PD Dr. med. Holger HÃ¤nÃle

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Haenssle H.A., Krueger U., Vente C., Thoms KM., Bertsch HP., Zutt M., Rosenberger A., Neumann C., Emmert S.: Results from an observational trial: digital epiluminescence microscopy follow-up of atypical nevi increases the sensitivity and the chance of success of conventional dermoscopy in detecting melanoma. Journal of Investigative Dermatology, 2006; 126(5):980-5. Haenssle H.A., Vente C., Bertsch H.P., Rupprecht R., Abuzahra F., Junghans V., Ellinghaus B., Emmert S., Hallermann C., Neumann Ch.: Results of a surveillance programme for patients at high risk for malignant melanoma using digital and conventional dermoscopy. European Journal for Cancer Prevention, 2004; 13(2):133-8. (Immun-)Therapie des malignen Melanoms Haenssle H.A., Riedl P., Buhl T., Schardt A., Rosenberger A., Schön M.P., Schirmbeck R.: Intracellular delivery of MHC class I-binding epitopes: Dendritic cells loaded and matured with cationic peptide/poly(I:C) complexes efficiently activate T cells. Experimental Dermatology, 2010; 19(1):19- 28. Knudsen S., Schardt A., Buhl T., Boeckmann L., Schön M.P., Neumann C., Haenssle H.A.: Enhanced T-cell activation by immature dendritic cells loaded with HSP70-expressing heat-killed melanoma cells. Experimental Dermatology, 2010; 19(2):108-16. Haenssle H.A., Buhl T., Knudsen S., Krueger U., Reich K., Neumann C.: CD40 ligation during dendritic cell maturation reduces cell death and prevents interleukin-10-induced regression to macrophagelike monocytes. Experimental Dermatology, 2008; 17(3):177-87. Kretschmer L., Thoms K.M., Peeters S., Haenssle H.A., Bertsch H.P., Emmert S.: Postoperative morbidity of lymph node excision for cutaneous melanoma-sentinel lymphonodectomy versus complete regional lymphnode dissection. Melanoma Research, 2008; 18(1):16-21. Haenssle H.A.: Vaccination therapy with tumor-dendritic cell hybrids: a promising therapeutic approach? Current Opinion in Investigational <strong>Dr</strong>ugs, 2005; 6(12): 1240-5. Review. Kretschmer L., Beckmann I., Thoms K.M., Haenssle H.A., Bertsch H.P., Neumann Ch.: Sentinel lymphonodectomy does not increase the risk of loco-regional cutaneous metastases of malignant melanomas. European Journal of Cancer, 2005; 41(4):531-8. Haenssle H.A., Emmert S., Krause S.W., Zutt M., Kretschmer L., Schmidberger H., Andreesen R., Soruri A.: Hybrid cell vaccination in metastatic melanoma: Results of a phase I/II study. Journal of Immunotherapy, 2004; 27(2):147-55. Emmert S., Zutt M., Haenssle H.A., Neumann C., Kretschmer L.: Inefficacy of vindesine monotherapy in advanced stage IV malignant melanoma patients previously treated with other chemotherapeutic agents. Melanoma Research, 2003; 13(3):299-302. Genodermatosen (Verhornungsstörungen) Haenssle H.A., Finkenrath A., Hausser I., Oji V., Traupe H., Hennies HC., Neumann C., Emmert S.: Effective treatment of severe thermodysregulation by oral retinoids in a patient with recessive congenital lamellar ichthyosis. Clinical and Experimental Dermatology, 2008; 33(5):578-81. Emmert S., Küster W., Hennies HC., Zutt M., Haenssle H.A., Kretschmer L., and Neumann C.: 47 patients in 14 families with the rare genodermatosis keratosis punctata palmoplantaris Buschke- Fischer-Brauer. European Journal of Dermatology, 2003; 13:16-20. Emmert S., Küster W., Zutt M., Hänssle H.A., Hallermann C., Kretschmer L., and Neumann C.: A new family with the rare genodermatosis keratosis punctata palmo-plantaris Buschke-Fischer-Brauer. Journal of the American Academy of Dermatology, 2003; 49:1166-1169.
<strong>Holger</strong> Haenssle, MD Clinical spectrum: General Dermatology (outpatient clinic) Outpatient Surgery Pigmented Lesion Clinic (dermatoscopy) Dermatooncology Clinic and Tumor Follow-up Clinic Ultrasound examination of skin/subcutaneous tissue Phlebology Laser Surgery Clinic Scientific profile: Early detection of melanoma and (digital) Dermatoscopy (Immuno-)Therapy of metastasized melanoma Diagnostic use of Ultrasound Genodermatoses Funding: Niedersächsische Krebsgesellschaft, Bundesministerium für Wirtschaft und Technologie (ZIM-Project), Industry Selected Publications: Early detection of melanoma and (digital) Dermatoscopy Haenssle H.A., Richter A., Buhl T., Haas E., Holzkamp R., Emmert S., Schön M.P.: Pigmented basal cell carcinomas 15 years after orbital radiation therapy for Graves ophthalmopathy. Archives of Dermatology, 2011; 147(4):511-2. Buhl T., Haenssle H.A.: Symmetrically enlarging pigmented lesion in an adolescent. Hautarzt, 2011; 62(8):625-6. Buhl T., Hansen-Hagge C., Korpas B., Kaune K.M., Haas E., Rosenberger A., Schön M.P., Emmert S., Haenssle H.A.: Integrating static and dynamic features of melanoma: The DynaMel algorithm. Journal of the American Academy of Dermatology, 2011 Jun 7. [Epub ahead of print] Haenssle H.A., Korpas B., Hansen-Hagge C., Buhl T., Kaune K.M., Johnsen S., Rosenberger A., Schön M.P., Emmert S.: Selection of patients for long-term surveillance with digital dermoscopy by assessment of melanoma risk factors. Archives of Dermatology, 2010; 146(3):257-64. Haenssle H.A., Korpas B., Hansen-Hagge C., Buhl T., Kaune K.M., Rosenberger A., Krueger U., Schön M.P., Emmert S.: Seven-point checklist for dermatoscopy: performance during 10 years of prospective surveillance of patients at increased melanoma risk. Journal of the American Academy of Dermatology, 2010; 62(5):785-93. Haenssle H.A., Kaune K.M., Buhl T., Thoms K.M., Padeken M., Emmert S., Schön M.P.: Melanoma arising in segmental nevus spilus: detection by sequential digital dermatoscopy. Journal of the American Academy of Dermatology, 2009; 61(2):337-41. Haenssle H.A., Kaune K.M., Buhl T., Thoms KM., Padeken M., Mitteldorf C., Emmert S.: Large speckled lentiginous nevus superimposed with Spitz nevi: Sequential digital dermoscopy may lead to unnecessary excisions triggered by dynamic changes. Clinical and Experimental Dermatology, 2009; 34(2):212-5. Haenssle H.A.: Strategien zur klinischen Früherkennung des malignen Melanoms -Gegenwart und Zukunft. TumorDiagnostik und Therapie, 2009; Ausg. 6, Jahrg. 30: 302-306. Haenssle H.A.: Melanomfrüherkennung durch sequentielle digitale Dermatoskopie, Dermatologie, 2009; 35:75–78. Aktuelle Haenssle H.A.: Blickdiagnostik: Pigmentmale, Via Medici, Heft 03/2007:62-64
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