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Fascination - Science & Technology Facilities Council

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Front cover image: Student at Big Bang Fair 2011<br />

If you would like to register to receive <strong>Fascination</strong> automatically<br />

please visit http://www.stfc.ac.uk/fascination<br />

ISSUE 6 - May 2011<br />

News from the<br />

<strong>Science</strong> and <strong>Technology</strong><br />

<strong>Facilities</strong> <strong>Council</strong><br />

Exploring & Understanding <strong>Science</strong><br />

CONTENTS<br />

World’s biggest ever<br />

telescope<br />

Basque President marks<br />

success of international<br />

collaboration at ISIS<br />

Real time race<br />

I-TAC tenants secure<br />

£270,000 of funding<br />

National <strong>Science</strong> and<br />

Engineering Week goes off<br />

with a bang<br />

Access all areas,<br />

Backstage <strong>Science</strong>


New project will promote equality<br />

and diversity in HE research careers<br />

A new project ‘Every researcher counts’ led by Vitae and<br />

commissioned by the Higher Education Funding <strong>Council</strong> for<br />

England (HEFCE) is set to improve equality and diversity for<br />

research staff within the HE sector. Many of the challenges<br />

relating to equality and diversity are systemic within the<br />

HE sector, particularly for research staff. These can create<br />

a difficult environment for researchers, but particularly<br />

disadvantages some groups including women, disabled and<br />

black and minority ethnic researchers.<br />

The project is aiming to develop a network of at least<br />

50 individuals to act as ‘equality and diversity champions’<br />

from over 50 different HEIs across the UK. Vitae is currently<br />

seeking nominations from equality and diversity specialists,<br />

widening participation staff, Human Resources staff,<br />

academics, HEI senior managers or principal investigators<br />

(PIs). Champions will be expected to raise awareness of the<br />

researcher equality and diversity agenda within HEIs, use<br />

and distribute resources to PIs and staff developers, attend<br />

regional ‘train-the-trainer’ events, and provide feedback to<br />

the project team.<br />

The project is an important part of the HEFCE<br />

implementation strategy for the Concordat to Support the<br />

Career Development of Researchers.<br />

More information about the ‘Every researcher counts’,<br />

its wider objectives and outcomes is available on the Vitae<br />

website www.vitae.ac.uk For ECU guidance to HEIs regarding<br />

equality and diversity please visit: www.ecu.ac.uk<br />

The first science paper from the<br />

Research Complex at Harwell<br />

Research by scientists in the Laser for <strong>Science</strong> Facility, based at<br />

