Stem Cell Mobilization - CBMTG
Stem Cell Mobilization - CBMTG
Stem Cell Mobilization - CBMTG
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Strategy 3 : Plerixafor decision based on actual<br />
mobilization of CD34+ cells after 4 days of G-CSF<br />
Advantages<br />
Disadvantages<br />
Reduced need for<br />
remobilization<br />
Lower number of apheresis<br />
sessions<br />
High rate of plerixafor utilization<br />
(~40-70%)<br />
Need for stat CD34+ count<br />
Avoid unnecessary use of<br />
plerixafor in patients with<br />
adequate G-CSF mobilization<br />
Lower growth-factor,<br />
apheresis and<br />
cryopreservation costs<br />
Improved transplant center<br />
“flow” (predictability)<br />
10
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