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ANNUAL REPORT - Saint Joseph Mercy Health System

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2010<br />

Annual Report<br />

Data Represented 2009


Table of Contents<br />

INTRODUCTION (2 - 3)<br />

2 Letter from the Medical Director<br />

3 Letter from Cancer Committee Chair<br />

EXECUTIVE SUMMARY (4 - 5)<br />

FOUNDATIONS OF CANCER CARE (6 -15)<br />

6 American College of Surgeons’ Commission on Cancer:<br />

Accreditation as a Teaching Hospital Cancer Program<br />

6 Cancer Program Overview<br />

7 Facilities<br />

8 Oncology Physician Specialists<br />

8 Medical Oncology<br />

9 Radiation Oncology<br />

10 Surgical Oncology<br />

10 Multidisciplinary Clinics<br />

11 Multidisciplinary Programs<br />

11 Breast Cancer Program<br />

12 Gastrointestinal Cancer Program<br />

(Colorectal, Hepatobiliary)<br />

13 Genitourinary Cancer Program<br />

(Renal, Prostate)<br />

13 Lung Cancer Program<br />

14 Gynecologic Oncology Program<br />

14 Neurologic Cancer Program<br />

(Brain, Spinal Cord)<br />

14 Head & Neck Cancer Program<br />

14 Endocrine Cancers (Thyroid)<br />

14 Skin Cancers (Melanoma)<br />

CANCER RESEARCH (16)<br />

16 MICHIGAN CANCER RESEARCH CONSORTIUM<br />

COMMUNITY CLINICAL ONCOLOGY PROGRAM<br />

(MCRC-CCOP)<br />

CARE ACROSS THE CONTINUUM (17)<br />

17 NATIONAL CANCER INSTITUTE COMMUNITY<br />

CANCER CENTERS PROGRAM GRANT (NCCCP)<br />

17 Program Overview<br />

17 Nurse Navigators<br />

18 Community Partnerships<br />

18 <strong>Health</strong> Disparities<br />

19 Biospecimen Research Initiatives<br />

19 Cancer Survivorship and Palliative Care Services<br />

PATIENT CENTEREDNESS (20)<br />

20 Oncology Patient Advocates Team<br />

20 Patient Satisfaction<br />

20 A Patient Speaks<br />

QUALITY INITIATIVES AND OUTCOMES (22 -27)<br />

22 Oncology & Infusion Collaborative Practice<br />

Team: Review of Chemotherapy Safety<br />

23 Chemotherapy Infusion Clinic: Streamlining<br />

<strong>System</strong>s - Chemotherapy Order Process<br />

23 Department of Radiation Oncology:<br />

Streamlining <strong>System</strong>s<br />

23 Cardiothoracic Surgeons: Benchmarking Utilizing<br />

the Society of Thoracic Surgeons Database<br />

24 Medical Oncologists: Quality Oncology<br />

Practice Initiative (QOPI)<br />

24 Medical Oncologists: Michigan Oncology<br />

Clinical Treatment Pathways Program<br />

24 Breast Program Quality Initiatives<br />

25 Cancer Research Audits (2009-2010)<br />

26 American College of Surgeons’ Commission<br />

on Cancer: Outcomes Comparison<br />

APPENDICES (28-34)<br />

28 Appendix A: Tumor Registry Analytical Cases<br />

(2009) by Diagnostic Site<br />

30 2009 Best General Summary Stages<br />

31 2009 Tumor Boards & Registry<br />

32 2009-2010: Highlights of Scholarly Activities<br />

34 2009-2010: Publications & Resident Awards<br />

SJMHS Dermatology<br />

2010 Annual Cancer Report • 1


Letter from the<br />

Medical Director<br />

Philip J. Stella, MD, Medical Director<br />

St. <strong>Joseph</strong> <strong>Mercy</strong> Cancer Program<br />

Principal Investigator, Michigan Cancer Research Consortium<br />

I am pleased to present the 2009-10 annual report of the St. <strong>Joseph</strong> <strong>Mercy</strong> Cancer Program. This<br />

past year truly has been eventful, highlighted by the awarding of a National Cancer Institute (NCI)<br />

Community Cancer Centers Program (NCCCP) contract. This prestigious award from the NCI signifies<br />

our program as one of a select group of community cancer programs in the country. It recognizes<br />

excellence in research and supports our efforts toward high-quality multidisciplinary care; in addition,<br />

it supports resources for a genetics counselor and nurse navigators, and provides resources for the<br />

underserved populations. The NCCCP contract also assists in the development of a tissue repository<br />

to help advance translational research.<br />

We are excited about the long-awaited expansion of our multidisciplinary clinics this coming fall. In<br />

addition to a lung cancer clinic, we will now be able to see patients with breast, gastrointestinal (GI),<br />

prostate, head and neck cancer, and neuro-oncologic malignancies in a multidisciplinary fashion<br />

supported by nurse navigators to help facilitate timely access to state-of-the-art care for patients and<br />

providers.<br />

Speaking of access, we have expanded the oncology program with new satellites in Canton and Chelsea<br />

as well as the established sites in Brighton and Livonia. We look forward to adding a fellowship-trained<br />

breast surgeon to head a superb team of specialists and staff providing optimal breast care.<br />

I am particularly pleased with the work of our patient advocate committee. Under the leadership of Pastor<br />

Dave McNeil and Beth LaVasseur, RN, MSN, we have developed partnerships with American Cancer<br />

Society (ACS) and the Wellness Community to expand the services we provide to cancer patients.<br />

With patient representation on our program committees, we are fulfilling our mission to truly be patientcentered.<br />

Our work with Blue Cross Blue Shield of Michigan (BCBSM) to support quality initiatives such as Michigan<br />

Breast Oncology Quality Initiative (MiBOQI), Quality Oncology Practice Initiative (QOPI) and the Pathway<br />

Project is putting us on the cutting edge of measuring and implementing cost effective quality programs<br />

that are models of care garnering national recognition.<br />

Finally, we are promoting early detection and screening through an all-digital mammography network,<br />

a robust screening colonoscopy program and annual prostate and skin cancer screening events.<br />

In what promises to be a paradigm shifting approach, our Smoking Cessation Collaborative Practice<br />

Team has developed a program to train a champion in physician offices to identify and provide<br />

evidence-based intervention to our patients who are tobacco dependent.<br />

With 10 million dollars in grants and contracts over the next four or five years, a faculty committed to<br />

research and access to the latest technologic advancements such as robotic surgery and Cyberknife ® ,<br />

we are confident that we can provide the best cancer care for our patients.<br />

2 • 2010 Annual Cancer Report


Letter from the<br />

Cancer Committee Chair<br />

Timothy McHugh, MD, Chairperson<br />

St. <strong>Joseph</strong> <strong>Mercy</strong> Cancer Committee<br />

The Cancer Committee is a multidisciplinary committee charged with oversight of the quality of<br />

care delivered to patients as they traverse the health care system. As Chair of the SJMHS Cancer<br />

Committee, I am proud to report that we continue to exceed the standards for American College of<br />

Surgeons’ Commission on Cancer Hospital Teaching Programs. Accreditation by the American College<br />

of Surgeons’ Commission on Cancer is a very rigorous process that documents our compliance with<br />

multiple quality and process improvement initiatives set to define cancer programs of excellence.<br />

Through our accreditation by the American College of Surgeons our committee follows a comprehensive<br />

structure for the ongoing measurement of the quality of our program for all cancer related services.<br />

Only 25% of community cancer programs in the country are accredited. The standards measured<br />

represent care across the continuum: prevention, early-diagnosis, pre-treatment evaluation, staging,<br />

optimal treatment, rehabilitation, and surveillance for recurrent disease, support services and end of life<br />

care. We were particularly pleased this past year with the increasing amount of quality measurement<br />

data made available to the Committee and the increased focus on multidisciplinary care to improve the<br />

patient experience. A representative from the American Cancer Society has also joined our committee,<br />

which provides us with an excellent community partnership and expanded resources for our patients.<br />

At each Cancer Committee meeting we review the eight categories of ACOS standards, which provides<br />

us the opportunity to organize and manage the cancer program to assure multidisciplinary, integrated<br />

and comprehensive oncology services. Each of our twenty-five members is actively engaged in<br />

discussing and accepting the challenge to accomplish the newly identified goals the Committee sets<br />

for the program.<br />

Throughout this report you will see examples of the quality of care and process improvements that we<br />

review and oversee on a regular basis to assure the cancer program is not only meeting but exceeding<br />

the needs of our patients.<br />

2010 Annual Cancer Report • 3


EXECUTIVE SUMMARY<br />

The opening of the Robert H. and Judy Dow Alexander Cancer Care Center<br />

at St. <strong>Joseph</strong> <strong>Mercy</strong> Hospital in Ann Arbor in 1993 was the beginning of an<br />

extraordinary time in the evolution of cancer care in our community. In a<br />

short 16 years, SJMHS has developed an all-expansive oncology program<br />

that is recognized for its leadership and innovation in developing cancer<br />

services that continually look to the future for the newest technology,<br />

advanced treatment options, breakthrough medications, and programs<br />

that improve the cancer experience for individuals and families.<br />

The following highlights provide a historical context and illustrate the<br />

accomplishments and growth of the SJMHS cancer program.<br />

4 • 2010 Annual Cancer Report


° The Robert H. and Judy Dow Alexander Cancer<br />

Care Center on the SJMHS campus in Ann<br />

Arbor began as a new 30,000 square foot facility<br />

housing chemotherapy infusion services, medical<br />

oncology, laboratory services, and program<br />

offices. As the first dedicated cancer center in<br />

our service area, it became the model for care.<br />

Today, SJMHS cancer centers include additional<br />

state-of-the-art facilities in Brighton and Canton,<br />

with a fourth being planned for Chelsea. Services<br />

in all centers include both chemotherapy and<br />

radiation therapy as well as multidisciplinary clinic<br />

space and all ancillary services.<br />

° When the oncology program was being formalized<br />

in the early 1990’s, a total of four patients were<br />

enrolled in clinical trials through our affiliation with<br />

the Toledo Community Clinical Oncology Program.<br />

In 2009, SJMHS enrolled over 200 patients on both<br />

treatment and cancer control protocols.<br />

° The establishment of SJMHS leadership in cancer<br />

clinical trials research has been extraordinary<br />

under the leadership of Philip J. Stella, MD, Medical<br />

Director. With the vision to develop a leadingedge<br />

program, Dr. Stella and staff put in place the<br />

elements needed to become a National Cancer<br />

Institute funded Community Clinical Oncology<br />

Program. The Ann Arbor Regional CCOP was<br />

formed, receiving NCI support commencing in<br />

1994. Since that time, a total of 11 other Michigan<br />

health systems and one Connecticut hospital have<br />

joined what is now the Michigan Cancer Research<br />

Consortium CCOP (MCRC CCOP) -- renamed to<br />

better reflect its membership. SJMHS has been the<br />

fiscal agent for the CCOP since its inception; Dr.<br />

Stella has been the Principal Investigator this entire<br />

time. In 2009, over 600 patients were enrolled<br />

in research studies, and 2,000+ individuals on<br />

studies are being followed each year. The MCRC<br />

CCOP has achieved a national reputation for<br />

quality research and has been funded by the NCI<br />

continuously since 1994. It is one of the largest<br />

CCOPs in the country.<br />

° The original vision for the Robert H. and Judy Dow<br />

Alexander Cancer Care Center was to provide all<br />

oncology services in one location and to establish<br />

“clinics” where physicians of many disciplines<br />

would come to the patient to coordinate the<br />

diagnostic and treatment processes. Our original<br />

hope was to develop multidisciplinary clinics<br />

for the several major cancer diagnoses: breast,<br />

colon, lung and prostate malignancies. Not only<br />

do we have multidisciplinary physician groups<br />

for each of these disease sites, but we have them<br />

for gastrointestinal, genitourinary, gynecologic,<br />

neurologic, endocrine, head and neck, and<br />

cutaneous malignancies. This has become our<br />

model of care.<br />

° In 1993, our measurements related to the quality<br />

of care we were providing utilized data from<br />

our Tumor Registry and compared our data with<br />

that of other hospital tumor registries. We were<br />

able to review such things as stage of disease<br />

at diagnosis, numbers of patients enrolling in<br />

clinical trials, and morbidity and mortality data.<br />

Over the years we chose to participate in the<br />

multiple cancer quality databases as they<br />

became available so as to develop one of the<br />

most comprehensive and far-reaching quality<br />

programs in existence today. These databases<br />

include the National Comprehensive Cancer<br />

Network (NCCN) Breast Cancer Database, the<br />

Quality Oncology Physician Initiative (QOPI)<br />

sponsored by the American Society of Clinical<br />

Oncology (ASCO), the Society of Thoracic<br />

Surgeons Database, the Blue Cross & Blue<br />

Shield of Michigan Pathways Project, and the<br />

American College of Surgeons Tumor Registry.<br />

We clearly want to know how our care compares<br />

with that around the country and “continuous<br />

improvement” is a framework which we embrace.<br />

° One of our most recent and most exciting<br />

accomplishments occurred in April 2010 when<br />

the SJMHS cancer program was awarded a<br />

$2.5 million NCI Community Cancer Centers<br />

Program (NCCCP) grant. This grant program is<br />

competitive and SJMHS was among<br />

only 14 sites selected from applications across<br />

the country. Funding for this program comes<br />

from the American Recovery and Reinvestment<br />

Act; and the funds will support eleven oncology<br />

program positions including genetics coordinator,<br />

continuum of care coordinator, and additional<br />

nurse navigators among others. It supports<br />

methods to reduce healthcare disparities and<br />

improve access to clinical trials. It is discussed<br />

in more detail later in this report.<br />

° In mid-2009, SJMHS was notified that the<br />

oncology program was awarded $199,000<br />

to be utilized through August 2011 to fund<br />

two Nurse Navigator positions that focus on<br />

education related to clinical trials as well as<br />

actual recruitment to research studies. This<br />

funding, too, comes via the National Institutes<br />

of <strong>Health</strong> and the American Recovery and<br />

Reinvestment Act and is designed to both<br />

accelerate and promote scientific research<br />

and allow for job creation and retention.<br />

2010 Annual Cancer Report • 5


FOUNDATIONS OF CANCER CARE<br />

American College of Surgeons’<br />

Commission on Cancer: Teaching<br />

Hospital Cancer Program<br />

Originating in 1922 by the American College<br />

of Surgeons’ (ACoS), the Commission on<br />

Cancer establishes standards to ensure quality,<br />

multidisciplinary, and comprehensive cancer care<br />

delivery. Accreditation by the Commission on<br />

Cancer (CoC) is granted only to those organizations<br />

that have voluntarily committed to provide the best<br />

in cancer diagnosis and treatment and are able<br />

to comply with established CoC standards. These<br />

standards ensure that a full range of state-of-the-art<br />

diagnostic, treatment, and supportive services are<br />

offered at accredited facilities.<br />

St. <strong>Joseph</strong> <strong>Mercy</strong> Hospital and the SJMH Cancer<br />

