Technetium radiopharmaceuticals

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In-Vitro Method •Blood is drawn from patient and RBC’s are separated by centrifugation and washing •The cells are then incubated with appropriate amount of Sn and then washed to remove excess tin •The appropriate amount of pertechnetate is then added and allowed to incubate •Labeling efficiency is >97%
In-Vivo Method •A kit of Sn-PYP is reconstituted with isotonic saline •The proper dose (10-20 microgram/kg) is injected into patient •Wait 20 to 30 minutes and inject 20-30 mCi of pertechnetate to tag the RBC’s immediately •Labeling efficiency is 80-90%
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Page 3 and 4: What Are Cold Kits? o Non-radioacti
Page 5: • The chelating agent usually don
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Page 11 and 12: preparation
Page 14 and 15: Preparation
Page 19: Preparation
Page 29 and 30: Tc-99m Labeled WBCs •Used for loc
Page 31 and 32: Tc-99m WBC Labeling Procedure • C
Page 39: Three Ways to Prepare Tc-99m RBCs
Page 55 and 56: Radioiodine( 131 I, 123 I, 125 I)
Page 57 and 58: Protein labeling • Monochloride i
Page 59 and 60: • 125 I-Sodium Iothalamate
Page 61 and 62: Indium •ProductionP d • 111 Cd
Page 63: Other radionuclides • Thallium 20

Technetium radiopharmaceuticals

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