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Small Animal Neuroradiology Small Animal Neuroradiology

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<strong>Small</strong> <strong>Animal</strong><br />

<strong>Neuroradiology</strong><br />

Kari L. Anderson, DVM<br />

College of Veterinary Medicine<br />

University of Minnesota<br />

<strong>Small</strong> <strong>Animal</strong><br />

<strong>Neuroradiology</strong><br />

• Knowledge of anatomy<br />

extremely important<br />

• Exact positioning critical<br />

– General anesthesia<br />

• Multiple views needed – skull<br />

• Complementary studies –<br />

myelogram, , CT, MRI<br />

Spinal Congenital<br />

Abnormalities<br />

• Common in “screw tail” breeds – Pug,<br />

Boston Terrier, Bulldog, Manx cat, but<br />

others as well<br />

• Often incidental<br />

• Spina bifida, hemivertebra, , block vertebra,<br />

transitional vertebra<br />

• May see spinal conformational abnormality –<br />

scoliosis, kyphosis, lordosis<br />

• Need additional imaging to assess neural<br />

tissue – myelogram, , CT, MRI<br />

Spinal Congenital<br />

Abnormalities<br />

• Spina bifida<br />

– Incomplete development of dorsal portion<br />

– Commonly in thoracic and lumbar<br />

– Often incidental but may have clinical<br />

signs<br />

– If clinical, varying degrees of protruding<br />

neural tissue occurs<br />

Spinal Congenital<br />

Abnormalities<br />

Radiographic findings -<br />

Spina bifida:<br />

• Unfused dorsal<br />

spinous process<br />

• Cleft dorsal spinous<br />

process<br />

• Lack of DSP or<br />

lamina<br />

Spinal Congenital<br />

Abnormalities<br />

• Block vertebra


Spinal Congenital<br />

Abnormalities<br />

• Hemivertebra<br />

Spinal Congenital<br />

Abnormalities<br />

• Transitional<br />

vertebra<br />

Atlantoaxial Subluxation<br />

• Miniature and toy breeds – Yorkshire<br />

terrier, Chihuahua, Toy Poodle,<br />

Pekinese<br />

• Young dogs<br />

• Developmental anomaly<br />

– Hypoplasia of dens<br />

– Cord compression caused by abnormal<br />

rotation of C2 into spinal canal<br />

Atlantoaxial Subluxation<br />

Radiographic findings:<br />

• Hypoplastic or<br />

absent dens<br />

• Widened space<br />

between C1 and C2<br />

• Abnormal<br />

angulation of C2<br />

Spondylosis Deformans<br />

• Degenerative change – related to<br />

instability and degeneration – may be<br />

secondary to many abnormalities<br />

• Common<br />

• Rarely clinically significant<br />

Intervertebral Disk<br />

Protrusion<br />

• Chondrodystrophoid breeds – Hansen Type<br />

1 herniation associated with chondroid<br />

metaplasia and disk degeneration<br />

• Nonchondrodystrophoid breeds – Hansen<br />

• Type 2 herniation associated with fibroid<br />

metaplasia and disk degeneration<br />

• Intervertebral disk degeneration:<br />

mineralized disk material in the disk space<br />

• Uncommon in cranial thoracic spine – WHY?