Program have been accredited by the Commission<br />

on Cancer since 1986, receiving accreditation<br />

with commendation in 2007 as a Teaching Hospital<br />

Cancer Program. A rigorous evaluation and review<br />

of our performance and compliance with CoC<br />

standards will again be conducted in 2010.<br />

Cancer Program Overview<br />

<strong>Saint</strong> <strong>Joseph</strong> <strong>Mercy</strong> <strong>Health</strong> <strong>System</strong> (SJMHS) is one<br />

of the most advanced providers of comprehensive<br />

cancer care in Michigan with three patient-centered,<br />

dedicated cancer centers and a fourth one soon to<br />

open. Our multidisciplinary approach provides highquality<br />

patient outcomes that are based on leadingedge<br />

research and clinically proven therapies.<br />

Newly-diagnosed cancer patients average 2,400<br />

each year (see Appendix A, Tumor Registry 2009<br />

Analytic Cases by Diagnostic Site).<br />

Integral to the SJMHS oncology program is a full<br />

spectrum of interdisciplinary caregivers who are<br />

highly experienced and passionate about their<br />

work. Chemotherapy certified nurses in Ann Arbor<br />

provide infusion services to an average of 65 patients<br />

per day. Oncology social workers are available for<br />

individual and family counseling at all phases of the<br />

cancer experience; they also lead numerous support<br />

groups which have been a mainstay of our program<br />

for 25+ years. The Palliative Care Team works across<br />

all settings, developing and implementing plans for<br />

care when comfort is the goal. Nurse navigators,<br />

home care case managers, dieticians, pastoral<br />

care chaplains and hospice staff are key members<br />

of the oncology team to ensure we address the<br />

comprehensive needs of our patient population.<br />

2009 Program Statistics<br />

Topic<br />

Data Point<br />

Newly Diagnosed Cancer Patients 2,448<br />

Radiation Treatments Delivered 24,85<br />

CyberKnife ® Fractions Delivered 614<br />

Chemotherapy & Infusion Treatments 18,847<br />

Mammograms Performed 54,000<br />

GI Endoscopies Performed 16,000<br />

Lung Cancer Surgical Cases 477<br />

# of Patients Enrolled in Clinical Trials since 2005 1,300<br />

6 • 2010 Annual Cancer Report


Additional Cancer<br />

Centers Opened<br />

November 2009<br />

St. Joesph <strong>Mercy</strong> Canton<br />

Cancer Center<br />

May 2006<br />

St. Joesph <strong>Mercy</strong> Brighton<br />

Cancer Center<br />

Facilities<br />

Opened in 1993, the Robert H. and Judy Dow<br />

Alexander Cancer Care Center (also known as<br />

St. <strong>Joseph</strong> <strong>Mercy</strong> Cancer Care Center) at St. <strong>Joseph</strong><br />

<strong>Mercy</strong> Hospital in Ann Arbor was a leader in cancer<br />

center design, focusing on the inclusion of all<br />

outpatient services under one roof. It is a 45,000+<br />

square foot outpatient facility housing radiation<br />

oncology, a large chemotherapy/infusion clinic,<br />

laboratory, medical and gynecologic oncology<br />

physician offices, the Michigan Cancer Research<br />

Consortium CCOP operations office, and oncology<br />

program administration. Multidisciplinary clinic<br />

space affords patients the opportunity to be evaluated<br />

by all oncology physician specialists in one<br />

setting. The Radiation Oncology Department houses<br />

Michigan’s first Cyberknife ® Radiosurgery Center<br />

and a dedicated brachytherapy surgical suite.<br />

This outpatient cancer center links to the new St.<br />

<strong>Joseph</strong> <strong>Mercy</strong> Hospital with a 60,000 square-foot<br />

Surgery Pavilion, incorporating 17 surgical suites<br />

equipped for the latest minimally invasive procedures.<br />

A beautiful 30-bed inpatient oncology unit<br />

located on the eleventh floor offers a panoramic<br />

view of the surrounding countryside.<br />

Two additional cancer centers provide comprehensive<br />

care to patients in the SJMHS service area. In May<br />

2006, SJMHS opened the $13.6 million Warren R. &<br />

Lauraine A. Hoenshield Cancer Center (also known<br />

as St. <strong>Joseph</strong> <strong>Mercy</strong> Brighton Cancer Center),<br />

20 miles north of Ann Arbor. This is one of the<br />

fastest growing communities in the state, and this<br />

Center houses the only linear accelerator in<br />

Livingston County. Prior to its opening, patients undergoing<br />

radiation therapy drove an average of 40<br />

minutes to a treatment facility. The chemotherapy<br />

treatment area includes 15 treatment bays. Each bay<br />

overlooks a healing garden with bright, modern-looking<br />

sculptures. The first bay is considered a retreat<br />

area where patients can play cards, games or work<br />

on computers. The design team consulted with both<br />

patients and employees throughout the project<br />

which has resulted in a cancer center with a healing<br />

environment of soothing colors, water fountains,<br />

murals and original artworks.<br />

The new St. <strong>Joseph</strong> <strong>Mercy</strong> Canton Cancer Center<br />

in Canton, Michigan opened in late November 2009.<br />

This facility duplicates the St. <strong>Joseph</strong> <strong>Mercy</strong> Brighton<br />

Cancer Center described above, offering both chemotherapy<br />

and radiation oncology services. Plans<br />

are underway to open a fourth cancer treatment<br />

center in Chelsea, Michigan within the next year.<br />

2010 Annual Cancer Report • 7


FOUNDATIONS OF CANCER CARE (con’t)<br />

Oncology Physician Specialists<br />

Medical Oncology<br />

Medical oncologists/hematologists are the<br />

mainstay for cancer treatment and most often are<br />

the coordinators of the comprehensive care required<br />

by oncology patients. At SJMH, two new physicians<br />

came on board in 2009 for a total of 11 medical<br />

oncologists in three physician practices. All<br />

participate in clinical trials through the Michigan<br />

Cancer Research Consortium and are the lead<br />

accruers to study protocols. In addition, they provide<br />

leadership to the multiple tumor boards where<br />

patient cases are presented for input and direction<br />

from a group of multispecialty physicians.<br />

2009 Critical Review Cases<br />

Tumor Board<br />

Cases<br />

Ann Arbor<br />

General (Includes Lung, GI) 155<br />

Breast Cancer 272<br />

Genitourinary Cancers 28<br />

Head & Neck Tumors 80<br />

Livingston 59<br />

The medical oncologists at SJMHS participate in all<br />

multidisciplinary clinics and interdisciplinary advisory<br />

groups. In the past year they presented a total of<br />

seven grand rounds for the Department of Medicine.<br />

They provide program leadership in multiple areas<br />

including membership on the SJMHS Oncology<br />

Institutional Review Board and various quality<br />

improvement initiatives.<br />

Medical oncologists oversee the chemotherapy<br />

infusion clinics in all cancer centers. They worked<br />

closely with nursing staff this year to evaluate the<br />

safety of chemotherapy ordering and administration<br />

at SJMHS and undertook steps to develop/refine the<br />

chemotherapy physician order entry system. Over<br />

16,000 chemotherapy doses were analyzed with<br />

only 17 errors (0.1%) that reached the patient; none<br />

of these had negative outcomes for the patient. The<br />

Oncology & Infusion Services Collaborative Practice<br />

Team is currently working on standardized chemotherapy<br />

order forms, with 17 presently in place.<br />

During 2009, the following guidelines were<br />

created/revised and implemented:<br />

° Management of Tumor Lysis Syndrome<br />

° Guidelines for Use of Antiemetics in the Adult<br />

Patient Receiving Chemotherapy<br />

° Guidelines for the Administration of Immune<br />

Globulin (Intravenous)<br />

2009 Chemotherapy and Infusion Volumes<br />

Ann Arbor<br />

Brighton<br />

Chemotherapy 7631 2234<br />

Blood Transfusions 239 158<br />

Other Infusions 5698 2920<br />

8 • 2010 Annual Cancer Report


Radiation Oncology<br />

Radiation oncology services are available in the St. <strong>Joseph</strong> <strong>Mercy</strong> Cancer Care Center (Ann Arbor) and<br />

both the Brighton and Canton facilities. Walter Sahijdak, MD, Medical Director, and five radiation oncologists<br />

provide expertise in the full spectrum of radiation therapy services.<br />

In 2007, SJMHS unveiled the first CyberKnife ® in Michigan. CyberKnife ® represents the latest generation of<br />

radiosurgery systems, combining image guidance technology with a compact linear accelerator. It has the<br />

flexibility to move in three dimensions to focus on the targeted area for treatment practically anywhere in the<br />

body. It has demonstrated success with a wide spectrum of cancers including brain, lung, prostate, pancreas,<br />

liver, and head/neck. The very precise radiation treatment can pinpoint and destroy tumors deep inside the<br />

body with no incisions, minimal side effects, no pain, and immediate return to normal activity.<br />

SJMHS has one of the few dedicated brachytherapy surgical suites in North America, offering both highdose-rate<br />

(HDR) and low-dose-rate (LDR) brachytherapy treatments for prostate, gynecologic, head/neck<br />

and breast cancers.k and breast ca<br />

2009 Radiation Oncology Patient<br />

Volumes & Services<br />

Ann Arbor<br />

Brighton<br />

New Patient Consults 958 251<br />

Radiation Treatments 17,876 6,975<br />

CyberKnife ® Consults 87 N/A<br />

CyberKnife ® Fractions 614 N/A<br />

High-Dose-Rate Brachytherapy 157 N/A<br />

2010 Annual Cancer Report • 9


FOUNDATIONS OF CANCER CARE (con’t)<br />

The daVinci ® Robotic Surgical <strong>System</strong> is designed<br />

to enable complex surgery using a very precise,<br />

minimally invasive approach. We were the first<br />

Michigan hospital to routinely utilize the system for<br />

complex thoracic and cardiac surgery.<br />

Surgical Oncology<br />

The American College of Surgeons ranks SJMHS<br />

among the best cancer care providers in the United<br />

States. We have an expert team of respected and<br />

experienced oncologic surgeons, with each<br />

specialty trained to treat specific malignancies:<br />

° Thoracic/Esophageal Tumors<br />

° Breast Cancer<br />

° Neurological Cancers (Brain, Spinal Cord)<br />

° Genitourinary Cancers (Renal, Prostate)<br />

° Cutaneous Cancers (Skin)<br />

° Hepatobiliary Malignancies (Liver, Pancreas)<br />

° Colorectal Cancer<br />

° Gynecologic Malignancies<br />

In 2007, SJMHS opened one of the most sophisticated<br />

surgery pavilions in the country at St. <strong>Joseph</strong> <strong>Mercy</strong><br />

Hospital, Ann Arbor. The all-new, 60,000 square-foot<br />

facility features 17 suites designed for minimally<br />

invasive procedures and equipped with the latest<br />

computer, image-driven technology, including the<br />

daVinci ® Robotic Surgical <strong>System</strong>. This robotic<br />

platform is designed to enable complex surgery<br />

using a very precise, minimally invasive approach.<br />

We were the first Michigan hospital to routinely utilize<br />

the daVinci ® system for complex thoracic and<br />

cardiac surgery.<br />

Multidisciplinary Clinics<br />

The St. <strong>Joseph</strong> <strong>Mercy</strong> cancer program has dedicated<br />

clinic space on the second floor of the Cancer<br />

Center in Ann Arbor. This spacious suite incorporates<br />

patient exam rooms as well as well as patient/family<br />

meeting rooms and large conference spaces. Multidisciplinary<br />

clinics are in place for the following areas:<br />

° Lung cancer<br />

° Breast cancer<br />

° Head and neck malignancies<br />

° Neuro-oncology diagnoses<br />

° Gastrointestinal cancers<br />

° All diagnoses requiring CyberKnife ® treatment<br />

(both intracranial and extra-cranial malignancies)<br />

The lung cancer multidisciplinary clinic is our most<br />

experienced and long-standing clinic which serves<br />

as the model for all other multidisciplinary clinics.<br />

10 • 2010 Annual Cancer Report


Multidisciplinary Care<br />

The overriding model for cancer care at St. <strong>Joseph</strong><br />

<strong>Mercy</strong> Cancer Center is the interdisciplinary Advisory<br />

Committees that have been established for breast<br />

cancer, lung cancer, gastrointestinal malignancies,<br />

genitourinary tumors, neurologic malignancies,<br />

gynecologic oncology, and head/neck cancers.<br />

Advisory Committees are charged with the<br />

development and oversight of the overall program<br />

and service delivery for their diagnostic sites. National<br />

Comprehensive Cancer Network Guidelines<br />

(NCCN) provide the framework for care. Committee<br />

membership is comprised of key physicians, nurse<br />

navigators, research nurses, administrators, and social<br />

workers. The Advisory Committees are responsible<br />

for the ongoing evaluation of their programs and the<br />

implementation of quality initiatives. Each committee<br />

includes a Nurse Navigator, which is discussed in<br />

greater detail in this report in the section “Coordination<br />

of Care.”<br />

Breast Cancer Program<br />

Breast care at SJMH is delivered in a comprehensive<br />

multidisciplinary program including all sectors of care<br />

from screening through breast cancer survivorship.<br />

Screening is performed through an all digital network<br />

with diagnostics performed at the Women’s <strong>Health</strong><br />

Center at SJMH-Ann Arbor and our outpatient centers<br />

in Chelsea and Brighton. Over 50,000 mammograms<br />

are performed yearly and read the same day by<br />

radiologists specializing in breast diagnostics.<br />

In addition to digital mammography the centers<br />

are equipped with breast MRI capability for screening<br />

high-risk women and performing MRI-guided biopsies.<br />

A training program has been developed and implemented<br />

following American College of Radiology<br />

guidelines to ensure expert interpretation of MRI<br />

exams. New state-of-the-art ultrasound equipment<br />

for core biopsies and diagnostic studies has been<br />

acquired and is currently being utilized in both the<br />

Ann Arbor and Brighton centers.<br />

Breast <strong>Health</strong> Specialists and a Breast Cancer Nurse<br />

Navigator ensure the seamless delivery of care and<br />

provide patient education and support. Navigators<br />

meet patients at the time of breast biopsy to assess<br />

patient needs if the biopsy is positive. They provide<br />

education related to surveillance of high-risk<br />

conditions noted by Pathology.<br />

Radiation oncology offers the most technologically<br />

advanced planning and treatment systems,<br />

including partial breast irradiation. Nationally<br />

accepted guidelines are followed for cancer care.<br />

A database through the Michigan Breast Oncology<br />

Quality Initiative, the National Comprehensive<br />

Cancer Network, and Quality Oncology Physician<br />

Initiative funded through Blue Cross Blue Shield of<br />

Michigan provide nearly real-time quality data to<br />

help with benchmarking and ensure compliance<br />

with guidelines.<br />

An Image Recovery Center was recently<br />

opened in the beautiful Inspirit Salon & Spa<br />

located in the retail space of the new St.<br />

<strong>Joseph</strong> <strong>Mercy</strong> Hospital in Ann Arbor. Full-time<br />

