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Reverse Shoulder Arthroplasty Indications, Technique, and Results

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<strong>Technique</strong>s in <strong>Shoulder</strong> <strong>and</strong> Elbow Surgery 6(3):135–149, 2005<br />

Ó 2005 Lippincott Williams & Wilkins, Philadelphia<br />

<strong>Reverse</strong> <strong>Shoulder</strong> <strong>Arthroplasty</strong><br />

<strong>Indications</strong>, <strong>Technique</strong>, <strong>and</strong> <strong>Results</strong><br />

Armodios M. Hatzidakis, MD<br />

Western Orthopaedics P.C.<br />

Denver, CO<br />

Tom R. Norris, MD<br />

California Pacific Medical Center<br />

Department of Orthopaedic Surgery<br />

San Francisco, CA<br />

R E V I E W<br />

Pascal Boileau, MD<br />

Hôpital de L’Archet—University of Nice<br />

Department of Orthopaedic Surgery & Sports Traumatology<br />

Nice, France<br />

n ABSTRACT<br />

The surgical treatment of glenohumeral arthritis with rotator<br />

cuff deficiency is a difficult challenge. Hemiarthroplasty,<br />

the st<strong>and</strong>ard treatment at this time, is associated<br />

with satisfactory results in a ‘‘limited goals’’ perspective,<br />

but often the clinical results are unpredictable. Elevation<br />

after hemiarthroplasty approximately 90°. Pain relief<br />

can be inconsistent <strong>and</strong> can deteriorate over time.<br />

Constrained prostheses, including ball <strong>and</strong> socket<br />

<strong>and</strong> reverse ball <strong>and</strong> socket designs, were introduced<br />

in the 1970s to improve upon the results of arthroplasty<br />

in this challenging population. Unfortunately, clinical<br />

results were inconsistent using these designs, <strong>and</strong> rates<br />

of mechanical loosening <strong>and</strong> revision were high. The only<br />

design that survived has been the prosthesis of Paul<br />

Grammont (Dijon, France). His Delta III Prosthesis<br />

(DePuy, Warsaw IN) has been in use in its current form<br />

since 1992, with good clinical results <strong>and</strong> relatively low<br />

mechanical loosening rates compared with the ball <strong>and</strong><br />

socket <strong>and</strong> reversed ball <strong>and</strong> socket designs of the past.<br />

This design is also utilized by the Tornier Aequalis<br />

<strong>Reverse</strong>d Prosthesis (Tornier SA, Montbonnot, FR). In<br />

Europe, <strong>and</strong> more recently in the United States, this prosthetic<br />

design has proven useful in treating patients with<br />

glenohumeral arthritis with extensive cuff deficiency,<br />

Address correspondence <strong>and</strong> reprint requests to: Pascal Boileau, MD,<br />

Professor <strong>and</strong> Chairman. Dept of Orthopaedic Surgery & Sports<br />

Traumatology, Hôpital de L’Archet—University of Nice, 151 Route de<br />

St Antoine de Ginestière, 06202 Nice, France (e-mail: boileau.p@<br />

chu-nice.fr).<br />

proximal humeral fracture nonunions <strong>and</strong> malunions,<br />

<strong>and</strong> failed arthroplasty with a deficient rotator cuff. Predictably<br />

good results can be obtained in these difficult<br />

circumstances, with good pain relief <strong>and</strong> elevation often<br />

exceeding the horizontal. Active rotation, however, is<br />

usually not improved. Complication rates are low in<br />

patients with cuff tear arthritis <strong>and</strong> relatively high in revision<br />

arthroplasty cases. As with all revision operations,<br />

be they failed cuff repairs or failed prosthetic replacements,<br />

there is a higher risk of lingering low grade infections.<br />

<strong>Results</strong> can be optimized <strong>and</strong> complications<br />

minimized with proper patient selection, fastidious surgical<br />

technique, <strong>and</strong> proper postoperative rehabilitation.<br />

n HISTORICAL PERSPECTIVE<br />

Treatment of the rotator cuff deficient shoulder with arthritis<br />

has proven a difficult surgical challenge. Because<br />

pain relief was the goal <strong>and</strong> results of function were<br />

usually poor, Neer stated that arthroplasty for rotator cuff<br />

arthropathy should be judged by ‘‘limited goals’’ criteria.<br />

Multiple studies have confirmed empirical evidence that<br />

hemiarthroplasty for cuff deficient arthritis has somewhat<br />

unpredictable results. 1–8 Total shoulder arthroplasty has<br />

been ab<strong>and</strong>oned for this group due to the loss of force<br />

couple of the supraspinatus-deltoid <strong>and</strong> subsequent early<br />

glenoid loosening. This is attributable to the ‘‘rocking horse<br />

phenomenon’’ with upward subluxation onto the glenoid<br />

rim, leading to loosening. 9 Although hemiarthroplasty<br />

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Hatzidakis et al<br />

provides a smooth surface for articulation with the native<br />

glenoid <strong>and</strong> acromion, the biomechanical stabilization of<br />

the fulcrum for elevation is still deficient. Sometimes<br />

the intact remaining cuff, deltoid, <strong>and</strong> ‘‘acetabularized’’<br />

acromial arch can compensate for this lack of fulcrum,<br />

but good early results can deteriorate secondary to progressive<br />

erosion of the prosthetic head into the glenoid<br />

<strong>and</strong> acromion (Fig. 1). Pain relief is often good initially,<br />

but can deteriorate over time with glenoid arthritis <strong>and</strong><br />

acromial wear or fracture. The results of hemiarthroplasty<br />

are even more inconsistent in patients who have<br />

a ‘‘pseudoparalytic’’ shoulder, in whom attempts at elevation<br />

are rewarded only with an ineffective shrug. As we<br />

have gained more experience in teasing out subtle causes<br />

of this ineffectual shrug associated with massive rotator<br />

cuff tears, we wish to differentiate between those with<br />

irreparable cuff tears with true pseudo paralysis of the<br />

shoulder (PPS) <strong>and</strong> anterior superior subluxation due<br />

to muscle imbalance, <strong>and</strong> those patients with painful loss<br />

of elevation (PLE) due to an hourglass or otherwise painful<br />

biceps. With PPS humeral head arthroplasty <strong>and</strong><br />

tendon reconstructions have been ineffectual, whereas<br />

with PLE arthroscopic biceps tenotomy has allowed<br />

many to regain overhead elevation.<br />

Multiple constrained <strong>and</strong> semiconstrained prostheses<br />

have been designed to compensate for the loss of rotational<br />

fulcrum caused by severe degeneration of the rotator<br />

cuff. Previous reverse prostheses were designed<br />

by Reeves, Liverpool, Bayley, Neer <strong>and</strong> Averill, Kolbel,<br />

Kessel, Fenlin, <strong>and</strong> Gerard in the 1970s <strong>and</strong> 1980s. Disappointing<br />

