View the VLT profile - Agel

PRODUCT PROFILE

Contents
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Introduction
Marketing Summary
Research Monograph
Scientific Summary & Current Use
Product Label
Approved Claims
Safety Cautions & Assessment
Age Guidelines for Use/Shelf Life
Glossary
References & Additional Resources

PRODUCT PROFILES
who we are...
Agel Vision
The Global Leader in Suspension Gel Technology
based Nutritional Products
Agel Purpose
AGEL and our Product Profiles in Innovation,
Research, Quality and Safety provide the necessary
components for a confident, well-informed
community of empowered team members
through:
• Safe and beneficial products
• Clear and organized information
• Compliance to well-defined systems
VLT
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Marketing Summary
The energy you need.
High-Energy
This new high-energy Agel product combines caffeine, vitamins, and selected herbs to
create the ultimate high-energy gel for active people. Agel VLT is an energy gel superior in
effect to energy drinks. It provides the quick energy you need without the sudden crash*.
VLT Benefits
• Provides a sustained burst of energy in a suspension gel dosage form
• Supports the synthesis of ATP (natural fuel for the muscles)*
• Vegetarian and non-gluten ingredients
• Low glycemic ingredients
• Excellent source of selected B vitamin ingredients and high potency anti-oxidant
Vitamin C
• Contains Acetyl L-Carnitine (ALC) that has been shown to reduce both physical and
mental fatigue associated with aging. ALC is a precursor to the important brain neurotransmitter
acetylcholine, which contributes to the support of cognitive function and
memory**
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**These statements have not been evaluated by the Food and Drug Administration. This product is not intended to
diagnose, treat, cure or prevent any disease.

Research
MONOGRAPH
Product History
& Traditional Use
VLT is a new product introduction to Agel in 2011.
It’s formulation represents emerging energy research
coupled with traditional research on nutritional
ingredients and caffeine. Naturally occurring caffeine
is an ingredient in VLT.
Caffeine containing plants have played an important
role in the civilization of mankind. The cultural and
historical use on caffeine containing plants dates
back thousands of years. According to Chinese
legend, Tea (Camellia sinensis) was discovered
when leaves of tea fell into boiling water to create a
refreshing and pleasant beverage. The Tea beverage
is said to be the second only to water as a consumed
beverage. Coffee played a role in cultures and
traditions of Africa, Middle East before gaining
acceptance in Europe. Chocolate use dates back
to ancient civilizations in South America and it was
esteemed as a form of valued currency. Guarana
has been used by native South American peoples
(including the Guaranis) for centuries and was
introduced to European settlers as far back as the
16th century. Caffeine containing beverages have
played a role in social settings as an element of the
cultural fabric of society and human interactions.
Examples of caffeine containing plants are listed
below:
name scientific name source current use*
Guarana Paullinia cupana South America Energy, Social
Tea Camellia sinensis Asia Social Settings,
Mild Energy
Coffee Coffea arabica Africa, Middle East Energizing Stimulant
Chocolate Theobroma cacao South America Currency, Energy
Beverage, Anti-Fatigue
Kola Nuts Cola nitida Western Africa Restorative Vitality
Yerba Mate Ilex paraguariensis South America Social Beverage
Yaupon Ilex vomitoria North America Social Beverage
and Purification
Description Agel VLT is a blend of naturally occurring caffeine, amino acids, and nutrients
formulated in a suspension gel dosage form to deliver the energy nutrients you need.**Naturally occurring
caffeine is an ingredient in VLT. Each VLT packet contains about 165mg of caffeine or about as much of 2-3
cups of generic brewed coffee.
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Product History Continued
The isolation and chemical characterization of
caffeine dates back to early 19th century by German,
French, and Swedish chemists. The chemical
structure of caffeine was identified near the end of
the 19th century by Hermann Emil Fischer. He was
awarded the Nobel Prize in 1902 in part for his work
on the synthesis and characterization of caffeine.
