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Diapositive 1 - WorldPharma 2010

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Method<br />

● Inclusion criteria<br />

◦ Exposure to tramadol during embryogenesis (weeks 4 to 12 after LMP)<br />

◦ Only pure prospective cases with data collected before week 22, i.e<br />

before the level II US.<br />

● Data collection was performed by phone or mail<br />

◦ At the time of request for risk evaluation.<br />

◦ Within 2-3 months after the expected date of delivery.<br />

● Control group:<br />

Healthy women counseled after a non-teratogenic exposure.<br />

● Data collected from 1997 to 2009

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