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Perspectives on Vascular Closure Device and the Latest Evidence

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<str<strong>on</strong>g>Perspectives</str<strong>on</strong>g> <strong>on</strong> <strong>Vascular</strong> <strong>Closure</strong> <strong>Device</strong>s<br />

Meta-analysis: VCDs Vs. MC Post Percutaneous Procedures<br />

When <strong>the</strong>y repeated <strong>the</strong> analysis <strong>on</strong>ly in<br />

trials with explicit intenti<strong>on</strong> to treat<br />

analysis, <strong>the</strong> RR of hematoma was<br />

higher in <strong>the</strong> VCD group (1.89;95%<br />

CI=1.13-3.15) in 4 trials involving 404<br />

pts in VCD <strong>and</strong> 259 pts in MC group.<br />

The RR of developing pseudoaneurysm<br />

was also higher in <strong>the</strong> VCD group (5.40,<br />

95% CI=1.21-24.5). The authors<br />

c<strong>on</strong>cluded that “<strong>the</strong>re is <strong>on</strong>ly marginal<br />

evidence that VCD are effective <strong>and</strong><br />

<strong>the</strong>re is reas<strong>on</strong> for c<strong>on</strong>cern that <strong>the</strong>se<br />

devices MAY increase <strong>the</strong> risk of<br />

hematoma <strong>and</strong> pseudoaneurysm.”<br />

Koreny M et al JAMA2004;291:350-7

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