The naturally occurring chemical caffeine is one of
the few substances that have been used as a food
(natural flavoring as a bitter substance), dietary
supplement, and as a drug (over the counter mild
stimulant). The amount of caffeine and its labeling
determine its use. In other words, the product
dosage and amount of caffeine are two factors that
determine whether caffeine has food, supplement,
or drug applications. It is important to use caffeine
responsibly. Label directions for caffeine containing
products should be followed as misuse of this
ingredient can lead to potential adverse reactions.
vlt ingredient phytonutrient traditional use* current use**
Caffeine Caffeine Food Flavor, Bitter,
Energy
Dietary Supplement, Food,
Pharmaceutical
Guarana Extract
Caffeine,
Theobromine,
Theophylline
Mood, Memory,
Alertness
Flavor, Energy,
Pharmaceutical
Glycine Glycine Nutrition Protein, ATP,
Glutathione Synthesis,
Antioxidant
Acetyl L-Carnitine Acetyl L-Carnitine Nutrition ATP Production
Glucuronolactone Glucuronolactone Nutrition, Detoxification Dietary Supplement
Vitamin C Vitamin C Scurvy Anti-oxidant Metabolic
Support
B Vitamins
Vitamin B3 (Niacin),
B6 (Pyridoxine), B12
(Cyanocobalamin)
Nutrients
Endurance
Check PRO
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*Traditional use claims have not been verified by modern scientific research.
**These statements have not been evaluated by the Food and Drug Administration. This product is not intended to
diagnose, treat, cure or prevent any disease.

Scientific Summary
& CURRENT USE
Caffeine is used as a dietary supplement
ingredient in VLT. There are about 165 mg of
caffeine per VLT dosage that provide energy and
nutritional support. Excessive dosages of VLT
combined with caffeinated beverages or other
sources of caffeine should be avoided. The VLT
formulation is designed to incorporate a balanced
amount of caffeine and other nutrients to provide
short and longer term sustained energy. Energetic
effects may last 3-4 hours and complement the
longer term energy impacts of VLT nutrients.
Preliminary studies have demonstrated that subjects
can cycle up to 29% longer during high-intensity
circuits after taking caffeine in VLT.
Guarana Extract A source of xanthine
alkaloids including caffeine, theobromine and
theophylline. Guarana contains polyphenols,
and catechins and epicatechins (Green Tea type
nutrients). It is used as a popular carbonated soft
drink and as a dietary supplement ingredient. It
is used in VLT to complement the other nutritional
ingredients with a balanced nutritional and flavor
profile.
Glycine acts to support the energy metabolism
in the body. It inhibits and neutralizes free radicals
that may form during extended exercise. It is key
to the synthesis of ATP, glucose and glycogen that
provide energy to our bodies.
Acetyl L-Carnitine is the acetylated form
of L-carnitine. It increases ATP production on a
cellular level in our mitochondria and plays a role
in the body’s energy metabolism. It provides an
impact to the cardiac and neuroprotective systems.
Glucuronolactone is a precursor for
Vitamin C synthesis and both of these substances
have been demonstrated to play a role in structural
and connective tissues in the body.
B Vitamins & Vitamin C Each
VLT dosage provides Niacin (B3 at 70% Daily
Value), pyridoxine (B6 at 70% Daily Value) and
cyanocobalamin (B12 at 23% Daily Value). Each are
essential nutrients that have been associated with
energy and wellness. Vitamin C at 40 mg or 67%
DV per dosage is a recognized anti-oxidant and
supports neutralization of free radicals. Vitamin C is
recognized in supporting the structural elements of
skin, tissues, and bone. Deficiency of Vitamin C has
been identified as an element in scurvy (disease of
the skin and mucous membranes). Each packet
and dosage provides a rich source of B vitamins
and Vitamin C.
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Product Label
Take one Agel VLT packet a day
Agel VLT has been specifically
formulated to provide a sustained
energy boost that supports
concentration, focus and endurance.
