Pharmacology and Pharmacokinetics of Alcohol and Opioids ...

More documents

Recommendations

Info

Opioids as NMDA Antagonists
Summary of Opiate Alcohol Interactions Pharmacokinetic Interactions • Liberation of modified release oral formulations • Metabolism – Acute and chronic effects Glucuronidation, CYP3A4, liver disease Pharmacodynamic Interactions • Acute release of endorphins by alcohol • Changes in opiate receptors with chronic alcohol • Ethanol facilitation of opiate effects at the receptor by actions on G-protein coupling • NMDA receptor inhibition by alcohol and opiates
Page 1 and 2: Tufts Health Care Institute’s Pro
Page 3 and 4: Morbidity and Mortality • Alcohol
Page 5 and 6: • Pharmacokinetics - The processe
Page 7 and 8: Opiate Drug Concentration vs. Time
Page 9 and 10: BAC vs Time after Oral Alcohol Bloo
Page 11 and 12: Factors Affecting Bioavailability
Page 13 and 14: Oral Modified-Release Opioid Produc
Page 15 and 16: Morphine Metabolism •Glucuronidat
Page 17 and 18: Alcohol Morphine Metabolic Interact
Page 19 and 20: •Pharmacodynamics - The processes
Page 21 and 22: Pharmacodynamics of Opiates • Dep
Page 23 and 24: Antagonist (e.g. naltrexone) Antago
Page 25 and 26: Ethanol is a Drug With Complex Phar
Page 27 and 28: Pharmacodynamic interactions betwee
Page 29 and 30: Alcohol Increases the Activity of E
Page 31: The NMDA- Glutamate Receptor inhibi

Pharmacology and Pharmacokinetics of Alcohol and Opioids ...

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?