Liability in Obstetrical and Gynecologic Ultrasound - Cmebyplaza.com
Liability in Obstetrical and Gynecologic Ultrasound - Cmebyplaza.com
Liability in Obstetrical and Gynecologic Ultrasound - Cmebyplaza.com
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MTX <strong>and</strong> Anomalies<br />
Am<strong>in</strong>opter<strong>in</strong>/MTX Syndrome<br />
• Dose effect (threshold)<br />
• Tim<strong>in</strong>g<br />
– > 10 mg/week<br />
–2-2.52.5 weeks<br />
• Undifferentiated cells<br />
• All or none effect (SAB)<br />
–4-10 weeks (6-8 weeks)<br />
• Effect on differentiat<strong>in</strong>g cells<br />
Clayton et al. Obstet Gynecol 2006;107:598-604.<br />
604.