ANNUAL REPORT - Saint Joseph Mercy Health System
ANNUAL REPORT - Saint Joseph Mercy Health System
ANNUAL REPORT - Saint Joseph Mercy Health System
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2010<br />
Annual Report<br />
Data Represented 2009
Table of Contents<br />
INTRODUCTION (2 - 3)<br />
2 Letter from the Medical Director<br />
3 Letter from Cancer Committee Chair<br />
EXECUTIVE SUMMARY (4 - 5)<br />
FOUNDATIONS OF CANCER CARE (6 -15)<br />
6 American College of Surgeons’ Commission on Cancer:<br />
Accreditation as a Teaching Hospital Cancer Program<br />
6 Cancer Program Overview<br />
7 Facilities<br />
8 Oncology Physician Specialists<br />
8 Medical Oncology<br />
9 Radiation Oncology<br />
10 Surgical Oncology<br />
10 Multidisciplinary Clinics<br />
11 Multidisciplinary Programs<br />
11 Breast Cancer Program<br />
12 Gastrointestinal Cancer Program<br />
(Colorectal, Hepatobiliary)<br />
13 Genitourinary Cancer Program<br />
(Renal, Prostate)<br />
13 Lung Cancer Program<br />
14 Gynecologic Oncology Program<br />
14 Neurologic Cancer Program<br />
(Brain, Spinal Cord)<br />
14 Head & Neck Cancer Program<br />
14 Endocrine Cancers (Thyroid)<br />
14 Skin Cancers (Melanoma)<br />
CANCER RESEARCH (16)<br />
16 MICHIGAN CANCER RESEARCH CONSORTIUM<br />
COMMUNITY CLINICAL ONCOLOGY PROGRAM<br />
(MCRC-CCOP)<br />
CARE ACROSS THE CONTINUUM (17)<br />
17 NATIONAL CANCER INSTITUTE COMMUNITY<br />
CANCER CENTERS PROGRAM GRANT (NCCCP)<br />
17 Program Overview<br />
17 Nurse Navigators<br />
18 Community Partnerships<br />
18 <strong>Health</strong> Disparities<br />
19 Biospecimen Research Initiatives<br />
19 Cancer Survivorship and Palliative Care Services<br />
PATIENT CENTEREDNESS (20)<br />
20 Oncology Patient Advocates Team<br />
20 Patient Satisfaction<br />
20 A Patient Speaks<br />
QUALITY INITIATIVES AND OUTCOMES (22 -27)<br />
22 Oncology & Infusion Collaborative Practice<br />
Team: Review of Chemotherapy Safety<br />
23 Chemotherapy Infusion Clinic: Streamlining<br />
<strong>System</strong>s - Chemotherapy Order Process<br />
23 Department of Radiation Oncology:<br />
Streamlining <strong>System</strong>s<br />
23 Cardiothoracic Surgeons: Benchmarking Utilizing<br />
the Society of Thoracic Surgeons Database<br />
24 Medical Oncologists: Quality Oncology<br />
Practice Initiative (QOPI)<br />
24 Medical Oncologists: Michigan Oncology<br />
Clinical Treatment Pathways Program<br />
24 Breast Program Quality Initiatives<br />
25 Cancer Research Audits (2009-2010)<br />
26 American College of Surgeons’ Commission<br />
on Cancer: Outcomes Comparison<br />
APPENDICES (28-34)<br />
28 Appendix A: Tumor Registry Analytical Cases<br />
(2009) by Diagnostic Site<br />
30 2009 Best General Summary Stages<br />
31 2009 Tumor Boards & Registry<br />
32 2009-2010: Highlights of Scholarly Activities<br />
34 2009-2010: Publications & Resident Awards<br />
SJMHS Dermatology<br />
2010 Annual Cancer Report • 1
Letter from the<br />
Medical Director<br />
Philip J. Stella, MD, Medical Director<br />
St. <strong>Joseph</strong> <strong>Mercy</strong> Cancer Program<br />
Principal Investigator, Michigan Cancer Research Consortium<br />
I am pleased to present the 2009-10 annual report of the St. <strong>Joseph</strong> <strong>Mercy</strong> Cancer Program. This<br />
past year truly has been eventful, highlighted by the awarding of a National Cancer Institute (NCI)<br />
Community Cancer Centers Program (NCCCP) contract. This prestigious award from the NCI signifies<br />
our program as one of a select group of community cancer programs in the country. It recognizes<br />
excellence in research and supports our efforts toward high-quality multidisciplinary care; in addition,<br />
it supports resources for a genetics counselor and nurse navigators, and provides resources for the<br />
underserved populations. The NCCCP contract also assists in the development of a tissue repository<br />
to help advance translational research.<br />
We are excited about the long-awaited expansion of our multidisciplinary clinics this coming fall. In<br />
addition to a lung cancer clinic, we will now be able to see patients with breast, gastrointestinal (GI),<br />
prostate, head and neck cancer, and neuro-oncologic malignancies in a multidisciplinary fashion<br />
supported by nurse navigators to help facilitate timely access to state-of-the-art care for patients and<br />
providers.<br />
Speaking of access, we have expanded the oncology program with new satellites in Canton and Chelsea<br />
as well as the established sites in Brighton and Livonia. We look forward to adding a fellowship-trained<br />
breast surgeon to head a superb team of specialists and staff providing optimal breast care.<br />
I am particularly pleased with the work of our patient advocate committee. Under the leadership of Pastor<br />
Dave McNeil and Beth LaVasseur, RN, MSN, we have developed partnerships with American Cancer<br />
Society (ACS) and the Wellness Community to expand the services we provide to cancer patients.<br />
With patient representation on our program committees, we are fulfilling our mission to truly be patientcentered.<br />
Our work with Blue Cross Blue Shield of Michigan (BCBSM) to support quality initiatives such as Michigan<br />
Breast Oncology Quality Initiative (MiBOQI), Quality Oncology Practice Initiative (QOPI) and the Pathway<br />
Project is putting us on the cutting edge of measuring and implementing cost effective quality programs<br />
that are models of care garnering national recognition.<br />
Finally, we are promoting early detection and screening through an all-digital mammography network,<br />
a robust screening colonoscopy program and annual prostate and skin cancer screening events.<br />
In what promises to be a paradigm shifting approach, our Smoking Cessation Collaborative Practice<br />
Team has developed a program to train a champion in physician offices to identify and provide<br />
evidence-based intervention to our patients who are tobacco dependent.<br />
With 10 million dollars in grants and contracts over the next four or five years, a faculty committed to<br />
research and access to the latest technologic advancements such as robotic surgery and Cyberknife ® ,<br />
we are confident that we can provide the best cancer care for our patients.<br />
2 • 2010 Annual Cancer Report
Letter from the<br />
Cancer Committee Chair<br />
Timothy McHugh, MD, Chairperson<br />
St. <strong>Joseph</strong> <strong>Mercy</strong> Cancer Committee<br />
The Cancer Committee is a multidisciplinary committee charged with oversight of the quality of<br />
care delivered to patients as they traverse the health care system. As Chair of the SJMHS Cancer<br />
Committee, I am proud to report that we continue to exceed the standards for American College of<br />
Surgeons’ Commission on Cancer Hospital Teaching Programs. Accreditation by the American College<br />
of Surgeons’ Commission on Cancer is a very rigorous process that documents our compliance with<br />
multiple quality and process improvement initiatives set to define cancer programs of excellence.<br />
Through our accreditation by the American College of Surgeons our committee follows a comprehensive<br />
structure for the ongoing measurement of the quality of our program for all cancer related services.<br />
Only 25% of community cancer programs in the country are accredited. The standards measured<br />
represent care across the continuum: prevention, early-diagnosis, pre-treatment evaluation, staging,<br />
optimal treatment, rehabilitation, and surveillance for recurrent disease, support services and end of life<br />
care. We were particularly pleased this past year with the increasing amount of quality measurement<br />
data made available to the Committee and the increased focus on multidisciplinary care to improve the<br />
patient experience. A representative from the American Cancer Society has also joined our committee,<br />
which provides us with an excellent community partnership and expanded resources for our patients.<br />
At each Cancer Committee meeting we review the eight categories of ACOS standards, which provides<br />
us the opportunity to organize and manage the cancer program to assure multidisciplinary, integrated<br />
and comprehensive oncology services. Each of our twenty-five members is actively engaged in<br />
discussing and accepting the challenge to accomplish the newly identified goals the Committee sets<br />
for the program.<br />
Throughout this report you will see examples of the quality of care and process improvements that we<br />
review and oversee on a regular basis to assure the cancer program is not only meeting but exceeding<br />
the needs of our patients.<br />
2010 Annual Cancer Report • 3
EXECUTIVE SUMMARY<br />
The opening of the Robert H. and Judy Dow Alexander Cancer Care Center<br />
at St. <strong>Joseph</strong> <strong>Mercy</strong> Hospital in Ann Arbor in 1993 was the beginning of an<br />
extraordinary time in the evolution of cancer care in our community. In a<br />
short 16 years, SJMHS has developed an all-expansive oncology program<br />
that is recognized for its leadership and innovation in developing cancer<br />
services that continually look to the future for the newest technology,<br />
advanced treatment options, breakthrough medications, and programs<br />
that improve the cancer experience for individuals and families.<br />
The following highlights provide a historical context and illustrate the<br />
accomplishments and growth of the SJMHS cancer program.<br />
4 • 2010 Annual Cancer Report
° The Robert H. and Judy Dow Alexander Cancer<br />
Care Center on the SJMHS campus in Ann<br />
Arbor began as a new 30,000 square foot facility<br />
housing chemotherapy infusion services, medical<br />
oncology, laboratory services, and program<br />
offices. As the first dedicated cancer center in<br />
our service area, it became the model for care.<br />
Today, SJMHS cancer centers include additional<br />
state-of-the-art facilities in Brighton and Canton,<br />
with a fourth being planned for Chelsea. Services<br />
in all centers include both chemotherapy and<br />
radiation therapy as well as multidisciplinary clinic<br />
space and all ancillary services.<br />
° When the oncology program was being formalized<br />
in the early 1990’s, a total of four patients were<br />
enrolled in clinical trials through our affiliation with<br />
the Toledo Community Clinical Oncology Program.<br />
In 2009, SJMHS enrolled over 200 patients on both<br />
treatment and cancer control protocols.<br />
° The establishment of SJMHS leadership in cancer<br />
clinical trials research has been extraordinary<br />
under the leadership of Philip J. Stella, MD, Medical<br />
Director. With the vision to develop a leadingedge<br />
program, Dr. Stella and staff put in place the<br />
elements needed to become a National Cancer<br />
Institute funded Community Clinical Oncology<br />
Program. The Ann Arbor Regional CCOP was<br />
formed, receiving NCI support commencing in<br />
1994. Since that time, a total of 11 other Michigan<br />
health systems and one Connecticut hospital have<br />
joined what is now the Michigan Cancer Research<br />
Consortium CCOP (MCRC CCOP) -- renamed to<br />
better reflect its membership. SJMHS has been the<br />
fiscal agent for the CCOP since its inception; Dr.<br />
Stella has been the Principal Investigator this entire<br />
time. In 2009, over 600 patients were enrolled<br />
in research studies, and 2,000+ individuals on<br />
studies are being followed each year. The MCRC<br />
CCOP has achieved a national reputation for<br />
quality research and has been funded by the NCI<br />
continuously since 1994. It is one of the largest<br />
CCOPs in the country.<br />
° The original vision for the Robert H. and Judy Dow<br />
Alexander Cancer Care Center was to provide all<br />
oncology services in one location and to establish<br />
“clinics” where physicians of many disciplines<br />
would come to the patient to coordinate the<br />
diagnostic and treatment processes. Our original<br />
hope was to develop multidisciplinary clinics<br />
for the several major cancer diagnoses: breast,<br />
colon, lung and prostate malignancies. Not only<br />
do we have multidisciplinary physician groups<br />
for each of these disease sites, but we have them<br />
for gastrointestinal, genitourinary, gynecologic,<br />
neurologic, endocrine, head and neck, and<br />
cutaneous malignancies. This has become our<br />
model of care.<br />
° In 1993, our measurements related to the quality<br />
of care we were providing utilized data from<br />
our Tumor Registry and compared our data with<br />
that of other hospital tumor registries. We were<br />
able to review such things as stage of disease<br />
at diagnosis, numbers of patients enrolling in<br />
clinical trials, and morbidity and mortality data.<br />
Over the years we chose to participate in the<br />
multiple cancer quality databases as they<br />
became available so as to develop one of the<br />
most comprehensive and far-reaching quality<br />
programs in existence today. These databases<br />
include the National Comprehensive Cancer<br />
Network (NCCN) Breast Cancer Database, the<br />
Quality Oncology Physician Initiative (QOPI)<br />
sponsored by the American Society of Clinical<br />
Oncology (ASCO), the Society of Thoracic<br />
Surgeons Database, the Blue Cross & Blue<br />
Shield of Michigan Pathways Project, and the<br />
American College of Surgeons Tumor Registry.<br />
We clearly want to know how our care compares<br />
with that around the country and “continuous<br />
improvement” is a framework which we embrace.<br />
° One of our most recent and most exciting<br />
accomplishments occurred in April 2010 when<br />
the SJMHS cancer program was awarded a<br />
$2.5 million NCI Community Cancer Centers<br />
