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Perspectives on Vascular Closure Device and the Latest Evidence

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Study<br />

<str<strong>on</strong>g>Perspectives</str<strong>on</strong>g> <strong>on</strong> <strong>Vascular</strong> <strong>Closure</strong> <strong>Device</strong>s<br />

Large C<strong>on</strong>trolled/ Meta-analysis Studies: VCDs Vs MC<br />

Study<br />

Type<br />

N<br />

<strong>Device</strong><br />

Comparis<strong>on</strong><br />

End Point<br />

Outcomes<br />

Cura et al Registry 2918 VCD vs. mc Vas. Complicati<strong>on</strong> AngioSeal 2.9%<br />

Perclose 3.2%<br />

MC 3.1% P=NS<br />

Dangas et al Registry 5039 VCD vs. MC Surgicl Repair VCD 2.5%<br />

MC1.5% P=0.03<br />

Resnic et al Rigietry 3027 VCD vs. MC Vas. Complicati<strong>on</strong> MC5.5%<br />

Vcd3.0% P=0.002<br />

Dangas et al<br />

Tavris et al<br />

Exaire e tal<br />

Koreny et al<br />

Viatkus<br />

Nikolsky et al<br />

Pooled<br />

R<strong>and</strong>.Trial<br />

ACC-<br />

NCDR<br />

Target s<br />

Stbstudy<br />

Metaanalysi<br />

Metaanalysis<br />

Metaanalysis<br />

Applegagte et al Registry 4699 AngioSeal vs<br />

MC<br />

2095 VCD vs. mc <strong>Device</strong> Complic. VCD8.5%<br />

MC5.9% P=0.02<br />

166,680 VCD vx. MC Vasc. Complic. 1.05to 1.48% VCD<br />

1.7% for MC P

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