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The Official Publication of ITACCS - International Trauma ...

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*<br />

*For infections due to susceptible strains<br />

<strong>of</strong> indicated organisms.<br />

Careful inquiry should be made<br />

concerning previous hypersensitivity<br />

reaction, as serious and occasionally<br />

fatal anaphylactic reactions have been<br />

reported in patients receiving therapy<br />

with penicillins. ZOSYN is contraindicated<br />

in patients with a history <strong>of</strong> these<br />

reactions to any <strong>of</strong> the penicillins,<br />

cephalosporins, or ß-lactamase inhibitors.<br />

While ZOSYN possesses the characteristic<br />

low toxicity <strong>of</strong> the penicillin group <strong>of</strong><br />

antibiotics, periodic assessment <strong>of</strong> organ<br />

system functions, including renal, hepatic,<br />

and hematopoietic, during prolonged<br />

therapy is advisable.<br />

During clinical trials, pseudomembranous<br />

colitis has been rarely reported (

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