Program (NCCCP) grant. This grant program is<br />
competitive and SJMHS was among<br />
only 14 sites selected from applications across<br />
the country. Funding for this program comes<br />
from the American Recovery and Reinvestment<br />
Act; and the funds will support eleven oncology<br />
program positions including genetics coordinator,<br />
continuum of care coordinator, and additional<br />
nurse navigators among others. It supports<br />
methods to reduce healthcare disparities and<br />
improve access to clinical trials. It is discussed<br />
in more detail later in this report.<br />
° In mid-2009, SJMHS was notified that the<br />
oncology program was awarded $199,000<br />
to be utilized through August 2011 to fund<br />
two Nurse Navigator positions that focus on<br />
education related to clinical trials as well as<br />
actual recruitment to research studies. This<br />
funding, too, comes via the National Institutes<br />
of <strong>Health</strong> and the American Recovery and<br />
Reinvestment Act and is designed to both<br />
accelerate and promote scientific research<br />
and allow for job creation and retention.<br />
2010 Annual Cancer Report • 5
FOUNDATIONS OF CANCER CARE<br />
American College of Surgeons’<br />
Commission on Cancer: Teaching<br />
Hospital Cancer Program<br />
Originating in 1922 by the American College<br />
of Surgeons’ (ACoS), the Commission on<br />
Cancer establishes standards to ensure quality,<br />
multidisciplinary, and comprehensive cancer care<br />
delivery. Accreditation by the Commission on<br />
Cancer (CoC) is granted only to those organizations<br />
that have voluntarily committed to provide the best<br />
in cancer diagnosis and treatment and are able<br />
to comply with established CoC standards. These<br />
standards ensure that a full range of state-of-the-art<br />
diagnostic, treatment, and supportive services are<br />
offered at accredited facilities.<br />
St. <strong>Joseph</strong> <strong>Mercy</strong> Hospital and the SJMH Cancer<br />
Program have been accredited by the Commission<br />
on Cancer since 1986, receiving accreditation<br />
with commendation in 2007 as a Teaching Hospital<br />
Cancer Program. A rigorous evaluation and review<br />
of our performance and compliance with CoC<br />
standards will again be conducted in 2010.<br />
Cancer Program Overview<br />
<strong>Saint</strong> <strong>Joseph</strong> <strong>Mercy</strong> <strong>Health</strong> <strong>System</strong> (SJMHS) is one<br />
of the most advanced providers of comprehensive<br />
cancer care in Michigan with three patient-centered,<br />
dedicated cancer centers and a fourth one soon to<br />
open. Our multidisciplinary approach provides highquality<br />
patient outcomes that are based on leadingedge<br />
research and clinically proven therapies.<br />
Newly-diagnosed cancer patients average 2,400<br />
each year (see Appendix A, Tumor Registry 2009<br />
Analytic Cases by Diagnostic Site).<br />
Integral to the SJMHS oncology program is a full<br />
spectrum of interdisciplinary caregivers who are<br />
highly experienced and passionate about their<br />
work. Chemotherapy certified nurses in Ann Arbor<br />
provide infusion services to an average of 65 patients<br />
per day. Oncology social workers are available for<br />
individual and family counseling at all phases of the<br />
cancer experience; they also lead numerous support<br />
groups which have been a mainstay of our program<br />
for 25+ years. The Palliative Care Team works across<br />
all settings, developing and implementing plans for<br />
care when comfort is the goal. Nurse navigators,<br />
home care case managers, dieticians, pastoral<br />
care chaplains and hospice staff are key members<br />
of the oncology team to ensure we address the<br />
comprehensive needs of our patient population.<br />
2009 Program Statistics<br />
Topic<br />
Data Point<br />
Newly Diagnosed Cancer Patients 2,448<br />
Radiation Treatments Delivered 24,85<br />
CyberKnife ® Fractions Delivered 614<br />
Chemotherapy & Infusion Treatments 18,847<br />
Mammograms Performed 54,000<br />
GI Endoscopies Performed 16,000<br />
Lung Cancer Surgical Cases 477<br />
# of Patients Enrolled in Clinical Trials since 2005 1,300<br />
6 • 2010 Annual Cancer Report
Additional Cancer<br />
Centers Opened<br />
November 2009<br />
St. Joesph <strong>Mercy</strong> Canton<br />
Cancer Center<br />
May 2006<br />
St. Joesph <strong>Mercy</strong> Brighton<br />
Cancer Center<br />
Facilities<br />
Opened in 1993, the Robert H. and Judy Dow<br />
Alexander Cancer Care Center (also known as<br />
St. <strong>Joseph</strong> <strong>Mercy</strong> Cancer Care Center) at St. <strong>Joseph</strong><br />
<strong>Mercy</strong> Hospital in Ann Arbor was a leader in cancer<br />
center design, focusing on the inclusion of all<br />
outpatient services under one roof. It is a 45,000+<br />
square foot outpatient facility housing radiation<br />
oncology, a large chemotherapy/infusion clinic,<br />
laboratory, medical and gynecologic oncology<br />
physician offices, the Michigan Cancer Research<br />
Consortium CCOP operations office, and oncology<br />
program administration. Multidisciplinary clinic<br />
space affords patients the opportunity to be evaluated<br />
by all oncology physician specialists in one<br />
setting. The Radiation Oncology Department houses<br />
Michigan’s first Cyberknife ® Radiosurgery Center<br />
and a dedicated brachytherapy surgical suite.<br />
This outpatient cancer center links to the new St.<br />
<strong>Joseph</strong> <strong>Mercy</strong> Hospital with a 60,000 square-foot<br />
Surgery Pavilion, incorporating 17 surgical suites<br />
equipped for the latest minimally invasive procedures.<br />
A beautiful 30-bed inpatient oncology unit<br />
located on the eleventh floor offers a panoramic<br />
view of the surrounding countryside.<br />
Two additional cancer centers provide comprehensive<br />
care to patients in the SJMHS service area. In May<br />
2006, SJMHS opened the $13.6 million Warren R. &<br />
Lauraine A. Hoenshield Cancer Center (also known<br />
as St. <strong>Joseph</strong> <strong>Mercy</strong> Brighton Cancer Center),<br />
20 miles north of Ann Arbor. This is one of the<br />
fastest growing communities in the state, and this<br />
Center houses the only linear accelerator in<br />
Livingston County. Prior to its opening, patients undergoing<br />
radiation therapy drove an average of 40<br />
minutes to a treatment facility. The chemotherapy<br />
treatment area includes 15 treatment bays. Each bay<br />
overlooks a healing garden with bright, modern-looking<br />
sculptures. The first bay is considered a retreat<br />
area where patients can play cards, games or work<br />
on computers. The design team consulted with both<br />
patients and employees throughout the project<br />
which has resulted in a cancer center with a healing<br />
environment of soothing colors, water fountains,<br />
murals and original artworks.<br />
The new St. <strong>Joseph</strong> <strong>Mercy</strong> Canton Cancer Center<br />
in Canton, Michigan opened in late November 2009.<br />
This facility duplicates the St. <strong>Joseph</strong> <strong>Mercy</strong> Brighton<br />
Cancer Center described above, offering both chemotherapy<br />
and radiation oncology services. Plans<br />
are underway to open a fourth cancer treatment<br />
center in Chelsea, Michigan within the next year.<br />
2010 Annual Cancer Report • 7
FOUNDATIONS OF CANCER CARE (con’t)<br />
Oncology Physician Specialists<br />
Medical Oncology<br />
Medical oncologists/hematologists are the<br />
mainstay for cancer treatment and most often are<br />
the coordinators of the comprehensive care required<br />
by oncology patients. At SJMH, two new physicians<br />
came on board in 2009 for a total of 11 medical<br />
oncologists in three physician practices. All<br />
participate in clinical trials through the Michigan<br />
Cancer Research Consortium and are the lead<br />
accruers to study protocols. In addition, they provide<br />
leadership to the multiple tumor boards where<br />
patient cases are presented for input and direction<br />
from a group of multispecialty physicians.<br />
2009 Critical Review Cases<br />
Tumor Board<br />
Cases<br />
Ann Arbor<br />
General (Includes Lung, GI) 155<br />
Breast Cancer 272<br />
Genitourinary Cancers 28<br />
Head & Neck Tumors 80<br />
Livingston 59<br />
The medical oncologists at SJMHS participate in all<br />
multidisciplinary clinics and interdisciplinary advisory<br />
groups. In the past year they presented a total of<br />
seven grand rounds for the Department of Medicine.<br />
They provide program leadership in multiple areas<br />
including membership on the SJMHS Oncology<br />
Institutional Review Board and various quality<br />
improvement initiatives.<br />
Medical oncologists oversee the chemotherapy<br />
infusion clinics in all cancer centers. They worked<br />
closely with nursing staff this year to evaluate the<br />
safety of chemotherapy ordering and administration<br />
at SJMHS and undertook steps to develop/refine the<br />
chemotherapy physician order entry system. Over<br />
16,000 chemotherapy doses were analyzed with<br />
only 17 errors (0.1%) that reached the patient; none<br />
of these had negative outcomes for the patient. The<br />
Oncology & Infusion Services Collaborative Practice<br />
Team is currently working on standardized chemotherapy<br />
order forms, with 17 presently in place.<br />
During 2009, the following guidelines were<br />
created/revised and implemented:<br />
° Management of Tumor Lysis Syndrome<br />
° Guidelines for Use of Antiemetics in the Adult<br />
Patient Receiving Chemotherapy<br />
° Guidelines for the Administration of Immune<br />
Globulin (Intravenous)<br />
2009 Chemotherapy and Infusion Volumes<br />
Ann Arbor<br />
Brighton<br />
Chemotherapy 7631 2234<br />
Blood Transfusions 239 158<br />
Other Infusions 5698 2920<br />
8 • 2010 Annual Cancer Report
Radiation Oncology<br />
Radiation oncology services are available in the St. <strong>Joseph</strong> <strong>Mercy</strong> Cancer Care Center (Ann Arbor) and<br />
both the Brighton and Canton facilities. Walter Sahijdak, MD, Medical Director, and five radiation oncologists<br />
provide expertise in the full spectrum of radiation therapy services.<br />
In 2007, SJMHS unveiled the first CyberKnife ® in Michigan. CyberKnife ® represents the latest generation of<br />
radiosurgery systems, combining image guidance technology with a compact linear accelerator. It has the<br />
flexibility to move in three dimensions to focus on the targeted area for treatment practically anywhere in the<br />
body. It has demonstrated success with a wide spectrum of cancers including brain, lung, prostate, pancreas,<br />
liver, and head/neck. The very precise radiation treatment can pinpoint and destroy tumors deep inside the<br />
body with no incisions, minimal side effects, no pain, and immediate return to normal activity.<br />
SJMHS has one of the few dedicated brachytherapy surgical suites in North America, offering both highdose-rate<br />
(HDR) and low-dose-rate (LDR) brachytherapy treatments for prostate, gynecologic, head/neck<br />
and breast cancers.k and breast ca<br />
2009 Radiation Oncology Patient<br />
Volumes & Services<br />
Ann Arbor<br />
Brighton<br />
New Patient Consults 958 251<br />
Radiation Treatments 17,876 6,975<br />
CyberKnife ® Consults 87 N/A<br />
CyberKnife ® Fractions 614 N/A<br />
High-Dose-Rate Brachytherapy 157 N/A<br />
2010 Annual Cancer Report • 9
FOUNDATIONS OF CANCER CARE (con’t)<br />
The daVinci ® Robotic Surgical <strong>System</strong> is designed<br />
to enable complex surgery using a very precise,<br />
minimally invasive approach. We were the first<br />
Michigan hospital to routinely utilize the system for<br />
complex thoracic and cardiac surgery.<br />
Surgical Oncology<br />
The American College of Surgeons ranks SJMHS<br />
among the best cancer care providers in the United<br />
States. We have an expert team of respected and<br />
experienced oncologic surgeons, with each<br />
specialty trained to treat specific malignancies:<br />
° Thoracic/Esophageal Tumors<br />
° Breast Cancer<br />
° Neurological Cancers (Brain, Spinal Cord)<br />
° Genitourinary Cancers (Renal, Prostate)<br />
° Cutaneous Cancers (Skin)<br />
° Hepatobiliary Malignancies (Liver, Pancreas)<br />
° Colorectal Cancer<br />
° Gynecologic Malignancies<br />
In 2007, SJMHS opened one of the most sophisticated<br />
surgery pavilions in the country at St. <strong>Joseph</strong> <strong>Mercy</strong><br />
Hospital, Ann Arbor. The all-new, 60,000 square-foot<br />
facility features 17 suites designed for minimally<br />
invasive procedures and equipped with the latest<br />
computer, image-driven technology, including the<br />
daVinci ® Robotic Surgical <strong>System</strong>. This robotic<br />
platform is designed to enable complex surgery<br />
using a very precise, minimally invasive approach.<br />
We were the first Michigan hospital to routinely utilize<br />
the daVinci ® system for complex thoracic and<br />
cardiac surgery.<br />
Multidisciplinary Clinics<br />
The St. <strong>Joseph</strong> <strong>Mercy</strong> cancer program has dedicated<br />
clinic space on the second floor of the Cancer<br />
Center in Ann Arbor. This spacious suite incorporates<br />
patient exam rooms as well as well as patient/family<br />
meeting rooms and large conference spaces. Multidisciplinary<br />
clinics are in place for the following areas:<br />
° Lung cancer<br />
° Breast cancer<br />
° Head and neck malignancies<br />
° Neuro-oncology diagnoses<br />
° Gastrointestinal cancers<br />
° All diagnoses requiring CyberKnife ® treatment<br />
(both intracranial and extra-cranial malignancies)<br />