the Research Complex at Harwell (RcaH), and colleagues at the<br />

University of Bristol has shown how the energy generated by<br />

chemical reactions in solution is dissipated to the environment in<br />

less than a billionth of a second.<br />

Using the unique capabilities of STFC’s ULTRA laser system,<br />

scientists from the University of Bristol have been able to watch<br />

a chemical reaction happening in solution with more detail than<br />

ever before. This could lead to improved drug design for medical<br />

therapies and catalysts for industrial processing, and pave the<br />

way for further applications in bio- and atmospheric chemistry.<br />

The superfast ULTRA laser system was able to monitor the<br />

transfer of energy from the reaction product to the surrounding<br />

solvent by following changes in chemical bonds much faster than<br />

was possible previously. The research is featured on the cover of<br />

the journal <strong>Science</strong>.<br />

<strong>Science</strong> Paper. http://www.sciencemag.org/<br />

content/331/6023.cover-expansion<br />

2


Getting ready for the world’s<br />

biggest ever telescope<br />

Plans for the world’s biggest telescope - the<br />

Square Kilometre Array (SKA) - have advanced<br />

significantly with a decision to locate the<br />

project office at Jodrell Bank Observatory near<br />

Manchester.<br />

The SKA is a €1.5 billion global science project to build the<br />

world’s largest and most sensitive radio telescope. The SKA<br />

will be capable of answering some of the most fundamental<br />

questions about the Universe.<br />

STFC’s Professor John Womersley, chair of the Founding<br />

Board, said: “Given the current economic environment, it<br />

is reassuring that so many partners have recognised the<br />

importance of supporting the SKA.<br />

Our partners have taken this step not only because of the<br />

inspirational nature of the discoveries that the SKA will make,<br />

but also because of the economic benefits that international<br />

megascience projects can bring to participating countries.”<br />

The SKA project will drive technology development in<br />

antennas, signal transport, signal processing, and software<br />

and computing. Spin off innovations in these areas will benefit<br />

other systems that process large volumes of data. The design,<br />

construction and operation of the SKA has the potential to<br />

impact skills development in science, engineering and in<br />

associated industries, not only in the host countries but in all<br />

project partners.<br />

Artist’s impression of the SKA dishes<br />

(Credit: SPDO / TDP / DRAO / Swinburne<br />

Astronomy Productions)<br />

£11M investment destined<br />

to make air travel safer<br />

Universities and <strong>Science</strong> Minister<br />

David Willetts announced £11M<br />

funding to build a new testing<br />

facility that will make electronics<br />

systems less susceptible to the<br />

potentially catastrophic effects<br />

of cosmic neutrons, during a visit<br />

to STFC’s Rutherford Appleton<br />

Laboratory.<br />

Funding from the Large <strong>Facilities</strong><br />

Capital Fund will be used to build<br />

a new beamline on the world<br />

leading ISIS neutron source.<br />

Called ‘Chipir’, the beamline will<br />

be used to simulate the effects<br />

of cosmic radiation which can<br />

cause the failure of microchips<br />

in sensitive electronics systems.<br />

Problems can vary from wiping a<br />

device’s memory to the complete<br />

destruction of the electronics - a<br />

serious issue at altitude. In a single<br />

hour, ISIS will be able to replicate<br />

the effects of 100 years of flying<br />

time.<br />

David Willetts, Minister<br />

for <strong>Science</strong> at STFC’s ISIS<br />

facility<br />

3


<strong>Technology</strong> Breakthrough<br />

Back in issue 2 we reported on the EMMA accelerator - A brand<br />

new technology that promises a range of applications from<br />

treating cancer to powering safer nuclear reactors. EMMA is<br />

located at STFC’s Daresbury Laboratory. EMMA is a proof of<br />

principle prototype for a brand new type of particle accelerator,<br />

designed by an international team of scientists, including a<br />

number of the UK’s top universities and institutes. A major<br />

part of the BASROC CONFORM project, EMMA is funded by the<br />

Research <strong>Council</strong>s UK (RCUK) Basic <strong>Technology</strong> programme.<br />

EMMA has now achieved its most significant milestone<br />

yet. For the first time, an electron beam was steered around<br />

the circumference of EMMA’s ring and then successfully<br />

accelerated to 18 MeV. This momentous milestone, and a world<br />

first, not only confirms that the design of the most technically<br />

demanding aspects of EMMA is sound, it also demonstrates the<br />

feasibility of EMMA’s technology, which now paves the way for<br />

the construction of a whole new generation of more powerful,<br />

yet more compact and economical accelerators.<br />

http://www.conform.ac.uk<br />

ALMA up date<br />

On 30 March the ALMA Observatory, an array of millimetre<br />

wave telescopes being constructed in the Atacama Desert of<br />

Chile, issued its first Call for Proposals.<br />

ALMA now has 16 of its planned 50 antennas available<br />

and is ready for early scientific exploitation. As the world’s<br />

largest millimetre wave interferometer ALMA is a very powerful<br />

and complex instrument; to make it as easy as possible for<br />

astronomers to plan and make their observations, a special<br />

ALMA Observing Tool has been developed by a team led by<br />

Dr Alan Bridger of the UK Astronomy <strong>Technology</strong> Centre (UK<br />

ATC). The software, which is the Astronomers’ main interface<br />

to ALMA, has been in development since 2002 and is already<br />

in use for commissioning of the facility. The tool is the first<br />

of its kind for an interferometer and its 500,000 lines of code<br />

were written by a team including members from Edinburgh and<br />

Mitako (Tokyo), the team interacts with other ALMA developers<br />

in 12 sites across the world.<br />

The UK ATC software group is part of a large collaboration,<br />

which includes the European Southern Observatory and the<br />

National Astronomical Observatory of Japan. Alan and many<br />

of his team have years of experience developing integrated<br />

observation preparation, execution and analysis software,<br />

examples of which were deployed on the JCMT and UKIRT<br />

telescopes in Hawaii during 1998 and 1999. Packages like<br />

this make planning and executing observations very efficient<br />

and flexible, so it is possible to match observing plans to<br />

atmospheric conditions and maximise the scientific return from<br />

these powerful facilities.<br />

For more information visit<br />

www.almaobservatory.org<br />

www.ukatc.ac.uk<br />

The Atacama Large Millimeter<br />

Array (ALMA)<br />

4


Basque President marks success of<br />

international collaboration at ISIS<br />

Patxi Lopez, President of the Basque Country and Dr Andrew Taylor, ISIS Director,<br />

