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Human Anatomy, First Edition<br />

McKinley & O'Loughlin<br />

Chapter 5 Lecture Outline:<br />

<strong>Integumentary</strong> <strong>System</strong><br />

1<br />

2<br />

The Integument<br />

• The skin that covers your body.<br />

• Skin is also known as the cutaneous<br />

membrane.<br />

• <strong>Integumentary</strong> system consists of the<br />

skin and its derivatives—nails, hair,<br />

sweat glands, and sebaceous glands.<br />

5-3<br />

1


The Integument<br />

• Is the body’s largest organ.<br />

• Its surface is covered by an epithelium that protects<br />

underlying body layers.<br />

• The connective tissues contain blood vessels that<br />

provide nutrients and provide strength and resilience<br />

to the skin.<br />

• Smooth muscle controls both blood vessel diameter<br />

and hair position.<br />

• Neural tissue supports and monitors sensory<br />

receptors in the skin<br />

5-4<br />

2 Distinct Layers<br />

• A layer of stratified squamous<br />

epithelium called the epidermis.<br />

• A deeper layer of dense irregular<br />

connective tissue called the dermis.<br />

• deep to the dermis is a layer of areolar and<br />

adipose connective tissue called the<br />

subcutaneous layer, or hypodermis<br />

5-5<br />

6<br />

2


7<br />

Thick Skin<br />

• Thick epidermis is found on the palms<br />

of the hands, the soles of the feet, and<br />

corresponding surfaces of the fingers<br />

and toes.<br />

• All five epidermal strata occur in thick<br />

skin.<br />

5-8<br />

Thin Skin<br />

• Thin epidermis covers most of the body.<br />

• Lacks the stratum lucidum<br />

• Has only four specific layers.<br />

• Contains the following accessories: hair<br />

follicles, sebaceous glands, and sweat<br />

glands.<br />

5-9<br />

3


Functions of Skin<br />

• protection<br />

• prevention of water loss<br />

• temperature regulation<br />

• metabolic regulation<br />

• immune defense<br />

• sensory reception<br />

• excretion<br />

5-10<br />

Skin Color<br />

• Hemoglobin is an oxygen-binding protein<br />

present in red blood cells. Upon binding with<br />

oxygen, hemoglobin exhibits a bright red<br />

color.<br />

• Melanin is a pigment produced and stored in<br />

cells called melanocytes.<br />

• the two types of melanin occur in various yellow,<br />

reddish, tan, brown, and black shades<br />

• Carotene comes primarily from diet.<br />

5-11<br />

Friction Ridges<br />

• Found on the fingers, palms, soles, and toes.<br />

• Formed from large folds and valleys of both<br />

dermal and epidermal tissue.<br />

• Help us grasp objects, and they<br />

• Increase friction so that items do not slip<br />

easily from our hands.<br />

• Our feet do not slip on the floor when we<br />

walk.<br />

5-12<br />

4


Friction Ridges<br />

• Friction ridges can leave noticeable<br />

prints on touched surfaces.<br />

• Each individual has a unique pattern of<br />

friction ridges.<br />

• Fingerprints have become a valuable<br />

tool for law enforcement in identifying<br />

individuals.<br />

5-13<br />

Skin Markings<br />

• Nevus (mole)<br />

• Freckles<br />

• Hemangioma<br />

• capillary hemangiomas (“strawberrycolored<br />

birthmarks”)<br />

• cavernous hemangiomas (“port-wine<br />

stains”)<br />

5-14<br />

Layers of the Dermis<br />

• Composed of cells of the connective<br />

tissue proper and primarily of collagen<br />

fibers, although both elastic and<br />

reticular fibers are also present.<br />

• Other components of the dermis are<br />

blood vessels, sweat glands, sebaceous<br />

glands, hair follicles, nail roots, sensory<br />

nerve endings, and muscular tissue.<br />

5-15<br />

5


2 Major Regions of Dermis<br />

• Superficial papillary layer<br />

• Deeper reticular layer<br />

5-16<br />

Lines of Cleavage<br />

• Tension lines in the skin identify the<br />

predominant orientation of collagen fiber<br />

bundles.<br />

• Clinically and surgically significant because<br />

cuts can result in slow healing and increased<br />

scarring.<br />

5-17<br />

18<br />

6


Innervation and Blood Supply<br />

• The dermis has extensive innervation.<br />

• Monitor sensory receptors in the dermis and<br />

epidermis, and control both blood flow and gland<br />

secretion rates.<br />

• Tactile corpuscles and tactile (Merkel) cells perceive<br />

touch sensations, and work with a variety of other<br />

sensory nerve endings in the skin.<br />

• This rich innervation allows us to be very aware of<br />

our surroundings and to differentiate among the<br />

different kinds of sensory signals from receptors in<br />

the skin.<br />

5-19<br />

Nails<br />

• Scalelike modifications of the epidermis<br />

that form on the dorsal surfaces of the<br />