The lung cancer multidisciplinary clinic is our most<br />
experienced and long-standing clinic which serves<br />
as the model for all other multidisciplinary clinics.<br />
10 • 2010 Annual Cancer Report
Multidisciplinary Care<br />
The overriding model for cancer care at St. <strong>Joseph</strong><br />
<strong>Mercy</strong> Cancer Center is the interdisciplinary Advisory<br />
Committees that have been established for breast<br />
cancer, lung cancer, gastrointestinal malignancies,<br />
genitourinary tumors, neurologic malignancies,<br />
gynecologic oncology, and head/neck cancers.<br />
Advisory Committees are charged with the<br />
development and oversight of the overall program<br />
and service delivery for their diagnostic sites. National<br />
Comprehensive Cancer Network Guidelines<br />
(NCCN) provide the framework for care. Committee<br />
membership is comprised of key physicians, nurse<br />
navigators, research nurses, administrators, and social<br />
workers. The Advisory Committees are responsible<br />
for the ongoing evaluation of their programs and the<br />
implementation of quality initiatives. Each committee<br />
includes a Nurse Navigator, which is discussed in<br />
greater detail in this report in the section “Coordination<br />
of Care.”<br />
Breast Cancer Program<br />
Breast care at SJMH is delivered in a comprehensive<br />
multidisciplinary program including all sectors of care<br />
from screening through breast cancer survivorship.<br />
Screening is performed through an all digital network<br />
with diagnostics performed at the Women’s <strong>Health</strong><br />
Center at SJMH-Ann Arbor and our outpatient centers<br />
in Chelsea and Brighton. Over 50,000 mammograms<br />
are performed yearly and read the same day by<br />
radiologists specializing in breast diagnostics.<br />
In addition to digital mammography the centers<br />
are equipped with breast MRI capability for screening<br />
high-risk women and performing MRI-guided biopsies.<br />
A training program has been developed and implemented<br />
following American College of Radiology<br />
guidelines to ensure expert interpretation of MRI<br />
exams. New state-of-the-art ultrasound equipment<br />
for core biopsies and diagnostic studies has been<br />
acquired and is currently being utilized in both the<br />
Ann Arbor and Brighton centers.<br />
Breast <strong>Health</strong> Specialists and a Breast Cancer Nurse<br />
Navigator ensure the seamless delivery of care and<br />
provide patient education and support. Navigators<br />
meet patients at the time of breast biopsy to assess<br />
patient needs if the biopsy is positive. They provide<br />
education related to surveillance of high-risk<br />
conditions noted by Pathology.<br />
Radiation oncology offers the most technologically<br />
advanced planning and treatment systems,<br />
including partial breast irradiation. Nationally<br />
accepted guidelines are followed for cancer care.<br />
A database through the Michigan Breast Oncology<br />
Quality Initiative, the National Comprehensive<br />
Cancer Network, and Quality Oncology Physician<br />
Initiative funded through Blue Cross Blue Shield of<br />
Michigan provide nearly real-time quality data to<br />
help with benchmarking and ensure compliance<br />
with guidelines.<br />
An Image Recovery Center was recently<br />
opened in the beautiful Inspirit Salon & Spa<br />
located in the retail space of the new St.<br />
<strong>Joseph</strong> <strong>Mercy</strong> Hospital in Ann Arbor. Full-time<br />
image recovery services and products are<br />
offered including prosthesis fittings, skin care<br />
and clothing items specific to the needs of<br />
breast cancer patients, head shaving, wigs<br />
and head scarves. The certified specialist<br />
working in this center personally visits all<br />
patients hospitalized after breast cancer<br />
surgery to provide assistance and assure<br />
the patient is aware of available resources.<br />
2010 Annual Cancer Report • 11
FOUNDATIONS OF CANCER CARE (con’t)<br />
Gastrointestinal (GI) Cancer Program<br />
The Gastrointestinal Cancer Program has evolved<br />
to become one of the premiere cancer care<br />
programs at SJMHS, encompassing multiple<br />
physician specialists who are recognized experts in<br />
their fields and cutting edge technology offered by<br />
only a few centers in the state. The following<br />
provides a brief overview of some of the important<br />
work being done by this outstanding team.<br />
Over 16,000 endoscopies are performed each year.<br />
Our managed care colorectal screening rate is 68%<br />
compared with 59% for southeast Michigan.<br />
The Department of Colorectal Surgery comprised of<br />
three colorectal surgeons pioneered the technique<br />
of laparoscopic colectomy and are currently at the<br />
forefront of minimally invasive surgery using the<br />
daVinci ® robotic surgical system. Robert Cleary, MD,<br />
has achieved the distinction of becoming the<br />
leading robotic colorectal surgeon in the Midwest.<br />
Another new area of expertise utilized by the<br />
colorectal surgeons is transendoscopic microsurgery<br />
or TEM. TEM allows the minimally invasive local<br />
excision of rectal tumors with the aid of a special<br />
operative rectoscope and magnified view. This<br />
technique is not widely available due to the necessary<br />
special instrumentation, unusual technical aspects<br />
of the approach, and stringent patient selection.<br />
Dr. Cleary has led the effort at SJMH to establish a<br />
colorectal surgery fellowship program,<br />
and our first fellow is expected in<br />
July 2011.<br />
The scholarly work of Naresh Gunaratnam, MD, has<br />
focused on two new minimally invasive techniques<br />
to combat the potentially progressive disease of<br />
Barrett’s Esophagus with or without high-grade<br />
dysplasia. Radiofrequency ablation (BARRX) utilizes<br />
energy to allow a limited depth of injury to destroy<br />
the Barrett’s cells without destroying the normal tissue<br />
in the deeper layers. Endoscopic Mucosal<br />
Resection (EMR) is a procedure that is available<br />
for removal of small nodules within the Barrett’s<br />
segment. EMR enables physicians to take a much<br />
larger biopsy specimen and offers the advantages<br />
of outpatient treatment. Both Dr. Gunaratnam and<br />
his colleague, Dr. Andrew Catanzaro, have<br />
successfully performed the BARRX and/or EMR<br />
procedures on over 45 patients with Barrett’s<br />
related dysplasia and adenocarcinoma. To date,<br />
five patients have completed treatment and<br />
show no residual dysplasia or cancer with up<br />
to three-year follow-up.<br />
Edward Kreske, MD, specializes in surgery of liver,<br />
pancreas and gallbladder. Minimally invasive<br />
techniques include laparoscopic pancreatic<br />
surgical resections, radiofrequency ablation for<br />
treatment of hepatocellular carcinoma and<br />
embolization in conjunction with the expertise<br />
of the interventional radiologists.<br />
The GI Cancer Program was one of the first workgroups<br />
at SJMH to embrace multidisciplinary care,<br />
which is evident in their progress and the fact that<br />
they are in the forefront of their field.<br />
Robert Cleary, MD and the<br />
daVinci Robotic Surgical <strong>System</strong><br />
12 • 2010 Annual Cancer Report
Lung Cancer Program<br />
Genitourinary Cancer Program<br />
Although the Genitourinary Cancer Advisory<br />
Committee oversees care of patients with<br />
tumors of the entire genitourinary system, a<br />
major focus of their work is in the field of prostate<br />
cancer. The Committee includes specialists in<br />
urology, radiation oncology, medical oncology,<br />
radiology and pathology.<br />
Over the past year, this group has<br />
accomplished the following:<br />
° Adoption of the National Comprehensive<br />
Cancer Network (NCCN) prostate cancer<br />
treatment guidelines that assures patients are<br />
educated about all recommended treatment<br />
options and are afforded the opportunity to<br />
consult with all appropriate specialists;<br />
° Prostate biopsy protocols were reviewed and<br />
standardized so that core biopsies performed<br />
in both the Urology and Radiology<br />
Departments include twelve core samples<br />
done with local anesthesia;<br />
° Educational resources for prostate cancer<br />
patients were developed and made available<br />
throughout urology offices as well as radiation<br />
and medical oncology areas.<br />
The multidisciplinary team offers a full range of<br />
treatment options that include robotic-assisted<br />
surgeries, brachytherapy (high dose rate [HDR];<br />
low dose rate [LDR]); intensity modulated<br />
radiation therapy (IMRT), and hormonal therapy.<br />
Additionally, SJMHS is currently participating<br />
in a “Prospective Evaluation of CyberKnife ®<br />
Stereotactic Radiosurgery for Low and<br />
Intermediate Prostate Cancer: Homogenous<br />
Dose Distribution.”<br />
The SJMH Pathology Department added its<br />
first fellowship-trained genitourinary pathologist,<br />
Matthew Wasco, MD, who had the opportunity<br />
to spend some time at the University of Indiana<br />
studying testicular pathology.<br />
In addition, the SJMH Pathology Department<br />
now offers a relatively new laboratory test,<br />
Fluorescence in situ hybridization (FISH), to<br />
detect bladder cancer through analysis of<br />
chromosomal abnormalities in urine.<br />
Over the last few years, lung cancer treatment has<br />
transitioned toward minimally invasive techniques and<br />
expanding the role of robotic surgery. Additionally, the<br />
field of video-assisted thoracoscopic surgery (VATS)<br />
has evolved from experience with laparo-scopic<br />
procedures. Advanced video technology, computers<br />
and high-tech electronics are utilized to perform many<br />
operations that formerly required large, open incision<br />
thoracotomy.<br />
Other technologic advances are also changing the<br />
scope of lung cancer treatment. With the addition of<br />
the new Cyberknife ® , we are now able to offer curative<br />
therapy to those patients who are not good surgical<br />
candidates due to pulmonary function or other medical<br />
comorbidities. We have obtained the superDimension ®<br />
Electromagnetic Navigation Bronchoscopy system<br />
designed to extend the reach of the conventional<br />
bronchoscope, providing minimally invasive access to<br />
lesions deep in the lungs as well as mediastinal lymph<br />
nodes. Using GPS-like navigation, this system enables<br />
physicians to make early diagnoses of benign and<br />
malignant lung lesions.<br />
SJMHS is participating in an International Randomized<br />
Study to Compare CyberKnife® Stereotactic Radiotherapy<br />
with Surgical Resection in Stage I Non-Small<br />
Cell Lung Cancer (STARS). Sites from around the world<br />
are participating in this 1,200-patient study, with<br />
coordination and oversight by the MD Anderson<br />
Cancer Center team. In addition, we have developed<br />
a cryotherapy program that facilitates treatment<br />
of endobronchial tumors and maintenance of<br />
airway patency.<br />
The above describes cutting-edge approaches to lung<br />
cancer treatment. However, as we view the continuum<br />
of care, we are working diligently to develop initiatives<br />
that address the area of prevention. We are especially<br />
proud of a smoking cessation program that we are<br />
implementing in offices of primary care physicians<br />
called “Tackle Tobacco.” This program is based<br />
on the U.S. Department of <strong>Health</strong> and Human Services<br />
Clinical Practice Guidelines: Treating Tobacco Use<br />
and Dependence (2008), which provides an evidencebased<br />
framework. “Tackle Tobacco” is a system-wide<br />
“train the trainer” program in which an office<br />
“champion” is educated regarding tobacco addiction,<br />
“quit” products, motivational interviewing, methods/<br />
tools to assess smoking behaviors, and counseling<br />
strategies to assist patients to discontinue smoking.<br />
Office “champions” are also charged with the<br />
development of a plan to ensure compliance with<br />
this program in their office practices.<br />
Vita Sullivan, MD has been the Medical Director of Thoracic<br />
Oncology since 2006. Dr. Sullivan completed her medical<br />
education at the University of Chicago. She did her General<br />
Surgery Residency at St. <strong>Joseph</strong> <strong>Mercy</strong> Hospital, Ann Arbor,<br />
MI and her Fellowship in Cardiothoracic Surgery at the<br />
University of Minnesota, Minneapolis, MN.<br />
2010 Annual Cancer Report • 13
FOUNDATIONS OF CANCER CARE (con’t)<br />
Gynecologic Oncology Program<br />
Gynecologic oncology practice is joining with<br />
scientific experts to deliver minimally invasive surgery<br />
for staging of endometrial cancer. Robot-assisted<br />
surgery with the da Vinci ® Surgical <strong>System</strong> is<br />
accomplished by our surgeons through tiny, 1-2<br />
centimeter incisions; this provides greater precision<br />
and control, minimizing the pain and risk associated<br />
with large incisions while increasing the likelihood of<br />
a fast recovery and excellent clinical outcomes.<br />
Head & Neck Malignancies<br />
Head and neck tumors include those that arise in<br />
the nasal cavity, sinuses, lips, oral cavity, salivary<br />
glands, throat, or larynx. They comprise 3-5% of all<br />
cancers nationally, and average about 2% of all new<br />
cancer diagnoses at SJMH. The multidisciplinary<br />
team working with this patient population includes<br />
otolaryngologists, radiation oncologists, medical<br />
oncologists, plastic surgeons, pathologists, and<br />
speech therapists.<br />
Although not a new practice, intraperitoneal (IP)<br />
chemotherapy has become a standard of care<br />
