg/kg/min Vasopressor<br />
Continuous Infusion – mcg/kg/minute Dose:<br />
2 – 20 mcg/kg/min Vasopressor<br />
Continuous Infusion<br />
mcg/kg/minute --OR--mcg/minute<br />
Usual Range: 1 – 10 mcg/min<br />
Continuous Infusion – mcg/hour<br />
Usual Range: 50 – 300 mcg/hr<br />
Titrate 25 mcg/hr increments<br />
IV Bolus Dose – mg<br />
Dose: 20 -40 mg sl ow IVP over 1 -2 min<br />
OR<br />
Continuous Infusion – mg/hr<br />
Usual Dose: 10 -20 mg/hr<br />
or (MD preference)<br />
Vasopressor/<br />
Cardiac<br />
Stimulant<br />
Narcotic<br />
Analgesic<br />
Loop Diuretic
<strong>DRUG</strong> <strong>CRITICAL</strong> <strong>CARE</strong> <strong>INTRAVENOUS</strong> <strong>MEDICATIONS</strong><br />
<strong>DRUG</strong> CONCENTRATION UNIT OF MEASUREMENT <strong>DRUG</strong><br />
CLASSIFICATION<br />
Heparin<br />
Inocor<br />
(Inamrinone)<br />
Insulin<br />
Levophed (Norepinephrine)<br />
Lidocaine<br />
25,000 units / 250ml<br />
Can mix in NS and D5W<br />
500mg/100ml NS only, or<br />
250mg/50ml NS only Can<br />
not mix in D5W<br />
100 units /100ml NS only<br />
Can not mix in D5W<br />
4mg / 250ml (Standard)<br />
Can Mix in NS and D5W<br />
2 grams / 250ml<br />
Can mix in NS and D5W<br />
Continuous Infusion – units/hour<br />
Dose: Weight-based --OR--PTT-based<br />
Anticoagulant<br />
Continuous Infusion – mcg/kg/minute Dose:<br />
5 – 10 mcg/kg/min Positive Inotrope and<br />
Vasodilator<br />
Continuous Infusion – units/hour<br />
Dose: Based upon blood glucose level<br />
Continuous Infusion<br />
mcg/kg/minute – OR – mcg/minute<br />
Usual Range: 8 – 16 mcg/min<br />
Continuous Infusion – mg/minute<br />
Usual Range: 1 – 4 mg/min<br />
1mg/min=7.5 ml/hr, 3 mg/min = 22.5 ml/hr<br />
2 mg/min = 15 ml/hr, 4 mg = 30 ml/hr<br />
Hormone<br />
Antidiabetic Agent<br />
Vasopressor<br />
Antiarrhythmic<br />
Midazolam<br />
(Versed)<br />
Natrecor (Nesiritide)<br />
Neosynephrine<br />
(Phenylephrine)<br />
Nipride<br />
(Nitroprusside)<br />
Nitroglycerin<br />
Primacor<br />
(Milrinone)<br />
Pronestyl<br />
Vasopressin<br />
125mg / 125 ml<br />
Can mix in NS and D5W<br />
1.5mg / 250ml = (6 mcg/ml)<br />
Can mix in NS and D5W<br />
10mg / 250ml (Standard)<br />
Can mix in NS and D5W<br />
50mg / 250ml D5W only, or<br />
100mg / 250ml D5W only<br />
Can not mix in NS<br />
25mg / 250ml (Standard)<br />
Can mix in NS and D5W<br />
50mg / 250ml<br />
Can mix in NS and D5W<br />
2 grams / 250ml<br />
Can mix in NS and D5W<br />
20 units / 100ml (Standard)<br />
Can mix in NS and D5W<br />
Continuous Infusion – mg/hour<br />
Usual Range: 1 – 10 mg/hr<br />
Titrate 1 mg/hr increments<br />
IV bolus: 2 mcg/kg over 60 seconds<br />
Continuous Infusion: 0.01 mcg/kg/min<br />
D5W Continuous Infusion – mcg/minute<br />
Usual Range: 10 – 180 mcg/min<br />
Continuous Infusion – mcg/kg/minute Dose:<br />
0.3 –4 mcg/kg/min<br />
Titrate 0.5 mcg/kg/min increments<br />
Maximum = 10 mcg/kg/min<br />
Continuous Infusion – mcg/minute<br />
Usual Range: 1 – 200 mcg/min<br />
Continuous Infusion – mcg/kg/minute Usual<br />
Range: 0.375 – 0.75 mcg/kg/min<br />
Benzodiazepine<br />
(Sedative)<br />
B-type Natriuretic<br />
Peptide<br />
(Decompensated CHF)<br />
Vasopressor<br />
Vasodilator<br />
Vasodilator<br />
Positive Inotrope and<br />
Vasodilator<br />
Continuous Infusion – mg/minute<br />
Usual Range: 1 – 4 mg / min<br />
1mg/min =7.5 ml/hr, 3 mg/min =22.5 ml/hr,<br />
2 mg/min = 15 ml/hr, 4 mg = 30 ml/hr<br />
Antiarrhythmic<br />
Continuous Infusion – units/minute Range:<br />
0.01 – 0.1 units/min<br />
Usual Dose: 0.04 units/min fixed dose<br />
OR<br />
units/hour Usual Dose: 0.2 -0.9 units/hr<br />
Vasopressor<br />
(For Septic Shock)<br />
created by K Cooper and C. Watson - updated 2007
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