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R.A. Seaton, Gartnavel General Hospital, Glasgow

R.A. Seaton, Gartnavel General Hospital, Glasgow

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Infections treated with OPAT<br />

Infections treated with OPAT<br />

Number of patients<br />

350<br />

300<br />

250<br />

200<br />

150<br />

100<br />

50<br />

Diagnoses for OPAT patients (n=2063)<br />

Other<br />

BJI<br />

SSTI<br />

Number of patients<br />

100<br />

80<br />

60<br />

40<br />

20<br />

Diagnoses for OPAT patients excluding SSTI and BJI<br />

99<br />

89<br />

68<br />

46<br />

34 32<br />

27<br />

13 14<br />

0<br />

2001 2002 2003 2004 2005 2006 2007 2008<br />

Year<br />

0<br />

Bact/Endo<br />

Meninigits<br />

Syphilis<br />

Lyme<br />

LRTI<br />

UTI<br />

TB<br />

Typhoid<br />

Other<br />

LRTI, lower respiratory tract infection; TB, tuberculosis; UTI, urinary tract infection<br />

<strong>Seaton</strong> RA. Unpublished data<br />

<strong>Seaton</strong> RA. Unpublished data<br />

Community treatment pathway for<br />

SSTIs: empiric antibiotic choice<br />

Yes<br />

Anti-MRSA<br />

therapy<br />

Patient at risk for MRSA?<br />

No<br />

Ceftriaxone<br />

±<br />

clindamycin<br />

Patient group direction for SSTIs<br />

• ‘Patient group’: non-lifethreatening<br />

cellulitis amenable for<br />

home care and requiring i.v.<br />

therapy<br />

• Uniform therapeutic management<br />

• Suitable protocol in place<br />

• Exclusions<br />

• Prior physician review<br />

• Indications for specialist review<br />

• Indications for IVOST<br />

• Trained, experienced staff<br />

• Approved by ADTC<br />

IVOST, i.v. antibiotic – oral switch therapy<br />

<strong>Seaton</strong> RA et al. J Antimicrob Chemother 2005;55:764–767

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