for women fighting gynecologic cancers within the<br />
peritoneal cavity. Collaboration with our interventional<br />
radiologist for the insertion of abdominal ports for<br />
IP chemotherapy has eliminated the need for<br />
patients to return to the operating room following<br />
a diagnosis of cancer. This alliance has saved<br />
patients a surgical procedure and improved<br />
recovery time while allowing for an expedited<br />
initiation of IP chemotherapy.<br />
The gynecologic oncologists at SJMHS participate in<br />
national Gynecologic Oncology Group clinical trials<br />
through the Michigan Cancer Research Consortium<br />
CCOP. In addition, investigator-initiated studies are<br />
implemented when they are deemed appropriate<br />
for the SJMHS population. One such study currently<br />
underway surveys gynecologic oncology patients<br />
to measure distress during cancer treatment; results<br />
will be shared with oncology program physicians<br />
and staff.<br />
Neurologic Cancers (Brain, Spinal Cord)<br />
The advent of the CyberKnife ® has had a tremendous<br />
impact on the treatment of brain and spinal cord<br />
tumors. SJMH neurosurgeon Georffrey M. Thomas, MD,<br />
was the first neurosurgeon in Michigan to perform<br />
pain-free CyberKnife ® radiosurgery. Using this<br />
revolutionary technology, he is able to “target”<br />
benign and malignant tumors of the brain and spine<br />
with extreme accuracy. Having just completed our<br />
third year of treating patients with the CyberKnife ® ,<br />
data show that for brain and spine cases we have<br />
treated 13 malignant and 36 non-malignant tumors.<br />
The head and neck surgeons at St. <strong>Joseph</strong> <strong>Mercy</strong><br />
Hospital in Ann Arbor are among the first in the<br />
country to offer Trans-Oral Robotic Surgery (TORS)<br />
for their patients. TORS is a minimally invasive<br />
surgical treatment for diseases of the head and<br />
neck. The robotic instruments provide the surgeon<br />
with unsurpassed visualization, precision, dexterity<br />
and control. For head and neck cancer surgery,<br />
the advantages are much faster recovery, decreased<br />
need for feeding tubes, and no scar. TORS is FDA<br />
approved for excision of tumors of the tongue,<br />
tonsils and larynx (voice box). Potential benefits<br />
of TORS include the avoidance of disfiguring surgery,<br />
minimizing or eliminating the need for chemotherapy<br />
or radiation therapy, avoiding tracheotomy, quicker<br />
return to normal speech and swallowing, less pain,<br />
shorter recovery time, and minimal scarring.<br />
Endocrine Cancers (Thyroid)<br />
The major focus of the Endocrine Cancers Advisory<br />
Committee has been in the area of the diagnosis<br />
and treatment of thyroid cancer. The Committee<br />
has standardized treatment guidelines for thyroid<br />
cancers. Of importance has been their work to<br />
correlate the fine needle aspiration biopsy results<br />
with the subsequent surgical outcomes, ensuring<br />
that the pre-surgical biopsy results correlate with<br />
the surgical pathology; results have been excellent,<br />
with no false positive results.<br />
Of note is the increased utilization of Thyrogen<br />
scanning (and treatment as applicable) in patients<br />
with certain types of thyroid cancer. The use of<br />
Thyrogen is an alternative to thyroid hormone<br />
withdrawal and is more convenient for patients.<br />
14 • 2010 Annual Cancer Report
Skin Cancers (Melanoma)<br />
The Academic Dermatology Residency is in its fifth<br />
year. We currently have 11 residents in our three-year<br />
program. All have presented at national meetings<br />
including the American Academy of Dermatology.<br />
SJMH medical staff dermatologists and dermatology<br />
residency dermatologists remove hundreds of skin<br />
cancers per year including both melanoma and<br />
non-melanoma lesions (squamous cell carcinomas<br />
and basal cell carcinomas).<br />
Cutaneous T Cell lymphoma patients are cared for<br />
by Dr. David Fivenson.<br />
Areas of research over the past two years include<br />
new TMN (tumor-metastases-node) and pathologic<br />
classification of malignant melanoma as well as new<br />
protocols for treatment of melanoma and Merkel<br />
cell carcinoma.<br />
The focus of the cutaneous malignancy program<br />
has been on establishing state-of-the-art care<br />
for individuals with various skin cancers. Key<br />
accomplishments in this area include implementation<br />
of a Mohs Micrographic Surgery clinic at SJMH<br />
and the development of sentinel node testing for<br />
malignant melanoma. Close collaboration between<br />
the dermatopathologists and plastic surgeons<br />
has resulted in excellent cure rates and minimum<br />
disfiguration for non-melanoma skin cancers<br />
using frozen section control to treat the malignancies.<br />
Mohs surgery for non-melanoma skin cancers is<br />
performed by three Mohs surgeons on the SJMH<br />
staff: Drs. Craig Cattell, Montgomery Gillard and<br />
Kent Krach. The sentinel lymph node biopsy program<br />
for advanced melanomas is expanding at SJMH<br />
with the addition of Dr. Ian Lytle, plastic surgeon;<br />
he is performing sentinel lymph node biopsies<br />
on deeper melanoma cases.<br />
Our second annual free skin cancer<br />
screening at SJMH was held in<br />
May 2010, with screening of over<br />
100 individuals. Both melanoma<br />
and non-melanoma skin cancers<br />
were detected in participants.}<br />
2010 Annual Cancer Report • 15
CANCER RESEARCH<br />
Michigan Cancer Research Consortium<br />
Community Clinical Oncology Program<br />
Since its inception in 1983, the Community Clinical<br />
Oncology Program (CCOP) of the National Cancer<br />
Institute has linked community cancer specialists to<br />
NCI-supported research to conduct approved<br />
cancer treatment, prevention, and control clinical<br />
trials. Types of studies carried out have broadened<br />
from treatment to chemoprevention, symptom<br />
management, continuing care, and quality of life.<br />
By far, the majority of cancer care is provided in the<br />
community setting; therefore, it is imperative that<br />
those patients and families have access to the most<br />
current and innovative treatment that is available<br />
through clinical trials programs. To this end, the<br />
oncology program at SJMHS initiated its research<br />
program in 1988.<br />
St. <strong>Joseph</strong> <strong>Mercy</strong> <strong>Health</strong> <strong>System</strong> first received<br />
funding for its clinical trials program from the<br />
National Cancer Institute in 1994 and has been<br />
funded continuously since that time. Originally<br />
established as the Ann Arbor Regional CCOP, its<br />
growth has been phenomenal under the steadfast<br />
leadership of Philip J. Stella, MD, principal<br />
investigator since the program’s inception. A name<br />
change better reflected its expansion to include its<br />
current 12 Michigan hospitals and one Connecticut<br />
hospital as well as over 100 medical oncologists,<br />
radiation oncologists, surgeons and other specialists.<br />
The MCRC CCOP received over $1.5 million in<br />
funding support in 2009 to maintain the infrastructure<br />
necessary to implement one of the country’slargest<br />
and most respected community research programs.<br />
The dollars support over 20 research staff of nurses,<br />
regulatory specialists, data managers, laboratory<br />
coordinators, a research pharmacist and program<br />
accountant.<br />
As one of 47 CCOP research programs currently<br />
sponsored by the NCI, the MCRC-CCOP has<br />
established a stellar reputation for quality research<br />
practices and patient accrual.<br />
The following highlights key accomplishments:<br />
° The MCRC-CCOP has received over $15 million in<br />
grant support from the NCI since 1994;<br />
° At any given time, over 120 treatment and cancer<br />
control studies are open and available for patient<br />
accrual;<br />
° Over 600 patients are placed on clinical trials<br />
each year, with SJMH patients comprising half of<br />
that total;<br />
° At any given time over 2,000 patients are being<br />
followed on protocols to which they were enrolled<br />
in previous years (e.g., long-term follow-up);<br />
° The MCRC CCOP received the prestigious<br />
American Society of Clinical Oncology Clinical<br />
Trials Participation Award (2006) for its demonstrated<br />
outstanding “commitment to improving the care<br />
of people with cancer through increased<br />
participation in clinical trials.”<br />
16 • 2010 Annual Cancer Report
CARE ACROSS<br />
THE CONTINUUM<br />
National Cancer Institute Community<br />
Cancer Centers Grant (NCCCP)<br />
In 2009, SJMHS applied for and received the<br />
prestigious NCI Community Cancer Centers<br />
Program (NCCCP) grant with funding of $2.5 million<br />
over two years. This grant program is competitive,<br />
and SJMHS was among only 14 sites selected from<br />
applications across the country. This program is a<br />
strategic partnership of the NCI and participating<br />
hospitals designed to create a community-based<br />
cancer center network to support cancer research<br />
and enhance access to quality care at community<br />
hospitals. It began as a pilot program in 2007 as a<br />
network of community hospital cancer centers<br />
working to provide the most current, researchbased<br />
cancer care spanning the full cancer<br />
continuum with an emphasis on minority and<br />
underserved populations.<br />
Funding for this program comes from the American<br />
Recovery and Reinvestment Act and, therefore, will<br />
support the hiring of individuals to address the<br />
seven major focus areas designed to:<br />
° Reduce cancer health disparities<br />
° Improve quality of care at community hospitals<br />
° Increase participation in clinical trials<br />
° Enhance cancer survivorship and palliative<br />
care services<br />
° Participate in biospecimen research initiatives to<br />
support personalized medicine<br />
Nurse Navigators<br />
The Nurse Navigator role has existed at St. <strong>Joseph</strong><br />
<strong>Mercy</strong> Cancer Care Center for over ten years.<br />
Initial collaboration with the Women’s <strong>Health</strong><br />
Program supported the hiring of a nurse navigator<br />
for our breast cancer population. Being at<br />
the forefront of this concept, we needed to<br />
demonstrate the value of this role to physicians<br />
who believed their office staff provided all of the<br />
assistance required by women with breast cancer.<br />
However, patients readily embraced the direction,<br />
information and support offered by the nurse<br />
navigator as they traversed the health care system.<br />
Today there is no question as to the invaluable<br />
role nurse navigators play in the oncology field.<br />
In spring 2009, the Michigan Cancer Research<br />
Consortium CCOP applied for and received<br />
Administrative Supplement funding under the<br />
American Recovery and Reinvestment Act (2009)<br />
for the hiring of an Oncology Research Nurse<br />
Navigator (ORNN). The ORNN links with<br />
all newly-diagnosed patients to facilitate their<br />
transition to treatment with an important focus<br />
on considering a treatment plan that incorporates<br />
clinical trials.<br />
With the NCCCP award, the Office of Nurse<br />
Navigators was formalized in fall 2009 and is now<br />
comprised of four full-time and one part-time<br />
nurse navigator who work with all of the surgeons,<br />
medical oncologists and radiation oncologists so<br />
that all patients are contacted shortly after they<br />
are notified by their physician of their cancer<br />
diagnoses.<br />
° Expand use of electronic health records and<br />
connect to cancer research data network<br />
° Enhance cancer advocacy<br />
<strong>Saint</strong> <strong>Joseph</strong> <strong>Mercy</strong> <strong>Health</strong> <strong>System</strong><br />
clinical nurse navigators that assist<br />
our patients through oncology<br />
services: left to right – Lara Blair,<br />
Pam Ceo, Sharon Petri, Colleen<br />
Sweetland and Jennifer Bailey.<br />
2010 Annual Cancer Report • 17
CARE ACROSS THE CONTINUUM (con’t)<br />
Community Partnerships<br />
Both the American Cancer Society (ACS) and The<br />
Wellness Community have a major presence in our<br />
community. Our 25-year relationship with the<br />
American Cancer Society covers a broad spectrum<br />
of involvement including ACS community and state<br />
Board representation by SJMHS oncologists, Cancer<br />
Center administrators, and social workers; long-term<br />
(20+ years) collaboration in the presentation of<br />
patient support programs including “Look Good . . .<br />
Feel Better;” co-sponsoring of survivor events such<br />
as “Making Strides Against Breast Cancer;” and<br />
participation in fundraising activities.<br />
Our current partnership with ACS extends to<br />
implementation of the ACS Cancer Resource<br />
Centers at both the Ann Arbor and Brighton cancer<br />
centers. ACS volunteers work with patients at these<br />
facilities to assess needs that can be met through<br />
ACS resources. This has resulted in over 518 referrals<br />
for ACS services in 2009. SJMHS is the most involved<br />
and active health system in partnership with the ACS<br />
in southeastern Michigan.<br />
SJMHS is committed to “walk the talk” when it<br />
comes to working with community agencies for the<br />
benefit of oncology patients and families. To that<br />
end, SJMHS has made the commitment to donate<br />
land on its 341-acre campus for the construction<br />
of an American Cancer Society Hope Lodge.<br />
Hope Lodge offers free lodging for patients and<br />
caregivers who live outside the area and are<br />
receiving treatments or undergoing clinical trials<br />