image recovery services and products are<br />

offered including prosthesis fittings, skin care<br />

and clothing items specific to the needs of<br />

breast cancer patients, head shaving, wigs<br />

and head scarves. The certified specialist<br />

working in this center personally visits all<br />

patients hospitalized after breast cancer<br />

surgery to provide assistance and assure<br />

the patient is aware of available resources.<br />

2010 Annual Cancer Report • 11


FOUNDATIONS OF CANCER CARE (con’t)<br />

Gastrointestinal (GI) Cancer Program<br />

The Gastrointestinal Cancer Program has evolved<br />

to become one of the premiere cancer care<br />

programs at SJMHS, encompassing multiple<br />

physician specialists who are recognized experts in<br />

their fields and cutting edge technology offered by<br />

only a few centers in the state. The following<br />

provides a brief overview of some of the important<br />

work being done by this outstanding team.<br />

Over 16,000 endoscopies are performed each year.<br />

Our managed care colorectal screening rate is 68%<br />

compared with 59% for southeast Michigan.<br />

The Department of Colorectal Surgery comprised of<br />

three colorectal surgeons pioneered the technique<br />

of laparoscopic colectomy and are currently at the<br />

forefront of minimally invasive surgery using the<br />

daVinci ® robotic surgical system. Robert Cleary, MD,<br />

has achieved the distinction of becoming the<br />

leading robotic colorectal surgeon in the Midwest.<br />

Another new area of expertise utilized by the<br />

colorectal surgeons is transendoscopic microsurgery<br />

or TEM. TEM allows the minimally invasive local<br />

excision of rectal tumors with the aid of a special<br />

operative rectoscope and magnified view. This<br />

technique is not widely available due to the necessary<br />

special instrumentation, unusual technical aspects<br />

of the approach, and stringent patient selection.<br />

Dr. Cleary has led the effort at SJMH to establish a<br />

colorectal surgery fellowship program,<br />

and our first fellow is expected in<br />

July 2011.<br />

The scholarly work of Naresh Gunaratnam, MD, has<br />

focused on two new minimally invasive techniques<br />

to combat the potentially progressive disease of<br />

Barrett’s Esophagus with or without high-grade<br />

dysplasia. Radiofrequency ablation (BARRX) utilizes<br />

energy to allow a limited depth of injury to destroy<br />

the Barrett’s cells without destroying the normal tissue<br />

in the deeper layers. Endoscopic Mucosal<br />

Resection (EMR) is a procedure that is available<br />

for removal of small nodules within the Barrett’s<br />

segment. EMR enables physicians to take a much<br />

larger biopsy specimen and offers the advantages<br />

of outpatient treatment. Both Dr. Gunaratnam and<br />

his colleague, Dr. Andrew Catanzaro, have<br />

successfully performed the BARRX and/or EMR<br />

procedures on over 45 patients with Barrett’s<br />

related dysplasia and adenocarcinoma. To date,<br />

five patients have completed treatment and<br />

show no residual dysplasia or cancer with up<br />

to three-year follow-up.<br />

Edward Kreske, MD, specializes in surgery of liver,<br />

pancreas and gallbladder. Minimally invasive<br />

techniques include laparoscopic pancreatic<br />

surgical resections, radiofrequency ablation for<br />

treatment of hepatocellular carcinoma and<br />

embolization in conjunction with the expertise<br />

of the interventional radiologists.<br />

The GI Cancer Program was one of the first workgroups<br />

at SJMH to embrace multidisciplinary care,<br />

which is evident in their progress and the fact that<br />

they are in the forefront of their field.<br />

Robert Cleary, MD and the<br />

daVinci Robotic Surgical <strong>System</strong><br />

12 • 2010 Annual Cancer Report


Lung Cancer Program<br />

Genitourinary Cancer Program<br />

Although the Genitourinary Cancer Advisory<br />

Committee oversees care of patients with<br />

tumors of the entire genitourinary system, a<br />

major focus of their work is in the field of prostate<br />

cancer. The Committee includes specialists in<br />

urology, radiation oncology, medical oncology,<br />

radiology and pathology.<br />

Over the past year, this group has<br />

accomplished the following:<br />

° Adoption of the National Comprehensive<br />

Cancer Network (NCCN) prostate cancer<br />

treatment guidelines that assures patients are<br />

educated about all recommended treatment<br />

options and are afforded the opportunity to<br />

consult with all appropriate specialists;<br />

° Prostate biopsy protocols were reviewed and<br />

standardized so that core biopsies performed<br />

in both the Urology and Radiology<br />

Departments include twelve core samples<br />

done with local anesthesia;<br />

° Educational resources for prostate cancer<br />

patients were developed and made available<br />

throughout urology offices as well as radiation<br />

and medical oncology areas.<br />

The multidisciplinary team offers a full range of<br />

treatment options that include robotic-assisted<br />

surgeries, brachytherapy (high dose rate [HDR];<br />

low dose rate [LDR]); intensity modulated<br />

radiation therapy (IMRT), and hormonal therapy.<br />

Additionally, SJMHS is currently participating<br />

in a “Prospective Evaluation of CyberKnife ®<br />

Stereotactic Radiosurgery for Low and<br />

Intermediate Prostate Cancer: Homogenous<br />

Dose Distribution.”<br />

The SJMH Pathology Department added its<br />

first fellowship-trained genitourinary pathologist,<br />

Matthew Wasco, MD, who had the opportunity<br />

to spend some time at the University of Indiana<br />

studying testicular pathology.<br />

In addition, the SJMH Pathology Department<br />

now offers a relatively new laboratory test,<br />

Fluorescence in situ hybridization (FISH), to<br />

detect bladder cancer through analysis of<br />

chromosomal abnormalities in urine.<br />

Over the last few years, lung cancer treatment has<br />

transitioned toward minimally invasive techniques and<br />

expanding the role of robotic surgery. Additionally, the<br />

field of video-assisted thoracoscopic surgery (VATS)<br />

has evolved from experience with laparo-scopic<br />

procedures. Advanced video technology, computers<br />

and high-tech electronics are utilized to perform many<br />

operations that formerly required large, open incision<br />

thoracotomy.<br />

Other technologic advances are also changing the<br />

scope of lung cancer treatment. With the addition of<br />

the new Cyberknife ® , we are now able to offer curative<br />

therapy to those patients who are not good surgical<br />

candidates due to pulmonary function or other medical<br />

comorbidities. We have obtained the superDimension ®<br />

Electromagnetic Navigation Bronchoscopy system<br />

designed to extend the reach of the conventional<br />

bronchoscope, providing minimally invasive access to<br />

lesions deep in the lungs as well as mediastinal lymph<br />

nodes. Using GPS-like navigation, this system enables<br />

physicians to make early diagnoses of benign and<br />

malignant lung lesions.<br />

SJMHS is participating in an International Randomized<br />

Study to Compare CyberKnife® Stereotactic Radiotherapy<br />

with Surgical Resection in Stage I Non-Small<br />

Cell Lung Cancer (STARS). Sites from around the world<br />

are participating in this 1,200-patient study, with<br />

coordination and oversight by the MD Anderson<br />

Cancer Center team. In addition, we have developed<br />

a cryotherapy program that facilitates treatment<br />

of endobronchial tumors and maintenance of<br />

airway patency.<br />

The above describes cutting-edge approaches to lung<br />

cancer treatment. However, as we view the continuum<br />

of care, we are working diligently to develop initiatives<br />

that address the area of prevention. We are especially<br />

proud of a smoking cessation program that we are<br />

implementing in offices of primary care physicians<br />

called “Tackle Tobacco.” This program is based<br />

on the U.S. Department of <strong>Health</strong> and Human Services<br />

Clinical Practice Guidelines: Treating Tobacco Use<br />

and Dependence (2008), which provides an evidencebased<br />

framework. “Tackle Tobacco” is a system-wide<br />

“train the trainer” program in which an office<br />

“champion” is educated regarding tobacco addiction,<br />

“quit” products, motivational interviewing, methods/<br />

tools to assess smoking behaviors, and counseling<br />

strategies to assist patients to discontinue smoking.<br />

Office “champions” are also charged with the<br />

development of a plan to ensure compliance with<br />

this program in their office practices.<br />

Vita Sullivan, MD has been the Medical Director of Thoracic<br />

Oncology since 2006. Dr. Sullivan completed her medical<br />

education at the University of Chicago. She did her General<br />

Surgery Residency at St. <strong>Joseph</strong> <strong>Mercy</strong> Hospital, Ann Arbor,<br />

MI and her Fellowship in Cardiothoracic Surgery at the<br />

University of Minnesota, Minneapolis, MN.<br />

2010 Annual Cancer Report • 13


FOUNDATIONS OF CANCER CARE (con’t)<br />

Gynecologic Oncology Program<br />

Gynecologic oncology practice is joining with<br />

scientific experts to deliver minimally invasive surgery<br />

for staging of endometrial cancer. Robot-assisted<br />

surgery with the da Vinci ® Surgical <strong>System</strong> is<br />

accomplished by our surgeons through tiny, 1-2<br />

centimeter incisions; this provides greater precision<br />

and control, minimizing the pain and risk associated<br />

with large incisions while increasing the likelihood of<br />

a fast recovery and excellent clinical outcomes.<br />

Head & Neck Malignancies<br />

Head and neck tumors include those that arise in<br />

the nasal cavity, sinuses, lips, oral cavity, salivary<br />

glands, throat, or larynx. They comprise 3-5% of all<br />

cancers nationally, and average about 2% of all new<br />

cancer diagnoses at SJMH. The multidisciplinary<br />

team working with this patient population includes<br />

otolaryngologists, radiation oncologists, medical<br />

oncologists, plastic surgeons, pathologists, and<br />

speech therapists.<br />

Although not a new practice, intraperitoneal (IP)<br />

chemotherapy has become a standard of care<br />

for women fighting gynecologic cancers within the<br />

peritoneal cavity. Collaboration with our interventional<br />

radiologist for the insertion of abdominal ports for<br />

IP chemotherapy has eliminated the need for<br />

patients to return to the operating room following<br />

a diagnosis of cancer. This alliance has saved<br />

patients a surgical procedure and improved<br />

recovery time while allowing for an expedited<br />

initiation of IP chemotherapy.<br />

The gynecologic oncologists at SJMHS participate in<br />

national Gynecologic Oncology Group clinical trials<br />

through the Michigan Cancer Research Consortium<br />

CCOP. In addition, investigator-initiated studies are<br />

implemented when they are deemed appropriate<br />

for the SJMHS population. One such study currently<br />

underway surveys gynecologic oncology patients<br />

to measure distress during cancer treatment; results<br />

will be shared with oncology program physicians<br />

and staff.<br />

Neurologic Cancers (Brain, Spinal Cord)<br />

The advent of the CyberKnife ® has had a tremendous<br />

impact on the treatment of brain and spinal cord<br />

tumors. SJMH neurosurgeon Georffrey M. Thomas, MD,<br />

was the first neurosurgeon in Michigan to perform<br />

pain-free CyberKnife ® radiosurgery. Using this<br />

revolutionary technology, he is able to “target”<br />

benign and malignant tumors of the brain and spine<br />

with extreme accuracy. Having just completed our<br />

third year of treating patients with the CyberKnife ® ,<br />

data show that for brain and spine cases we have<br />

treated 13 malignant and 36 non-malignant tumors.<br />

The head and neck surgeons at St. <strong>Joseph</strong> <strong>Mercy</strong><br />

Hospital in Ann Arbor are among the first in the<br />

country to offer Trans-Oral Robotic Surgery (TORS)<br />

for their patients. TORS is a minimally invasive<br />

surgical treatment for diseases of the head and<br />

neck. The robotic instruments provide the surgeon<br />

with unsurpassed visualization, precision, dexterity<br />

and control. For head and neck cancer surgery,<br />

the advantages are much faster recovery, decreased<br />

need for feeding tubes, and no scar. TORS is FDA<br />

approved for excision of tumors of the tongue,<br />

tonsils and larynx (voice box). Potential benefits<br />

of TORS include the avoidance of disfiguring surgery,<br />

minimizing or eliminating the need for chemotherapy<br />

or radiation therapy, avoiding tracheotomy, quicker<br />

return to normal speech and swallowing, less pain,<br />

shorter recovery time, and minimal scarring.<br />

Endocrine Cancers (Thyroid)<br />

The major focus of the Endocrine Cancers Advisory<br />

Committee has been in the area of the diagnosis<br />

and treatment of thyroid cancer. The Committee<br />

has standardized treatment guidelines for thyroid<br />

cancers. Of importance has been their work to<br />

correlate the fine needle aspiration biopsy results<br />

with the subsequent surgical outcomes, ensuring<br />

that the pre-surgical biopsy results correlate with<br />

the surgical pathology; results have been excellent,<br />

with no false positive results.<br />

Of note is the increased utilization of Thyrogen<br />

scanning (and treatment as applicable) in patients<br />

with certain types of thyroid cancer. The use of<br />

Thyrogen is an alternative to thyroid hormone<br />

withdrawal and is more convenient for patients.<br />

14 • 2010 Annual Cancer Report


Skin Cancers (Melanoma)<br />

The Academic Dermatology Residency is in its fifth<br />

year. We currently have 11 residents in our three-year<br />

program. All have presented at national meetings<br />

including the American Academy of Dermatology.<br />

SJMH medical staff dermatologists and dermatology<br />

residency dermatologists remove hundreds of skin<br />

cancers per year including both melanoma and<br />

non-melanoma lesions (squamous cell carcinomas<br />

and basal cell carcinomas).<br />

Cutaneous T Cell lymphoma patients are cared for<br />

by Dr. David Fivenson.<br />

Areas of research over the past two years include<br />

new TMN (tumor-metastases-node) and pathologic<br />

classification of malignant melanoma as well as new<br />

protocols for treatment of melanoma and Merkel<br />

cell carcinoma.<br />

The focus of the cutaneous malignancy program<br />

has been on establishing state-of-the-art care<br />

for individuals with various skin cancers. Key<br />

accomplishments in this area include implementation<br />

of a Mohs Micrographic Surgery clinic at SJMH<br />

and the development of sentinel node testing for<br />

malignant melanoma. Close collaboration between<br />

the dermatopathologists and plastic surgeons<br />

has resulted in excellent cure rates and minimum<br />

disfiguration for non-melanoma skin cancers<br />

using frozen section control to treat the malignancies.<br />

Mohs surgery for non-melanoma skin cancers is<br />

performed by three Mohs surgeons on the SJMH<br />

staff: Drs. Craig Cattell, Montgomery Gillard and<br />

Kent Krach. The sentinel lymph node biopsy program<br />

for advanced melanomas is expanding at SJMH<br />

with the addition of Dr. Ian Lytle, plastic surgeon;<br />

he is performing sentinel lymph node biopsies<br />

on deeper melanoma cases.<br />

Our second annual free skin cancer<br />

screening at SJMH was held in<br />

May 2010, with screening of over<br />

100 individuals. Both melanoma<br />

and non-melanoma skin cancers<br />

were detected in participants.}<br />

2010 Annual Cancer Report • 15


CANCER RESEARCH<br />

Michigan Cancer Research Consortium<br />

Community Clinical Oncology Program<br />

Since its inception in 1983, the Community Clinical<br />

Oncology Program (CCOP) of the National Cancer<br />

Institute has linked community cancer specialists to<br />

NCI-supported research to conduct approved<br />

cancer treatment, prevention, and control clinical<br />

trials. Types of studies carried out have broadened<br />

from treatment to chemoprevention, symptom<br />

management, continuing care, and quality of life.<br />

By far, the majority of cancer care is provided in the<br />

community setting; therefore, it is imperative that<br />

those patients and families have access to the most<br />

current and innovative treatment that is available<br />

through clinical trials programs. To this end, the<br />

oncology program at SJMHS initiated its research<br />

program in 1988.<br />

St. <strong>Joseph</strong> <strong>Mercy</strong> <strong>Health</strong> <strong>System</strong> first received<br />

