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Overview of Hypothesis Testing

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But I Have All Zeros!<br />

Calculate l 95% upper bound<br />

• Known # <strong>of</strong> trials without an event (2.11<br />

van Belle 2002, Louis 1981)<br />

• Given no observed events in n trials,<br />

95% upper bound on rate <strong>of</strong> occurrence<br />

is 3 / (n + 1)<br />

• No fatal outcomes in 20 operations<br />

• 95% upper bound on rate <strong>of</strong><br />

occurrence = 3/(20+1)= 0.143, so<br />

the rate <strong>of</strong> occurrence <strong>of</strong> fatalities<br />

could be as high as 14.3%

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