at SJMHS. ACS is currently developing its timeline<br />
for this important project.<br />
Over the past three years, The Wellness Community<br />
of Southeast Michigan has become the major<br />
provider in our service area of support and<br />
educational services for cancer patients, families,<br />
and friends. All services are free for participants.<br />
Located in Ann Arbor, MI, it began as a grass roots<br />
organization that was started locally by a group of<br />
committed community volunteers who were each<br />
personally touched by cancer. Linda Langmore,<br />
MSW, oncology social worker in the St. <strong>Joseph</strong><br />
<strong>Mercy</strong> Cancer Center, was one of the organization’s<br />
founding members.<br />
The Wellness Community offers a comprehensive<br />
array of educational programs and workshops which<br />
are often provided by SJMHS oncologists, nurses, and<br />
other health care providers. For example, a class<br />
entitled “Frankly Speaking About Advanced Breast<br />
Cancer” was presented in October 2009 by Elaine<br />
Chottiner, MD, medical oncologist at SJMHS. Wellness<br />
Community brochures and events calendars are<br />
placed in the waiting rooms of all cancer center<br />
departments as well as physician offices.<br />
<strong>Health</strong> Disparities<br />
We will have no difficulty directing almost 40% of<br />
NCCCP project funding to disparities initiatives.<br />
An NCCCP award allows us to build on the successes<br />
we have had by:<br />
° Hiring a Manager of the <strong>Health</strong>care Disparities<br />
Program whose sole focus is the planning,<br />
implementation and evaluation of a cancerfocused<br />
program addressing the myriad of needs<br />
of patients and families who comprise minority,<br />
underserved, and uninsured persons.<br />
° Expanding our social services programs and<br />
staff to focus on the needs of minority and socioeconomically<br />
disadvantaged patients and<br />
families;<br />
° Enlisting a dedicated oncology patient financial<br />
services counselor to work with our<br />
socioeconomically disadvantaged population;<br />
° Expanding our network of African-American<br />
churches in the SJMH service area;<br />
° Initiating linkages with area churches that are<br />
building their Hispanic congregations (e.g., First<br />
United Methodist Church, Ypsilanti, MI; St. Mary’s<br />
Student Chapel, Ann Arbor, MI);<br />
° Establishing linkages with the ever-growing Asian<br />
populations in Washtenaw and Wayne Counties;<br />
° Expanding the MCRC CCOP’s minority-directed<br />
community education programs related to the<br />
NCI clinical trials program.<br />
18 • 2010 Annual Cancer Report
Biospecimen Research Initiatives<br />
The NCCCP award allows us to make significant<br />
progress toward the implementation of the NCI Best<br />
Practices for Biospecimen Resources program. We<br />
have the full support of Samuel Hirsch, MD, Chief<br />
of Pathology, and Drs. Paul Valenstein and <strong>Joseph</strong><br />
Tworek who have assumed responsibility for this<br />
project. Our experience in the collection and<br />
submission of both blood and tissue samples is<br />
significant through our clinical trials program. Many<br />
NCI clinical trials require specimen collection; other<br />
studies offer pharmacodynamic and pharmacokinetic<br />
testing as optional. The Michigan Cancer<br />
Research Consortium CCOP’s participation in these<br />
optional studies approaches 98%, establishing the<br />
framework for SJMHS leadership in the Biospecimen<br />
Research Initiative.<br />
Our work in the area of biospecimen research is<br />
a component of the National Cancer Institute’s<br />
Translational Research Program. The mission of<br />
the Translational Research Program is to integrate<br />
scientific advancements in the understanding of the<br />
biology of human cancer with the development of<br />
new interventions for the prevention, diagnosis, and<br />
treatment of cancer patients or populations at risk<br />
for cancer – and to speed up the process in order<br />
that promising new cancer discoveries can be<br />
translated into new interventions for patients faster.<br />
This is a particularly critical element for the future<br />
of oncology care and one to which we are<br />
strongly committed.<br />
Cancer Survivorship and<br />
Palliative Care Services<br />
Palliative Care is an approach to health care<br />
that focuses on relief of suffering and symptom<br />
management rather than on curing disease. It is<br />
designed to help provide the highest quality of<br />
life possible for people with illnesses that cannot be<br />
cured or conditions that are life-limiting. The Palliative<br />
Care Program at SJMH is staffed by a team of<br />
physicians, nurses, social workers, and pastoral care<br />
professionals, all skilled in symptom management<br />
and end-of-life care. They assist in the design and<br />
implementation of comprehensive care plans that<br />
include all aspects of patients’ and families’<br />
needs at this very critical time.<br />
The SJMHS oncology program developed a<br />
role which spans the entire continuum from the<br />
outpatient infusion area and inpatient units to the<br />
patients’ homes. Chaplain David McNeil has defined<br />
the continuum of care to mean any and all places<br />
where patients and families exist. He goes wherever<br />
needed. Home visits are common. He is often at<br />
the bedside when a patient dies. Chaplain McNeil<br />
performed numerous funeral services in the past<br />
year for those patients without a church home.<br />
We are fortunate to have this role and a remarkable<br />
man to fill it who embodies the word “continuum”<br />
as no other has done.<br />
Chaplain David McNeil has defined the<br />
continuum of care to mean any and all<br />
places where patients and families exist.<br />
He goes wherever needed.<br />
2010 Annual Cancer Report • 19
PATIENT CENTEREDNESS<br />
Oncology Patient Advocates Team<br />
Initiated in June 2008, the Oncology Patient Advocates<br />
Team links with cancer center patients and families<br />
to develop and implement plans to enhance the<br />
patient experience at SJMHS. Membership on this<br />
important workgroup includes staff from most<br />
disciplines, representatives from community<br />
organizations, and oncology patients and<br />
families. Key projects over the past year include:<br />
Implementation of patient support, advocacy and<br />
information symposia during both Cancer Survivors’<br />
Month and Lung Cancer Awareness Month. These<br />
events were jointly sponsored by SJMHS, Wellness<br />
Community, and American Cancer Society.<br />
Patient Satisfaction<br />
A critical component of our quality management<br />
plan is the measurement of how satisfied patients<br />
are with the care we provide. Quarterly surveys are<br />
undertaken for SJMH inpatient areas. One of the<br />
most revealing questions asked relates to whether<br />
the individual patient would recommend the hospital<br />
to family. Results from the most recent survey<br />
conducted during the last quarter of 2009 were<br />
extremely positive for the inpatient oncology unit<br />
at SJMH. Patients rated the hospital in general in the<br />
top decile of the survey respondents. As to whether<br />
oncology patients would recommend the hospital<br />
to family, 83% responded in the affirmative, which,<br />
again, was in the top decile of those responding.<br />
Development of an atmosphere of camaraderie<br />
and sharing in our cancer treatment centers through<br />
activities such as barbeques, musical performances,<br />
and holiday events.<br />
Expansion of the American Cancer Society’s<br />
Resource Center volunteers who align with cancer<br />
program staff to provide patients with information<br />
regarding available resources.<br />
In addition, the Oncology Patient Advocates<br />
Committee appointed a Survivorship Support Team.<br />
The Survivorship Support Team is in the process of<br />
obtaining patient feedback regarding survivorship<br />
issues and is charged with the task of developing<br />
survivorship care plans. A representative from the<br />
Wellness Community is a member of this workgroup<br />
and will provide leadership for this process.<br />
Radiation Oncology has an ongoing patient<br />
satisfaction survey program which includes specifics<br />
to their department (e.g., satisfaction with radiation<br />
schedule, courtesy of staff, etc.). Other components<br />
of the oncology program survey patients and family<br />
members periodically as well as solicit feedback at<br />
all points in their care.<br />
A Patient Speaks<br />
Following is a letter received from a patient written<br />
to Phil Stella, MD, Medical Director of the SJMHS cancer<br />
program. The perspective of this gentlemen is unique,<br />
as he is also a retired physician who was on the SJMHS<br />
staff for more than 35 years. As an internist, he was<br />
particularly interested in and aware of many aspects<br />
of care not evident to most patients entering our doors.<br />
His experience is what we strive for . . . and why the<br />
hundreds of our cancer program physicians and<br />
team members come to work every day.<br />
20 • 2010 Annual Cancer Report
Dear Phil:<br />
Imagine my surprise when what originally was thought to be a rather large<br />
hematoma over my sternum turned out to be a malignancy, hurling me over<br />
to a most uncomfortable position of being a patient -- and a cancer patient<br />
at that! I never thought about “needing” you and your colleagues, being<br />
only desirous of a collegial and social relationship. However, I wanted to<br />
share a few thoughts about my experience, particularly as it relates to what<br />
we all speak so casually about as the “continuum of care.”<br />
First, the diagnostic process was relatively easy. A quick ultrasound and<br />
then an appointment with the surgeon who set me up for a C-T the same<br />
afternoon. Outpatient surgery was readily scheduled to accommodate my<br />
calendar. Then things got interesting. The frozen section was reported to<br />
be a sarcoma.<br />
Over the following week, extraordinary efforts were made on my behalf. The<br />
surgeon arranged for me to see the oncologic surgeon at the University of<br />
Michigan. The pathologists collaborated with their colleagues at U of M to<br />
determine the definitive diagnosis for a somewhat unusual tumor specimen.<br />
To our amazement and relief, a final diagnosis of T-cell lymphoma was<br />
made – a totally curable malignancy which required tried and true<br />
CHOP chemotherapy. I then moved into the medical oncology realm and<br />
appreciated the care and thoughtfulness of Andy Eisenberg, MD, who even<br />
provided me with a thorough literature review of T-cell lymphomas!<br />
Care in the oncology infusion clinic was extraordinary – there’s no other<br />
way to describe it. The expertise and competency of the nursing staff was<br />
apparent. Follow-up required PET scans at 3- and 6-month intervals,<br />
which were scheduled at the time of my visits with Andy.<br />
As I moved through the cancer experience, interacting with multiple<br />
departments (radiology, surgery, pathology, laboratory, medical oncology,<br />
chemotherapy infusion, pharmacy) and cancer center staff, your years<br />
of work to develop a cohesive approach to cancer care was evident –<br />
and I am one grateful patient.<br />
With best regards,<br />
Gerry<br />
2010 Annual Cancer Report • 21
QUALITY INITIATIVES AND OUTCOMES<br />
The SJMHS cancer program is accredited by the<br />
American College of Surgeons’ Commission on<br />
Cancer as a Teaching Hospital Cancer Program.<br />
As such, it is held to the standards of this organization<br />
and must undergo rigorous on-site reviews every<br />
three years.<br />
In 1993, our measurements related to the quality of<br />
care we were providing utilized data from our Tumor<br />
Registry and compared our data with that of other hospital<br />
tumor registries. We were able to review such<br />
things as stage of disease at diagnosis, numbers of patients<br />
enrolling in clinical trials, and morbidity and mortality<br />
data. Over the years we have chosen to participate<br />
in the multiple cancer quality databases available<br />
so as to develop one of the most comprehensive<br />
and far-reaching quality programs in existence today.<br />
These databases include the National Comprehensive<br />
Cancer Network (NCCN) Breast Cancer Database, the<br />
Quality Oncology Physician Initiative (QOPI) sponsored<br />
by the American Society of Clinical Oncology (ASCO),<br />
the Society of Thoracic Surgeons (STS) Database, the<br />
Blue Cross & Blue Shield of Michigan Pathways Project,<br />
and the American College of Surgeons Tumor Registry.<br />
We clearly want to know how our care compares with<br />
that around the country, and “continuous improvement”<br />
is a framework which we embrace.<br />
We are pleased to provide an overview of some of the<br />
quality initiatives that have been accomplished as well<br />
as those that are ongoing.<br />
Oncology & Infusion Collaborative Practice<br />
Team: Review of Chemotherapy Safety<br />
Chemotherapy ordering has been identified as one<br />
of the most complex and potentially dangerous areas<br />
of medicine. Oncology practices and departments<br />
must employ strategies to ensure safety. To this end,<br />
the chemotherapy infusion staff initiated an ongoing<br />
review of “near misses” and chemotherapy errors in<br />
2009, reported via the PEERS (Potential Error/Event<br />
Reporting <strong>System</strong>) process. An Oncology & Infusion<br />
Collaborative Practice Team was established to<br />
oversee this project, and the Hematology/Oncology<br />