funding for its clinical trials program from the<br />

National Cancer Institute in 1994 and has been<br />

funded continuously since that time. Originally<br />

established as the Ann Arbor Regional CCOP, its<br />

growth has been phenomenal under the steadfast<br />

leadership of Philip J. Stella, MD, principal<br />

investigator since the program’s inception. A name<br />

change better reflected its expansion to include its<br />

current 12 Michigan hospitals and one Connecticut<br />

hospital as well as over 100 medical oncologists,<br />

radiation oncologists, surgeons and other specialists.<br />

The MCRC CCOP received over $1.5 million in<br />

funding support in 2009 to maintain the infrastructure<br />

necessary to implement one of the country’slargest<br />

and most respected community research programs.<br />

The dollars support over 20 research staff of nurses,<br />

regulatory specialists, data managers, laboratory<br />

coordinators, a research pharmacist and program<br />

accountant.<br />

As one of 47 CCOP research programs currently<br />

sponsored by the NCI, the MCRC-CCOP has<br />

established a stellar reputation for quality research<br />

practices and patient accrual.<br />

The following highlights key accomplishments:<br />

° The MCRC-CCOP has received over $15 million in<br />

grant support from the NCI since 1994;<br />

° At any given time, over 120 treatment and cancer<br />

control studies are open and available for patient<br />

accrual;<br />

° Over 600 patients are placed on clinical trials<br />

each year, with SJMH patients comprising half of<br />

that total;<br />

° At any given time over 2,000 patients are being<br />

followed on protocols to which they were enrolled<br />

in previous years (e.g., long-term follow-up);<br />

° The MCRC CCOP received the prestigious<br />

American Society of Clinical Oncology Clinical<br />

Trials Participation Award (2006) for its demonstrated<br />

outstanding “commitment to improving the care<br />

of people with cancer through increased<br />

participation in clinical trials.”<br />

16 • 2010 Annual Cancer Report


CARE ACROSS<br />

THE CONTINUUM<br />

National Cancer Institute Community<br />

Cancer Centers Grant (NCCCP)<br />

In 2009, SJMHS applied for and received the<br />

prestigious NCI Community Cancer Centers<br />

Program (NCCCP) grant with funding of $2.5 million<br />

over two years. This grant program is competitive,<br />

and SJMHS was among only 14 sites selected from<br />

applications across the country. This program is a<br />

strategic partnership of the NCI and participating<br />

hospitals designed to create a community-based<br />

cancer center network to support cancer research<br />

and enhance access to quality care at community<br />

hospitals. It began as a pilot program in 2007 as a<br />

network of community hospital cancer centers<br />

working to provide the most current, researchbased<br />

cancer care spanning the full cancer<br />

continuum with an emphasis on minority and<br />

underserved populations.<br />

Funding for this program comes from the American<br />

Recovery and Reinvestment Act and, therefore, will<br />

support the hiring of individuals to address the<br />

seven major focus areas designed to:<br />

° Reduce cancer health disparities<br />

° Improve quality of care at community hospitals<br />

° Increase participation in clinical trials<br />

° Enhance cancer survivorship and palliative<br />

care services<br />

° Participate in biospecimen research initiatives to<br />

support personalized medicine<br />

Nurse Navigators<br />

The Nurse Navigator role has existed at St. <strong>Joseph</strong><br />

<strong>Mercy</strong> Cancer Care Center for over ten years.<br />

Initial collaboration with the Women’s <strong>Health</strong><br />

Program supported the hiring of a nurse navigator<br />

for our breast cancer population. Being at<br />

the forefront of this concept, we needed to<br />

demonstrate the value of this role to physicians<br />

who believed their office staff provided all of the<br />

assistance required by women with breast cancer.<br />

However, patients readily embraced the direction,<br />

information and support offered by the nurse<br />

navigator as they traversed the health care system.<br />

Today there is no question as to the invaluable<br />

role nurse navigators play in the oncology field.<br />

In spring 2009, the Michigan Cancer Research<br />

Consortium CCOP applied for and received<br />

Administrative Supplement funding under the<br />

American Recovery and Reinvestment Act (2009)<br />

for the hiring of an Oncology Research Nurse<br />

Navigator (ORNN). The ORNN links with<br />

all newly-diagnosed patients to facilitate their<br />

transition to treatment with an important focus<br />

on considering a treatment plan that incorporates<br />

clinical trials.<br />

With the NCCCP award, the Office of Nurse<br />

Navigators was formalized in fall 2009 and is now<br />

comprised of four full-time and one part-time<br />

nurse navigator who work with all of the surgeons,<br />

medical oncologists and radiation oncologists so<br />

that all patients are contacted shortly after they<br />

are notified by their physician of their cancer<br />

diagnoses.<br />

° Expand use of electronic health records and<br />

connect to cancer research data network<br />

° Enhance cancer advocacy<br />

<strong>Saint</strong> <strong>Joseph</strong> <strong>Mercy</strong> <strong>Health</strong> <strong>System</strong><br />