results <strong>and</strong> high complication rates led to<br />

ab<strong>and</strong>onment of these prostheses. 10,11 The common denominator<br />

for failure was loosening of the glenoid<br />

component. The center of rotation was lateral to the glenoid<br />

<strong>and</strong> created high torque on the relatively frail<br />

glenoid. The reverse prosthesis (RP) of Professor Paul<br />

Grammont (Dijon, France) was also designed specifically<br />

for the rotator cuff deficient shoulder. 12–14 It differed<br />

from previous prostheses in that the glenoid component<br />

was larger, <strong>and</strong> its center of rotation was medialized<br />

on to the glenoid face, thus decreasing torque on the<br />

component-bone fixation. The humeral neck angle is<br />

nonanatomic <strong>and</strong> made more horizontal. This increases<br />

stability of the new glenohumeral joint. In short to<br />

medium term studies up to 10 years, this prosthesis<br />

has succeeded where others have failed, predominately<br />

because of its favorable biomechanical characteristics.<br />

Short <strong>and</strong> medium-term follow-up studies in Europe have<br />

determined that this specific design leads to functional<br />

restoration of elevation <strong>and</strong> favorable survivorship,<br />

with relatively low rates of early glenoid loosening. 15–22<br />

Two current versions of the prosthesis have been used<br />

in Europe; since 1992 for the Delta <strong>and</strong> since 1998 for<br />

the Tornier. Respectively, these prostheses have been<br />

available in the United States since FDA approval in<br />

November 2003 (DePuy, Warsaw IN) <strong>and</strong> May 2004<br />

(Tornier SA, Montbonnot, FR).<br />

Biomechanics<br />

The RP design of Grammont combines a large hemispherical<br />

glenoid component (36 or 42 mm diameter)<br />

that has a medialized center of rotation <strong>and</strong> secure screw<br />

fixation to the glenoid, with a cemented humeral component<br />

that has a more horizontally aligned (155°) metaphyseal<br />

neck with a reverse hemispherical polyethylene<br />

cup that perfectly conforms to the glenosphere (Fig. 2).<br />

FIGURE 1. A, Humeral head replacement placed for shoulder arthritis with a massive irreconstructible deficiency of the<br />

supraspinatus <strong>and</strong> subscapularis. B, The humeral head ceases to ‘‘roll’’ on the glenoid <strong>and</strong> turns into a ‘‘wedge,’’ leading<br />

to (C) superior erosion of the acromion <strong>and</strong> glenoid. D, The functional result is poor, with forward flexion of approximately<br />

30° <strong>and</strong> persistent pain.<br />

136 <strong>Technique</strong>s in <strong>Shoulder</strong> <strong>and</strong> Elbow Surgery


<strong>Reverse</strong> <strong>Shoulder</strong> <strong>Arthroplasty</strong><br />

This design allows for more range of motion than reverse<br />

ball <strong>and</strong> socket designs of the past (Fig. 3). With proper<br />

placement of this prosthesis, the center of humeral rotation<br />

is made more distal, placing the deltoid muscle at<br />

greater tension (Fig. 4), <strong>and</strong> medialized, which recruits<br />

more deltoid muscle fibers for elevation <strong>and</strong> increases<br />

the deltoid lever arm. 3 These factors increase the deltoid’s<br />

biomechanical ability to generate rotational torque,<br />

elevating the arm on a new stable fulcrum (the glenosphere).<br />

The medialized center of rotation decreases<br />

torsional forces on glenosphere fixation, decreasing the<br />

tendency of the glenoid component to loosen (Fig. 5).<br />

FIGURE 2. The <strong>Reverse</strong>d <strong>Shoulder</strong> ProsthesisÔ (Tornier<br />

Inc., Tornier SA, Montbonnot, FR).<br />

n INDICATIONS/<br />

CONTRAINDICATIONS<br />

There are 3 specific circumstances where we have found<br />

the RP to be useful. The common characteristic of these<br />

indications is that the biomechanical fulcrum for elevation<br />

is lost, either via irreparable loss of the rotator cuff<br />

or severe malposition of the tuberosities.<br />

The first indication is primary osteoarthritis of the<br />

shoulder with massive irreparable cuff tear, in patients<br />

with secondary osteoarthritis or osteonecrosis who have<br />

a ‘‘decompensated’’ cuff deficiency (‘‘Cuff Tear Arthritis,’’<br />

CTA). These patients typically suffer from significant<br />

pain <strong>and</strong> cannot lift their arms to the horizontal<br />

despite attempts to strengthen the deltoid <strong>and</strong> remaining<br />

intact cuff. Many of these patients have had one or many<br />

attempts to repair the rotator cuff, <strong>and</strong> some may exhibit<br />

FIGURE 3. A reversed design of the<br />

past utilizes a small prosthetic head with<br />

highly constrained humeral cup, leading<br />

to decreased potential range of motion<br />

compared with the Grammont design.<br />

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Hatzidakis et al<br />

FIGURE 4. A, Deltoid elevation torque<br />

in the cuff deficient shoulder is decreased<br />

secondary to proximal humeral<br />

migration, whereas elevation torque in<br />

the Grammont reverse shoulder (B) is<br />

increased because of a medialized<br />

<strong>and</strong> lowered center of rotation (L2 3<br />

F2 . L1 3 F1).<br />

marked anterosuperior escape of the humeral head with<br />

attempted elevation. Patients with anterosuperior escape<br />

are usually not helped by humeral hemiarthroplasty, even<br />

with attempted coracoacromial arch reconstruction,<br />

making them ideal c<strong>and</strong>idates for reversed shoulder<br />

arthroplasty.<br />

The second indication is severe fracture sequelae<br />

(FS). These patients have had a displaced, usually comminuted<br />

fracture of the proximal humerus with tuberosity<br />

malposition or nonunion. Although an unconstrained<br />

prosthesis can reliably provide pain relief <strong>and</strong> restore<br />

function in those cases where the prosthesis can be<br />

‘‘adapted’’ to slight tuberosity malalignment, patients<br />

who have unhealed tuberosities or require osteotomy of<br />

the greater tuberosity do not typically fare as well. 23 An<br />

RP can consistently provide both pain relief <strong>and</strong> restoration<br />