Section of the Department of Internal Medicine also<br />
reviewed the data; these two groups worked together<br />
to identify potential for improvement through process<br />
change, staff education and communication. The<br />
table illustrates an outstanding record of chemotherapy<br />
safety at SJMHS.<br />
Although the results are excellent, the Oncology &<br />
Infusion Collaborative Practice Team has developed<br />
standardized chemotherapy order forms as a process<br />
improvement project which will prevent any errors<br />
related to illegible orders.<br />
In addition, the Oncology & Infusion Collaborative<br />
Practice Team reviewed the 2009 Standards for<br />
Excellence in Chemotherapy Administration released<br />
by the American Society of Clinical Oncology and<br />
the Oncology Nursing Society and will be monitoring<br />
their practices to ensure compliance.<br />
2009 Data: Oncology<br />
Error / Near Miss<br />
Number (n)<br />
% of Doses<br />
Number of Errors/Near Misses/Events Reported 33 0.2%<br />
Number of chemotherapy doses given 16,000<br />
• Errors reached patient 17 0.1%<br />
• Unavoidable Events 2 0.0%<br />
• Near Misses 13 0.1%<br />
• Other (non-patient) 1 0.0%<br />
Error/Near Miss Resulted in Treatment Delay 3 0.02%<br />
Error/Near Miss Resulted in Significant Patient Harm 0 0.0%<br />
Extravasation (non-vesicant)/IV dislodgement 2 0.01%<br />
Extravasation (vesicant) 0 0.0%<br />
Avoidable Errors with Computerized Physician Order Entry 12 36.4%<br />
Related to Pump Programming/Pump Double Check 5 15.2%<br />
22 • 2010 Annual Cancer Report
Streamlining <strong>System</strong>s: Chemotherapy<br />
Order Processes<br />
Six Sigma originated as a set of quality management<br />
methods designed to improve manufacturing<br />
processes and eliminate defects, but its application<br />
was subsequently extended to other types of business<br />
processes as well. In Six Sigma, a defect is defined<br />
as any process output that does not meet customer<br />
specifications or that could lead to an output that<br />
does not meet customer specifications. Each Six<br />
Sigma project carried out within an organization<br />
follows a defined sequence of steps and has<br />
quantified targets.<br />
The staff in the Chemotherapy Infusion Clinic<br />
applied the Six Sigma Lean Process to streamline<br />
the chemotherapy order process so that orders were<br />
complete and available to both the pharmacist and<br />
charge nurse for review prior to a patient’s arrival,<br />
thereby ensuring that patients would have their<br />
chemotherapy initiated at their scheduled appointment<br />
time. Assessment of the “defects” or processes<br />
interfering with the desired “output” or goal determined<br />
two critical areas: (1) timing of patient’s laboratory<br />
studies, and (2) processing of chemotherapy orders.<br />
Findings showed that most patients were having their<br />
blood drawn immediately before treatment which<br />
delayed the initiation of chemotherapy and that 10%<br />
of chemotherapy orders required modifications.<br />
New processes were designed which required patients<br />
to have their blood work done at least two hours (and<br />
up to two days) prior to treatment. Chemotherapy<br />
orders are now written 2-5 days before treatment<br />
and submitted to the pharmacy and infusion clinic<br />
by mid-afternoon the day before treatment to allow<br />
the pharmacist and charge nurse to perform a<br />
preliminary review. These changes have resulted<br />
in significant improvements in the efficiency of<br />
chemotherapy schedules and administration.<br />
Streamlining <strong>System</strong>s: Radiation Oncology<br />
The Department of Radiation Oncology utilized the<br />
Six Sigma process to accomplish five goals:<br />
(1) Redesign of the registration process for better<br />
utilization of clerical staff and improved accuracy<br />
of information;<br />
(2) Redesign of the scheduling process to improve<br />
integration of staff and standardization of<br />
patient-centered care;<br />
(3) Redesign of the RN and Clerk roles to better<br />
utilize skills and improve time management of<br />
staff;<br />
(4) Redesign the DosSimulation planning process to<br />
allow more timely and efficient completion of<br />
treatment planning; and<br />
(5) Become a paperless department through<br />
implementation of the electronic medical record.<br />
Although a major undertaking, these quality<br />
improvement efforts were all accomplished over<br />
the course of four months with an added outcome<br />
of going entirely “paperless” when the new SJMHS<br />
Canton Cancer Center opened in November 2009.<br />
Cardiothoracic Surgery: Benchmarking<br />
Through the Society of Thoracic Surgeons<br />
Database<br />
The Society of Thoracic Surgeons began data<br />
collections for cardiac procedures in 1992 and<br />
for thoracic surgery in 2002. SJMHS cardiothoracic<br />
surgeons began contributing to the STS database<br />
in July 2006 when approximately 50 sites were<br />
participating; as of October 2009 there were 142<br />
sites collecting thoracic surgery data and 985 sites<br />
contributing cardiac surgery data.<br />
Utilizing the STS data for 2006-2009 as a benchmark,<br />
the Cardiovascular & Thoracic Surgeons of Ann<br />
Arbor completed a comprehensive study of thoracic<br />
surgery outcomes for that timeframe. They reviewed<br />
data from both open thoracotomies and video-assisted<br />
thoracic surgeries (VATS) with specific interest<br />
in lobectomy and pneumonectomy procedures.<br />
From that they developed/refined length-of-stay<br />
risk models. Patient profiles were consistent with<br />
STS data, and mortality was somewhat better<br />
(1.2% versus 1.6%).<br />
2010 Annual Cancer Report • 23
QUALITY INITIATIVES AND OUTCOMES (con’t)<br />
Medical Oncology: Quality Oncology<br />
Practice Initiative (QOPI)<br />
Ann Arbor Hematology Oncology Associates, the<br />
largest medical oncology private practice at SJMHS,<br />
is participating in the American Society of Clinical<br />
Oncology’s (ASCO) Quality Oncology Practice<br />
Initiative (QOPI). QOPI is one of a series of quality<br />
improvement initiatives underway between Blue<br />
Cross Blue Shield of Michigan, hospitals, and/or<br />
physician groups. QOPI is a physician-led voluntary<br />
program for measuring practice quality whose goal<br />
is to promote excellence in cancer care by assisting<br />
practices in creating a culture of self-examination<br />
and improvement. The oncologists at SJMHS submit<br />
information to ASCO’s national database on<br />
chemotherapy planning, chemotherapy-related<br />
side effects, pain assessment and control, and<br />
specific measures related to the management of<br />
oncology patients and end-of-life care. Blue Cross<br />
Blue Shield of Michigan (BCBSM) is providing funding<br />
to defray data collection costs and to encourage<br />
physician participation. Dr. Stella and Beth<br />
LaVasseur, RN, MSN were instrumental in working<br />
with BCBSM to implement this statewide.<br />
Medical Oncology: Michigan Oncology<br />
Clinical Treatment Pathways Program<br />
The SJMHS medical oncologists are also participating<br />
in the Michigan Oncology Clinical Treatment Pathways<br />
Program, a partnership between Blue Cross Blue<br />
Shield of Michigan, the Michigan oncology community<br />
and P4 <strong>Health</strong>care, an oncology benefit management<br />
company. Participating oncologists utilize oncology<br />
clinical pathways guidelines created by a steering<br />
committee of Michigan oncologists representing the<br />
most up-to-date and effective treatments for cancer<br />
patients. Objectives of the program include:<br />
° Establish evidence-based oncology treatment<br />
pathways for a variety of cancers, specifically<br />
with regard to the use of chemotherapy and<br />
supportive care<br />
° Define optimal quality care and treatment with<br />
the least toxicity while being most cost effective<br />
for the patient, provider, and payer – without<br />
compromising integrity or delivery of treatment<br />
° Decrease variability in treatment regimens between<br />
providers in order to utilize a consistent<br />
treatment regimen based upon a balance between<br />
outcomes, toxicity, and cost<br />
° Improve quality of health care delivery<br />
Initial results have demonstrated less variability<br />
in regimens, reduced misuse of chemotherapy,<br />
better managed toxicity, and more defined<br />
treatment milestones.<br />
Breast Program Quality Initiatives<br />
Nationally accepted guidelines are utilized to evaluate<br />
breast cancer care. A database through the<br />
Blue Cross funded Michigan Breast Oncology Quality<br />
Initiative (MiBOQI) and Quality Oncology Physician<br />
Initiative (QOPI) provides nearly real-time quality<br />
data to assist with benchmarking and ensure compliance<br />
with national guidelines.<br />
Breast program quality metrics for 2009 include:<br />
° The Breast Cancer Multidisciplinary Committee<br />
reviewed all MiBOQI data and chose to investigate<br />
two elements of patient cases that were considered<br />
non-concordant with NCCN Guidelines; these<br />
areas were:<br />
– Stage II, Node Positive Breast Cancer receiving<br />
chemotherapy; 67% of 57 evaluable patients<br />
received chemotherapy;<br />
– Sentinel Node Positive patients receiving axillary<br />
lymph node dissection; 71% of 66 evaluable<br />
patients were concordant.<br />
Each non-concordant patient case was reviewed<br />
and found to have well-documented rationale for<br />
non-compliance.<br />
° Thirteen key Breast Cancer Quality Measures were<br />
reviewed in the most recently diagnosed patients<br />
through the QOPI project at two sampling periods<br />
in 2009. Care measures were consistent with or<br />
demonstrated higher compliance in 12 of the 13<br />
measures. Cases that were non-concordant with<br />
standards were assessed and measures identified<br />
to correct non-compliance where applicable.<br />
24 • 2010 Annual Cancer Report
° The Breast Center undertook a quality improvement<br />
project to decrease the time from request for<br />
screening mammogram appointment to actual<br />
date of screening. In early 2009 the wait time was<br />
14 weeks; this was decreased to same week<br />
scheduling at the time of this report.<br />
° The number of positive biopsies as compared to<br />
number of biopsies completed is continuously<br />
monitored. Our rate of positive biopsies consistently<br />
measures ± 40% which is in keeping with<br />
national standards.<br />
Of key importance is the dedication of SJMH physicians<br />
to ongoing quality improvement. Tari Stull, MD,<br />
member of the Breast Cancer Advisory Committee,<br />
participated in the American Society of Breast<br />
Surgeons’ Mastery of Breast Surgery Pilot Program,<br />
a continuing quality improvement initiative. The<br />
program required a self-reporting process related<br />
to breast surgical procedures for both benign and<br />
malignant disease as a fundamental first step in<br />
improving quality. Ongoing continuing medical<br />
education criteria must be met over the ensuing<br />
five years to continue to meet the requirements of<br />
this program. In addition, Dr. Stull is presently<br />
completing a breast surgery fellowship at Bryn<br />
Mawr Hospital in Bryn Mawr, PA.<br />
Cancer Research Audits (2009-2010)<br />
The Michigan Cancer Research Consortium CCOP<br />
is affiliated with ten National Cancer Institute sponsored<br />
research bases (including the NCI Cancer Trials<br />
Support Unit). Each of these organizations conducts<br />
regularly-scheduled audits of data submitted for<br />
patients on clinical trials. Compliance with the<br />
exacting data requirements of clinical research is a<br />
strength of the MCRC. Over our 17-year history, the<br />
MCRC has established an excellent record for data<br />
quality and timeliness of submissions.<br />
The volume and detail of data submission is truly<br />
phenomenal. Over 120 studies were open for<br />
recruitment in 2009, and more than 1,300 patients<br />
have been enrolled in clinical trials in the past five<br />
years. On-site audits were conducted by the North<br />
Central Cancer Treatment Group (at Mayo Clinic),<br />
the Southwest Oncology Group, and the M.D.<br />
Anderson Cancer Center with excellent results.<br />
American College of Surgeons’ Commission<br />
on Cancer: Outcomes Comparison<br />
The SJMH Cancer Program is accredited by the<br />
American College of Surgeons’ Commission on<br />
Cancer as a Teaching Hospital Cancer Program.<br />
The standards “ensure that cancer services, care,<br />
and patient outcomes are evaluated and improved<br />
so that patients receive care that meets or exceeds<br />
patient expectations and standards distributed by<br />
local, state, regional, and national standard-setting<br />
organizations.” This requires an annual evaluation<br />
of services and care which provides a baseline to<br />
measure quality and an opportunity to correct or<br />
enhance patient outcomes. We continuously review<br />
the outcomes of patients at SJMH, and the following<br />
presents our patient care evaluation for those<br />
individuals with lung cancer including both<br />
non-small cell and small cell lung cancers.<br />
An estimated 222,520 new cases of lung cancer are<br />
expected in the United States for 2010, accounting<br />
for about 15% of cancer diagnoses. The incidence<br />
rate is declining significantly in men, from a high of<br />
102.1 cases per 100,000 in 1984 to 71.3 cases in 2006.<br />
In women, the rate is approaching a plateau after a<br />
long period of increase. Lung cancer is classified<br />
clinically as small cell (14%) or non-small cell (85%)<br />
for purposes of treatment.<br />
