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Order now! - Pharmacist eLink

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<strong>Order</strong> <strong>now</strong>!<br />

Now available<br />

in 2 new strengths<br />

New 50-mg and 400-mg tablets<br />

• 50 mg for simpler dosing during initiation<br />

• 400 mg for an easier way to achieve higher doses †<br />

Strength<br />

Size<br />

Unit Dimensions<br />

NDC Height Width Depth<br />

SEROQUEL<br />

50 mg<br />

100 count 0310-0278-10 2.84" 1.62" 1.62"<br />

SEROQUEL<br />

50 mg<br />

100-count<br />

unit dose<br />

0310-0278-39 0.2" 4.5"<br />

2.8"<br />

SEROQUEL<br />

50 mg<br />

1000 count<br />

0310-0278-34<br />

4.26"<br />

2.03"<br />

2.03"<br />

50 mg<br />

1000 count<br />

50 mg<br />

100 count<br />

400 mg<br />

100 count<br />

SEROQUEL<br />

400 mg<br />

SEROQUEL<br />

400 mg<br />

100 count<br />

100-count<br />

unit dose<br />

0310-0279-10<br />

4.26"<br />

2.03"<br />

2.03"<br />

0310-0279-39 0.3" 4.5" 2.8"<br />

<strong>Order</strong> Now! <strong>Order</strong>s should be placed through your<br />

wholesaler. Please contact your wholesaler immediately<br />

for product price and available quantities.<br />

AstraZeneca has dedicated approximately 2500<br />

Professional Sales Specialists to promote the new<br />

50-mg and 400-mg tablets to various medical<br />

specialists nationwide.<br />

*All atypical prescriptions: Total prescriptions. Jan. 05-Dec. 05. New prescriptions.<br />

Sept. 04-Dec. 05. IMS Health. National Prescription Audit.<br />

†<br />

The safety of doses above 800 mg/day has not been evaluated in clinical trials.<br />

In the elderly and in patients with hepatic impairment, consideration should be<br />

given to a lower starting dose, a slower rate of dose titration, careful monitoring<br />

during the initial dosing period, and a lower target dose.<br />

For full Prescribing Information, please click here<br />

http://www.astrazeneca-us.com/pi/seroquel.pdf<br />

25 mg, 50 mg, 100 mg, 200 mg, 300 mg & 400 mg tablets<br />

*


<strong>Pharmacist</strong> counseling tips for patients<br />

• Take SEROQUEL as prescribed by your doctor<br />

• You should contact your doctor if you feel the need to stop treatment<br />

• Dizziness or lightheadedness can be a side effect of SEROQUEL<br />

• Be sure to drink plenty of water to avoid becoming dehydrated or overheated<br />

• Drowsiness can be a side effect of SEROQUEL, especially when you first start<br />

taking it. Do not drive or operate machinery if you feel drowsy<br />

• You should avoid becoming pregnant while taking SEROQUEL<br />

• You should not breast-feed while taking SEROQUEL<br />

• You should avoid consuming alcoholic beverages<br />

• You should inform your doctor of any other prescription or over-the-counter<br />

medicine you are taking or plan to take<br />

(Tablets shown are<br />

not actual size)<br />

Important Safety Information<br />

25 mg<br />

•SEROQUEL is indicated for the treatment of acute manic episodes associated with bipolar I disorder, as either monotherapy or adjunct therapy with<br />

lithium or divalproex, and the treatment of schizophrenia. Patients should be periodically reassessed to determine the need for continued treatment<br />

• Elderly patients with dementia-related psychosis treated with atypical antipsychotic drugs are at an increased risk (1.6 to 1.7 times) of death<br />

compared to placebo (4.5% vs 2.6%, respectively). SEROQUEL is not approved for the treatment of patients with dementia-related psychosis<br />

•Prescribing should be consistent with the need to minimize the risk of tardive dyskinesia. A rare condition referred to as neuroleptic malignant<br />

syndrome has been reported with this class of medications, including SEROQUEL<br />

•Hyperglycemia, in some cases extreme and associated with ketoacidosis, hyperosmolar coma, or death, has been reported in patients treated<br />

with atypical antipsychotics, including SEROQUEL. Patients starting treatment with atypical antipsychotics who have or are at risk for diabetes<br />

should undergo fasting blood glucose testing at the beginning of and during treatment. Patients who develop symptoms of hyperglycemia should<br />

also undergo fasting blood glucose testing<br />

•Precautions include the risk of seizures, orthostatic hypotension, and cataract development<br />

•The most commonly observed adverse events associated with the use of SEROQUEL in clinical trials were somnolence, dry mouth, dizziness,<br />

constipation, asthenia, abdominal pain, postural hypotension, pharyngitis, SGPT increase, dyspepsia, and weight gain<br />

50 mg<br />

100 mg<br />

200 mg<br />

300 mg<br />

400 mg<br />

<strong>Pharmacist</strong> E-Link is an online communications network. <strong>Pharmacist</strong> E-Link is not an agent,<br />

employee or contractor of AstraZeneca Pharmaceuticals LP. Therefore, any reply to this e-mail will<br />

not be forwarded to AstraZeneca. Please contact AstraZeneca directly at 800.236.9933 with any<br />

questions or concerns you may have about their products.<br />

*All atypical prescriptions: Total prescriptions. Jan. 05-Jan. 06. New prescriptions. Sept. 04-Jan. 06.<br />

IMS Health. National Prescription Audit.<br />

*<br />

For full Prescribing Information, please click here<br />

http://www.astrazeneca-us.com/pi/seroquel.pdf<br />

AstraZeneca Pharmaceuticals LP<br />

25 mg, 50 mg, 100 mg, 200 mg, 300 mg & 400 mg tablets<br />

© 2006 AstraZeneca Pharmaceuticals LP. All rights reserved.<br />

SEROQUEL is a registered trademark of the AstraZeneca group of companies. 238165 3/06 www.SEROQUEL.com

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