of active elevation in this specific patient group.<br />

The third indication for reverse shoulder arthroplasty<br />

is revision of previously failed arthroplasty. Typically<br />

these patients have had a hemiarthroplasty placed for<br />

CTA or comminuted proximal humerus fracture. In<br />

CTA cases, common causes for failure are loss of the<br />

FIGURE 5. A, The lateralized center of<br />

rotation <strong>and</strong> constrained design of previous<br />

reverse designs leads to more<br />

shear forces on glenoid fixation compared<br />

with the less constrained, medialized<br />

center of rotation of the Grammont<br />

design (B).<br />

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<strong>Reverse</strong> <strong>Shoulder</strong> <strong>Arthroplasty</strong><br />

fulcrum for elevation (dysfunctional cuff or postoperative<br />

subscapularis rupture with resulting instability)<br />

<strong>and</strong> progressive erosion into the glenoid <strong>and</strong>/or acromion.<br />

This leads to increased pain <strong>and</strong> decreased function.<br />

Common causes for failure in fracture cases are<br />

malposition of the component <strong>and</strong> tuberosity malunion<br />

or nonunion. In CTA <strong>and</strong> post-fracture cases, revision<br />

hemiarthroplasty or conversion to total shoulder arthroplasty<br />

with soft tissue <strong>and</strong>/or bony procedures is either<br />

unpredictable or contraindicated. At times, even with apparent<br />

cuff restoration, the scarring <strong>and</strong> multiple operations<br />

result in the cuff not functioning effectively. Motion<br />

<strong>and</strong> function are lost despite heroic efforts with surgery<br />

<strong>and</strong> rehabilitation. In our experience, RP placement in<br />

these cases is less beneficial than in primary CTA<br />

patients, but the results seem to be more satisfactory than<br />

with other procedures that have been described. With the<br />

revision prosthesis cases, particularly those with multiple<br />

previous operations, low grade infections are more common.<br />

All precautions are observed to anticipate, diagnose,<br />

<strong>and</strong> treat any potential sepsis.<br />

Relative <strong>Indications</strong><br />

Acute fractures <strong>and</strong> old nonunions in the very elderly<br />

where rotator cuff rehabilitation is suboptimal is an example<br />

where early results are reported to be good, but longer<br />

follow-up is lacking. Early European (D. Mole) <strong>and</strong><br />

U.S. experience with the RP have been encouraging for<br />

the very elderly patient with acute proximal humeral<br />

4-part fractures. Using the prosthesis in these patients<br />

can be beneficial, as the need for tuberosity union is<br />

bypassed <strong>and</strong> post operative rehabilitation is expedited.<br />

Contraindications<br />

This prosthesis should not be used in primary osteoarthritis<br />

or osteonecrosis of the shoulder when the articular<br />

surface–tuberosity relationships are normal <strong>and</strong> the rotator<br />

cuff is intact <strong>and</strong> functional. These patients are best<br />

served with a third generation anatomic unconstrained<br />

total shoulder arthroplasty. The RP also should not be<br />

used if the patient exhibits marked deltoid deficiency,<br />

as the shoulder will not function well <strong>and</strong> will be prone<br />

to dislocate. A history of previous infection is a relative<br />

contraindication, as recurrence in these patients is high.<br />

Finally, the RP should be used only sparingly in patients<br />

less than 65 years old, as long-term survivorship <strong>and</strong><br />

complication rates are unknown.<br />

<strong>Reverse</strong>d <strong>Shoulder</strong> ProsthesisÔ is available through<br />

Tornier SA, (Montbonnot, FR). For practical purposes<br />

of this technique description, the Aequalis <strong>Reverse</strong>d<br />

<strong>Shoulder</strong> Prosthesis will be referenced, although the<br />

steps are somewhat similar for the Delta III. The glenoid<br />

component consists of a circular baseplate (metaglene),<br />

which is fixed to the native glenoid with 2 compression<br />

screws <strong>and</strong> 2 locked screws (Fig. 6). In the United States,<br />

the surface of the plate that contacts the glenoid bone is<br />

grit blasted <strong>and</strong> roughened to aid with ongrowth. The superior<br />

<strong>and</strong> inferior holes in the baseplate are threaded<br />

<strong>and</strong> angled 20° superiorly <strong>and</strong> inferiorly, respectively.<br />

The anterior <strong>and</strong> posterior screw holes are not threaded,<br />

leaving flexibility to place the anterior <strong>and</strong> posterior<br />

compression screws into the best bone that is available.<br />

The articulating glenoid component, or glenosphere, is<br />

a smooth cobalt-chrome hemisphere that is fixed to the<br />

baseplate via a Morse taper <strong>and</strong> countersunk set screw<br />

(Fig. 7), placing the center of rotation at the level of<br />

the glenoid/baseplate interface.<br />

The humeral component is designed for cemented<br />

use only, with a cup shaped metaphyseal component that<br />

is fixed to stems of variable lengths via a screw-on mechanism.<br />

The metaphyseal cut–shaft angle is 155°. This<br />

horizontal inclination leads to stability of the metaphyseal<br />

polyethylene cup when articulating with the glenosphere.<br />

In the Aequalis <strong>Reverse</strong>d <strong>Shoulder</strong>Ô system,<br />

polyethylene inserts of increasing diameter (6 mm,<br />

9 mm, <strong>and</strong> 12 mm) (Fig. 8) are available, in addition<br />

to a metal metaphyseal offset extension (9 mm). With<br />

the metaphyseal extension, 15 mm, 18 mm, <strong>and</strong> 21 mm<br />

offsets become available. Availability of these different<br />

polyethylene thicknesses <strong>and</strong> offset lengths are particularly<br />

useful in the revision situation, when bone loss<br />

makes prosthetic tension more difficult to set precisely<br />

via cementation of the humeral component. At the time<br />

of this writing, the Delta III prosthesis (DePuy, Warsaw<br />

IN) has a 6 mm <strong>and</strong> 9 mm insert, the 9 mm metal extension,<br />

<strong>and</strong> a deeper ‘‘retentive’’ cup option (6 mm) with<br />

a deeper thinner polyethylene insert.<br />

n COMPONENTS AND<br />

MANUFACTURERS<br />

Currently the RP design of Grammont is offered by two<br />

prosthetic manufacturers. The Delta IIIÔ prosthesis is<br />

available through DePuy (Warsaw IN), <strong>and</strong> the Aequalis<br />

FIGURE 6. The baseplate is attached to the native glenoid<br />

by a press-fit central peg, 2 compression screws (anterior<br />

<strong>and</strong> posterior), <strong>and</strong> 2 locking screws (superior <strong>and</strong> inferior).<br />