clinical nurse navigators that assist<br />

our patients through oncology<br />

services: left to right – Lara Blair,<br />

Pam Ceo, Sharon Petri, Colleen<br />

Sweetland and Jennifer Bailey.<br />

2010 Annual Cancer Report • 17


CARE ACROSS THE CONTINUUM (con’t)<br />

Community Partnerships<br />

Both the American Cancer Society (ACS) and The<br />

Wellness Community have a major presence in our<br />

community. Our 25-year relationship with the<br />

American Cancer Society covers a broad spectrum<br />

of involvement including ACS community and state<br />

Board representation by SJMHS oncologists, Cancer<br />

Center administrators, and social workers; long-term<br />

(20+ years) collaboration in the presentation of<br />

patient support programs including “Look Good . . .<br />

Feel Better;” co-sponsoring of survivor events such<br />

as “Making Strides Against Breast Cancer;” and<br />

participation in fundraising activities.<br />

Our current partnership with ACS extends to<br />

implementation of the ACS Cancer Resource<br />

Centers at both the Ann Arbor and Brighton cancer<br />

centers. ACS volunteers work with patients at these<br />

facilities to assess needs that can be met through<br />

ACS resources. This has resulted in over 518 referrals<br />

for ACS services in 2009. SJMHS is the most involved<br />

and active health system in partnership with the ACS<br />

in southeastern Michigan.<br />

SJMHS is committed to “walk the talk” when it<br />

comes to working with community agencies for the<br />

benefit of oncology patients and families. To that<br />

end, SJMHS has made the commitment to donate<br />

land on its 341-acre campus for the construction<br />

of an American Cancer Society Hope Lodge.<br />

Hope Lodge offers free lodging for patients and<br />

caregivers who live outside the area and are<br />

receiving treatments or undergoing clinical trials<br />

at SJMHS. ACS is currently developing its timeline<br />

for this important project.<br />

Over the past three years, The Wellness Community<br />

of Southeast Michigan has become the major<br />

provider in our service area of support and<br />

educational services for cancer patients, families,<br />

and friends. All services are free for participants.<br />

Located in Ann Arbor, MI, it began as a grass roots<br />

organization that was started locally by a group of<br />

committed community volunteers who were each<br />

personally touched by cancer. Linda Langmore,<br />

MSW, oncology social worker in the St. <strong>Joseph</strong><br />

<strong>Mercy</strong> Cancer Center, was one of the organization’s<br />

founding members.<br />

The Wellness Community offers a comprehensive<br />

array of educational programs and workshops which<br />

are often provided by SJMHS oncologists, nurses, and<br />

other health care providers. For example, a class<br />

entitled “Frankly Speaking About Advanced Breast<br />

Cancer” was presented in October 2009 by Elaine<br />

Chottiner, MD, medical oncologist at SJMHS. Wellness<br />

Community brochures and events calendars are<br />

placed in the waiting rooms of all cancer center<br />

departments as well as physician offices.<br />

<strong>Health</strong> Disparities<br />

We will have no difficulty directing almost 40% of<br />

NCCCP project funding to disparities initiatives.<br />

An NCCCP award allows us to build on the successes<br />

we have had by:<br />

° Hiring a Manager of the <strong>Health</strong>care Disparities<br />

Program whose sole focus is the planning,<br />

implementation and evaluation of a cancerfocused<br />

program addressing the myriad of needs<br />

of patients and families who comprise minority,<br />

underserved, and uninsured persons.<br />

° Expanding our social services programs and<br />

staff to focus on the needs of minority and socioeconomically<br />

disadvantaged patients and<br />

families;<br />

° Enlisting a dedicated oncology patient financial<br />

services counselor to work with our<br />

socioeconomically disadvantaged population;<br />

° Expanding our network of African-American<br />

churches in the SJMH service area;<br />

° Initiating linkages with area churches that are<br />

building their Hispanic congregations (e.g., First<br />

United Methodist Church, Ypsilanti, MI; St. Mary’s<br />

Student Chapel, Ann Arbor, MI);<br />

° Establishing linkages with the ever-growing Asian<br />

populations in Washtenaw and Wayne Counties;<br />

° Expanding the MCRC CCOP’s minority-directed<br />

community education programs related to the<br />

NCI clinical trials program.<br />

18 • 2010 Annual Cancer Report


Biospecimen Research Initiatives<br />

The NCCCP award allows us to make significant<br />

progress toward the implementation of the NCI Best<br />

Practices for Biospecimen Resources program. We<br />

have the full support of Samuel Hirsch, MD, Chief<br />

of Pathology, and Drs. Paul Valenstein and <strong>Joseph</strong><br />

Tworek who have assumed responsibility for this<br />

project. Our experience in the collection and<br />

submission of both blood and tissue samples is<br />

significant through our clinical trials program. Many<br />

NCI clinical trials require specimen collection; other<br />

studies offer pharmacodynamic and pharmacokinetic<br />

testing as optional. The Michigan Cancer<br />

Research Consortium CCOP’s participation in these<br />

optional studies approaches 98%, establishing the<br />

framework for SJMHS leadership in the Biospecimen<br />

Research Initiative.<br />

Our work in the area of biospecimen research is<br />

a component of the National Cancer Institute’s<br />

Translational Research Program. The mission of<br />

the Translational Research Program is to integrate<br />

scientific advancements in the understanding of the<br />

biology of human cancer with the development of<br />

new interventions for the prevention, diagnosis, and<br />

treatment of cancer patients or populations at risk<br />

for cancer – and to speed up the process in order<br />

that promising new cancer discoveries can be<br />

translated into new interventions for patients faster.<br />

This is a particularly critical element for the future<br />

of oncology care and one to which we are<br />

strongly committed.<br />

Cancer Survivorship and<br />

Palliative Care Services<br />

Palliative Care is an approach to health care<br />

that focuses on relief of suffering and symptom<br />

management rather than on curing disease. It is<br />

designed to help provide the highest quality of<br />

life possible for people with illnesses that cannot be<br />

cured or conditions that are life-limiting. The Palliative<br />

Care Program at SJMH is staffed by a team of<br />

physicians, nurses, social workers, and pastoral care<br />

professionals, all skilled in symptom management<br />

and end-of-life care. They assist in the design and<br />

implementation of comprehensive care plans that<br />

include all aspects of patients’ and families’<br />

needs at this very critical time.<br />

The SJMHS oncology program developed a<br />

role which spans the entire continuum from the<br />

outpatient infusion area and inpatient units to the<br />

patients’ homes. Chaplain David McNeil has defined<br />

the continuum of care to mean any and all places<br />

where patients and families exist. He goes wherever<br />

needed. Home visits are common. He is often at<br />

the bedside when a patient dies. Chaplain McNeil<br />

performed numerous funeral services in the past<br />

year for those patients without a church home.<br />

We are fortunate to have this role and a remarkable<br />

man to fill it who embodies the word “continuum”<br />

as no other has done.<br />

Chaplain David McNeil has defined the<br />

continuum of care to mean any and all<br />

places where patients and families exist.<br />

He goes wherever needed.<br />

2010 Annual Cancer Report • 19


PATIENT CENTEREDNESS<br />

Oncology Patient Advocates Team<br />

Initiated in June 2008, the Oncology Patient Advocates<br />

Team links with cancer center patients and families<br />

to develop and implement plans to enhance the<br />

patient experience at SJMHS. Membership on this<br />

important workgroup includes staff from most<br />

disciplines, representatives from community<br />

organizations, and oncology patients and<br />

families. Key projects over the past year include:<br />

Implementation of patient support, advocacy and<br />

information symposia during both Cancer Survivors’<br />

Month and Lung Cancer Awareness Month. These<br />

events were jointly sponsored by SJMHS, Wellness<br />

Community, and American Cancer Society.<br />

Patient Satisfaction<br />

A critical component of our quality management<br />

plan is the measurement of how satisfied patients<br />

are with the care we provide. Quarterly surveys are<br />

undertaken for SJMH inpatient areas. One of the<br />

most revealing questions asked relates to whether<br />

the individual patient would recommend the hospital<br />

to family. Results from the most recent survey<br />

conducted during the last quarter of 2009 were<br />

extremely positive for the inpatient oncology unit<br />

at SJMH. Patients rated the hospital in general in the<br />

top decile of the survey respondents. As to whether<br />

oncology patients would recommend the hospital<br />

to family, 83% responded in the affirmative, which,<br />

again, was in the top decile of those responding.<br />

Development of an atmosphere of camaraderie<br />

and sharing in our cancer treatment centers through<br />

activities such as barbeques, musical performances,<br />

and holiday events.<br />

Expansion of the American Cancer Society’s<br />

Resource Center volunteers who align with cancer<br />

program staff to provide patients with information<br />

regarding available resources.<br />

In addition, the Oncology Patient Advocates<br />

Committee appointed a Survivorship Support Team.<br />

The Survivorship Support Team is in the process of<br />

obtaining patient feedback regarding survivorship<br />

issues and is charged with the task of developing<br />

survivorship care plans. A representative from the<br />

Wellness Community is a member of this workgroup<br />

and will provide leadership for this process.<br />

Radiation Oncology has an ongoing patient<br />

satisfaction survey program which includes specifics<br />

to their department (e.g., satisfaction with radiation<br />

schedule, courtesy of staff, etc.). Other components<br />

of the oncology program survey patients and family<br />

members periodically as well as solicit feedback at<br />

all points in their care.<br />

A Patient Speaks<br />

Following is a letter received from a patient written<br />

to Phil Stella, MD, Medical Director of the SJMHS cancer<br />

program. The perspective of this gentlemen is unique,<br />

as he is also a retired physician who was on the SJMHS<br />

staff for more than 35 years. As an internist, he was<br />

particularly interested in and aware of many aspects<br />

of care not evident to most patients entering our doors.<br />

His experience is what we strive for . . . and why the<br />

hundreds of our cancer program physicians and<br />

team members come to work every day.<br />

20 • 2010 Annual Cancer Report


Dear Phil:<br />

Imagine my surprise when what originally was thought to be a rather large<br />

hematoma over my sternum turned out to be a malignancy, hurling me over<br />

to a most uncomfortable position of being a patient -- and a cancer patient<br />

at that! I never thought about “needing” you and your colleagues, being<br />

only desirous of a collegial and social relationship. However, I wanted to<br />

share a few thoughts about my experience, particularly as it relates to what<br />