Intervertebral Disk<br />

Protrusion<br />

Intervertebral Disk<br />

Protrusion<br />

Radiographic findings:<br />

• Narrowed or wedged IVD<br />

space<br />

• Decreased size of IV foramen<br />

• Increased opacity of IV<br />

foramen<br />

• Narrowed articular facet space<br />

• Endplate sclerosis and<br />

spondylosis<br />

• Extradural compression on<br />

myelogram<br />

Cervical<br />

Spondylomyelopathy<br />

• AKA: Wobbler syndrome, cervical<br />

vertebral malformation-<br />

malarticulation syndrome, cervical<br />

vertebral instabilitiy<br />

• Common in middle age to older<br />

Dobes and younger Great Danes<br />

• Multiple underlying spinal<br />

abnormalities<br />

Cervical<br />

Spondylomyelopathy<br />

Radiographic findings:<br />

• Malformed<br />

vertebrae<br />

• Coning or stenosis<br />

of canal<br />

• Dorsal tipping of<br />

vertebrae<br />

• Facet proliferation<br />

and/or spondylosis<br />

Degenerative<br />

Lumbosacral Stenosis<br />

• Multifactorial disease:<br />

– Stenotic spinal canal<br />

– Lumbosacral malalignment<br />

– Lumbosacral instability<br />

– Herniated IVD<br />

– Spondylosis – may impinge on nerve<br />

roots<br />

• Large breed dogs – GSD


Degenerative<br />

Lumbosacral Stenosis<br />

Radiographic findings:<br />

• Best evaluated with CT<br />

or MRI<br />

• Endplate sclerosis and<br />

spondylosis<br />

• Narrowing and<br />

wedging of LS disk<br />

space<br />

• LS subluxation<br />

• Stenotic canal<br />

Discospondylitis<br />

• Infection of disk space with extension<br />

to adjacent vertebrae<br />

• Often multiple spaces affected<br />

• Generally hematogenous – commonly<br />

associated with urogenital infections<br />

• Staph spp, E. coli, Brucella canis,<br />

mycoses, mycobacterium<br />

Discospondylitis<br />

Spinal Neoplasia<br />

Radiographic findings:<br />

• Irregular endplate lysis<br />

• Bony sclerosis and<br />

proliferation<br />

• Widening or collapse of<br />

disk space<br />

• Spondylosis deformans<br />

Spinal Trauma<br />

Hydrocephalus<br />

• Congenital form – small, toy, and<br />

brachycephalic breeds (Yorkshire<br />

terrier, Chihuahua, Maltese, Toy<br />

Poodle, etc)<br />

• Radiographic abnormalities seen in<br />

congenital form<br />

• Better evaluated with US, CT, MRI


Hydrocephalus<br />

Radiographic findings:<br />

• Domed cranium<br />

• Fontanelles and<br />

open sutures<br />

• Cortical thinning<br />

• Homogenous<br />

appearance to brain<br />

Craniomandibular Osteopathy<br />

(CMO)<br />

• Young dogs 3-83<br />

8 months of age<br />

• Terrier breeds, Labs, Dobes, , GSD,<br />

Boxers<br />

• Osteoproliferative disorder that is self-<br />

limiting and slows at 7-87<br />

8 months of<br />

age<br />

• Secondary TMJ fusion can occur<br />

Craniomandibular Osteopathy<br />

(CMO)<br />

Radiographic findings:<br />

• Irregular, opaque<br />

new bone<br />

• Generally bilateral<br />

• Ankylosis of TMJ<br />

may occur<br />

• Ceases with<br />

maturity<br />

Otitis Externa and Media<br />

• Radiographs very helpful in evaluation<br />

– even better with CT<br />

• Otitis interna is clinical diagnosis!<br />

• Rule-out trauma, tumor,<br />

nasopharyngeal polyps<br />

Otitis Externa and Media<br />

Radiographic findings:<br />

• No abnormalities<br />

• Narrowing, obliteration,<br />

mineralization of<br />

external ear canals<br />

(otitisotitis externa)<br />

• Otitis media<br />

– Soft tissue/fluid opacity<br />

in tympanic bulla<br />

– Bony changes of bulla


Nondestructive Rhinitis<br />

Etiologies:<br />

• Infection<br />

• Foreign bodies<br />

• Nasopharyngeal polyps<br />

• Allergies<br />

• Coagulopathy<br />

Nondestructive Rhinitis<br />

Radiographic findings:<br />

• Increased soft<br />

tissue/fluid opacity of<br />

nasal passages and<br />

frontal sinuses<br />

• May see radiopaque<br />

foreign body<br />

• Should not see lysis<br />

unless very chronic<br />

infection or foreign<br />

body<br />

Destructive Rhinitis<br />

• Etiologies:<br />

– Nasal tumor<br />

– Fungal infection<br />

– Chronic infection or foreign bodies<br />

• Most common clinical sign is epistaxis<br />

• CT or MRI offers better evaluation<br />

Destructive Rhinitis<br />

Radiographic findings:<br />

• Early may mimic<br />

nondestructive<br />

• Irregular opacities in nasal<br />

passages and frontal<br />

sinuses<br />

• Bony lysis of ethmoid<br />

turbinates or nasal septum<br />

• May see extranasal<br />

extension


Hyperparathyroidism<br />

• Primary vs<br />

secondary<br />

Radiographic findings:<br />

• Loss of lamina dura<br />

• Demineralization of<br />

maxilla and<br />

mandible<br />

• Floating teeth

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