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Hatzidakis et al<br />

wear of the glenoid, giving the surgeon an idea of how<br />

much reaming is required inferiorly to create ideal glenosphere<br />

inferior tilt (0–15°). In cases of very severe superior<br />

glenoid erosion, an iliac crest bone graft can be<br />

planned to fill the bony deficiency. In special circumstances,<br />

the humeral head may also be harvested after<br />

removing any remaining articular cartilage <strong>and</strong> then used<br />

to bone graft the glenoid defect with or without supplemental<br />

iliac crest graft (Fig. 9).<br />

FIGURE 7. The glenosphere is fixed securely to the baseplate<br />

via a Morse taper <strong>and</strong> countersunk set screw.<br />

n PREOPERATIVE PLANNING<br />

Preoperative radiographs include a true AP of the shoulder<br />

with the arm in neutral rotation (Grashey view), an<br />

axillary lateral view, <strong>and</strong> a scapular lateral view. We typically<br />

obtain a long AP of the humeral shaft with the AP<br />

shoulder view to ensure that the humeral canal is normal<br />

<strong>and</strong> a cemented humeral component can be inserted without<br />

complication. In addition, a Computerized Tomography<br />

scan is obtained of the shoulder, including the entire<br />

scapula with 2 mm cuts, so that fatty atrophy of the cuff 25<br />

12 can be examined <strong>and</strong> accurate 2-dimensional coronal<br />

reconstructions can be obtained. The axial cuts give the<br />

surgeon an estimate of glenoid size <strong>and</strong> the feasibility of<br />

glenoid implantation, as the glenoid can occasionally be<br />

asymmetrically worn. The axial cuts also are good indicators<br />

of the degree of fatty infiltration that has occurred<br />

in the posterior cuff, an important prognostic indicator<br />

for regaining some functional external rotation 16 . The<br />

coronal reconstructions show the amount of superior<br />

FIGURE 8. The <strong>Reverse</strong>d <strong>Shoulder</strong> ProsthesisÔ (Tornier<br />

Inc., Tornier SA, Montbonnot, FR) has 3 humeral polyethylene<br />

inserts of different thicknesses, in addition to a 9 mm<br />

metal extension (not pictured), to optimize deltoid tension<br />

<strong>and</strong> prosthetic stability.<br />

n TECHNIQUE<br />

For the purposes of this paper, our technique for implantation<br />

will be described for the ‘‘virgin’’ CTA case.<br />

Although Grammont initially described a transacromial<br />

approach for placement of this prosthesis, most<br />

surgeons now use a deltopectoral or anterosuperior approach.<br />

We prefer the deltopectoral approach, as it spares<br />

the deltoid insertion <strong>and</strong> axillary nerve <strong>and</strong> is highly useful<br />

in prosthetic revision surgery.<br />

Exposure <strong>and</strong> Humeral Preparation<br />

The deltopectoral approach is st<strong>and</strong>ard, with an incision<br />

started just superior <strong>and</strong> medial to the coracoid process<br />

<strong>and</strong> extended obliquely distally to the deltoid insertion<br />

at the mid-arm. The subcutaneous tissues are dissected<br />

with knife <strong>and</strong> electrocautery. The cephalic vein is retracted<br />

laterally with the deltoid <strong>and</strong> the deltopectoral<br />

interval fully dissected from the clavicle to the insertion<br />

of the pectoralis major on the proximal humerus. The<br />

proximal humerus has typically migrated superiorly.<br />

The coracoacromial ligament is visualized, followed<br />

by removal of the subscapularis bursa <strong>and</strong> identification<br />

of the conjoint tendon. The deltoid is retracted laterally<br />

using a broad Richardson retractor, <strong>and</strong> the conjoint tendon<br />

gently retracted medially using a narrow blunt<br />

Richardson retractor. The remaining subscapularis is<br />

tagged with medially placed #5 braided suture, <strong>and</strong> the<br />

subscapularis is tenotomized 1 cm from its insertion. Release<br />

of the subscapularis continues inferiorly, releasing<br />

the inferior muscular fibers <strong>and</strong> inferior capsule from the<br />

humerus while an assistant provides gentle progressive<br />

external rotation to the arm. The superior 1 cm of the<br />

pectoralis insertion is also occasionally released to assist<br />

in ease of exposure.<br />

Superiorly, the cuff is usually absent. In cases of previous<br />

failed cuff repair, suture <strong>and</strong> scar are removed, <strong>and</strong><br />

the interval between the cuff <strong>and</strong> acromion dissected<br />

sharply or with electrocautery. The posterior cuff <strong>and</strong> tuberosity<br />

is freed from the overlying deltoid sharply or<br />

with electrocautery, taking care not to injure the axillary<br />

nerve inferiorly.<br />

At this point the humerus is readily dislocated anteriorly<br />

<strong>and</strong> superiorly for humeral preparation. The<br />

140 <strong>Technique</strong>s in <strong>Shoulder</strong> <strong>and</strong> Elbow Surgery


<strong>Reverse</strong> <strong>Shoulder</strong> <strong>Arthroplasty</strong><br />

FIGURE 9. One potential solution for glenoid bone loss (TRN): Rheumatoid arthritis <strong>and</strong> Arthrokatadysis of the upper glenoid.<br />

The defect in the glenoid was bone grafted with the osteotomized humeral head (HH) as it fit the erosion perfectly (A).<br />