with the steel vacuum tank manufactured in the Basque Country for installation at<br />

the ISIS Neutron Source.<br />

The scientific and technical<br />

collaboration between STFC’s<br />

ISIS neutron source and the<br />

Basque Country has been<br />

celebrated during a visit by<br />

the region’s President Patxi<br />

Lopez.<br />

International<br />

collaborations have enabled<br />

ISIS to continually push the<br />

boundaries of accelerator<br />

technology and neutron<br />

instrumentation to deliver<br />

innovative and highimpact<br />

science. Exchanging<br />

technological expertise has<br />

enabled Basque companies<br />

to manufacture high-tech<br />

equipment for ISIS and other<br />

similar projects.<br />

Dr Andrew Taylor, Director,<br />

ISIS, said: “For more than<br />

twenty years, ISIS has been<br />

a world leader, a position<br />

we maintain because of<br />

the excellence of our staff<br />

and of our international<br />

partnerships.”<br />

High temperature<br />

optical sensors<br />

Wave-Phire Sensor<br />

STFC’s spin out company Oxsensis is developing fibre optical<br />

sensors for hostile environments, including extremely high<br />

temperatures and pressures. They will be used in ultra high<br />

temperature situations such as gas turbines for power<br />

generation, aero-engines industrial processes and other<br />

hostile environments such as poisonous gas detection and<br />

petrochemical processes.<br />

This is contributing to the development of a range of<br />

internal combustion engines including reciprocating engines<br />

and gas turbines.<br />

Internal combustion engine development continues to<br />

address a number of challenges including, for example, the<br />

management of stable lean burn combustion at temperatures<br />

up to 1000˚C across wide operating ranges, and the use of<br />

varying fuel compositions. The drive to reduce fuel burn is<br />

relentless and early thermodynamic wins are now giving<br />

way to harder and more complex steps which are needed to<br />

ensure continued progress. Sophisticated control strategies<br />

are emerging, which require reliable and ‘actionable’<br />

information in order to succeed.<br />

Initially sensors were trialled in relevant test rigs<br />

constructed within Oxsensis laboratory facilities. Such<br />

rigs are designed to recreate aspects of the harsh engine<br />

environment such as the high temperatures, pressures,<br />

vibration levels and acoustic effects, however, none can truly<br />

combine all of these aspects to fully recreate the real-life<br />

environment.<br />

After completion of these initial laboratory based<br />

demonstrations, the systems were deployed in full engine<br />

operation for land-based tests on smaller aero engines. A<br />

helicopter engine offered the first test berth, followed by a<br />

turbojet engine and other land-based aero engine tests, some<br />

of which are ongoing. A total of 50,000 combined running<br />

hours have now been achieved with five sensors at the<br />

Didcot B Power station.<br />

Oxsensis is extending its R&D experience into a number<br />

of reciprocating engine test environments during 2011. There<br />

are two main engine areas for evaluation; in-cylinder and<br />

exhaust manifold locations.<br />

Oxsensis will run dynamic pressure sensors in a<br />

commercial development engine, in a 1000°C location,<br />

upstream of a turbocharger. Oxsensis will also trial incylinder<br />

sensors on another research automotive test bed.<br />

The next stage will involve work with a number of<br />

research groups to provide them with the opportunity<br />

to evaluate multi-parameter sensing systems, first in the<br />

laboratory, and then in rigs and also engine tests.<br />

http://www.oxsensis.com/<br />

5


Real time race<br />

not just playing games<br />

Based at the Daresbury Innovation Centre Real Time Race<br />

(RTR) develops three dimensional immersive video graphics,<br />

initially for the computer game market. If you look on its<br />

website www.rtr.co/ you will see how they produce a<br />

perfect video representation of the Lotus Test Track. This<br />

system, called iflex, has two advantages, it is significantly<br />