we all speak so casually about as the “continuum of care.”<br />

First, the diagnostic process was relatively easy. A quick ultrasound and<br />

then an appointment with the surgeon who set me up for a C-T the same<br />

afternoon. Outpatient surgery was readily scheduled to accommodate my<br />

calendar. Then things got interesting. The frozen section was reported to<br />

be a sarcoma.<br />

Over the following week, extraordinary efforts were made on my behalf. The<br />

surgeon arranged for me to see the oncologic surgeon at the University of<br />

Michigan. The pathologists collaborated with their colleagues at U of M to<br />

determine the definitive diagnosis for a somewhat unusual tumor specimen.<br />

To our amazement and relief, a final diagnosis of T-cell lymphoma was<br />

made – a totally curable malignancy which required tried and true<br />

CHOP chemotherapy. I then moved into the medical oncology realm and<br />

appreciated the care and thoughtfulness of Andy Eisenberg, MD, who even<br />

provided me with a thorough literature review of T-cell lymphomas!<br />

Care in the oncology infusion clinic was extraordinary – there’s no other<br />

way to describe it. The expertise and competency of the nursing staff was<br />

apparent. Follow-up required PET scans at 3- and 6-month intervals,<br />

which were scheduled at the time of my visits with Andy.<br />

As I moved through the cancer experience, interacting with multiple<br />

departments (radiology, surgery, pathology, laboratory, medical oncology,<br />

chemotherapy infusion, pharmacy) and cancer center staff, your years<br />

of work to develop a cohesive approach to cancer care was evident –<br />

and I am one grateful patient.<br />

With best regards,<br />

Gerry<br />

2010 Annual Cancer Report • 21


QUALITY INITIATIVES AND OUTCOMES<br />

The SJMHS cancer program is accredited by the<br />

American College of Surgeons’ Commission on<br />

Cancer as a Teaching Hospital Cancer Program.<br />

As such, it is held to the standards of this organization<br />

and must undergo rigorous on-site reviews every<br />

three years.<br />

In 1993, our measurements related to the quality of<br />

care we were providing utilized data from our Tumor<br />

Registry and compared our data with that of other hospital<br />

tumor registries. We were able to review such<br />

things as stage of disease at diagnosis, numbers of patients<br />

enrolling in clinical trials, and morbidity and mortality<br />

data. Over the years we have chosen to participate<br />

in the multiple cancer quality databases available<br />

so as to develop one of the most comprehensive<br />

and far-reaching quality programs in existence today.<br />

These databases include the National Comprehensive<br />

Cancer Network (NCCN) Breast Cancer Database, the<br />

Quality Oncology Physician Initiative (QOPI) sponsored<br />

by the American Society of Clinical Oncology (ASCO),<br />

the Society of Thoracic Surgeons (STS) Database, the<br />

Blue Cross & Blue Shield of Michigan Pathways Project,<br />

and the American College of Surgeons Tumor Registry.<br />

We clearly want to know how our care compares with<br />

that around the country, and “continuous improvement”<br />

is a framework which we embrace.<br />

We are pleased to provide an overview of some of the<br />

quality initiatives that have been accomplished as well<br />

as those that are ongoing.<br />

Oncology & Infusion Collaborative Practice<br />

Team: Review of Chemotherapy Safety<br />

Chemotherapy ordering has been identified as one<br />

of the most complex and potentially dangerous areas<br />

of medicine. Oncology practices and departments<br />

must employ strategies to ensure safety. To this end,<br />

the chemotherapy infusion staff initiated an ongoing<br />

review of “near misses” and chemotherapy errors in<br />

2009, reported via the PEERS (Potential Error/Event<br />

Reporting <strong>System</strong>) process. An Oncology & Infusion<br />

Collaborative Practice Team was established to<br />

oversee this project, and the Hematology/Oncology<br />

Section of the Department of Internal Medicine also<br />

reviewed the data; these two groups worked together<br />

to identify potential for improvement through process<br />

change, staff education and communication. The<br />

table illustrates an outstanding record of chemotherapy<br />

safety at SJMHS.<br />

Although the results are excellent, the Oncology &<br />

Infusion Collaborative Practice Team has developed<br />

standardized chemotherapy order forms as a process<br />

improvement project which will prevent any errors<br />

related to illegible orders.<br />

In addition, the Oncology & Infusion Collaborative<br />

Practice Team reviewed the 2009 Standards for<br />

Excellence in Chemotherapy Administration released<br />

by the American Society of Clinical Oncology and<br />

the Oncology Nursing Society and will be monitoring<br />

their practices to ensure compliance.<br />

2009 Data: Oncology<br />

Error / Near Miss<br />

Number (n)<br />

% of Doses<br />

Number of Errors/Near Misses/Events Reported 33 0.2%<br />

Number of chemotherapy doses given 16,000<br />

• Errors reached patient 17 0.1%<br />

• Unavoidable Events 2 0.0%<br />

• Near Misses 13 0.1%<br />

• Other (non-patient) 1 0.0%<br />

Error/Near Miss Resulted in Treatment Delay 3 0.02%<br />

Error/Near Miss Resulted in Significant Patient Harm 0 0.0%<br />

Extravasation (non-vesicant)/IV dislodgement 2 0.01%<br />

Extravasation (vesicant) 0 0.0%<br />

Avoidable Errors with Computerized Physician Order Entry 12 36.4%<br />

Related to Pump Programming/Pump Double Check 5 15.2%<br />

22 • 2010 Annual Cancer Report


Streamlining <strong>System</strong>s: Chemotherapy<br />

Order Processes<br />

Six Sigma originated as a set of quality management<br />

methods designed to improve manufacturing<br />

processes and eliminate defects, but its application<br />

was subsequently extended to other types of business<br />

processes as well. In Six Sigma, a defect is defined<br />

as any process output that does not meet customer<br />

specifications or that could lead to an output that<br />

does not meet customer specifications. Each Six<br />

Sigma project carried out within an organization<br />

follows a defined sequence of steps and has<br />

quantified targets.<br />

The staff in the Chemotherapy Infusion Clinic<br />

applied the Six Sigma Lean Process to streamline<br />

the chemotherapy order process so that orders were<br />

complete and available to both the pharmacist and<br />

charge nurse for review prior to a patient’s arrival,<br />

thereby ensuring that patients would have their<br />

chemotherapy initiated at their scheduled appointment<br />

time. Assessment of the “defects” or processes<br />

interfering with the desired “output” or goal determined<br />

two critical areas: (1) timing of patient’s laboratory<br />

studies, and (2) processing of chemotherapy orders.<br />

Findings showed that most patients were having their<br />

blood drawn immediately before treatment which<br />

delayed the initiation of chemotherapy and that 10%<br />

of chemotherapy orders required modifications.<br />

New processes were designed which required patients<br />

to have their blood work done at least two hours (and<br />

up to two days) prior to treatment. Chemotherapy<br />

orders are now written 2-5 days before treatment<br />

and submitted to the pharmacy and infusion clinic<br />

by mid-afternoon the day before treatment to allow<br />

the pharmacist and charge nurse to perform a<br />

preliminary review. These changes have resulted<br />

in significant improvements in the efficiency of<br />

chemotherapy schedules and administration.<br />

Streamlining <strong>System</strong>s: Radiation Oncology<br />

The Department of Radiation Oncology utilized the<br />

Six Sigma process to accomplish five goals:<br />

(1) Redesign of the registration process for better<br />

utilization of clerical staff and improved accuracy<br />

of information;<br />

(2) Redesign of the scheduling process to improve<br />

integration of staff and standardization of<br />

patient-centered care;<br />

(3) Redesign of the RN and Clerk roles to better<br />

utilize skills and improve time management of<br />

staff;<br />

(4) Redesign the DosSimulation planning process to<br />

allow more timely and efficient completion of<br />

treatment planning; and<br />

(5) Become a paperless department through<br />

implementation of the electronic medical record.<br />

Although a major undertaking, these quality<br />

improvement efforts were all accomplished over<br />

the course of four months with an added outcome<br />

of going entirely “paperless” when the new SJMHS<br />

Canton Cancer Center opened in November 2009.<br />

Cardiothoracic Surgery: Benchmarking<br />

Through the Society of Thoracic Surgeons<br />

Database<br />

The Society of Thoracic Surgeons began data<br />

collections for cardiac procedures in 1992 and<br />

for thoracic surgery in 2002. SJMHS cardiothoracic<br />

surgeons began contributing to the STS database<br />

in July 2006 when approximately 50 sites were<br />

participating; as of October 2009 there were 142<br />

sites collecting thoracic surgery data and 985 sites<br />

contributing cardiac surgery data.<br />

Utilizing the STS data for 2006-2009 as a benchmark,<br />

the Cardiovascular & Thoracic Surgeons of Ann<br />

Arbor completed a comprehensive study of thoracic<br />

surgery outcomes for that timeframe. They reviewed<br />

data from both open thoracotomies and video-assisted<br />

thoracic surgeries (VATS) with specific interest<br />

in lobectomy and pneumonectomy procedures.<br />

From that they developed/refined length-of-stay<br />

risk models. Patient profiles were consistent with<br />

STS data, and mortality was somewhat better<br />

(1.2% versus 1.6%).<br />

2010 Annual Cancer Report • 23


QUALITY INITIATIVES AND OUTCOMES (con’t)<br />

Medical Oncology: Quality Oncology<br />

Practice Initiative (QOPI)<br />

Ann Arbor Hematology Oncology Associates, the<br />

largest medical oncology private practice at SJMHS,<br />

is participating in the American Society of Clinical<br />

Oncology’s (ASCO) Quality Oncology Practice<br />

Initiative (QOPI). QOPI is one of a series of quality<br />

improvement initiatives underway between Blue<br />

Cross Blue Shield of Michigan, hospitals, and/or<br />

physician groups. QOPI is a physician-led voluntary<br />

program for measuring practice quality whose goal<br />

is to promote excellence in cancer care by assisting<br />

practices in creating a culture of self-examination<br />

and improvement. The oncologists at SJMHS submit<br />

information to ASCO’s national database on<br />

chemotherapy planning, chemotherapy-related<br />

side effects, pain assessment and control, and<br />

specific measures related to the management of<br />

oncology patients and end-of-life care. Blue Cross<br />

Blue Shield of Michigan (BCBSM) is providing funding<br />

to defray data collection costs and to encourage<br />

physician participation. Dr. Stella and Beth<br />

LaVasseur, RN, MSN were instrumental in working<br />

with BCBSM to implement this statewide.<br />

Medical Oncology: Michigan Oncology<br />

Clinical Treatment Pathways Program<br />

The SJMHS medical oncologists are also participating<br />

in the Michigan Oncology Clinical Treatment Pathways<br />

Program, a partnership between Blue Cross Blue<br />

Shield of Michigan, the Michigan oncology community<br />

and P4 <strong>Health</strong>care, an oncology benefit management<br />

company. Participating oncologists utilize oncology<br />

clinical pathways guidelines created by a steering<br />

committee of Michigan oncologists representing the<br />

most up-to-date and effective treatments for cancer<br />

patients. Objectives of the program include:<br />

° Establish evidence-based oncology treatment<br />

pathways for a variety of cancers, specifically<br />

with regard to the use of chemotherapy and<br />

supportive care<br />

° Define optimal quality care and treatment with<br />

the least toxicity while being most cost effective<br />

for the patient, provider, and payer – without<br />

compromising integrity or delivery of treatment<br />

° Decrease variability in treatment regimens between<br />

providers in order to utilize a consistent<br />

treatment regimen based upon a balance between<br />

outcomes, toxicity, and cost<br />

° Improve quality of health care delivery<br />

Initial results have demonstrated less variability<br />

in regimens, reduced misuse of chemotherapy,<br />

better managed toxicity, and more defined<br />

treatment milestones.<br />

Breast Program Quality Initiatives<br />

Nationally accepted guidelines are utilized to evaluate<br />

breast cancer care. A database through the<br />

Blue Cross funded Michigan Breast Oncology Quality<br />

Initiative (MiBOQI) and Quality Oncology Physician<br />

Initiative (QOPI) provides nearly real-time quality<br />

data to assist with benchmarking and ensure compliance<br />

with national guidelines.<br />

Breast program quality metrics for 2009 include:<br />

° The Breast Cancer Multidisciplinary Committee<br />

reviewed all MiBOQI data and chose to investigate<br />

two elements of patient cases that were considered<br />

non-concordant with NCCN Guidelines; these<br />

areas were:<br />

– Stage II, Node Positive Breast Cancer receiving<br />

chemotherapy; 67% of 57 evaluable patients<br />

received chemotherapy;<br />

– Sentinel Node Positive patients receiving axillary<br />

lymph node dissection; 71% of 66 evaluable<br />

patients were concordant.<br />

Each non-concordant patient case was reviewed<br />

and found to have well-documented rationale for<br />

non-compliance.<br />

° Thirteen key Breast Cancer Quality Measures were<br />

reviewed in the most recently diagnosed patients<br />

through the QOPI project at two sampling periods<br />

in 2009. Care measures were consistent with or<br />

demonstrated higher compliance in 12 of the 13<br />

measures. Cases that were non-concordant with<br />

standards were assessed and measures identified<br />

to correct non-compliance where applicable.<br />

24 • 2010 Annual Cancer Report


° The Breast Center undertook a quality improvement<br />

project to decrease the time from request for<br />

screening mammogram appointment to actual<br />

date of screening. In early 2009 the wait time was<br />

14 weeks; this was decreased to same week<br />

scheduling at the time of this report.<br />

° The number of positive biopsies as compared to<br />

number of biopsies completed is continuously<br />

monitored. Our rate of positive biopsies consistently<br />

measures ± 40% which is in keeping with<br />

national standards.<br />

Of key importance is the dedication of SJMH physicians<br />

to ongoing quality improvement. Tari Stull, MD,<br />

member of the Breast Cancer Advisory Committee,<br />

participated in the American Society of Breast<br />

Surgeons’ Mastery of Breast Surgery Pilot Program,<br />

a continuing quality improvement initiative. The<br />

program required a self-reporting process related<br />

to breast surgical procedures for both benign and<br />

malignant disease as a fundamental first step in<br />

improving quality. Ongoing continuing medical<br />

education criteria must be met over the ensuing<br />

five years to continue to meet the requirements of<br />

this program. In addition, Dr. Stull is presently<br />

completing a breast surgery fellowship at Bryn<br />

Mawr Hospital in Bryn Mawr, PA.<br />

Cancer Research Audits (2009-2010)<br />

The Michigan Cancer Research Consortium CCOP<br />

is affiliated with ten National Cancer Institute sponsored<br />

research bases (including the NCI Cancer Trials<br />

Support Unit). Each of these organizations conducts<br />

regularly-scheduled audits of data submitted for<br />

patients on clinical trials. Compliance with the<br />

exacting data requirements of clinical research is a<br />

strength of the MCRC. Over our 17-year history, the<br />

MCRC has established an excellent record for data<br />

quality and timeliness of submissions.<br />

The volume and detail of data submission is truly<br />

phenomenal. Over 120 studies were open for<br />

recruitment in 2009, and more than 1,300 patients<br />

have been enrolled in clinical trials in the past five<br />

years. On-site audits were conducted by the North<br />

Central Cancer Treatment Group (at Mayo Clinic),<br />

the Southwest Oncology Group, and the M.D.<br />

Anderson Cancer Center with excellent results.<br />

American College of Surgeons’ Commission<br />

on Cancer: Outcomes Comparison<br />

The SJMH Cancer Program is accredited by the<br />

American College of Surgeons’ Commission on<br />

Cancer as a Teaching Hospital Cancer Program.<br />

The standards “ensure that cancer services, care,<br />

and patient outcomes are evaluated and improved<br />

so that patients receive care that meets or exceeds<br />

patient expectations and standards distributed by<br />

local, state, regional, and national standard-setting<br />

organizations.” This requires an annual evaluation<br />

of services and care which provides a baseline to<br />

measure quality and an opportunity to correct or<br />

enhance patient outcomes. We continuously review<br />

the outcomes of patients at SJMH, and the following<br />

presents our patient care evaluation for those<br />

individuals with lung cancer including both<br />

non-small cell and small cell lung cancers.<br />

An estimated 222,520 new cases of lung cancer are<br />

expected in the United States for 2010, accounting<br />

for about 15% of cancer diagnoses. The incidence<br />

rate is declining significantly in men, from a high of<br />

102.1 cases per 100,000 in 1984 to 71.3 cases in 2006.<br />

In women, the rate is approaching a plateau after a<br />

long period of increase. Lung cancer is classified<br />

clinically as small cell (14%) or non-small cell (85%)<br />

for purposes of treatment.<br />

According to the National Cancer Institute, lung cancer<br />

is the leading cause of cancer-related mortality in the<br />

United States. An estimated 157,300 deaths, accounting<br />

for about 28% of all cancer deaths, are expected to<br />

occur in 2010. Since 1987, more women have died<br />

each year from lung cancer than from breast cancer.<br />

Since 1990, death rates among men have continued to<br />

decrease while female lung cancer death rates have<br />

been stable since 2003 after continuously increasing for<br />

several decades.<br />

Cigarette smoking is by far the most important risk<br />

factor for lung cancer. Cigar and pipe smoking also<br />

increase risk. Other risk factors include occupational<br />

or environmental exposure to secondhand smoke,<br />

radon, asbestos, certain metals, some organic<br />

chemicals, radiation, air pollution, and a history<br />

of tuberculosis. Genetic susceptibility plays a<br />

contributing role in the development of lung<br />

cancer, especially in those who develop the<br />

disease at a younger age.<br />

2010 Annual Cancer Report • 25


QUALITY INITIATIVES AND OUTCOMES (con’t)<br />

American College of Surgeons’ Commission on Cancer:<br />

Outcomes Comparison (con’t)<br />

A total of 252 new analytic lung cancer cases (267 including non-analytic)<br />

were diagnosed at SJMH in 2009, accounting for 11.5% of all new cancer cases.<br />

Incidence was divided equally between the sexes, with males accounting for<br />

136 and females totaling 131.<br />

Survival Statistics<br />

TABLE 1: Distribution by Age at Diagnosis<br />

Lung Cancer (Analytic Cases)<br />

Age at Diagnosis % & # New Diagnoses # New Diagnoses<br />

SJMH<br />

National Cancer Data<br />

Base (Ncdb)*<br />

0 - 29 0.4% (1) 0.2%<br />

30 - 39 0% (0) 0.8%<br />

40 - 49 3.2% (8) 4.5%<br />

50 - 59 19.1% (48) 18.1%<br />

60 - 69 27.4% (69) 29.4%<br />

70 - 79 33.3% (84) 34.8%<br />

80 - 89 15.9% (40) 11.5%<br />

90+ 0.8% (2) 0.8%<br />

*Clearly demonstrates that the age of patients diagnosed with lung cancer at SJMH is<br />

consistent with national norms.<br />

TABLE 2: Distribution by Stage<br />

Lung Cancer (Analytic Cases)<br />

Stage at Diagnosis SJMH (2009) National Cancer Data<br />

Base (Ncdb)*<br />

Stage I 24.6% (62) 5.4%<br />

Stage II 3.6% (9) 3.3%<br />

Stage III 21.0% (53) 25.5%<br />

Stage IV 38.5% (97) 52.6%<br />

Unknown/Unstaged 12.3% (31) 12.8%<br />

It is of interest to note that almost 25% of SJMH patients are diagnosed with Stage I<br />

local disease as compared with 5.4% of patients nationally. The reasons for this are<br />

not obvious; however, the NCDB data is from earlier years (2000-2007) which might<br />

contribute to the difference as improvements in diagnostic technology have been<br />

made over the years.<br />

*Please note that NCDB Data is from years 2000-2007, which is the most current national<br />

information available.<br />

26 • 2010 Annual Cancer Report


TABLE 3: Initial Therapy<br />

Lung Cancer<br />

Treatment of Modality SJMH (%) National Cancer Data<br />

Base (Ncdb)*<br />

Surgery Only 14.3% (36) 25.6%<br />

Chemotherapy Only 13.1% (33) 7.0%<br />

Radiation Therapy Only 13.9% (35) 10.6%<br />

Radiation + Chemotherapy 17.8% (45) 17.5%<br />

Palliative Treatment* 19.8% (50) Not Specified<br />

Other/Unknown 16.7% (41) 19.4%<br />

Diagnosis Only 13.1% (33) 16.3%<br />

*Palliative treatment incorporates any care provided in an effort to alleviate symptoms. It may<br />

include surgery, radiation, therapy, chemotherapy, and/or other pain management therapy.<br />

Data from the SJMH Tumor Registry compares SJMH lung cancer five-year<br />

survival with the National Cancer Database.<br />

Relative Survival<br />

by Summary at Diagnosis<br />

Stage at Diagnosis<br />

% Five Year Survival % Five Year Survival<br />

SJMH<br />

National Cancer Data<br />

Base (Ncdb)<br />

I 44.9% 46.5%<br />

II 28.0% 26.9%<br />

III 12.8% 11.2%<br />

IV 2.3% 2.4%<br />

Five-year survival information includes patients diagnosed in years 1998 – 2002.<br />

Note that the SJMH data clearly mimics national survival rates.<br />

2010 Annual Cancer Report • 27


APPENDICES<br />

2009 Primary Site: Body <strong>System</strong>, Sex, Class, Status and Best AJCC Stage<br />

Primary Site<br />

ORAL CAVITY & PHARYNX<br />

Sex<br />

Class of Case<br />

Status<br />

Stage Distribution - Analytic Cases Only<br />

Total (%) M F Analy NA Alive Exp Stg 0 Stg I Stg II Stg III Stg IV 88 Unk Blank/Inv<br />

34 (1.4%) 22 12 32 2 29 5 1 5 6 4 11 0 4 1<br />

1 (0.0%) 0 1 0 1 0 1 0 0 0 0 0 0<br />

9 (0.4%) 7 2 8 1 0 0 1 2 5 0 1 0<br />

9 (0.4%) 5 4 9 0 0 2 2 1 1 0 1 0<br />

5 (0.2%) 2 3 3 2 1 2 2 0 0 0 0 0<br />

1 (0.0%) 1 0 1 0 0 0 0 0 1 0 0 0<br />

6 (0.2%) 5 1 6 0 0 0 1 1 3 0 1 0<br />

1 (0.0%) 1 0 1 0 0 0 0 0 1 0 0 0<br />

1 (0.0%) 1 0 0 1 0 0 0 0 0 0 1 0<br />

1 (0.0%) 0 1 1 0 0 0 0 0 0 0 0 1<br />

Lip 1 0<br />

Tongue 9 0<br />

Salivary Glands 7 2<br />

Gum & Other Mouth 5 0<br />

Nasopharynx 1 0<br />

Tonsil 6 0<br />

Oropharynx 1 0<br />

Hypopharynx 1 0<br />

Other Oral Cavity & Pharynx 1 0<br />

DIGESTIVE SYSTEM<br />

349 (14.2%)<br />

187 162 329 20 273 76 3 68 49 68 60 11 70 0<br />

Esophagus 29 (1.2%) 26 3 28 1 22 7 0 5 2 5 7 1 8 0<br />

Stomach 16 (0.7%) 9 7 15 1 9 7 0 5 0 2 3 1 4 0<br />

Small Intestine 10 (0.4%) 6 4 10 0 9 1 0 2 0 1 0 4 3 0<br />

Colon Excluding Rectum 142 (5.8%) 79 63 133 9 130 12 0 33 20 40 20 2 18 0<br />

Cecum<br />

23 11 12 21 2 21 2 0 7 2 6 2 1 3 0<br />

Appendix<br />

6 5 1 4 2 5 1 0 0 0 0 2 0 2 0<br />

Ascending Colon<br />

44 27 17 44 0 42 2 0 10 9 18 4 0 3 0<br />

Hepatic Flexure<br />

5 4 1 4 1 3 2 0 1 0 1 2 0 0 0<br />

Transverse Colon<br />

13 6 7 13 0 12 1 0 2 3 1 3 0 4 0<br />

Splenic Flexure<br />

3 3 0 3 0 3 0 0 3 0 0 0 0 0 0<br />

Descending Colon<br />

7 3 4 7 0 5 2 0 0 1 5 0 0 1 0<br />

Sigmoid Colon<br />

35 17 18 34 1 35 0 0 10 5 9 5 1 4 0<br />

Large Intestine, NOS<br />

6 3 3 3 3 4 2 0 0 0 0 2 0 1 0<br />

Rectum & Rectosigmoid 68 (2.8%) 35 33 63 5 64 4 1 16 10 12 10 3 11 0<br />

Rectosigmoid Junction<br />

7 2 5 7 0 7 0 0 0 3 1 1 0 2 0<br />

Rectum<br />

61 33 28 56 5 57 4 1 16 7 11 9 3 9 0<br />

Anus, Anal Canal & Anorectum 4 (0.2%) 1 3 4 0 4 0 2 0 1 0 0 0 1 0<br />

Liver & Intrahepatic Bile Duct 8 (0.3%) 4 4 8 0 1 7 0 1 1 1 2 0 3 0<br />

Gallbladder 5 (0.2%) 1 4 5 0 2 3 0 0 2 1 0 0 2 0<br />

Other Biliary 9 (0.4%) 4 5 9 0 6 3 0 1 1 0 1 0 6 0<br />

Pancreas 54 (2.2%) 21 33 52 2 23 31 0 4 12 5 17 0 14 0<br />

Retroperitoneum 4 (0.2%) 1 3 2 2 3 1 0 1 0 1 0 0 0 0<br />

RESPIRATORY SYSTEM<br />

283 (11.5%) 151 132 268 15 205 78 3 67 12 56 99 2 29 0<br />

Larynx 16 (0.7%) 15 1 16 0 16 0 3 5 3 3 2 0 0 0<br />

Lung & Bronchus 267 (10.9%) 136 131 252 15 189 78 0 62 9 53 97 2 29 0<br />

BONES & JOINTS<br />

1 (0.0%) 0 1 1 0 1 0 0 1 0 0 0 0 0 0<br />

Bones & Joints 1 (0.0%) 0 1 1 0 1 0 0 1 0 0 0 0 0 0<br />

SOFT TISSUE<br />

6 (0.2%) Sex 5 1 Class 5 of Case 1 Status 5 1 0 0 Stage Distribution 1 - Analytic 1 Cases 1 Only 1 1 0<br />

Soft Primary Tissue Site(including Heart) 6 Total (0.2%) (%) M5 F1 Analy 5 NA 1 Alive 5 Exp 1 Stg 0 0 Stg 0 I Stg 1 II Stg 1 III Stg 1 IV 88 1 Unk 1 Blank/Inv 0<br />