Allowing you to perform at your
best. With B vitamins that are
essential for energy, endurance and
stamina and low in sugar, VLT gives
you the energy you need now.*
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Approved Claims
Key Ingredients
Caffeine, Glycine, N-Acetyl-L-Carnitine, Glucoronolactone, B-Vitamins, B3 (niacin), B6 (pyridoxine),
B12 (cyanocobalamin), Ascorbic acid (Vitamin C)
approved
Rich, excellent, or high source of high potency
anti-oxidant (vitamin C).
not approved
VLT provides instant energy, all day long.
Increases energy to support concentration,
focus, and endurance
Prevents sickness and disease.
The sustained energy boost helps you perform
your best. VLT is low in sugar which helps avoid
the crash associated with many energy supplements
AGEL VLT is a good source of vitamins and minerals.
Take one packet of VLT to boost energy and
alertness
A safe and effective stimulant
Notes
1
Not to be used at bed time or prior to retiring
for sleep.
2
This product contains about 165mg of
caffeine (about as much as 2-3 cups of
generic brewed coffee. Do not take this
product if you are pregnant, nursing, or
sensitive to caffeine. Not for children.
Consult your doctor before taking any
dietary supplement.
3
VLT is a Vitamin B infused formulation of
amino acids and natural caffeine to provide a
daily boost of energy.
4
The VLT packet is 1.0 oz.(29.5 g). The
existing typical Agel packet gels have a
content of 0.75oz (21 g). The Omega 3
packet content is 0.35 oz.(10 g).
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Safety Cautions
& ASSESSMENT
The safety issues with VLT are primarily associated with the caffeine content.
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• Warning This product contains
about 165 mg of caffeine (about as
much as 2-3 cups of generic brewed
coffee). Do not take this product if you
are sensitive to caffeine.
• Pregnant or lactating women (or those
planning pregnancy) should consult
their physician prior to using this
product.
• If you are planning a surgery, disclose
use of Agel VLT and all other dietary
supplements to your physician.
• A dosage of one Agel VLT packet
a day can be safely used by most
people, unless there is a reason not to
use this product.
• VLT is intended for adult use. Not for
children. It is not intended for use in
individuals under 18 years of age.
• Dosages of more than 250-300 mg
of caffeine (two VLT packets a day)
have been associated with sleep
disturbance and heart rate impact.
• Caffeine has GRAS (Generally
Regarded as Safe) status in the US.
• Do not take VLT if you are planning to
rest or retire to sleep.
• Caffeine is an FDA approved
ingredient in many over-the-counter
drug products.
• No observable adverse effect level of
glucuronolactone at 1000mg/body
kg/day. VLT has less than 100mg
glucuronolactone per dosage.
• LD50 of glycine is 7930 mg/kg in rats
(oral). VLT has 250 mg of glycine per
dosage.
Key Ingredients
Caffeine, Vitamin C, Vitamin B3, Vitamin B6, Vitamin
B12, Glycine, Guarana ext, Acetyl L-Carnitine,
Glucuronolactone

Age Guidelines
FOR USE
age group class approximate age use recommendation
Newborn Birth to one month of age Not recommended for use
Infant One month to 2 years Not recommended for use
Child 2 years to 12 years Not recommended for use
Adolescent 12 years to 17 years Not recommended for use
Adult 17 years and older 1 packet daily
Agel Guidelines
1
2
Individual conditions should be considered when considering use, including weight,
sex, pre-existing medical conditions, sensitivity or allergic reactions to ingredients,
use of prescription medication or other drugs.
Individuals should begin Agel product use with one Agel product at the lowest
dosage and increase dosage and add other complementary Agel products as
needed.
Product Shelf Life
Agel VLT has a shelf life of 18 months when stored under
ambient conditions
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Glossary
Acetyl L-Carnitine (ALC) The
acetyl form of L-Carnitine useful for fatty acid
metabolism.
Adenosine Tri Phosphate (ATP)
It transfers chemical energy within cells for
metabolic reactions. It has been called the
“currency of cellular energy”.