more efficient than using CGI, taking a fraction of the time of<br />

conventional means and it produces quality images with TV<br />

like reality.<br />

The key to the patented system is sophisticated software<br />

that combines military grade GPS, high resolution laser range<br />

finding and 3D video. It is so sensitive that it can detect<br />

minor changes in the road surface, such as white marking<br />

lines.<br />

Matching the iflex images with a physics engine enables<br />

you to design the capabilities of a virtual physics engine<br />

vehicle, be it a racing car, motorcycle or off road vehicle to<br />

replicate exactly the behaviour that you want.<br />

This enables car manufacturers, advertising agencies<br />

and race track operators to have effective high quality<br />

simulations. Furthermore it can provide a realistic driver<br />

training aid for emergency services.<br />

Of course the applications of this system are not restricted<br />

to racing simulations. The accuracy of the system makes<br />

it ideal for sophisticated engineering analysis. Caterpillar,<br />

the earth moving equipment manufacturer, uses the iflex<br />

system to accurately map quarry floors, including the<br />

surface, potholes and rocks and then match this with 3D<br />

videos of the suspension and tyre movements to get a better<br />

understanding of the impact of different environments on<br />

their vehicles endurance and performance.<br />

The latest addition to RTR’s range is itherm, merging iflex<br />

with a 3D thermal imaging system that enables mass surveys<br />

of cities, industrial plant, road surfaces etc<br />

www.rtr.co/<br />

6


OCF enCORE service uses STFC<br />

server cluster to power Lola Cars<br />

The use of server clusters or ‘supercomputers’ to aid research<br />

and development is not new. However, accessing their<br />

processing power as a service from a third-party supplier is<br />

certainly an innovation.<br />

In December 2010 STFC signed a unique agreement with OCF<br />

plc to make use of spare processing power from its own IBM<br />

iDataPlex server cluster. OCF will make that processing power<br />

available to UK businesses of any service through its enCORE<br />

service. Naturally OCF works very closely with STFC (including<br />

becoming a tenant at the Daresbury <strong>Science</strong> and Innovation<br />

Campus).<br />

Phil Tiller, Senior Aerodynamicist at Lola Cars, a racing car<br />

engineering company, has been successfully using enCORE<br />

and STFC’s spare power for around four weeks. He is testing<br />

Computation Fluid Dynamics (CFD) research and development<br />

cases.<br />

Phil comments: “We have been able to use enCORE to reduce<br />

processing time for our test cases to just five hours, down from<br />

up to two days. It means we can get information out to the<br />

engineers on the track in advance of weekend racing.”<br />

He continues: “We always want a bigger computer, but the<br />

business does not have infinite resources. Using enCORE is a like a<br />

pay-as-you-go mobile, you can spend as you use it, when you use<br />

it and not at other times. It becomes a manageable running cost.”<br />

enCORE has been successfully tested by a range of companies<br />

since December, including Lola Cars, and is now available to any<br />

UK business.<br />

www.ocf.co.uk<br />

Dyson Racing Lola-Mazda<br />

LMP at Long Beach<br />

(Credit Lola/Regis Lefebure)<br />

Using X-rays to fight tooth decay<br />

Tooth decay is very common, and affects people of all ages.<br />

The problem is caused by sticky deposits called plaque that<br />

collect, most commonly around the gum line and the grooved<br />

surfaces of the teeth. So how could a team of researchers<br />

from the UK and Japan use the Diamond synchrotron, based<br />

at the Harwell Oxford Campus, and the Photon Factory in<br />

Tsukuba City, Japan, to solve the 3D structure of an enzyme<br />

that plays a key role in tooth decay<br />

caused by sugar?<br />

Tooth decay can occur when<br />

a biofilm, or dental plaque as it is<br />

more commonly known, is formed<br />

by a large and sticky glucose<br />

polymer called glucan. The glucan<br />

biofilm contains bacteria and food<br />

debris and forms on the surface<br />

of the tooth. As they grow, the<br />