tips of the fingers and toes.<br />

• Protect the exposed distal tips and<br />

prevent damage or distortion during<br />

jumping, kicking, catching, or grasping.<br />

• Hard derivatives formed from the<br />

stratum corneum layer of the epidermis.<br />

5-20<br />

21<br />

7


Hair<br />

• Found almost everywhere on the body<br />

except the palms of the hands, the<br />

sides and soles of the feet, the lips, the<br />

sides of the fingers and toes, and<br />

portions of the external genitalia.<br />

• Most of the hairs on the human body<br />

are on the general body surface rather<br />

than the head.<br />

5-22<br />

23<br />

24<br />

8


3 Kinds of Hair<br />

• During our lives, we produce three<br />

kinds of hair:<br />

• lanugo<br />

• vellus<br />

• terminal hair<br />

5-25<br />

Functions of Hair<br />

• Protection<br />

• Heat retention<br />

• Prevents the loss of conducted heat from the<br />

scalp to the surrounding air<br />

• Facial expression<br />

• Sensory reception<br />

• Visual identification<br />

• Chemical signal dispersal<br />

5-26<br />

Hair Color<br />

• Result of the synthesis of melanin in the<br />

matrix adjacent to the papillae.<br />

• Variations in hair color reflect genetically<br />

determined differences in the structure of the<br />

melanin.<br />

• Environmental and hormonal factors<br />

• Age<br />

• Gray hair<br />

5-27<br />

9


Hair Growth and Replacement<br />

• Sometimes hair loss may be temporary<br />

as a result of one or more of the<br />

following factors: exposure to drugs,<br />

dietary factors, radiation, high fever, or<br />

stress.<br />

• Thinning of the hair, called alopecia can<br />

occur in both sexes, usually as a result<br />

of aging.<br />

5-28<br />

Exocrine Glands of the Skin<br />

• Sweat (sudoriferous) glands produce a<br />

watery solution that performs several<br />

specific functions.<br />

• merocrine (eccrine) sweat glands<br />

• apocrine sweat glands<br />

• Sebaceous glands produce an oily material<br />

that coats hair shafts and the epidermal<br />

surface.<br />

5-29<br />

30<br />

10


31<br />

Other <strong>Integumentary</strong> Glands<br />

• Ceruminous glands<br />

• Mammary glands<br />

• modified apocrine sweat glands<br />

5-32<br />

Burns<br />

• Major cause of accidental death, primarily as<br />

a result of their effects on the skin.<br />

• Usually caused by heat, radiation, harmful<br />

chemicals, sunlight, or electrical shock.<br />

• The immediate threat to life results primarily<br />

from fluid loss, infection, and the effects of<br />

burned, dead tissue.<br />

• Burns are classified according to the depth of<br />

tissue involvement.<br />

5-33<br />

11


Classification of Burns<br />

• First- and second-degree burns are<br />

called partial-thickness burns.<br />

• Third-degree burns are called fullthickness<br />

burns.<br />

• first-degree burns involve only the<br />

epidermis and are characterized by<br />

redness, pain, and slight edema<br />

• an example is sunburn<br />

5-34<br />

Classification of Burns<br />

• Second-degree burns involve the<br />

epidermis and part of the dermis.<br />

• The skin appears red, tan, or white, and<br />

is blistered and painful.<br />

• An example is a scald.<br />

5-35<br />

Classification of Burns<br />

• Third-degree burns involve the epidermis, dermis,<br />

and subcutaneous layer, which are often destroyed.<br />

• Regeneration may occur from the edge only, due to<br />

the absence of dermis.<br />

• Skin grafting is required to prevent abnormal<br />

connective tissue fibrosis and disfigurement.<br />

• Dehydration is a major concern because the entire<br />

portion of skin has been lost, and water cannot be<br />

retained.<br />

• Must be aggressively treated for dehydration.<br />

5-36<br />

12


Aging of the Integument<br />

• Skin repair processes take longer due to<br />

reduced number and activity of stem cells.<br />

• Skin forms wrinkles and becomes less<br />

resilient.<br />

• Skin’s immune responsiveness is diminished.<br />

• Skin becomes drier due to decreased<br />

sebaceous gland activity.<br />

• Altered skin and hair pigmentation.<br />

5-37<br />

Aging of the Integument<br />

• Sweat production diminishes.<br />

• Blood supply to the dermis is reduced<br />

leading to impaired thermoregulation.<br />

• Hair thinning and loss.<br />

• <strong>Integumentary</strong> production of vitamin D 3<br />

diminishes.<br />

• Development of skin cancers.<br />

5-38<br />

Skin Cancer<br />

• The most common type of cancer.<br />

• The greatest risk factor is exposure to<br />

UV rays of the sun.<br />

• The highest incidence is in people who<br />

have had severe sunburns, especially as<br />

children.<br />

5-39<br />

13

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