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http://www.cimr.cam.ac.uk/links/codon.htm<br />
Substitution matrices for aa<br />
Amino acids are not equal:<br />
1. Some are easily<br />
substituted, similar:<br />
• biochemical properties<br />
• structure<br />
2. Some mutations occur<br />
more often due to similar<br />
codons<br />
The two above give us<br />
substitution matrices<br />
http://www.people.virginia.edu/~rjh9u/aminacid.html<br />
orange: nonpolar and hydrophobic.<br />
green: polar and hydrophilic<br />
magenta box are acidic<br />
light blue box are basic
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