bacteria secrete acids which break<br />

down the tooth’s hard enamel<br />

on the surface. The structural<br />

information published in the Journal<br />

of Molecular Biology provides a<br />

critical insight into how the enzyme<br />

‘GTF-SI’, a glucansucrase, forms<br />

glucan, the sticky biofilm substance.<br />

“With the use of the Diamond<br />

synchrotron and the Photon<br />

Factory we have been able to solve not only the structure<br />

of the enzyme alone but also its structure when bound to<br />

an existing inhibitor,” says Sohei Ito from the Laboratory of<br />

Food Protein Engineering at the University of Shizuoka in<br />

graphical abstract (of a glucansucrase enzyme from the dental caries<br />

pathogen Streptococcus mutans forming a biofilm, and the acids<br />

within) credit: Reprinted from the Journal of Molecular Biology, Vol<br />

408, Issue 2, Keisuke Ito et al. ‘Crystal Structure of Glucansucrase<br />

from the Dental Caries Pathogen Streptococcus mutans’. Pages 177-<br />

378, Copyright (2011), with permission from Elsevier.<br />

Japan, and lead researcher on the project. “Several inhibitors<br />

that prevent this type of enzyme forming glucan have<br />

been identified but to date there has been little structural<br />

information available. With the data we collected at Diamond<br />

and the Photon Factory, we now have a better understanding<br />

of how the enzyme functions and how it can be stopped. This<br />

structural information should be useful in the design of novel<br />

inhibitors that will prevent the<br />

biofilm formation by glucansucrases<br />

and reduce the risk of possible side<br />

effects such as hypoglycaemia.<br />

These novel inhibitors could be<br />

incorporated into toothpaste and<br />

mouthwash, making them more<br />

effective at preventing tooth<br />

decay.”<br />

The structural data collection<br />

at the Diamond synchrotron<br />

was carried out on the I02<br />

Macromolecular Crystallography<br />

(MX) experimental station. Principal<br />

Beamline Scientist, Professor<br />

Thomas Sorensen, says, “Knowing<br />

the 3D structure of the enzyme is<br />

like knowing the shape of a lock<br />

you need to find a key for – it makes<br />

it much easier to find the right key<br />

that will fit. In this case, the inhibitor acts like the key, fitting<br />

into the lock in just the right way so that it can do its job.”<br />

www.diamond.ac.uk, University of Shizuoka<br />

visit http://eng.u-shizuoka-ken.ac.jp/index.html<br />

7


I-TAC Tenants secure<br />

£270,000 of funding<br />

The Innovations <strong>Technology</strong> Access Centre (I-TAC) prides<br />

itself on supporting SME’s in the early stages of their business<br />

development by providing access to world class facilities,<br />

high specification equipment and STFC expertise. After its first<br />

year in operation, I-TAC has achieved significantly more than<br />

expected. Tenant companies have employed 12 new people,<br />

£270,000 of funding and investment has been secured by the<br />

tenants and over 200 people have been shown around I-TAC.<br />

Within I-TAC, tenants cover the areas of energy, healthcare<br />

and environment, in line with the government’s and STFC’s<br />

strategy for addressing solutions to these grand challenges. The<br />

running of the I-TAC Futures Challenge (detailed in <strong>Fascination</strong><br />

issue 5) allowed companies to win access to I-TAC’s facilities in<br />

these key target areas. The STFC Futures Programme was the<br />

support behind the competition.<br />

The Futures Programme was STFC’s response to ensuring<br />

that skills and technology originally developed to address<br />

fundamental research questions are harnessed effectively to<br />

provide solutions to the global challenges.<br />

Since they have been on site this is what just three of the<br />

companies have achieved;<br />

Butters Innovations Ltd has gained £195,000 in funding<br />

since being based in I-TAC. £25,000 came from achieving a<br />

Disruptive Innovation Award from a <strong>Technology</strong> Strategy Board<br />

(TSB) competition. This has enabled them to commission the<br />

Engineering <strong>Technology</strong> Centre on the Daresbury <strong>Science</strong> and<br />