The HH had to be osteotomized more vertically than usual for the st<strong>and</strong>ard approach for the <strong>Reverse</strong>, then temporarily fixed<br />

with Steinmann pins <strong>and</strong> then fixed with the baseplate (B). Ideally the post of the baseplate reaches the native scapula.<br />

highest, most lateral point on the humeral head is identified<br />

as a reference point. A hole is created with an awl;<br />

the head cutting guide is inserted into the humeral shaft<br />

via this hole, <strong>and</strong> retroversion is determined using a pin<br />

set at the desired degree. Grammont advocated a version<br />

of 0°. We typically set the cut between 0 <strong>and</strong> 20° of retroversion,<br />

as this version seems to allow ‘‘filling’’ of the<br />

metaphysis without anterior cortical protrusion, <strong>and</strong> may<br />

allow for slightly improved functional external rotation.<br />

Nonetheless, the optimal retroversion for this component<br />

has yet to be defined. A minimal head cut is made parallel<br />

to the undersurface of the neck cutting guide, taking<br />

care not to hit the shaft of the cutting guide with the saw<br />

(Fig. 10). The guide is removed <strong>and</strong> the cut completed<br />

with either the saw or an osteotome. Cancellous bone<br />

is harvested from the remaining humeral head <strong>and</strong> saved<br />

to graft the glenoid central hole prior to inserting the<br />

baseplate. Then the metaphyseal ‘‘cheese grater’’ reamer<br />

is used to remove remaining cancellous bone from the<br />

proximal humerus to allow metaphyseal component<br />

placement (Fig. 11). There are 2 sizes of reamers, 36<br />

<strong>and</strong> 42 mm. The size that fits best is usually 36 mm,<br />

FIGURE 10. The humeral cutting guide<br />

<strong>and</strong> version rod (A). The version rod is<br />

aligned with the forearm to determine<br />

the version of the humeral head cut (B).<br />

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but for larger individuals or those with previous prosthetic<br />

instability, preparation for a 42 mm component may be<br />

preferred. The decision on reamer size is based on preoperative<br />

planning <strong>and</strong> intraoperative estimation of humeral<br />

<strong>and</strong> glenoid size.<br />

Distal metaphyseal reaming is then performed with<br />

a long conical reamer, inserting the reamer so that the<br />

height l<strong>and</strong>mark is level with the highest part of the humeral<br />

cut. Diaphyseal reaming is then performed sequentially<br />

with reamers of 6.5, 9, 12, <strong>and</strong> 15 mm until the<br />

reamer comes into contact with diaphyseal cortical bone.<br />

If the reamer of a specific size reaches the appropriate<br />

depth as noted by the height l<strong>and</strong>mark with chatter,<br />

reaming is stopped. Preparing the canal more aggressively<br />

risks fracturing the humerus as well as not having an adequate<br />

cement mantle.<br />

The humeral trial is then assembled <strong>and</strong> retroversion<br />

rod set to 0 to 20°, according to the preference of the<br />

surgeon. The trial is then inserted with manual pressure,<br />

followed by light impaction with a mallet. A plastic<br />

cut protector is then placed into the metaphysis of the<br />

component to protect the trial component during glenoid<br />

preparation. At times the medial head still protrudes<br />

<strong>and</strong> needs trimming to facilitate retraction <strong>and</strong> glenoid<br />

exposure.<br />

Glenoid Preparation<br />

Homan <strong>and</strong> Kolbel retractors are used to retract the soft<br />

tissues <strong>and</strong> proximal humerus while a circumferential<br />

capsulotomy <strong>and</strong> labral excision are performed. The<br />

FIGURE 11. A cup is made in the native proximal humerus<br />

using the power ‘‘cheese grater’’ reamer to accept the humeral<br />

metaphyseal component.<br />

origin of the long head of the triceps is released from<br />

the inferior glenoid, <strong>and</strong> the lateral pillar of the scapula<br />

is palpated. A 2-prong Tiemannn Capsular retractor is<br />

placed against the lateral pillar/scapular neck. This serves<br />

as a reference guide later for the superior-inferior orientation<br />

of the baseplate, so that the inferior screw be<br />

placed down the center of the axial border of the scapula.<br />

Glenoid osteophytes are removed to reveal the true glenoid<br />

anatomic shape <strong>and</strong> more correctly identify the base<br />

of glenoid bone that is most solid for baseplate (metaglene)<br />

placement. The central hole guide is assembled<br />

<strong>and</strong> placed with the h<strong>and</strong>le inferior for the deltopectoral<br />

approach. The inferior most edge of the guide is placed<br />

against the inferior most edge of the glenoid. This ensures<br />

that the metaglene is placed against the glenoid<br />

as inferior as possible. Alternatively, one may prefer to<br />

invert the baseplate <strong>and</strong> use it as a guide to ensure more<br />

inferior placement. The goal is to have the glenosphere<br />

inferior enough <strong>and</strong> tilted inferiorly a few degrees to decrease<br />

any contact of the polyethylene insert with the<br />

scapula. This nuance is the recent attempt to prevent<br />

scapular notching. Based on preoperative CT scanning<br />

the guide is angled inferiorly to create an inferior tilt<br />

to the reamed surface of 0–15°. The central hole is then<br />

drilled with a 6 mm bit, which has a self-stop (Fig. 12).<br />

The guide is then removed, followed by placing the flat<br />

glenoid reamer (Fig. 12). The reamer is started away<br />

from the bone, then pushed slowly into the glenoid to<br />

gently flatten the glenoid face, conservatively removing<br />

bone to preserve as much of the subchondral plate as possible.<br />

Once a uniformly flat surface has been created<br />

<strong>and</strong> a 1–2 mm groove is created circumferentially, the<br />

reaming is complete. The groove must be created to<br />

allow placement of the baseplate flush against the bone.<br />

The reamer is removed <strong>and</strong> the glenoid central hole drill<br />

guide placed, followed by over-drilling of the central hole<br />

with a 7.5 mm drill with a self-stop (Fig. 13). The cancellous<br />

bone graft is impacted in the post hole. The baseplate<br />

inserter is assembled <strong>and</strong> the 8.0 mm baseplate<br />

central post is impacted into the 7.5 mm drilled hole for<br />

a press-fit into the scapula.<br />

There is an ‘‘up’’ <strong>and</strong> ‘‘down’’ marker on the inserter<br />

with a vertical line that allows orientation of the baseplate<br />

so that the inferior drill hole is aligned with the inferior<br />

pillar of the scapular neck (Fig. 14). This ensures<br />

placement of an inferior screw that is as long as possible.<br />

The baseplate is impacted against the glenoid bone with<br />

several sharp blows with a mallet. The inserter is gently<br />

removed, leaving the baseplate in place. The positioning<br />

of the superior <strong>and</strong> inferior locking screws is most critical.<br />

We prefer to place the inferior screw first to set the<br />

rotation of the baseplate. The threaded drill guide is<br />

screwed into the metaglene screw hole. A long 3 mm drill<br />

bit is inserted into the guide, drilling through the face of<br />

142 <strong>Technique</strong>s in <strong>Shoulder</strong> <strong>and</strong> Elbow Surgery