L-Carnitine Chemical compound that is
required for utilization (transport and breakdown)
of fats. Nitrogen containing product obtained
from biosynthesis of lysine and methionine.
Glucuronolactone Chemical
compound that is a structural component of
connective tissue.
Caffeine Naturally occurring phytochemical
in selected plants. A xanthine alkaloid.
Glucose Naturally occurring sugar.
Glutathinone Tri-peptide chemical
compound that acts as an antioxidant to protect
cells from free radical oxidation or damage.
Glycogen A polysaccharide that is the chief
storage carbohydrate in animals.
Glycine An amino acid. Key for the synthesis
of proteins, ATP, glutathione, glucose, glycogen
and more.
Xanthine Alkaloids Nitrogen containing
chemical compounds based on the purine
structure, including caffeine, theobromine, and
theophylline. Considered to be phytonutrients
that act as mild stimulants and bronchodilators.
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References
• Astorino TA, Roberson DW (January 2010).
“Efficacy of acute caffeine ingestion for shortterm
high-intensity exercise performance: a
systematic review”. J Strength Cond Res 24
(1): 257–65.
• Baker EM, Bierman EL, Plough IC.
1960. Effect of D-glucuronic acid and
D-glucuronolactone on ascorbic acid
levels in blood and urine of man and dog”.
American Journal of Clinical Nutrition. 8:369-73.
• Cao Y, Wang YX, Liu CJ, Wang LX, Han
ZW, Wang CB (2009). “Comparison of
pharmacokinetics of L-carnitine, acetyl-Lcarnitine
and propionyl-L-carnitine after single
oral administration of L-carnitine in healthy
volunteers”. Clinical and Investigative Medicine
32 (1): E13–9.
• “Safety (MSDS) data for glycine” ( “http://
physchem.ox.ac.uk/MSDS/GL/glycine.html”
http://physchem.ox.ac.uk/MSDS/GL/glycine.
html.) Weinberg BA, Bealer BK (2001).
• Jellin JM, Gregory PJ, et al. Pharmacist’s
Letter/Prescriber’s Letter Natural Medicines
Comprehensive Database. 11th Edition.
Stockton, CA: Therapeutic Research Facility.
2009
• Peters, Josef M. (1967). “Factors Affecting
Caffeine Toxicity: A Review of the Literature”.
The Journal of Clinical Pharmacology and
the Journal of New Drugs (7): 131–141.
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• Nehlig, A; Daval, JL; Debry, G (1992).
“Caffeine and the central nervous system:
mechanisms of action, biochemical,
metabolic and psychostimulant effects”. Brain
Research Reviews 17 (2): 139–70.
• Nehlig A (2010). “Is caffeine a cognitive
enhancer?”. J. Alzheimers Dis. 20 Suppl 1:
S85–94.
• Weinberg BA, Bealer BK (2001). The World of
Caffeine. Routledge.
• If you would like to review these publications
in more detail we suggest you use PubMed,
the information portal provided by the US
National Library of Medicine and the National
Institutes of Health. PubMed is a service
of the U.S. National Library of Medicine
that includes over 17 million citations from
MEDLINE and other life science journals for
biomedical articles back to the 1950s.
Additional Resources
Agel Product Profiles and Organization
Agel Suspension Gel Technology FAQ
US Regulatory Requirements
European (EU) Regulatory Requirements
Agel Primary Use for All Agel Products
Responsible Use of Agel Nutritional Supplements
Agel Compliant Claim Guidelines for All Products
Agel Product Shelf Life (All Products)
Agel Quality (QA/QC 2011)
Product Profiles Listing of Item Numbers and Release
Dates
Product Certification (Halal and Kosher Lists)
Agel Glossary (All Products)
Agel Product Shelf Life
Agel Quality (QA/QA 2011)
• To find a reference on PubMed, copy the
reference for the article you want to read
from the Agel Bibliography page and paste it
in the “Search PubMed for” entry box on the
following web page:
http://www.pubmed.gov
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