Innovation Campus (DSIC) to co-develop the software, electronics<br />

and mechanical elements of their MoRoW II stroke patient<br />

rehabilitation device. A working electro-mechanical prototype<br />

will undergo clinical trials later this year. The same project gained<br />

Butters Innovation a £10,000 Strategic IP Audit grant from the<br />

UK Intellectual Property Office; they have also received £160,000<br />

from the NHS I4I programme. “It’s very exciting to work with<br />

such an experienced and talented team of hardware and software<br />

engineers. Working at I-TAC has enabled us to fill a gap in our<br />

own capabilities. We have also recently incorporated a new<br />

company called MoRoW Ltd who are helping us commercialise<br />

the device we are building. Working with the team at I-TAC<br />

has helped us apply for equity funding which will help us fully<br />

commercialise the project.” Butters Innovations Ltd project<br />

partners include University of Salford, Medilink North West and<br />

PDS Engineering.<br />

8<br />

TopCat Research Ltd aims to provide effective and cost<br />

conscious analytical products for the food, pharmaceutical and<br />

environmental markets with products based on immunoassay<br />

(ELISA) and DNA detection (PCR) platforms. Director, Anthony<br />

Cope, said “Bringing my business to I-TAC has enabled me to<br />

gain £50,000 from the NW Fund to achieve proof of concept.<br />

We’re developing a pregnancy testing technology that will be<br />

used to help breeding programmes for endangered animals -<br />

nothing like this exists at the moment. Being based at I-TAC was<br />

a huge positive when applying for funding. This type of support<br />

was not available anywhere else. I look forward to growing<br />

and developing my ideas and taking on new staff in the months<br />

ahead.”<br />

BiSN Technologies Ltd offers a range of services to help oil<br />

and gas operators in a variety of areas, from materials testing<br />

to research and development in microbiologically enhanced oil<br />

recovery. BiSN has recently gained £25,000 in funding from the<br />

<strong>Technology</strong> Strategy Board. Paul Carragher and Leo Richards said:<br />

“The equipment and facilities, both at Daresbury and throughout<br />

the STFC network, allow us to compete at a world leading level.<br />

The range of services we can now offer matches, and in most<br />

cases exceeds, what our competitors can offer. In addition, the<br />

STFC and campus network has already proved valuable, having<br />

linked us to academic and industrial contacts. “<br />

www.itac.stfc.ac.uk and www.stfc.ac.uk/Futures


National <strong>Science</strong> and<br />

Engineering Week<br />

goes off with a BANG<br />

Like many organisations STFC was<br />

heavily involved with events during<br />

and around National <strong>Science</strong> and<br />

Engineering week.<br />

With over 29,000 people attending<br />

The Big Bang 2011, one of the UK’s<br />

biggest science events for young<br />

people celebrating science, technology,<br />

engineering and mathematics, STFC were<br />

proud to send a team from ISIS. The<br />

team together with experts from Cella<br />

Energy (<strong>Fascination</strong> issue 5, STFC spin out<br />

company) had a stand on the theme of low<br />

carbon energy. The stand featured mini<br />

hydrogen-powered cars and an array of<br />

novel hydrogen storage material samples.<br />

For the scientists and engineers working<br />

on the stand, it was a rare opportunity to<br />

talk to children and young people about<br />

their work at ISIS: “I had an excellent<br />

time”, said Atahl Nathanson, a UCL PhD<br />

student working with ISIS on hydrogen<br />

storage. “It was an excellent opportunity<br />

to explain how hydrogen fuel cells work<br />

to a completely different audience. It was<br />

also a great chance to see what other<br />

organisations are up to!”<br />

“We all really<br />

enjoyed it and<br />

found the level<br />

about right - quite<br />

challenging but<br />

grounded in<br />

things that they<br />

were familiar<br />

with. It brought<br />

the subject alive<br />

for the students.<br />

Please add us to<br />

your mailing list!<br />

9


Pulling together<br />

to get top results<br />

How do you see inside something if it is too small to see even with the most<br />

powerful microscope? To look inside a molecule and see the arrangement<br />

of the atoms? Crystallography is one potential answer. Crystallography is a<br />