<strong>Reverse</strong> <strong>Shoulder</strong> <strong>Arthroplasty</strong><br />

FIGURE 12. A center hole is drilled for<br />

reaming using the appropriate guide<br />

(A), followed by reaming the glenoid flat<br />

(B), preferably with a 10° downward tilt.<br />

the glenoid <strong>and</strong> along the inferior pillar of the scapula<br />

(Fig. 15). After the far cortex is breached, the length is<br />

measured <strong>and</strong> the inferior screw placed. It is fully advanced<br />

temporarily, ‘‘locked’’ into the baseplate, keeping<br />

it from rotating during subsequent screw placement. The<br />

superior screw is then drilled, measured, <strong>and</strong> inserted.<br />

The anterior <strong>and</strong> posterior screws are then drilled <strong>and</strong><br />

proper lengths measured (Fig. 16). These 2 screws are<br />

then inserted but not tightened until the superior <strong>and</strong><br />

inferior screws are temporarily loosened, unlocking them<br />

from the baseplate. The anterior <strong>and</strong> posterior screws are<br />

then tightened sequentially to achieve compression of the<br />

baseplate against the prepared glenoid surface. Once full<br />

compression is obtained with the anterior <strong>and</strong> posterior<br />

screws, the superior <strong>and</strong> inferior screws are locked to<br />

achieve final baseplate fixation. The baseplate should<br />

be very well fixed to the bone. This requires at least<br />

3 of the 4 screws having good purchase.<br />

The glenosphere of choice (36 or 42 mm) is then<br />

guided to the metaglene using a screwdriver (Fig. 17).<br />

The glenosphere is gently pressed onto the Morse taper<br />

of the metaglene <strong>and</strong> the screwdriver is removed. The<br />

glenosphere is firmly seated onto the Morse taper of the<br />

metaglene using a polyethylene impactor <strong>and</strong> several<br />

sharp blows of the mallet. Final glenosphere fixation is<br />

secured by tightening the center set screw, which threads<br />

into a mating thread on the inside of the center peg of<br />

the metaglene (Fig. 17). Care is taken throughout these<br />

steps to ensure that soft tissue is completely cleared<br />

from the periphery of the glenoid so that incomplete<br />

glenosphere-metaglene fixation <strong>and</strong> postoperative lucent<br />

lines do not occur.<br />

FIGURE 13. The center hole is widened<br />

slightly by the 7.5 mm drill bit <strong>and</strong> guide<br />

so it will accept the 8 mm diameter<br />

central peg of the baseplate with a good<br />

press-fit.<br />

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Hatzidakis et al<br />

FIGURE 14. The glenoid baseplate (in<br />

this case coated with hydroxyapatite)<br />

is impacted onto the glenoid, with the<br />

lower mark aligned with the lateral pillar<br />

of the scapula.<br />

Glenohumeral Trialing, Humeral Component<br />

Implantation, <strong>and</strong> Final Reduction<br />

After the glenosphere is firmly implanted, the humerus<br />

can be redislocated out of the incision. Care is taken<br />

not to scratch the glenosphere during the dislocation<br />

maneuver. A 6 mm trial humeral insert is then placed<br />

<strong>and</strong> impacted into the humeral trial metaphyseal cup<br />

(Fig. 18). A trial reduction is performed. The humeral<br />

component should rotate nicely without signs of instability.<br />

Gentle traction is applied to the arm to perform a<br />

‘‘shuck’’ maneuver. There should be less than 1 mm of<br />

diastasis between the humeral cup <strong>and</strong> glenosphere during<br />

this maneuver to ensure proper stability. If the shoulder<br />

cannot be reduced with a 6 mm insert, then the trial<br />

is removed, adhesions lysed, <strong>and</strong> additional proximal<br />

humeral bone resected if necessary.<br />

Once it is determined that the shoulder will reduce,<br />

the proximal humeral component is cemented. A<br />

cement restrictor is inserted <strong>and</strong> the humeral shaft<br />

meticulously dried. Cementing technique is very important<br />

for this prosthesis, as there may be more problems<br />

with humeral loosening with the <strong>Reverse</strong> Prosthesis than<br />

with unconstrained total shoulder replacement. Press fit<br />

placement of the humeral component is not recommended<br />

at this time following some earlier experience<br />

with subsidence.<br />

FIGURE 15. Correct position of the<br />

baseplate is confirmed by first drilling<br />

the inferior locking screw hole with a long<br />

guide that threads into the plate.<br />

144 <strong>Technique</strong>s in <strong>Shoulder</strong> <strong>and</strong> Elbow Surgery


<strong>Reverse</strong> <strong>Shoulder</strong> <strong>Arthroplasty</strong><br />