According to the National Cancer Institute, lung cancer<br />
is the leading cause of cancer-related mortality in the<br />
United States. An estimated 157,300 deaths, accounting<br />
for about 28% of all cancer deaths, are expected to<br />
occur in 2010. Since 1987, more women have died<br />
each year from lung cancer than from breast cancer.<br />
Since 1990, death rates among men have continued to<br />
decrease while female lung cancer death rates have<br />
been stable since 2003 after continuously increasing for<br />
several decades.<br />
Cigarette smoking is by far the most important risk<br />
factor for lung cancer. Cigar and pipe smoking also<br />
increase risk. Other risk factors include occupational<br />
or environmental exposure to secondhand smoke,<br />
radon, asbestos, certain metals, some organic<br />
chemicals, radiation, air pollution, and a history<br />
of tuberculosis. Genetic susceptibility plays a<br />
contributing role in the development of lung<br />
cancer, especially in those who develop the<br />
disease at a younger age.<br />
2010 Annual Cancer Report • 25
QUALITY INITIATIVES AND OUTCOMES (con’t)<br />
American College of Surgeons’ Commission on Cancer:<br />
Outcomes Comparison (con’t)<br />
A total of 252 new analytic lung cancer cases (267 including non-analytic)<br />
were diagnosed at SJMH in 2009, accounting for 11.5% of all new cancer cases.<br />
Incidence was divided equally between the sexes, with males accounting for<br />
136 and females totaling 131.<br />
Survival Statistics<br />
TABLE 1: Distribution by Age at Diagnosis<br />
Lung Cancer (Analytic Cases)<br />
Age at Diagnosis % & # New Diagnoses # New Diagnoses<br />
SJMH<br />
National Cancer Data<br />
Base (Ncdb)*<br />
0 - 29 0.4% (1) 0.2%<br />
30 - 39 0% (0) 0.8%<br />
40 - 49 3.2% (8) 4.5%<br />
50 - 59 19.1% (48) 18.1%<br />
60 - 69 27.4% (69) 29.4%<br />
70 - 79 33.3% (84) 34.8%<br />
80 - 89 15.9% (40) 11.5%<br />
90+ 0.8% (2) 0.8%<br />
*Clearly demonstrates that the age of patients diagnosed with lung cancer at SJMH is<br />
consistent with national norms.<br />
TABLE 2: Distribution by Stage<br />
Lung Cancer (Analytic Cases)<br />
Stage at Diagnosis SJMH (2009) National Cancer Data<br />
Base (Ncdb)*<br />
Stage I 24.6% (62) 5.4%<br />
Stage II 3.6% (9) 3.3%<br />
Stage III 21.0% (53) 25.5%<br />
Stage IV 38.5% (97) 52.6%<br />
Unknown/Unstaged 12.3% (31) 12.8%<br />
It is of interest to note that almost 25% of SJMH patients are diagnosed with Stage I<br />
local disease as compared with 5.4% of patients nationally. The reasons for this are<br />
not obvious; however, the NCDB data is from earlier years (2000-2007) which might<br />
contribute to the difference as improvements in diagnostic technology have been<br />
made over the years.<br />
*Please note that NCDB Data is from years 2000-2007, which is the most current national<br />
information available.<br />
26 • 2010 Annual Cancer Report
TABLE 3: Initial Therapy<br />
Lung Cancer<br />
Treatment of Modality SJMH (%) National Cancer Data<br />
Base (Ncdb)*<br />
Surgery Only 14.3% (36) 25.6%<br />
Chemotherapy Only 13.1% (33) 7.0%<br />
Radiation Therapy Only 13.9% (35) 10.6%<br />
Radiation + Chemotherapy 17.8% (45) 17.5%<br />
Palliative Treatment* 19.8% (50) Not Specified<br />
Other/Unknown 16.7% (41) 19.4%<br />
Diagnosis Only 13.1% (33) 16.3%<br />
*Palliative treatment incorporates any care provided in an effort to alleviate symptoms. It may<br />
include surgery, radiation, therapy, chemotherapy, and/or other pain management therapy.<br />
Data from the SJMH Tumor Registry compares SJMH lung cancer five-year<br />
survival with the National Cancer Database.<br />
Relative Survival<br />
by Summary at Diagnosis<br />
Stage at Diagnosis<br />
% Five Year Survival % Five Year Survival<br />
SJMH<br />
National Cancer Data<br />
Base (Ncdb)<br />
I 44.9% 46.5%<br />
II 28.0% 26.9%<br />
III 12.8% 11.2%<br />
IV 2.3% 2.4%<br />
Five-year survival information includes patients diagnosed in years 1998 – 2002.<br />
Note that the SJMH data clearly mimics national survival rates.<br />
2010 Annual Cancer Report • 27
APPENDICES<br />
2009 Primary Site: Body <strong>System</strong>, Sex, Class, Status and Best AJCC Stage<br />
Primary Site<br />
ORAL CAVITY & PHARYNX<br />
Sex<br />
Class of Case<br />
Status<br />
Stage Distribution - Analytic Cases Only<br />
Total (%) M F Analy NA Alive Exp Stg 0 Stg I Stg II Stg III Stg IV 88 Unk Blank/Inv<br />
34 (1.4%) 22 12 32 2 29 5 1 5 6 4 11 0 4 1<br />
1 (0.0%) 0 1 0 1 0 1 0 0 0 0 0 0<br />
9 (0.4%) 7 2 8 1 0 0 1 2 5 0 1 0<br />
9 (0.4%) 5 4 9 0 0 2 2 1 1 0 1 0<br />
5 (0.2%) 2 3 3 2 1 2 2 0 0 0 0 0<br />
1 (0.0%) 1 0 1 0 0 0 0 0 1 0 0 0<br />
6 (0.2%) 5 1 6 0 0 0 1 1 3 0 1 0<br />
1 (0.0%) 1 0 1 0 0 0 0 0 1 0 0 0<br />
1 (0.0%) 1 0 0 1 0 0 0 0 0 0 1 0<br />
1 (0.0%) 0 1 1 0 0 0 0 0 0 0 0 1<br />
Lip 1 0<br />
Tongue 9 0<br />
Salivary Glands 7 2<br />
Gum & Other Mouth 5 0<br />
Nasopharynx 1 0<br />
Tonsil 6 0<br />
Oropharynx 1 0<br />
Hypopharynx 1 0<br />
Other Oral Cavity & Pharynx 1 0<br />
DIGESTIVE SYSTEM<br />
349 (14.2%)<br />
187 162 329 20 273 76 3 68 49 68 60 11 70 0<br />
Esophagus 29 (1.2%) 26 3 28 1 22 7 0 5 2 5 7 1 8 0<br />
Stomach 16 (0.7%) 9 7 15 1 9 7 0 5 0 2 3 1 4 0<br />
Small Intestine 10 (0.4%) 6 4 10 0 9 1 0 2 0 1 0 4 3 0<br />
Colon Excluding Rectum 142 (5.8%) 79 63 133 9 130 12 0 33 20 40 20 2 18 0<br />
Cecum<br />
23 11 12 21 2 21 2 0 7 2 6 2 1 3 0<br />
Appendix<br />
6 5 1 4 2 5 1 0 0 0 0 2 0 2 0<br />
Ascending Colon<br />
44 27 17 44 0 42 2 0 10 9 18 4 0 3 0<br />
Hepatic Flexure<br />
5 4 1 4 1 3 2 0 1 0 1 2 0 0 0<br />
Transverse Colon<br />
13 6 7 13 0 12 1 0 2 3 1 3 0 4 0<br />
Splenic Flexure<br />
3 3 0 3 0 3 0 0 3 0 0 0 0 0 0<br />
Descending Colon<br />
7 3 4 7 0 5 2 0 0 1 5 0 0 1 0<br />
Sigmoid Colon<br />
35 17 18 34 1 35 0 0 10 5 9 5 1 4 0<br />
Large Intestine, NOS<br />
6 3 3 3 3 4 2 0 0 0 0 2 0 1 0<br />
Rectum & Rectosigmoid 68 (2.8%) 35 33 63 5 64 4 1 16 10 12 10 3 11 0<br />
Rectosigmoid Junction<br />
7 2 5 7 0 7 0 0 0 3 1 1 0 2 0<br />
Rectum<br />
61 33 28 56 5 57 4 1 16 7 11 9 3 9 0<br />
Anus, Anal Canal & Anorectum 4 (0.2%) 1 3 4 0 4 0 2 0 1 0 0 0 1 0<br />
Liver & Intrahepatic Bile Duct 8 (0.3%) 4 4 8 0 1 7 0 1 1 1 2 0 3 0<br />
Gallbladder 5 (0.2%) 1 4 5 0 2 3 0 0 2 1 0 0 2 0<br />
Other Biliary 9 (0.4%) 4 5 9 0 6 3 0 1 1 0 1 0 6 0<br />
Pancreas 54 (2.2%) 21 33 52 2 23 31 0 4 12 5 17 0 14 0<br />
Retroperitoneum 4 (0.2%) 1 3 2 2 3 1 0 1 0 1 0 0 0 0<br />
RESPIRATORY SYSTEM<br />
283 (11.5%) 151 132 268 15 205 78 3 67 12 56 99 2 29 0<br />
Larynx 16 (0.7%) 15 1 16 0 16 0 3 5 3 3 2 0 0 0<br />
Lung & Bronchus 267 (10.9%) 136 131 252 15 189 78 0 62 9 53 97 2 29 0<br />
BONES & JOINTS<br />
1 (0.0%) 0 1 1 0 1 0 0 1 0 0 0 0 0 0<br />
Bones & Joints 1 (0.0%) 0 1 1 0 1 0 0 1 0 0 0 0 0 0<br />
SOFT TISSUE<br />
6 (0.2%) Sex 5 1 Class 5 of Case 1 Status 5 1 0 0 Stage Distribution 1 - Analytic 1 Cases 1 Only 1 1 0<br />
Soft Primary Tissue Site(including Heart) 6 Total (0.2%) (%) M5 F1 Analy 5 NA 1 Alive 5 Exp 1 Stg 0 0 Stg 0 I Stg 1 II Stg 1 III Stg 1 IV 88 1 Unk 1 Blank/Inv 0<br />
SKIN EXCLUDING BASAL & SQ 216 (8.8%) 110 106 102 114 211 5 47 39 3 0 2 0 11 0<br />
Melanoma -- Skin 209 (8.5%) 108 101 98 111 204 5 47 37 2 0 2 0 10 0<br />
Other Non-Epithelial Skin 7 (0.3%) 2 5 4 3 7 0 0 2 1 0 0 0 1 0<br />
BASAL & SQUAMOUS SKIN<br />
3 (0.1%) 2 1 0 3 3 0 0 0 0 0 0 0 0 0<br />
Basal/Squamous cell carcinoma 3 (0.1%) 2 1 0 3 3 0 0 0 0 0 0 0 0 0<br />
BREAST<br />
523 (21.3%) 12 511 504 19 514 9 118 222 86 13 9 0 56 0<br />
Breast 523 (21.3%) 12 511 504 19 514 9 118 222 86 13 9 0 56 0<br />
FEMALE GENITAL SYSTEM<br />
175 (7.1%) 0 175 147 28 165 10 6 75 7 20 14 4 21 0<br />
Cervix Uteri 38 (1.5%) 0 38 15 23 38 0 0 8 1 2 2 0 2 – continued 0<br />
28 • 2010 Annual Cancer Report<br />
Corpus & Uterus, NOS 85 (3.5%) 0 85 83 2 82 3 0 57 3 8 3 3 9 0<br />
Corpus Uteri<br />
84 0 84 82 2 81 3 0 57 3 8 3 2 9 0<br />
Uterus, NOS<br />
1 0 1 1 0 1 0 0 0 0 0 0 1 0 0
SKIN EXCLUDING BASAL & SQ 216 (8.8%) 110 106 102 114 211 5 47 39 3 0 2 0 11 0<br />
Melanoma -- Skin 209 (8.5%) 108 101 98 111 204 5 47 37 2 0 2 0 10 0<br />
Other Non-Epithelial Skin 7 (0.3%) 2 5 4 3 7 0 0 2 1 0 0 0 1 0<br />
BASAL & SQUAMOUS SKIN<br />
3 (0.1%) 2 1 0 3 3 0 0 0 0 0 0 0 0 0<br />
Basal/Squamous cell carcinoma 3 (0.1%) 2 1 0 3 3 0 0 0 0 0 0 0 0 0<br />
BREAST<br />
523 (21.3%) 12 511 504 19 514 9 118 222 86 13 9 0 56 0<br />
Breast 523 (21.3%) 12 511 504 19 514 9 118 222 86 13 9 0 56 0<br />
ORAL FEMALE CAVITY GENITAL & PHARYNX SYSTEM<br />
34 175 (1.4%) (7.1%) 22 0 12 175 32 147 228<br />
29 165 510<br />
16 575 67 420 11 14 04 421 10<br />
Lip Cervix Uteri 138 (0.0%) (1.5%)<br />
0 138 115 023<br />
038 10<br />
0 18 01 02 02 0 02 0<br />
Tongue Corpus & Uterus, NOS 985 (0.4%) (3.5%) 70 285 983 02<br />
882 13<br />
0 057 13 28 53 03 19 0<br />
Salivary Corpus Glands Uteri<br />
984 (0.4%) 50 484 782 2 981 03<br />
0 257 23 18 13 02 19 0<br />
Gum Uterus, & Other NOSMouth 51 (0.2%) 20 31 51 0 31 20<br />
10 20 20 0 0 01 0 0<br />
Nasopharynx Ovary 137 (0.0%) (1.5%) 10 037 136 01<br />
132 05<br />
0 09 01 09 19 0 08 0<br />
Tonsil Vagina 61 (0.2%) (0.0%) 50 1 61 0 61 0 01 0 10 10 30 0 10 0<br />
Oropharynx Vulva 112 (0.0%) (0.5%) 10 012 110 02<br />
111 01<br />
05 01 02 0 10 0 02 0<br />
Hypopharynx Other Female Genital Organs 12 (0.0%) (0.1%) 10 02 12 0 01 1<br />
0 0 0 01 0 01 10 0<br />
Other MALE Oral GENITAL Cavity SYSTEM & Pharynx 1326 (0.0%) (13.3%) 0326 10 1316 010<br />
1322 04<br />
0 08 0217 027 09 0 054 1<br />
DIGESTIVE Prostate SYSTEM<br />
349 317 (14.2%) (12.9%) 187 317 162 0 329 307 20 10 273 313 76 4 30 68 1 49 215 68 27 60 9 11 0 70 54 01<br />
Esophagus Testis 29 8 (0.3%) (1.2%) 26 8 30 28 8 10<br />
22 8 70<br />
0 57 21 50 70 10 80 0<br />
Stomach Other Male Genital Organs 16 1 (0.0%) (0.7%) 91 70 15 1 10<br />
91 70<br />
0 50 01 20 30 10 40 0<br />
Small URINARY Intestine SYSTEM<br />
10 187 (0.4%) (7.6%) 6133 454 10 174 013<br />
9178 19<br />
079 247 010 16 08 41 323 0<br />
Colon Urinary Excluding Bladder Rectum 142 125 (5.8%) (5.1%) 79 89 63 36 133 116 9 130 119 12 6 075 33 17 20 10 40 0 20 5 20 18 9 0<br />
Kidney Cecum& Renal Pelvis 58 23 (2.4%) 11 41 12 17 21 55 23<br />
21 55 23<br />
03 729 20 6 23 1 313 0<br />
Ureter Appendix<br />
36 (0.1%) 52 1 43 20<br />
53 10<br />
01 01 0 0 20 0 21 0<br />
Other Ascending Urinary Colon Organs 144 (0.0%) 27 1 17 0 44 0 01<br />
42 1 20<br />
0 10 0 90 18 0 40 0 30 0<br />
EYE Hepatic & ORBIT Flexure<br />
25 (0.1%) 41 1 40 12<br />
32 20<br />
0 10 0 10 20 0 0 0<br />
Transverse Colon<br />
Eye & Orbit 2<br />
13<br />
(0.1%)<br />
6 7 13 0 12 1<br />
2 3 1 3 4 1 1 0 2 2 0 0 0 0 0 0 0 0 0<br />
Splenic Flexure<br />
3 3 0 3 0 3 0<br />
3 0 BRAIN & OTHER NERVOUS SY 81 (3.3%) 29 52 77 4 72 9 0 0 0 0 0 77 0 0<br />
Descending Colon<br />
7 3 4 7 0 5 2<br />
1 5 0 1 Brain 33 (1.3%) 19 14 31 2 26 7 0 0 0 0 0 31 0 0<br />
Sigmoid Colon<br />
35 17 18 34 1 35 0<br />
10 5 9 5 1 4 Cranial Nerves Other Nervous S 48 (2.0%)<br />
Large Intestine, NOS<br />
10 38 46 2 46 2 0 0 0 0 0 46 0 0<br />
6 3 3 3 3 4 2 0 1 Rectum ENDOCRINE & Rectosigmoid SYSTEM<br />
68 65 (2.8%) (2.6%)<br />
35 18 33 47 63 61 54<br />
64 60 45<br />
10 16 24 10 5 12 8 10 5 314 11 5 0<br />
Thyroid Rectosigmoid Junction<br />
48<br />
7<br />
(2.0%)<br />
211 537 747 01<br />
744 04<br />
0 024 35 18 15 0 25 0<br />
Other Rectum Endocrine including Thymu 17 61 (0.7%) 33 7 28 10 56 14 53<br />
57 16 41<br />
10 16 0 70 11 0 90 314 90 0<br />
Anus, LYMPHOMA Anal Canal & Anorectum 4101 (0.2%) (4.1%) 159 342 488 013<br />
494 07<br />
20 031 114 010 028 03 12 0<br />
Liver Hodgkin & Intrahepatic Lymphoma Bile Duct 810 (0.3%) (0.4%) 47 43 810 0 110 70<br />
0 14 14 12 20 0 30 0<br />
Gallbladder Hodgkin - Nodal<br />
59 (0.2%) 16 43 59 0 29 30<br />
0 03 24 12 0 0 20 0<br />
Other Hodgkin Biliary - Extranodal<br />
91 (0.4%) 41 50 91 0 61 30<br />
0 1 10 0 10 0 60 0<br />
Pancreas Non-Hodgkin Lymphoma 54 91 (2.2%) (3.7%)<br />
21 52 33 39 52 78 213<br />
23 84 31 7<br />
0 427 12 10 58 17 28 03 14 2 0<br />
Retroperitoneum NHL - Nodal<br />
436 (0.2%) 121 315 233 23<br />
332 14<br />
0 18 04 17 013 01 0 0<br />
NHL - Extranodal<br />
RESPIRATORY SYSTEM<br />
283<br />
55<br />
(11.5%)<br />
31 24 45 10 52 3 0 19 6 1 15 2 2 0<br />
151 132 268 15 205 78 3 67 12 56 99 29 MYELOMA<br />
28 (1.1%) 17 11 27 1 25 3 0 0 0 0 0 27 0 0<br />
Larynx 16 (0.7%) 15 1 16 0 16 0 3 5 3 3 2 0 Myeloma 28 (1.1%) 17 11 27 1 25 3 0 0 0 0 0 27 0 0<br />
Lung & Bronchus 267 (10.9%) 136 131 252 15 189 78<br />
62 9 53 97 2 29 LEUKEMIA<br />
33 (1.3%) 14 19 29 4 26 7 0 0 0 0 0 29 0 0<br />
BONES & JOINTS<br />
1 (0.0%) 0 1 1 0 1 0<br />
1 0 Lymphocytic Leukemia 8 (0.3%) 2 6 5 3 8 0 0 0 0 0 0 5 0 0<br />
Bones & Joints 1 (0.0%) 0 1 1 0 1 1 0 Acute Lymphocytic Leukemia 1 0 1 1 0 1 0 0 0 0 0 0 1 0 0<br />
SOFT TISSUE<br />
6 (0.2%) 5 5 1 5 1<br />
1 1 1 1 Chronic Lymphocytic Leukemia 7 2 5 4 3 7 0 0 0 0 0 0 4 0 0<br />
Soft Tissue (including Heart) 6 (0.2%)<br />
Myeloid & Monocytic Leukemia 23 (0.9%)<br />
5 1 5 1 5 1<br />
1 1 1 1 1 11 12 23 0 16 7 0 0 0 0 0 23 0 0<br />
Acute Myeloid Leukemia<br />
15 7 8 15 0 8 7 0 0 0 0 0 15 0 0<br />
Chronic Myeloid Leukemia<br />
7 3 4 7 0 7 0 0 0 0 0 0 7 0 0<br />
Other Myeloid/Monocytic Leuke 1 1 0 1 0 1 0 0 0 0 0 0 1 0 0<br />
Other Leukemia 2 (0.1%) 1 1 1 1 2 0 0 0 0 0 0 1 0 0<br />
MESOTHELIOMA<br />
4 (0.2%) 3 1 3 1 4 0 0 2 0 1 0 0 0 0<br />
Mesothelioma 4 (0.2%) 3 1 3 1 4 0 0 2 0 1 0 0 0 0<br />
MISCELLANEOUS<br />
39 (1.6%) 19 20 38 1 27 12 0 0 0 0 0 38 0 0<br />
Miscellaneous 39 (1.6%) 19 20 38 1 27 12 0 0 0 0 0 38 0 0<br />
Primary Site<br />
Primary Site<br />
Sex Class of Case Status<br />
Stage Distribution - Analytic Cases Only<br />
Total (%) M F Analy NA<br />
Alive Exp Stg 0 Stg I Stg II Stg III Stg IV 88 Unk Blank/Inv<br />
Sex Class of Case Status<br />
Stage Distribution - Analytic Cases Only<br />