process which provides 3-dimensional information from proteins and helps<br />

provide basic understanding of biological processes on a molecular level.<br />

Crystallography is the method<br />

that gives you the best resolution .<br />

Out of the original seven beamlines<br />

at Diamond three were specifically<br />

for use with this process and<br />

now 5 dedicated instruments for<br />

macromolecular crystallography<br />

(MX) are operational. Microfocus MX<br />

beamline provides X-ray beams down<br />

to 5 microns allowing investigations<br />

of samples with dimensions of only<br />

a few micrometres, instead of a<br />

few tens of microns for standard<br />

experiments.<br />

A brand new set up at the Harwell<br />

Oxford Campus is expected to open<br />

up a whole new realm of possibilities<br />

in crystallography. For the first time<br />

micro-crystals can be captured and placed onto sample<br />

holders used on the Diamond MX beamlines in a very specific<br />

way through the use of laser tweezers – previously this has<br />

been a random selection process. For X-ray studies being able<br />

to select the bigger crystals can improve the resolution of the<br />

obtained protein structure significantly. Using laser tweezers<br />

makes the capture of specific sized crystals in the sample<br />

possible.<br />

Typical CPV crystal preparation.<br />

Average sample size is around 5 x 5 x 5 microns.<br />

A ‘spiders web’ has been designed<br />

by STFC’s Micro and Nanotechnology<br />

Centre (MNTC) to sit under the<br />

mesh that the identified crystals are<br />

placed on – this ensures that even<br />

smaller crystals can be captured.<br />

This means many more crystals can<br />

be examined – usually those samples<br />

would be lost because there was no<br />

system capable of analysing them<br />

so important information could<br />

have been lost. The overall time for<br />

capturing and analysing crystals will<br />

be drastically improved. It will be far<br />

more time effective than the random<br />

process. Previously you may have<br />

needed to go through as many as<br />

300 samples to collect results from the<br />

correct size of crystal now you can just collect the specific<br />

samples you need.<br />

The collaboration stretches right across the Harwell Oxford<br />

Campus . The facilities involved are Diamond, Central Laser<br />

Facility MNTC and the Research Complex at Harwell together<br />

with Zeiss Microimaging. Although not yet fully operational<br />

this collaboration will offer many benefits. Once the required<br />

modifications to the process have been made the plan will be<br />

to integrate this system into the Diamond proposal system.<br />

ESA TTN Showcase<br />

STFC Daresbury Laboratory,<br />

17 May<br />

including an introduction to STFC<br />

and UK ESA <strong>Technology</strong> transfer activities<br />

http://www.stfc.ac.uk/Business+and+Innovation/22067.aspx<br />

10


Daresbury’s first I-TAC<br />

tenant cleans up with<br />

supermarket giant<br />

Bug battling firm Byotrol, which researched and developed its<br />

revolutionary hygiene technology at STFC’s I-TAC, has worked with<br />

McBrides, Europe’s leading provider of Private Label Household products,<br />

to launch a ground-breaking cleaning spray for Tesco.<br />

Byotrol’s patented technology, which is used<br />

in wipes, sprays and mousses to combat the<br />

spread of viruses and superbugs, including<br />

MRSA, is the main bacteria-killing ingredient<br />

in Tesco’s own-brand multi-surface spray. In<br />

contrast to old technologies, Byotrol contains<br />

no alcohol or bleach so is gentler on skin and<br />

the environment and is significantly longer<br />

lasting than traditional but harsher cleaning<br />

products currently on the market.<br />

Manchester-based Byotrol relocated<br />

its entire R&D division from Germany to<br />

Daresbury’s I-TAC in 2009 to develop and<br />

enhance its patented technology.<br />

A-level students tell us what they think of<br />

this year’s Particle Physics Masterclasses<br />

Hundreds of A-level students went to STFC’s Daresbury and<br />

Rutherford Appleton Laboratories during National <strong>Science</strong><br />

and Engineering Week (11-20 March 2011) to take part in<br />

Particle Physics Masterclasses. The classes are designed to<br />

inspire students to pursue careers in science and fill key jobs<br />

in science, technology, engineering and mathematics.<br />

STFC Press Officer Lucy Stone went to speak to a few of the<br />

students at Rutherford Appleton Laboratory (RAL):<br />

Audio file of Lucy Stone’s interview with Masterclass students<br />

http://www.stfc.ac.uk/resources/mp/PPMFINALAUDIO.mp3<br />

The students at RAL learnt about contemporary research in<br />

particle physics. Their day<br />

included a visit to the ISIS<br />

neutron source or Diamond<br />

Light Source, two of the<br />

world’s leading centres<br />

for materials research,<br />

both driven by high-power<br />