FIGURE 16. With the superior <strong>and</strong> inferior<br />

locking screws partially advanced<br />

(not locked into the plate), the anterior<br />

<strong>and</strong> posterior screws are drilled <strong>and</strong><br />

filled with 4.5 mm screws, compressing<br />

the baseplate to the glenoid bone. The<br />

superior <strong>and</strong> inferior screws are then advanced,<br />

‘‘locking’’ the fixation construct.<br />

After the humeral component is well fixed with cement,<br />

the 6 mm trial insert is placed into the metaphysis<br />

<strong>and</strong> the shoulder reduced. If the tension is adequate, the<br />

shoulder is redislocated <strong>and</strong> the final polyethylene liner<br />

impacted into the metaphyseal cup (Fig. 19). If there is<br />

insufficient tension, gradually increasing sizes of liner<br />

trials are used to obtain the optimum fit. In the primary<br />

CTA case it is rare that a liner over 9 mm is required, but<br />

the larger 12 mm liner <strong>and</strong> 9 mm metaphyseal extension<br />

are often essential for the revision situation.<br />

After the shoulder is reduced with final implants in<br />

position, the subscapularis is repaired via 3 to 4 tendon<br />

to tendon sutures, occasionally augmenting the repair<br />

with transosseous sutures if the remaining tendon tag<br />

on the humerus is insufficient. The deltopectoral interval<br />

is closed over a drain, with a running absorbable suture.<br />

The skin is closed in routine fashion. Postoperative radiographs<br />

are obtained in the recovery room (Fig. 20).<br />

n POSTOPERATIVE MANAGEMENT<br />

The shoulder is immobilized in slight abduction <strong>and</strong> in<br />

near-neutral rotation. Gentle passive motion in all planes<br />

is started immediately, taking care not to push the limit of<br />

intraoperative motion measurements. Active assisted<br />

motion is started at 3 to 4 weeks postoperatively, followed<br />

by active motion at approximately 6 weeks<br />

postoperative. The immobilizer is discontinued at this<br />

FIGURE 17. The glenosphere is lightly<br />

advanced onto the reverse Morse taper<br />

of the baseplate using the center screwdriver.<br />

The screwdriver is then removed<br />

<strong>and</strong> a polyethylene impactor applied to<br />

the glenosphere, followed by several<br />

sharp blows with the mallet to seat the<br />

prosthesis. The center screwdriver is<br />

then used again, this time to advance<br />

the recessed central screw firmly into<br />

the peg of the baseplate.<br />

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n RESULTS<br />

We recently performed a retrospective review of 45 reverse<br />

shoulder arthroplasty patients, with an average follow<br />

up of 42 months. 16 The indication for the procedure<br />

was end-stage glenohumeral arthritis with massive irreparable<br />

rotator cuff tear in 21 patients, revision of failed<br />

hemiarthroplasty in 19 patients, <strong>and</strong> fracture sequelae<br />

with severe malunion or nonunion of the tuberosities in<br />

5 patients. All 3 groups showed a significant increase<br />

in active elevation (from 55° pre-operatively to 121° postoperatively)<br />

<strong>and</strong> Constant Score 24 (from 17 to 59), but<br />

no significant change in active external rotation (from<br />

7° to 11°) or internal rotation (S1 pre <strong>and</strong> postoperatively).<br />

Seventy-eight percent of patients were satisfied or very<br />

satisfied with the result, <strong>and</strong> 67% of patients had no or<br />

slight pain. However, the postoperative Constant Score,<br />

adjusted Constant Score, <strong>and</strong> ASES <strong>Shoulder</strong> Score were<br />

all significantly higher in the CTA group as compared<br />

with the revision group (P = 0.01, 0.004, <strong>and</strong> 0.002,<br />

respectively). Severe fatty infiltration of the teres minor 25<br />

was associated with lower external rotation (0° vs. 15°,<br />

P = 0.02) <strong>and</strong> lower functional results (Constant score:<br />

46 vs. 66, P = 0.007).<br />

FIGURE 18. The trial insert is impacted into the trial humeral<br />

prosthesis, followed by a reduction to assess tension<br />

<strong>and</strong> stability.<br />

time. Activities as tolerated are allowed at 3 to 4 months<br />

postoperatively.<br />

Complications<br />

In our series of 45 patients, 14 complications occurred<br />

in 11 patients (24%). The most common complications<br />

were dislocation (3 cases), deep infection (3 cases), periprosthetic<br />

humeral fracture (2 cases), <strong>and</strong> late acromial<br />

fracture (2 cases). One case of postoperative hematoma,<br />

axillary nerve palsy, <strong>and</strong> symptomatic humeral loosening<br />

were also observed. Complication <strong>and</strong> revision rates<br />

were highest in the revision group (47% <strong>and</strong> 26%,<br />

respectively).<br />

Ten patients (22%) needed further surgery for treatment<br />

of a complication. All 3 dislocation patients (1 in<br />

the CTA group, 2 in the revision group) were brought<br />

back to the operating room for liner exchange or addition<br />

of the 9 mm metal spacer with retentive 6 mm liner. Two<br />

FIGURE 19. The final polyethylene<br />

insert is impacted into the humeral<br />

prosthesis.<br />

146 <strong>Technique</strong>s in <strong>Shoulder</strong> <strong>and</strong> Elbow Surgery


<strong>Reverse</strong> <strong>Shoulder</strong> <strong>Arthroplasty</strong><br />

FIGURE 20. Final radiographs. Note<br />

the slight inferior tilt of the glenosphere.<br />

patients in the revision group required prosthetic removal<br />

for infection. One infection in the revision group was<br />

treated successfully with 1-stage irrigation, debridement,<br />

<strong>and</strong> polyethylene liner exchange. One patient in the revision<br />

group developed aseptic humeral loosening. The<br />

humeral component was revised 1 year postoperatively.<br />

Another patient required revision for treatment of a periprosthetic<br />

humeral fracture sustained in a motor vehicle<br />

accident. Although no cases of glenoid loosening were<br />

observed, 1 patient required removal of the glenosphere<br />

on postoperative day number 1. The glenoid was fractured<br />

during reaming, but the metaglene <strong>and</strong> glenosphere<br />

appeared to be stable after implantation. The glenosphere<br />

was noted to lose fixation on postoperative radiographs,<br />

<strong>and</strong> the patient was brought back to the operating room<br />

for conversion to a humeral head replacement.<br />

Scapular notching, or loss of inferior glenoid bone<br />

secondary to impingement of the prosthesis against the<br />

inferior glenoid neck (Fig. 21), was observed on final<br />

radiographs in 24 cases (74%). Twenty-eight percent<br />

of patients exhibited scapular notching that extended<br />

beyond the inferior screw. Despite the high percentage<br />

of cases that exhibited scapular notching, none were<br />

symptomatic <strong>and</strong> no cases of glenoid loosening were noted.<br />

Heterotopic ossification was noted on postoperative<br />

radiographs in 17 cases (45%), always occurring at the<br />

lower margin of the glenoid. Grade I ossification 18<br />

was found in 11 cases, grade 2 in 2 cases, <strong>and</strong> grade<br />

III in 4 cases 26 . Grade III ossification cases tended to<br />

have greater restriction in range of motion (passive <strong>and</strong><br />

active) than patients with less severe heterotopic ossification.<br />

A bony spur at the inferior margin of the scapular<br />

neck was noted in 24 cases (63%) <strong>and</strong> was always associated<br />

with a scapular notch (Fig. 21).<br />

n FUTURE OF THE TECHNIQUE<br />

Our most pressing concern regarding this prosthesis is<br />

that it is used for the correct indications, as outlined above.<br />

The Tornier Aequalis <strong>Reverse</strong>d <strong>Shoulder</strong> ProsthesisÔ<br />

was designed based upon the principles of Paul Grammont,<br />

including a horizontal humeral neck cut, hemispherical<br />

glenoid component with secure locked screw fixation,<br />

<strong>and</strong> a medialized <strong>and</strong> lowered center of rotation<br />

