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Overview of Available LTMO Methods

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Quantitative Approaches (cont.)<br />

• Sample frequency – quantitative temporal<br />

analysis<br />

– Evaluate nature & strength <strong>of</strong> statistical trend<br />

• Compute measure <strong>of</strong> variability, periodicity<br />

– Rule-based decision tree to recommend<br />

sampling frequency based on trend,<br />

variability, average concentration<br />

– Simulation approach – recommend sampling<br />

frequency based on observed & projected<br />

rate <strong>of</strong> concentration change<br />

14

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