particle accelerators. The<br />

event included talks by<br />

particle physicists from RAL<br />

and CERN, and a computerbased<br />

workshop using real<br />

data from the Large Hadron<br />

Collider.<br />

Students from schools across the North West joined scientists<br />

from the Cockcroft Institute (CI) at Daresbury Laboratory for the<br />

annual Particle Physics Masterclass. Building on the successes<br />

of previous years, and acknowledging the unique opportunities<br />

available in running a masterclass at a national laboratory, the<br />

CI outreach group obtained agreement from the Institute of<br />

Physics to shift the emphasis towards accelerator design and<br />

performance, thereby showcasing the technologies that facilitate<br />

particle physics experiments. This was essentially the first particle<br />

and accelerator physics masterclass.<br />

Some new activities were run this year, including an exercise<br />

to show how the basic design parameters for the Diamond Light<br />

Source were calculated from the target specifications, and a<br />

new and challenging exercise to study how an electron bunch<br />

is both compressed and rotated in space to maximise the peak<br />

current before it is used to drive the free-electron laser on the<br />

ALICE accelerator. These were backed by other tried-and-tested<br />

exercises to estimate the injector beam energy in ALICE using<br />

only some basic physics and a few simple measurements, plus<br />

particle physics simulations, and further supported by lectures<br />

on the quark model of<br />

particle physics and aspects<br />

of particle accelerator<br />

science.<br />

Scientists and engineers<br />

from RAL Space were also<br />

very busy engaging with<br />

over 1000 members of the<br />

public in science week:On<br />

11 and 12 March, families<br />

and members of the public<br />

received expert tuition<br />

on the stars in our night<br />

sky during activities organised as part of the Reading <strong>Science</strong><br />

Week. Barry Kellett, from RAL Space, explained the make-up of<br />

our Moon with a hands-on display of Moon rocks and meteorites,<br />

whilst Reading Astronomical Society were on hand to assist with<br />

stargazing.<br />

Several graduates from the robotics team took a robot<br />

challenge to the Changing Perspectives Festival at Bristol,<br />

organised by Bristol University; http://www.bristol.ac.uk/<br />

public-engagement/events/2011/37.html.<br />

11


Access all areas<br />

Backstage <strong>Science</strong><br />

<strong>Science</strong> is a subject that<br />

fascinates most of us. What<br />

makes our science so exciting,<br />

the study of materials, the<br />

solving of problems?<br />

Have you ever wanted to look<br />

inside a particle accelerator? Meet<br />

a plasma scientist? Here is your<br />

opportunity to take a peak inside<br />

STFC.<br />

Backstage <strong>Science</strong> is a small<br />

selection of videos about STFC. The<br />

footage includes interviews with<br />

some our scientists and a fantastic<br />

unparalleled opportunity to see<br />

behind the scenes at many of our<br />

facilities, most of which can’t easily be<br />

accessed.<br />

From fitting a new instrument on<br />

ISIS (set of super microscopes) to<br />

creating a vacuum better than on the<br />

Moon - STFC science and technology<br />

covers many areas.<br />

Take a look for yourself:<br />

http://www.youtube.com/<br />

Backstage<strong>Science</strong><br />

Royal Society pairing scheme:<br />

for MPs, civil servants and scientists<br />

The Royal Society is looking for scientists to take part in its pairing<br />

scheme for MPs, civil servants and scientists.<br />

The scheme starts in Autumn with the ‘Week in<br />

Westminster’: a programme of activities for the scientists<br />

including seminars, workshops, shadowing opportunities<br />

and a tour of Westminster.<br />

Applications are now open to scientists with an interest<br />

in science policy, a proven ability to communicate their<br />

research and at least three years of post-doctoral research<br />

experience.<br />

For more information, please visit: royalsociety.org/pairing-scheme<br />

Contacts<br />

<strong>Science</strong> and <strong>Technology</strong> <strong>Facilities</strong> <strong>Council</strong>,<br />

Polaris House, North Star Avenue, Swindon,<br />

SN2 1SZ<br />

Tel: +44 (0)1793 442000<br />

Fax: +44 (0)1793 442002<br />

Email: fascination@stfc.ac.uk web: www.stfc.ac.uk<br />

<strong>Fascination</strong> is produced six times a year.<br />

To subscribe please go to:<br />

http://www.stfc.ac.uk/stfcforms/NewsletterBooking.aspx<br />

Edited by Jane Binks.<br />

Designed by STFC Media Services. Printed by the Research<br />

<strong>Council</strong>’s Joint Reprographics Service.<br />

If you have comments on this publication, or suggestions for<br />

future editions please email fascination@stfc.ac.uk

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