that increases the effectiveness of the deltoid while minimizing<br />

glenoid loosening. The prosthesis is designed<br />

for individuals with end-stage glenohumeral arthritis<br />

with an extensive irreparable cuff deficiency. Although<br />

short <strong>and</strong> intermediate term data regarding the longevity<br />

of this prosthesis are quite favorable, long term data are<br />

FIGURE 21. ‘‘Notching’’ of the inferior glenoid by the<br />

medial humeral prosthetic neck. Note the hypertrophic<br />

osteophyte just medial to the notch.<br />

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147


Hatzidakis et al<br />

FIGURE 22. A, Anteroposterior radiograph of glenohumeral arthritis with extensive cuff deficiency in a patient with a ‘‘pseudoparalytic’’<br />

painful shoulder. Axial computerized tomography slice reveals rupture of the subscapularis <strong>and</strong> significant atrophy<br />

of the external rotators. B, Anteroposterior radiograph of the shoulder at maximum elevation. Postoperative radiograph<br />

of the patient’s reverse prosthesis, <strong>and</strong> her forward flexion 9 months postoperatively.<br />

not available. Therefore, at this time we favor restricting<br />

the use of this prosthesis to older individuals. The major<br />

benefit of this prosthesis is that shoulder level function<br />

<strong>and</strong> above can reliably be achieved in patients with uncomplicated<br />

rotator cuff deficient arthritis (Fig. 22). This<br />

consistency of results has not been achieved in our or<br />

others’ h<strong>and</strong>s with the use of conventional hemiarthroplasty.<br />

Although the prosthesis offers some hope of pain<br />

relief <strong>and</strong> restoration of function in patients who require<br />

revision of failed shoulder prosthesis, complication rates<br />

are high (approximately 50%). Dislocation rates may be<br />

decreased by the availability of multiple length options<br />

for the humeral polyethylene insert <strong>and</strong> with use of the<br />

larger component. We anticipate that this prosthetic design<br />

will continue to be a valuable tool in treating patients<br />

for whom satisfactory options have often been<br />

lacking in the past.<br />

n REFERENCES<br />

1. Cofield RH. Total shoulder arthroplasty with the Neer<br />

prosthesis. J Bone Joint Surg Am. 1984;66-A:899–906.<br />

2. Field LD, Dines DM, Zabinski SJ, et al. Hemiarthroplasty<br />

of the shoulder for rotator cuff arthropathy. J <strong>Shoulder</strong><br />

Elbow Surg. 1997;6:18–23.<br />

148 <strong>Technique</strong>s in <strong>Shoulder</strong> <strong>and</strong> Elbow Surgery


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3. Neer CS, Watson KC, Stanton FJ. Recent experience in<br />

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4. Neer CS, Craig EV, Fukuda H. Cuff-tear arthropathy.<br />

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9. Franklin JL, Barrett WP, Jackins SE, et al. Glenoid loosening<br />

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cuff deficiency. J <strong>Arthroplasty</strong>. 1988;3:39–46.<br />

10. Broström LÅ, Wallenstein R, Olsson E, et al. The Kessel<br />

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Clin Orthop. 1992;277:155–160.<br />

11. Gross RM. History of total shoulder arthroplasty. In: Crosby<br />

L., ed. Total <strong>Shoulder</strong> <strong>Arthroplasty</strong>. Rosemont Il: American<br />

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12. Grammont P, Trouilloud P, Laffay JP, et al. Etude et réalisation<br />

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13. Grammont PM, Baulot E. Delta shoulder prosthesis for<br />

rotator cuff rupture. Orthopedics. 1993;16:65–68.<br />

14. Grammont PM, Baulot E, Chabernaud D. R ésultats des 16<br />

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ciment pour des omarthroses avec gr<strong>and</strong>e rupture de coiffe.<br />

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15. Baulot E, Chabernaud D, Grammont P. R ésultats de la<br />

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de 16 cas. Acta Orthop Belg. 1995;61(Suppl I):112–<br />

119.<br />

16. Boileau P, Watkinson D, Hatzidakis A, et al. The Grammont<br />

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18. DeWilde L, Mombert M, Van Petegem P, et al. Revision of<br />

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(Delta III). Report of five cases. Acta Orthop Belg.<br />

2001;67:348–353.<br />

19. Favard L, Lautmann S, Sirveaux F, et al. Hemi arthroplasty<br />

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Molé D, eds. 2000 <strong>Shoulder</strong> Prosthesis . Two to Ten Year<br />

Follow-Up. Montpellier France: Sauramps Medical; 2001:<br />

261–268.<br />

20. Jacobs R, DeBeer P, De Smet L. Treatment of rotator cuff<br />

arthropathy with a reversed delta shoulder prosthesis. Acta<br />

Orthop Belg. 2001;67:344–347.<br />

21. Sirveaux F, Favard L, Oudet D, et al. Grammont inverted<br />

total shoulder arthroplasty in the treatment of glenohumeral<br />

osteoarthritis with massive <strong>and</strong> non repairable cuff rupture.<br />

In: Walch G, Boileau P, Molé D, eds. 2000 <strong>Shoulder</strong><br />

Prosthesis . Two to Ten Year Follow-Up. Montpellier<br />

France: Sauramps Medical; 2001:247–252.<br />

22. Valenti Ph, Boutens D, Nerot C. Delta 3 reversed prosthesis<br />

for arthritis with massive rotator cuff tear: long term results<br />

(.5 years). In: Walch G, Boileau P, Molé D, eds. 2000<br />

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France: Sauramps Medical; 2001:253–259.<br />

23. Boileau P, Trojani C, Walch G, et al. <strong>Shoulder</strong> arthroplasty<br />

for the treatment of the sequelae of fractures of the proximal<br />

humerus. J <strong>Shoulder</strong> Elbow Surg. 2001;10:299–308.<br />

24. Constant CR, Murley AHG. A. Clinical method of functional<br />

assessment of the shoulder. Clin Orthop. 1987;<br />

214:160–164.<br />

25. Goutallier D, Postel JM, Bernageau J, et al. Fatty muscle<br />

degeneration in cuff ruptures. Pre- <strong>and</strong> postoperative evaluation<br />

by CT scan. Clin Orthop. 1994;304:78–83.<br />

26. Kjaersgaard-Andersen P, Frich LH, Sojbjerg JO, et al.<br />

Heterotopic bone formation following total shoulder<br />

arthroplasty. J <strong>Arthroplasty</strong>. 1989;4:99–104.<br />

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