Pharmacology and Pharmacokinetics of Alcohol and Opioids ...

More documents

Recommendations

Info

Opioid Receptors and Ligands Receptor subtypes Agonists Antagonists Second messengers mu-opioid Morphine Beta- Endorphin Naloxone, Naltrexone (-)cAMP, (+)gK+ deltaopioid DPDPE enkephalins Naltrindol (-)cAMP, (+)gK+ kappaopioid ketocyclasocin dynorphinA 1-32 Norbinaltorphimine (-)gCa 2+
Antagonist (e.g. naltrexone) Antagonists have no effect on activity by themselves, but block the activity of agonists and partial agonists
Page 1 and 2: Tufts Health Care Institute’s Pro
Page 3 and 4: Morbidity and Mortality • Alcohol
Page 5 and 6: • Pharmacokinetics - The processe
Page 7 and 8: Opiate Drug Concentration vs. Time
Page 9 and 10: BAC vs Time after Oral Alcohol Bloo
Page 11 and 12: Factors Affecting Bioavailability
Page 13 and 14: Oral Modified-Release Opioid Produc
Page 15 and 16: Morphine Metabolism •Glucuronidat
Page 17 and 18: Alcohol Morphine Metabolic Interact
Page 19 and 20: •Pharmacodynamics - The processes
Page 21: Pharmacodynamics of Opiates • Dep
Page 25 and 26: Ethanol is a Drug With Complex Phar
Page 27 and 28: Pharmacodynamic interactions betwee
Page 29 and 30: Alcohol Increases the Activity of E
Page 31 and 32: The NMDA- Glutamate Receptor inhibi
Page 33: Summary of Opiate Alcohol Interacti

Pharmacology and Pharmacokinetics of Alcohol and Opioids ...

Create successful ePaper yourself

Delete template?

Save as template?