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Terbutaline • Class: – Bronchodilator, uterine smooth muscle relaxant • Indications: –Asthma – Control of pre-term labor • Contraindications: – Hypersensitivity • Interactions: – Additive effects with other adrenergics – Β-adrenergic blockers may negate Terbutaline continued… • Administration: – Pre-term labor: • 10 µg/min – Increase every 10 minutes until contractions stop. – Max dose is 80 µg/min. – Asthma • MDI or SVN (1-3 mg/3 ml NS) • SQ .25 mg – Give q 15-30 minutes – Max .5 mg in 4 hours Neuromuscular Blocking Agents NBA – Non-Depolarizing • Indications: – Facilitation of mechanical ventilation • Mechanism of action: – Act by blocking the binding of ACh to its receptors. – Directly block the inotropic activity of ACh receptors. Non-Depolarizing NBA – Non-Depolarizing continued… • Interaction: – Intensity and duration of paralysis may be prolonged by pre-treatment with: • Succinylcholine • Lidocainei • Quinidine • Procainamide • Β-adrenergic blocking agents • KCL losing diuretics • Magnesium NBA – Non-Depolarizing continued… • Administration – Depends on the specific drug used. • Classified as short, intermediate, and long acting. – They may have a similar onset of action. – The duration of effectiveness ect e ess will vary. – Use an infusion pump! Note the following slides…. 2
Short Acting Agent Onset Duration Mivacron 2 – 5 minutes 15 – 20 minutes Raplon 35 – 219 seconds 6 – 30 minutes Zemeron 1 – 3 minutes 31 minutes Intermediate Acting Agent Onset Duration Tracrium 2.5 – 5 minutes 20 – 45 minutes Nimbex 2 – 3 minutes 30 – 40 minutes Pavulon 2 – 3 minutes 60 – 90 minutes Norcuron 2 – 3 minutes 25 – 40 minutes Long Acting Agent Onset Duration Nuromax 2.5 – 13 minutes 39 – 232 minutes NBA – Non-Depolarizing continued… • Watch Out’s: – The patient needs to be intubated. – These medications do not sedate or provide analgesia. Arduan 2.5 – 5 minutes 35 – 175 minutes Propofol (Diprivan®) • Class: – Anesthetic • Indications: – Maintenance of sedation in intubated and mechanically intubated patients. • Contraindications: – Not recommended in patients < 3 years old. – Avoid in patients with severe systemic disease. Propofol (Diprivan®) continued… • Interactions: – Additive CNS and respiratory effects when it is combined with • Alcohol • Antihistamines • Opiates • Other sedative/hypnotics 3
Page 1: Why This Again? Transport Drugs Jam
Page 5 and 6: Procainamide • Class: - Antidysrh
Page 7 and 8: Nipride® continued… Head/Spinal
Page 9 and 10: Blood Grouping • Historically, Ty
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