SKIN EXCLUDING BASAL & SQ 216 (8.8%) 110 106 102 114 211 5 47 39 3 0 2 0 11 0<br />

Melanoma -- Skin 209 (8.5%) 108 101 98 111 204 5 47 37 2 0 2 0 10 0<br />

Other Non-Epithelial Skin 7 (0.3%) 2 5 4 3 7 0 0 2 1 0 0 0 1 0<br />

BASAL & SQUAMOUS SKIN<br />

3 (0.1%) 2 1 0 3 3 0 0 0 0 0 0 0 0 0<br />

Basal/Squamous cell carcinoma 3 (0.1%) 2 1 0 3 3 0 0 0 0 0 0 0 0 0<br />

BREAST<br />

523 (21.3%) 12 511 504 19 514 9 118 222 86 13 9 0 56 0<br />

Breast 523 (21.3%) 12 511 504 19 514 9 118 222 86 13 9 0 56 0<br />

FEMALE GENITAL SYSTEM<br />

175 (7.1%) 0 175 147 28 165 10 6 75 7 20 14 4 21 0<br />

Cervix Uteri 38 (1.5%) 0 38 15 23 38 0 0 8 1 2 2 0 2 – continued 0<br />

28 • 2010 Annual Cancer Report<br />

Corpus & Uterus, NOS 85 (3.5%) 0 85 83 2 82 3 0 57 3 8 3 3 9 0<br />

Corpus Uteri<br />

84 0 84 82 2 81 3 0 57 3 8 3 2 9 0<br />

Uterus, NOS<br />

1 0 1 1 0 1 0 0 0 0 0 0 1 0 0


SKIN EXCLUDING BASAL & SQ 216 (8.8%) 110 106 102 114 211 5 47 39 3 0 2 0 11 0<br />

Melanoma -- Skin 209 (8.5%) 108 101 98 111 204 5 47 37 2 0 2 0 10 0<br />

Other Non-Epithelial Skin 7 (0.3%) 2 5 4 3 7 0 0 2 1 0 0 0 1 0<br />

BASAL & SQUAMOUS SKIN<br />

3 (0.1%) 2 1 0 3 3 0 0 0 0 0 0 0 0 0<br />

Basal/Squamous cell carcinoma 3 (0.1%) 2 1 0 3 3 0 0 0 0 0 0 0 0 0<br />

BREAST<br />

523 (21.3%) 12 511 504 19 514 9 118 222 86 13 9 0 56 0<br />

Breast 523 (21.3%) 12 511 504 19 514 9 118 222 86 13 9 0 56 0<br />

ORAL FEMALE CAVITY GENITAL & PHARYNX SYSTEM<br />

34 175 (1.4%) (7.1%) 22 0 12 175 32 147 228<br />

29 165 510<br />

16 575 67 420 11 14 04 421 10<br />

Lip Cervix Uteri 138 (0.0%) (1.5%)<br />

0 138 115 023<br />

038 10<br />

0 18 01 02 02 0 02 0<br />

Tongue Corpus & Uterus, NOS 985 (0.4%) (3.5%) 70 285 983 02<br />

882 13<br />

0 057 13 28 53 03 19 0<br />

Salivary Corpus Glands Uteri<br />

984 (0.4%) 50 484 782 2 981 03<br />

0 257 23 18 13 02 19 0<br />

Gum Uterus, & Other NOSMouth 51 (0.2%) 20 31 51 0 31 20<br />

10 20 20 0 0 01 0 0<br />

Nasopharynx Ovary 137 (0.0%) (1.5%) 10 037 136 01<br />

132 05<br />

0 09 01 09 19 0 08 0<br />

Tonsil Vagina 61 (0.2%) (0.0%) 50 1 61 0 61 0 01 0 10 10 30 0 10 0<br />

Oropharynx Vulva 112 (0.0%) (0.5%) 10 012 110 02<br />

111 01<br />

05 01 02 0 10 0 02 0<br />

Hypopharynx Other Female Genital Organs 12 (0.0%) (0.1%) 10 02 12 0 01 1<br />

0 0 0 01 0 01 10 0<br />

Other MALE Oral GENITAL Cavity SYSTEM & Pharynx 1326 (0.0%) (13.3%) 0326 10 1316 010<br />

1322 04<br />

0 08 0217 027 09 0 054 1<br />

DIGESTIVE Prostate SYSTEM<br />

349 317 (14.2%) (12.9%) 187 317 162 0 329 307 20 10 273 313 76 4 30 68 1 49 215 68 27 60 9 11 0 70 54 01<br />

Esophagus Testis 29 8 (0.3%) (1.2%) 26 8 30 28 8 10<br />

22 8 70<br />

0 57 21 50 70 10 80 0<br />

Stomach Other Male Genital Organs 16 1 (0.0%) (0.7%) 91 70 15 1 10<br />

91 70<br />

0 50 01 20 30 10 40 0<br />

Small URINARY Intestine SYSTEM<br />

10 187 (0.4%) (7.6%) 6133 454 10 174 013<br />

9178 19<br />

079 247 010 16 08 41 323 0<br />

Colon Urinary Excluding Bladder Rectum 142 125 (5.8%) (5.1%) 79 89 63 36 133 116 9 130 119 12 6 075 33 17 20 10 40 0 20 5 20 18 9 0<br />

Kidney Cecum& Renal Pelvis 58 23 (2.4%) 11 41 12 17 21 55 23<br />

21 55 23<br />

03 729 20 6 23 1 313 0<br />

Ureter Appendix<br />

36 (0.1%) 52 1 43 20<br />

53 10<br />

01 01 0 0 20 0 21 0<br />

Other Ascending Urinary Colon Organs 144 (0.0%) 27 1 17 0 44 0 01<br />

42 1 20<br />

0 10 0 90 18 0 40 0 30 0<br />

EYE Hepatic & ORBIT Flexure<br />

25 (0.1%) 41 1 40 12<br />

32 20<br />

0 10 0 10 20 0 0 0<br />

Transverse Colon<br />

Eye & Orbit 2<br />

13<br />

(0.1%)<br />

6 7 13 0 12 1<br />

2 3 1 3 4 1 1 0 2 2 0 0 0 0 0 0 0 0 0<br />

Splenic Flexure<br />

3 3 0 3 0 3 0<br />

3 0 BRAIN & OTHER NERVOUS SY 81 (3.3%) 29 52 77 4 72 9 0 0 0 0 0 77 0 0<br />

Descending Colon<br />

7 3 4 7 0 5 2<br />

1 5 0 1 Brain 33 (1.3%) 19 14 31 2 26 7 0 0 0 0 0 31 0 0<br />

Sigmoid Colon<br />

35 17 18 34 1 35 0<br />

10 5 9 5 1 4 Cranial Nerves Other Nervous S 48 (2.0%)<br />

Large Intestine, NOS<br />

10 38 46 2 46 2 0 0 0 0 0 46 0 0<br />

6 3 3 3 3 4 2 0 1 Rectum ENDOCRINE & Rectosigmoid SYSTEM<br />

68 65 (2.8%) (2.6%)<br />

35 18 33 47 63 61 54<br />

64 60 45<br />

10 16 24 10 5 12 8 10 5 314 11 5 0<br />

Thyroid Rectosigmoid Junction<br />

48<br />

7<br />

(2.0%)<br />

211 537 747 01<br />

744 04<br />

0 024 35 18 15 0 25 0<br />

Other Rectum Endocrine including Thymu 17 61 (0.7%) 33 7 28 10 56 14 53<br />

57 16 41<br />

10 16 0 70 11 0 90 314 90 0<br />

Anus, LYMPHOMA Anal Canal & Anorectum 4101 (0.2%) (4.1%) 159 342 488 013<br />

494 07<br />

20 031 114 010 028 03 12 0<br />

Liver Hodgkin & Intrahepatic Lymphoma Bile Duct 810 (0.3%) (0.4%) 47 43 810 0 110 70<br />

0 14 14 12 20 0 30 0<br />

Gallbladder Hodgkin - Nodal<br />

59 (0.2%) 16 43 59 0 29 30<br />

0 03 24 12 0 0 20 0<br />

Other Hodgkin Biliary - Extranodal<br />

91 (0.4%) 41 50 91 0 61 30<br />

0 1 10 0 10 0 60 0<br />

Pancreas Non-Hodgkin Lymphoma 54 91 (2.2%) (3.7%)<br />

21 52 33 39 52 78 213<br />

23 84 31 7<br />

0 427 12 10 58 17 28 03 14 2 0<br />

Retroperitoneum NHL - Nodal<br />

436 (0.2%) 121 315 233 23<br />

332 14<br />

0 18 04 17 013 01 0 0<br />

NHL - Extranodal<br />

RESPIRATORY SYSTEM<br />

283<br />

55<br />

(11.5%)<br />

31 24 45 10 52 3 0 19 6 1 15 2 2 0<br />

151 132 268 15 205 78 3 67 12 56 99 29 MYELOMA<br />

28 (1.1%) 17 11 27 1 25 3 0 0 0 0 0 27 0 0<br />

Larynx 16 (0.7%) 15 1 16 0 16 0 3 5 3 3 2 0 Myeloma 28 (1.1%) 17 11 27 1 25 3 0 0 0 0 0 27 0 0<br />

Lung & Bronchus 267 (10.9%) 136 131 252 15 189 78<br />

62 9 53 97 2 29 LEUKEMIA<br />

33 (1.3%) 14 19 29 4 26 7 0 0 0 0 0 29 0 0<br />

BONES & JOINTS<br />

1 (0.0%) 0 1 1 0 1 0<br />

1 0 Lymphocytic Leukemia 8 (0.3%) 2 6 5 3 8 0 0 0 0 0 0 5 0 0<br />

Bones & Joints 1 (0.0%) 0 1 1 0 1 1 0 Acute Lymphocytic Leukemia 1 0 1 1 0 1 0 0 0 0 0 0 1 0 0<br />