Total (%) M F Analy NA<br />
Alive Exp Stg 0 Stg I Stg II Stg III Stg IV 88 Unk Blank/Inv<br />
Total 2,456 1,108 1,348 2,201 255 2,216 240 257 589 410 214 246 207 276 2<br />
Exclusions: Not Male and Not Female 0<br />
2010 Annual Cancer Report • 29
2009 BEST<br />
GENERAL SUMMARY STAGES<br />
Breast<br />
Analytic Breast Cases<br />
Total Number of Patients<br />
PROSTATE<br />
Analytic Prostate Cases<br />
Total Number of Patients<br />
250<br />
200<br />
150<br />
100<br />
50<br />
0<br />
In-situ Local Regional Distant Unknown<br />
250<br />
200<br />
150<br />
100<br />
The four most commonly occurring<br />
malignancies both nationally and<br />
St. <strong>Joseph</strong> <strong>Mercy</strong> Cancer Center<br />
are breast, prostate, lung and colon.<br />
BREAST CANCER<br />
We have seen a 20 percent increase<br />
in the number of new breast cancer<br />
cases. The distribution of the stage<br />
of disease at diagnosis virtually<br />
replicates that of the past few years<br />
with approximately 67 percent of<br />
our analytic case diagnosed with<br />
in situ or local disease.<br />
50<br />
0<br />
LUNG<br />
50<br />
45<br />
40<br />
Local Regional Distant Unknown<br />
Analytic Lung Cases<br />
Male<br />
Female<br />
PROSTATE CANCER<br />
There was a slight decrease in the<br />
number of our prostate cancer cases<br />
over the past year. Of the 305 analytic<br />
cases, 70% were diagnosed with<br />
local disease.<br />
Total Number of Patients<br />
COLON<br />
Total Number of Patients<br />
35<br />
30<br />
25<br />
20<br />
15<br />
10<br />
5<br />
0<br />
35<br />
30<br />
25<br />
20<br />
15<br />
10<br />
Local Regional Distant Unknown<br />
Analytic Colon Cases<br />
Male<br />
Female<br />
LUNG CANCER<br />
New lung cancer cases remained<br />
virtually the same as last year<br />
(2009 = 251 cases versus 2008 = 264).<br />
This number has remained fairly<br />
consistent over the years.<br />
COLON CANCER<br />
There was a 13% increase in the<br />
number of new colon cancer cases<br />
in 2009, attributable to outreach and<br />
screening activities.<br />
5<br />
0<br />
Local Regional Distant Unknown<br />
30 • 2010 Annual Cancer Report
2009 TUMOR BOARDS / REGISTRY<br />
Tumor Boards<br />
Total Meetings<br />
Central Tumor Board 43<br />
(all cancer types)<br />
Breast Cancer 22<br />
Genitourinary Cancers 8<br />
Head and Neck 20<br />
Tumor Registry<br />
Statistics<br />
Total Records in Database 31,322<br />
Living Patients 15,147<br />
Cases Abstracted 2,454<br />
Data Requests From:<br />
• Physicians 3<br />
• Administration or Research 3<br />
• Other Hospitals/Tumor Registries 75<br />
2010 Annual Cancer Report • 31
APPENDICES<br />
2009-2010 Highlights of Scholarly Activities<br />
Beekman KW, Hussain M. Hormonal<br />
Approaches in Prostate Cancer: Application in<br />
the Contemporary Prostate Cancer Patient.<br />
Urol Oncol. 2008 Jul-Aug;26(4):415-9. Review.<br />
Hines SL, Mincey BA, Sloan JA, Thomas SP,<br />
Chottiner E, Loprinzi CL, Carlson MD, Atherton<br />
PJ, Salim M, Perez EA. Phase III Randomized,<br />
Placebo-Controlled, Double-Blind Trial of<br />
Riedronate for the Prevention of Bone Loss<br />
in Premenopausal Women Undergoing<br />
Chemotherapy for Primary Breast Cancer.<br />
J Clin Oncol. 2009 Mar 1;27(7):1047-53.<br />
Epub 2008 Dec 15.<br />
Byker G, Dinh MT, Gunaratnam NT, Robinson<br />
EA, Shehab TM, Malani, AN. Management<br />
of Clostridium Difficile Infection: Survey of<br />
Practices and Compliance with national<br />
Guidelines among Primary Care Physicians.<br />
Infect Control and Hosp Epidemiol. 2009<br />
Apr;(4):397-9.<br />
Grewal JS, Brar PK, Sahijdak WM, Tworek JA,<br />
Chottiner EG. Bing-Neel syndrome: a case report<br />
and systematic Review of Clinical Manifestations,<br />
diagnosis and treatment Options. Clin<br />
Lymphoma Myeloma. 2009 Dec;9(6):462-6.<br />
Grewal JS, Smith LB, Winegarden JD 3 rd , Krauss<br />
JC, Tworek JA, Schnitzer B. Highly Aggressive<br />
ALK-positive Anaplastic Large Cell Lymphoma<br />
with a Leukemic Phase and Multi-organ Involvement:<br />
A Report of Three Cases and a Review of<br />
the Literature. Ann Hematol. 2007 Jul;86(7)499-<br />
508. Epub 2007 Mar 30. Review.<br />
Jatoi A, Schild SE, Foster N, Henning GT,<br />
Dornfeld KJ, Flynn PJ, Fitch TR, Dakhil SR,<br />
Rowland KM, Stella PJ, Soori GS, Adjei AA. A<br />
Phase II Study of Cetuximab and Radiation in<br />
Elderly and/or Poor Performance Status<br />
Patients with Locally Advanced Non-Small<br />
Lung Cancer (N0422). Ann Oncol. 2010 Jun 21.<br />
Loprinzi CL, Dueck AC, Khoyratty BS, Barton DL,<br />
Jafar S, Rowland KM Jr, Atherton PJ, Marsa GW,<br />
Knutson WH, Bearden JD 3rd, Kottschade L,<br />
Fitch TR. A Phase III Randomized, double-blind,<br />
placebo-controlled trial of gabapentin in the<br />
management of hot flashes in men (N00CB).<br />
Ann Oncol. 2009 Mar;20(3):542-9. Epub Jan 6.<br />
Greil S, Robinson EA, Singal B, Kleer E. Efficacy<br />
over time of LHRH Analogs in the Treatment<br />
of Pca—a Prospective Analysis Using Serum<br />
Testosterone to Determine Doing Intervals.<br />
Urology. 2009 Mar;73(3):631-4. Epub 2008<br />
Dec 24.<br />
Hayes MJ, Carey JL, Krauss JC, Hedstrom DL,<br />
Gulbranson RL, Keren DF. Low IgE Monoclonal<br />
Gammopathy Level in Serum Highlights 20-yr<br />
Survival in a Case of IgE Multiple Myeloma.<br />
Eur J Haematol. 2007 Apr;78(4):353-7.<br />
Pulaski HL, Spahlinger G, Silva IA, McLean K,<br />
Kueck AS, Reynolds RK, Coukos G. Conejo-<br />
Garcia JR, Buckanovich RJ. Identifying<br />
Alemtuzumab as an Anti-Myeloid Cell<br />
Antiangiogenic Therapy for the Treatment of<br />
Ovarian Cancer. J Transl Med. 2009 Jun<br />
19;7:49.<br />
Kueck A, Opipari AW Jr, Griffith KA, Tan L,<br />
Choi M, Huang J, Wahl H, Liu JR. Resveratrol<br />
Inhibits Glucose Metabolism in Human<br />
Ovarian Cancer Cells. Gynecol Oncol. 2007<br />
Dec;107(3):450-7. Epub 2007 Sep 10.<br />
Uhm JH, Ballman KV, WU W, Giannini C, Krauss<br />
JC, Buckner, JC, James CD, Scheithauer BW,<br />
Behrens RJ, Flynn PJ, Schaefer PL, Dakhill SR,<br />
Jaeckle KA. Phase II Evaluation of Gefitinib<br />
in Patients with Newly Diagnosed Grade 4<br />
Astrocytoma: Mayo/ North Central Cancer<br />
Treatment Group Study N0074. Int J Radiat<br />
Oncol Biol Phys. 2010 May 24.<br />
32 • 2010 Annual Cancer Report
Barton DL, LaVasseur BI, Sloan JA, Stawis AN,<br />
Flynn KA, Dyar M, Johnson DB, Atherton PJ,<br />
Diekmann B, Loprinzi CL. Phase III, Placebo-<br />
Controlled Trial of Three Doses of Citalopram<br />
for the Treatment of Hot Flashes: NCCTG Trial<br />
N05C9. J Clin Oncol. 2010 Jul 10;28(20):3278-83.<br />
Epub 2010 May 24<br />
Smith DC, Mackler NJ, Dunn RL, Hussain M,<br />
Wood D, Lee CT, Sanda M, Vaishampayan U,<br />
Petrylak DP, Quinn DI, Beekman K, Montie JE.<br />
Phase II Trial of Paclitaxel, Carboplatin and<br />
Gemcitabine in Patients with Locally<br />
Advanced Carcinoma of the Bladder.<br />
J Urol. 2008 Dec;180(6):2384-8; discussion 2388.<br />
Epub 2008 Oct 18.<br />
Chen AM, Lee NY, Yang CC, Liu T, Narayan S,<br />
Vijayakumar S, Purdy JA. Comparison of<br />
Intensity-Modulated Radiotherapy Using<br />
Helical Tomotherapy and Segmental Multileaf<br />
Collimator-based Techniques for<br />
Nasopharyngeal Carcinoma: Dosimetric<br />
Analysis Incorporating Quality Assurance<br />
Guidelines from RTOG 0225. Technol Cancer<br />
Res Treat. 2010 Jun;9(3):291-8.<br />
Moraska AR, Atherton PJ, Szydlo DW, Barton DL,<br />
Stella PJ, Rowland KM Jr, Schaefer PL, Krook J,<br />
Bearden JD, Loprinzi CL. Gabapentin for the<br />
Management of Hot Flashes in Prostate Cancer<br />
Survivors: A Longitudinal Continuation Study-<br />
NCCTG Trial N00CB. J Support Oncol. 2010<br />
May-Jun;8(3):128-32.<br />
Haura EB, Ricart AD, Larson TG, Stella PJ,<br />
Bazhenova L, Miller VA, Cohen RB, Eisenberg<br />
PD, Selaru P, Wilner KD, Gadgeel SM. A Phase II<br />
Study of PD-0325901, An Oral MEK Inhibitor, In<br />
Previously Treated Patients with Advanced<br />
Non-Small Cell Lung Cancer. Clin Cancer Res.<br />
2010 Apr 15;16(8):2450-7. Epub 2010 Mar 23.<br />
Jatoi A, Foster NR, Egner JR, Burch PA, Stella, PJ,<br />
Rubin J, Dakhil SR, Sargent DJ, Murphy BR,<br />
Alberts SR. Older Versus Younger Patients with<br />
Metastatic Adenocarcinoma of the Esophagus,<br />
Gastroesophageal Junction, and Stomach:<br />
A Pooled Analysis of Eight consecutive North<br />
Central Treatment Group (NCCTG) Trials.<br />
Int J Oncol. 2010 Mar;36(3):601-6.<br />
Adjei AA, Mandrekar SJ, Dy GK, Molina JR,<br />
Gandara DR, Allen Ziegler KL, Stella PJ,<br />
Rowland KM Jr, Schild SE, Zinner RG. Phase II<br />
Trial of Pemetrexed Plus Bevacizumab for<br />
Second-Line Therapy of Patients with Advanced<br />
Non-Small-Cell Lung Cancer: NCCTG and<br />
SWOG Study N0426. J Clin Oncol. 2010 Feb<br />
1;28(4):614-9. Epub 2009 Oct. 19.<br />
Tan WW, Hillman DW, Salim M, Northfelt DW,<br />
Anderson DM, Stella PJ, Niedringhaus R,<br />
Bernath AM, Gamini SS, Palmieri F, Perez EA.<br />
N0332 Phase II Trial of Weekly Irinotecan<br />
Hydrochloride and Docetaxel in Refractory<br />
Metastatic Breast Cancer: A North Central<br />
Cancer Treatment Group (NCCTG) Trial. Ann<br />
Oncol. 2010 Mar;21(3):493-7. Epub 2009 Jul 22 .<br />
Socinski MA, Saleh MN, Trent DF, Dobbs TW,<br />
Zehngebot LM, Levine MA, Bordoni R, Stella PJ.<br />
A Randomized Phase II Trial of Two Dose<br />
Schedules of Carboplatin/Paclitaxel/<br />
Cetuximab in Stage IIIB/IV Non-Small-Cell Lung<br />
Cancer (NSCLC). Ann Oncol. 2009 Jun;20(6):1068-<br />
73. Epub 2009 Feb 2.<br />
Wasco MJ, Daignault S, Bradley D, Shah RB.<br />
Nested variant of urothelial carcinoma: a<br />
clinicopathologic and immunohistochemical<br />
study of 30 pure and mixed cases. Hum Pathol.<br />
2010 Feb;41(2):163-71. Epub 2009 Oct 1.<br />
Weizer AZ, Wasco MJ, Wang R, Daignault S,<br />
Lee CT, Shah RB. Multiple adverse histological<br />
features increase the odds of under staging T1<br />
bladder cancer. J Urol. 2009 Jul;182(1):59-65;<br />
discussion 65. Epub 2009 May 17. Erratum in:<br />
J Urol. 2009 Sep;182(3):1237.<br />
2010 Annual Cancer Report • 33
APPENDICES<br />
2009-2010 Publications & Resident Awards SJMHS Dermatology<br />
JAAD Publications<br />
° Jason Mazzurco: Phaeohyphomycosis Caused by<br />
Phaeoacremonium Species in a Patient Taking<br />
Infliximab (Accepted for publication 4/2010)<br />
° Amy Basile: Disseminated Strongyloides stercoralis:<br />
Hyperinfection during medical immunosuppression.<br />
(Accepted for publication 2/22/2010)<br />
International Journal of Dermatology<br />
Publications<br />
° Jason Mazzurco: Localized Mycosis Fungoides of the<br />
Bilateral Thumbs and Nail Units Treated with Orthovoltage<br />
Radiation Accepted for publication (3/10)<br />
° Jason Mazzurco: Eruptive Disseminated Spitz Nevi in<br />
a 26-Year-Old African American Woman (6/10)<br />
AOCD Publications<br />
° Amy Basile: Plexiform Firohistiocytoma in a 13-yearold<br />
female: Case report and brief review. April 2010,<br />
Volume 16, Number 1.<br />
Journal of Drugs in Dermatology Publications<br />
° Brooke Bair: Lenalidomide manuscript (6/10)<br />
Other Publications<br />
° Jeni Stead: Palmoplantar erythrodysesthesia<br />
syndrome induced by capecitabine (Xeloda(r)) -<br />
Dermatology Clinics (6/10)<br />
Michigan Dermatology Society<br />
° 5 Honorable mentions: D. Cleaver, J. Mazzurco, J.<br />
Stead, A. Basile, C. Messana<br />
° Winter MDS Meeting: Residency program hosted the<br />
meeting at SJMHS in February 2010 comprised of 36<br />
patient presentations of interesting & difficult<br />
dermatological cases.<br />
•Resident PowerPoint Presentations:<br />
6/10 residents presented interesting cases<br />
Resident PowerPoint Presentations<br />
° AOCD New Orleans, Nov. 2009: 7/10 residents<br />
presented 15-minute PowerPoint presentations<br />
° Cosmetic Surgery Forum, Las Vegas Dec. 2009:<br />
David Cleaver Presented a surgical case<br />
° AAD Miami FL, March 2010: 5 Residents presented<br />
at Gross & Microscopic Symposium<br />
• Brooke Bair, Nichole Edwards, Emily Fibeger,<br />
Jennifer Stead, Christopher Messana<br />
° Dominican Republic: Interesting cases from Michigan<br />
Presented by J.Mazzurco, D.Cleaver, B.Bair<br />
° AOCD midyear meeting, Sedona, Az, April 2010:<br />
Two residents presented<br />
Resident Awards<br />
° Jason Mazzurco: Australia Surgical Paper Competition<br />
Winner, Nov. 2009<br />
° David Cleaver: ASDS Surgical Scholarship Recipient<br />
Dec. 2009<br />
° Brooke Bair: Caribbean Dermatology Recipient<br />
Jan. 2010 - Triax Resident Research Award<br />
° ARTE Scholarship to attend Orlando Dermatology<br />
meeting, Jan. 2010: Jason, David, Brooke<br />
° Brooke Bair: ASLM Resident Research competition<br />
for oral presentation<br />
° Brooke Bair: 2008-2009 Michigan Dermatological<br />
Society Residents’ Research Paper Award<br />
Ongoing Research<br />
° Cutera laser research: Four active abstracts in<br />
development (1st/2nd year residents)<br />
° Teledermatology Study<br />
Resident Poster Presentations<br />
° ASDS Meeting Phoenix, Az, Sept. 2009: David Cleaver<br />
presented surgical poster<br />
° ASDP Meeting Chicago, IL, Oct. 2009: 3 Residents<br />
presented pathology posters<br />
• Brooke Bair, Sarah Maggio, Jennifer Stead<br />
° MDS Winter Meeting, SJMHS February 2010:<br />
5 Residents presented posters<br />
° SJMHS Resident research poster session, April, 2010:<br />
9/10 Residents presented posters<br />
° ASDS Meeting Chicago 2010: Amy Basil presenting<br />
a poster on Mohs surgery for Merkel Cell CA<br />
34 • 2010 Annual Cancer Report
St. <strong>Joseph</strong> <strong>Mercy</strong><br />
Cancer Centers<br />
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Canton, MI 48188<br />
St. <strong>Joseph</strong> <strong>Mercy</strong> Cancer Program<br />
888-474-HOPE / 888-474-4673<br />
stjoeshealth.org