SOFT TISSUE<br />

6 (0.2%) 5 5 1 5 1<br />

1 1 1 1 Chronic Lymphocytic Leukemia 7 2 5 4 3 7 0 0 0 0 0 0 4 0 0<br />

Soft Tissue (including Heart) 6 (0.2%)<br />

Myeloid & Monocytic Leukemia 23 (0.9%)<br />

5 1 5 1 5 1<br />

1 1 1 1 1 11 12 23 0 16 7 0 0 0 0 0 23 0 0<br />

Acute Myeloid Leukemia<br />

15 7 8 15 0 8 7 0 0 0 0 0 15 0 0<br />

Chronic Myeloid Leukemia<br />

7 3 4 7 0 7 0 0 0 0 0 0 7 0 0<br />

Other Myeloid/Monocytic Leuke 1 1 0 1 0 1 0 0 0 0 0 0 1 0 0<br />

Other Leukemia 2 (0.1%) 1 1 1 1 2 0 0 0 0 0 0 1 0 0<br />

MESOTHELIOMA<br />

4 (0.2%) 3 1 3 1 4 0 0 2 0 1 0 0 0 0<br />

Mesothelioma 4 (0.2%) 3 1 3 1 4 0 0 2 0 1 0 0 0 0<br />

MISCELLANEOUS<br />

39 (1.6%) 19 20 38 1 27 12 0 0 0 0 0 38 0 0<br />

Miscellaneous 39 (1.6%) 19 20 38 1 27 12 0 0 0 0 0 38 0 0<br />

Primary Site<br />

Primary Site<br />

Sex Class of Case Status<br />

Stage Distribution - Analytic Cases Only<br />

Total (%) M F Analy NA<br />

Alive Exp Stg 0 Stg I Stg II Stg III Stg IV 88 Unk Blank/Inv<br />

Sex Class of Case Status<br />

Stage Distribution - Analytic Cases Only<br />

Total (%) M F Analy NA<br />

Alive Exp Stg 0 Stg I Stg II Stg III Stg IV 88 Unk Blank/Inv<br />

Total 2,456 1,108 1,348 2,201 255 2,216 240 257 589 410 214 246 207 276 2<br />

Exclusions: Not Male and Not Female 0<br />

2010 Annual Cancer Report • 29


2009 BEST<br />

GENERAL SUMMARY STAGES<br />

Breast<br />

Analytic Breast Cases<br />

Total Number of Patients<br />

PROSTATE<br />

Analytic Prostate Cases<br />

Total Number of Patients<br />

250<br />

200<br />

150<br />

100<br />

50<br />

0<br />

In-situ Local Regional Distant Unknown<br />

250<br />

200<br />

150<br />

100<br />

The four most commonly occurring<br />

malignancies both nationally and<br />

St. <strong>Joseph</strong> <strong>Mercy</strong> Cancer Center<br />

are breast, prostate, lung and colon.<br />

BREAST CANCER<br />

We have seen a 20 percent increase<br />

in the number of new breast cancer<br />

cases. The distribution of the stage<br />

of disease at diagnosis virtually<br />

replicates that of the past few years<br />

with approximately 67 percent of<br />

our analytic case diagnosed with<br />

in situ or local disease.<br />

50<br />

0<br />

LUNG<br />

50<br />

45<br />

40<br />

Local Regional Distant Unknown<br />

Analytic Lung Cases<br />

Male<br />

Female<br />

PROSTATE CANCER<br />

There was a slight decrease in the<br />

number of our prostate cancer cases<br />

over the past year. Of the 305 analytic<br />

cases, 70% were diagnosed with<br />

local disease.<br />

Total Number of Patients<br />

COLON<br />

Total Number of Patients<br />

35<br />

30<br />

25<br />

20<br />

15<br />

10<br />

5<br />

0<br />

35<br />

30<br />

25<br />

20<br />

15<br />

10<br />

Local Regional Distant Unknown<br />

Analytic Colon Cases<br />

Male<br />

Female<br />

LUNG CANCER<br />

New lung cancer cases remained<br />

virtually the same as last year<br />

(2009 = 251 cases versus 2008 = 264).<br />

This number has remained fairly<br />

consistent over the years.<br />

COLON CANCER<br />

There was a 13% increase in the<br />

number of new colon cancer cases<br />

in 2009, attributable to outreach and<br />

screening activities.<br />

5<br />

0<br />

Local Regional Distant Unknown<br />

30 • 2010 Annual Cancer Report


2009 TUMOR BOARDS / REGISTRY<br />

Tumor Boards<br />

Total Meetings<br />

Central Tumor Board 43<br />

(all cancer types)<br />

Breast Cancer 22<br />

Genitourinary Cancers 8<br />

Head and Neck 20<br />

Tumor Registry<br />

Statistics<br />

Total Records in Database 31,322<br />

Living Patients 15,147<br />

Cases Abstracted 2,454<br />

Data Requests From:<br />

• Physicians 3<br />

• Administration or Research 3<br />

• Other Hospitals/Tumor Registries 75<br />

2010 Annual Cancer Report • 31


APPENDICES<br />

2009-2010 Highlights of Scholarly Activities<br />

Beekman KW, Hussain M. Hormonal<br />

Approaches in Prostate Cancer: Application in<br />

the Contemporary Prostate Cancer Patient.<br />

Urol Oncol. 2008 Jul-Aug;26(4):415-9. Review.<br />

Hines SL, Mincey BA, Sloan JA, Thomas SP,<br />

Chottiner E, Loprinzi CL, Carlson MD, Atherton<br />

PJ, Salim M, Perez EA. Phase III Randomized,<br />

Placebo-Controlled, Double-Blind Trial of<br />

Riedronate for the Prevention of Bone Loss<br />

in Premenopausal Women Undergoing<br />

Chemotherapy for Primary Breast Cancer.<br />

J Clin Oncol. 2009 Mar 1;27(7):1047-53.<br />

Epub 2008 Dec 15.<br />

Byker G, Dinh MT, Gunaratnam NT, Robinson<br />

EA, Shehab TM, Malani, AN. Management<br />

of Clostridium Difficile Infection: Survey of<br />

Practices and Compliance with national<br />

Guidelines among Primary Care Physicians.<br />

Infect Control and Hosp Epidemiol. 2009<br />

Apr;(4):397-9.<br />

Grewal JS, Brar PK, Sahijdak WM, Tworek JA,<br />

Chottiner EG. Bing-Neel syndrome: a case report<br />

and systematic Review of Clinical Manifestations,<br />

diagnosis and treatment Options. Clin<br />

Lymphoma Myeloma. 2009 Dec;9(6):462-6.<br />

Grewal JS, Smith LB, Winegarden JD 3 rd , Krauss<br />

JC, Tworek JA, Schnitzer B. Highly Aggressive<br />

ALK-positive Anaplastic Large Cell Lymphoma<br />

with a Leukemic Phase and Multi-organ Involvement:<br />

A Report of Three Cases and a Review of<br />

the Literature. Ann Hematol. 2007 Jul;86(7)499-<br />

508. Epub 2007 Mar 30. Review.<br />

Jatoi A, Schild SE, Foster N, Henning GT,<br />

Dornfeld KJ, Flynn PJ, Fitch TR, Dakhil SR,<br />

Rowland KM, Stella PJ, Soori GS, Adjei AA. A<br />

Phase II Study of Cetuximab and Radiation in<br />

Elderly and/or Poor Performance Status<br />

Patients with Locally Advanced Non-Small<br />

Lung Cancer (N0422). Ann Oncol. 2010 Jun 21.<br />

Loprinzi CL, Dueck AC, Khoyratty BS, Barton DL,<br />

Jafar S, Rowland KM Jr, Atherton PJ, Marsa GW,<br />

Knutson WH, Bearden JD 3rd, Kottschade L,<br />

Fitch TR. A Phase III Randomized, double-blind,<br />

placebo-controlled trial of gabapentin in the<br />

management of hot flashes in men (N00CB).<br />

Ann Oncol. 2009 Mar;20(3):542-9. Epub Jan 6.<br />

Greil S, Robinson EA, Singal B, Kleer E. Efficacy<br />

over time of LHRH Analogs in the Treatment<br />

of Pca—a Prospective Analysis Using Serum<br />

Testosterone to Determine Doing Intervals.<br />

Urology. 2009 Mar;73(3):631-4. Epub 2008<br />

Dec 24.<br />

Hayes MJ, Carey JL, Krauss JC, Hedstrom DL,<br />

Gulbranson RL, Keren DF. Low IgE Monoclonal<br />

Gammopathy Level in Serum Highlights 20-yr<br />

Survival in a Case of IgE Multiple Myeloma.<br />

Eur J Haematol. 2007 Apr;78(4):353-7.<br />

Pulaski HL, Spahlinger G, Silva IA, McLean K,<br />

Kueck AS, Reynolds RK, Coukos G. Conejo-<br />

Garcia JR, Buckanovich RJ. Identifying<br />

Alemtuzumab as an Anti-Myeloid Cell<br />

Antiangiogenic Therapy for the Treatment of<br />

Ovarian Cancer. J Transl Med. 2009 Jun<br />

19;7:49.<br />

Kueck A, Opipari AW Jr, Griffith KA, Tan L,<br />

Choi M, Huang J, Wahl H, Liu JR. Resveratrol<br />

Inhibits Glucose Metabolism in Human<br />

Ovarian Cancer Cells. Gynecol Oncol. 2007<br />

Dec;107(3):450-7. Epub 2007 Sep 10.<br />

Uhm JH, Ballman KV, WU W, Giannini C, Krauss<br />

JC, Buckner, JC, James CD, Scheithauer BW,<br />

Behrens RJ, Flynn PJ, Schaefer PL, Dakhill SR,<br />

Jaeckle KA. Phase II Evaluation of Gefitinib<br />

in Patients with Newly Diagnosed Grade 4<br />

Astrocytoma: Mayo/ North Central Cancer<br />

Treatment Group Study N0074. Int J Radiat<br />

Oncol Biol Phys. 2010 May 24.<br />

32 • 2010 Annual Cancer Report


Barton DL, LaVasseur BI, Sloan JA, Stawis AN,<br />

Flynn KA, Dyar M, Johnson DB, Atherton PJ,<br />

Diekmann B, Loprinzi CL. Phase III, Placebo-<br />

Controlled Trial of Three Doses of Citalopram<br />

for the Treatment of Hot Flashes: NCCTG Trial<br />

N05C9. J Clin Oncol. 2010 Jul 10;28(20):3278-83.<br />

Epub 2010 May 24<br />

Smith DC, Mackler NJ, Dunn RL, Hussain M,<br />

Wood D, Lee CT, Sanda M, Vaishampayan U,<br />

Petrylak DP, Quinn DI, Beekman K, Montie JE.<br />

Phase II Trial of Paclitaxel, Carboplatin and<br />

Gemcitabine in Patients with Locally<br />

Advanced Carcinoma of the Bladder.<br />

J Urol. 2008 Dec;180(6):2384-8; discussion 2388.<br />

Epub 2008 Oct 18.<br />

Chen AM, Lee NY, Yang CC, Liu T, Narayan S,<br />

Vijayakumar S, Purdy JA. Comparison of<br />

Intensity-Modulated Radiotherapy Using<br />

Helical Tomotherapy and Segmental Multileaf<br />

Collimator-based Techniques for<br />

Nasopharyngeal Carcinoma: Dosimetric<br />

Analysis Incorporating Quality Assurance<br />

Guidelines from RTOG 0225. Technol Cancer<br />

Res Treat. 2010 Jun;9(3):291-8.<br />

Moraska AR, Atherton PJ, Szydlo DW, Barton DL,<br />

Stella PJ, Rowland KM Jr, Schaefer PL, Krook J,<br />

Bearden JD, Loprinzi CL. Gabapentin for the<br />

Management of Hot Flashes in Prostate Cancer<br />

Survivors: A Longitudinal Continuation Study-<br />

NCCTG Trial N00CB. J Support Oncol. 2010<br />

May-Jun;8(3):128-32.<br />

Haura EB, Ricart AD, Larson TG, Stella PJ,<br />

Bazhenova L, Miller VA, Cohen RB, Eisenberg<br />

PD, Selaru P, Wilner KD, Gadgeel SM. A Phase II<br />

Study of PD-0325901, An Oral MEK Inhibitor, In<br />

Previously Treated Patients with Advanced<br />

Non-Small Cell Lung Cancer. Clin Cancer Res.<br />

2010 Apr 15;16(8):2450-7. Epub 2010 Mar 23.<br />

Jatoi A, Foster NR, Egner JR, Burch PA, Stella, PJ,<br />

Rubin J, Dakhil SR, Sargent DJ, Murphy BR,<br />

Alberts SR. Older Versus Younger Patients with<br />

Metastatic Adenocarcinoma of the Esophagus,<br />

Gastroesophageal Junction, and Stomach:<br />

A Pooled Analysis of Eight consecutive North<br />

Central Treatment Group (NCCTG) Trials.<br />

Int J Oncol. 2010 Mar;36(3):601-6.<br />

Adjei AA, Mandrekar SJ, Dy GK, Molina JR,<br />

Gandara DR, Allen Ziegler KL, Stella PJ,<br />

Rowland KM Jr, Schild SE, Zinner RG. Phase II<br />

Trial of Pemetrexed Plus Bevacizumab for<br />

Second-Line Therapy of Patients with Advanced<br />

Non-Small-Cell Lung Cancer: NCCTG and<br />

SWOG Study N0426. J Clin Oncol. 2010 Feb<br />

1;28(4):614-9. Epub 2009 Oct. 19.<br />

Tan WW, Hillman DW, Salim M, Northfelt DW,<br />

Anderson DM, Stella PJ, Niedringhaus R,<br />

Bernath AM, Gamini SS, Palmieri F, Perez EA.<br />

N0332 Phase II Trial of Weekly Irinotecan<br />

Hydrochloride and Docetaxel in Refractory<br />

Metastatic Breast Cancer: A North Central<br />

Cancer Treatment Group (NCCTG) Trial. Ann<br />

Oncol. 2010 Mar;21(3):493-7. Epub 2009 Jul 22 .<br />

Socinski MA, Saleh MN, Trent DF, Dobbs TW,<br />

Zehngebot LM, Levine MA, Bordoni R, Stella PJ.<br />

A Randomized Phase II Trial of Two Dose<br />

Schedules of Carboplatin/Paclitaxel/<br />

Cetuximab in Stage IIIB/IV Non-Small-Cell Lung<br />

Cancer (NSCLC). Ann Oncol. 2009 Jun;20(6):1068-<br />

73. Epub 2009 Feb 2.<br />

Wasco MJ, Daignault S, Bradley D, Shah RB.<br />

Nested variant of urothelial carcinoma: a<br />

clinicopathologic and immunohistochemical<br />

study of 30 pure and mixed cases. Hum Pathol.<br />

2010 Feb;41(2):163-71. Epub 2009 Oct 1.<br />

Weizer AZ, Wasco MJ, Wang R, Daignault S,<br />

Lee CT, Shah RB. Multiple adverse histological<br />

features increase the odds of under staging T1<br />

bladder cancer. J Urol. 2009 Jul;182(1):59-65;<br />

discussion 65. Epub 2009 May 17. Erratum in:<br />

J Urol. 2009 Sep;182(3):1237.<br />

2010 Annual Cancer Report • 33


APPENDICES<br />

2009-2010 Publications & Resident Awards SJMHS Dermatology<br />

JAAD Publications<br />

° Jason Mazzurco: Phaeohyphomycosis Caused by<br />

Phaeoacremonium Species in a Patient Taking<br />

Infliximab (Accepted for publication 4/2010)<br />

° Amy Basile: Disseminated Strongyloides stercoralis:<br />

Hyperinfection during medical immunosuppression.<br />

(Accepted for publication 2/22/2010)<br />

International Journal of Dermatology<br />

Publications<br />

° Jason Mazzurco: Localized Mycosis Fungoides of the<br />

Bilateral Thumbs and Nail Units Treated with Orthovoltage<br />

Radiation Accepted for publication (3/10)<br />

° Jason Mazzurco: Eruptive Disseminated Spitz Nevi in<br />

a 26-Year-Old African American Woman (6/10)<br />

AOCD Publications<br />

° Amy Basile: Plexiform Firohistiocytoma in a 13-yearold<br />

female: Case report and brief review. April 2010,<br />

Volume 16, Number 1.<br />

Journal of Drugs in Dermatology Publications<br />

° Brooke Bair: Lenalidomide manuscript (6/10)<br />

Other Publications<br />

° Jeni Stead: Palmoplantar erythrodysesthesia<br />

syndrome induced by capecitabine (Xeloda(r)) -<br />

Dermatology Clinics (6/10)<br />

Michigan Dermatology Society<br />

° 5 Honorable mentions: D. Cleaver, J. Mazzurco, J.<br />

Stead, A. Basile, C. Messana<br />

° Winter MDS Meeting: Residency program hosted the<br />

meeting at SJMHS in February 2010 comprised of 36<br />

patient presentations of interesting & difficult<br />

dermatological cases.<br />

•Resident PowerPoint Presentations:<br />

6/10 residents presented interesting cases<br />

Resident PowerPoint Presentations<br />

° AOCD New Orleans, Nov. 2009: 7/10 residents<br />

presented 15-minute PowerPoint presentations<br />

° Cosmetic Surgery Forum, Las Vegas Dec. 2009:<br />

David Cleaver Presented a surgical case<br />

° AAD Miami FL, March 2010: 5 Residents presented<br />

at Gross & Microscopic Symposium<br />

• Brooke Bair, Nichole Edwards, Emily Fibeger,<br />

Jennifer Stead, Christopher Messana<br />

° Dominican Republic: Interesting cases from Michigan<br />

Presented by J.Mazzurco, D.Cleaver, B.Bair<br />

° AOCD midyear meeting, Sedona, Az, April 2010:<br />

Two residents presented<br />

Resident Awards<br />

° Jason Mazzurco: Australia Surgical Paper Competition<br />

Winner, Nov. 2009<br />

° David Cleaver: ASDS Surgical Scholarship Recipient<br />

Dec. 2009<br />

° Brooke Bair: Caribbean Dermatology Recipient<br />

Jan. 2010 - Triax Resident Research Award<br />

° ARTE Scholarship to attend Orlando Dermatology<br />

meeting, Jan. 2010: Jason, David, Brooke<br />

° Brooke Bair: ASLM Resident Research competition<br />

for oral presentation<br />

° Brooke Bair: 2008-2009 Michigan Dermatological<br />

Society Residents’ Research Paper Award<br />

Ongoing Research<br />

° Cutera laser research: Four active abstracts in<br />

development (1st/2nd year residents)<br />

° Teledermatology Study<br />

Resident Poster Presentations<br />

° ASDS Meeting Phoenix, Az, Sept. 2009: David Cleaver<br />

presented surgical poster<br />

° ASDP Meeting Chicago, IL, Oct. 2009: 3 Residents<br />

presented pathology posters<br />

• Brooke Bair, Sarah Maggio, Jennifer Stead<br />

° MDS Winter Meeting, SJMHS February 2010:<br />

5 Residents presented posters<br />

° SJMHS Resident research poster session, April, 2010:<br />

9/10 Residents presented posters<br />

° ASDS Meeting Chicago 2010: Amy Basil presenting<br />

a poster on Mohs surgery for Merkel Cell CA<br />

34 • 2010 Annual Cancer Report


St. <strong>Joseph</strong> <strong>Mercy</strong><br />

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st. joseph mercy<br />

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1600 S. Canton Center Road<br />

Canton, MI 48188<br />

St. <strong>Joseph</strong> <strong>Mercy</strong> Cancer Program<br />

888-474-HOPE / 888-474-4673<br />

stjoeshealth.org

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