Dr Nitin Saksena - Westmead Millennium Institute

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Lau KA, Bin Wang, Monica Miranda-Saksena, Ross Boadle, Adeeba Kamarulzaman, Kee-Peng Ng and Nitin K. Saksena. Evidence for possible biological advantages of the newly emerging HIV-1 circulating recombinant form (CRF) from Malaysia - CRF33_01B in comparison to its progenitors- CRF01_AE and subtype B. In Press- Current HIV Research, USA. 1, 8(3): 159-171; 2010. [Abstract] Wightman F, Ajantha Solomon, Gabriela Khoury, Justin Green, Lachlan Gray, Paul R Gorry, Nitin K. Saksena, Yung Shwen Ho, Jennifer Hoy, Suzanne M Crowe, Paul U Cameron Sharon R Lewin. Both CD31-positive and CD31-negative naive CD4 T-cells are persistent HIV-infected reservoirs in individuals receiving antiretroviral therapy. Journal of Infectious Diseases (In Press) 2010. [Abstract] Zhou L, Eve Diefenbach, Ben Crossett, Rejane Rua, Bin Wang, Amit Kapur, Bruce J. Brew and Nitin K. Saksena. First evidence of overlaps between HIV-Associated Dementia (HAD) and nonviral neurodegenerative diseases: Proteomic analysis of the frontal cortex from HIV+ patients with and without dementia. Molecular Neurodegeneration (In Press) 2010. [Abstract] Zhou L, Rua R, Ng T, Vongrad V, Ho YS, Geczy C, Hsu K, Brew BJ, Saksena NK.Evidence for predilection of macrophage infiltration patterns in the deeper midline and mesial temporal structures of the brain uniquely in patients with HIV-associated dementia. BMC Infectious Diseases;9:192. 2010. [Abstract] Wade J, Sterjovski J, Gray L, Roche M, Chiavaroli L, Ellett A, Jakobsen MR, Cowley D, Pereira Cda F, Saksena N, Wang B, Purcell DF, Karlsson I, Fenyö EM, Churchill M, Gorry PR. Enhanced CD4+ cellular apoptosis by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with progressive HIV-1 infection. Virology. 2010 Jan 20;396(2):246-55. Wang B, Dwyer DE, Blyth CC, Soedjono M, Shi H, Kesson A, Ratnamohan M, McPhie K, Cunningham AL, Saksena NK Detection of the rapid emergence of the H275Y mutation associated with oseltamivir resistance in severe pandemic influenza virus A/H1N1 09 infections. Antiviral Res. 2010 Jul;87(1):16-21. Epub 2010 Apr 10. [Abstract] Yoo, P., Shwen Ho, Y., Ng, J., Charleston, M., Saksena, N., Yang, P., Zomaya, A. (2010), Hierarchical kernel mixture models for the prediction of AIDS disease progression using HIV structural gp120 profiles. BMC Genomics. 11, S22. [Abstract] 2009 Gray, L., M. Roche, M. J. Churchill, J. Sterjovski, A. Ellett, P. Poumbourios, S. Sherieff, B. Wang, N. Saksena, D. F. Purcell, S. Wesselingh, A. L. Cunningham, B. J. Brew, D. Gabuzda and P. R. Gorry. "Tissue-specific sequence alterations in the human immunodeficiency virus type 1 envelope favoring CCR5 usage contribute to persistence of dual-tropic virus in the brain." J Virol 83(11): 5430-5441.2009. Saksena, N., J. Q. Wu, K. A. Lau, L. Zhou, M. Soedjono and B. Wang. CD8 Antiviral Soluble Factors and Human Immunodefieciency Virus (HIV) Control. M. A. Ph.D, Bentham Books (Bentam Science Publishers): 11-34. 2009. Westmead Millennium Institute
Steain, M. C., D. E. Dwyer, A. C. Hurt, C. Kol, N. K. Saksena, A. L. Cunningham and B. Wang (2009). "Detection of influenza A H1N1 and H3N2 mutations conferring resistance to oseltamivir using rolling circle amplification." Antiviral Res 84(3): 242-248. [Abstract] van Hal, S. J., B. Herring, Z. Deris, B. Wang, N. K. Saksena and D. E. Dwyer (2009). "HIV-1 integrase polymorphisms are associated with prior antiretroviral drug exposure." Retrovirology 6: 12. [Abstract] Wang, B., D. E. Dwyer, C. B. Chew, C. Kol, Z. P. He, H. Joshi, M. C. Steain, A. L. Cunningham and N. K. Saksena (2009). "Sensitive detection of the K103N non-nucleoside reverse transcriptase inhibitor resistance mutation in treatment-naive HIV-1 infected individuals by rolling circle amplification." J Virol Methods 161(1): 128-135. 2008 Wu JQ, Wang B, Saksena NK. Transitory viremic surges in an HIV+ elite controller can shift cellular transcriptome profile: a word of caution for microarray studies. J Virol. 2008 Aug 13. [Epub ahead of print] PMID: 18701597. [Abstract] Wu JQ, Dwyer DE, Dyer WB, Yang YH, Wang B, Saksena NK. Transcriptional profiles in CD8+ T cells from HIV+ progressors on HAART are characterized by coordinated up-regulation of oxidative phosphorylation enzymes and interferon responses. Virology. 2008Aug 8. [Epub ahead of print] PMID: 18692859. [Abstract] Caly L, Saksena NK, Piller SC, Jans DA. Impaired nuclear import and viral incorporation of Vpr derived from a HIV long-term non-progressor. Retrovirology. 2008 Jul 18;5:67. [Abstract] Zhou L, Ng T, Yuksel A, Wang B, Dwyer DE and Saksena NK: Absence of HIV infection in the choroid plexus of two patients who died rapidly with HIV-associated dementia. AIDS Research & Human Retroviruses, 24(6): 839-843. 2008. [Abstract] Lau KA Bin Wang, Adeeba Kamarulzaman, Kee-Peng Ng and Nitin K. Saksena. Continuous crossover(s) events of HIV-1 CRF01_AE and B subtype strains in Malaysia: Evidence of Rapid and Extensive HIV-1 Evolution in the Region. Current HIV Research, 6(2) 108-16; 2008. [Abstract] Fujii YR and Saksena NK:”RNA and the Regulation of Gene Expression” (Book Chapter) in “RNA and the Regulation of Gene Expression: A Hidden Layer of Complexity”, Publisher: Horizon Scientific Press; Editor: Kevin V. Morris, The Scripps Research Institute, 10550 N. Terrey Pines Road, La Jolla, CA, 92037. 2008 (In press, January 1, 2008). ISBN 1904455255, 9781904455257; 228 pages. Saksena NK, Wu JQ, Potter SJ, Wilkinson J and Wang B. HIV interaction with the CD8+ T cells. Current HIV Research (Peer Reviewed) 6(1); 1-9: 2008. [Abstract] Ho YS, Abecasis AB, Theys K, Deforche K, Dwyer DE, Charleston M, Vandamme AM, Saksena NK.HIV-1 gp120 N-linked glycosylation differs between plasma and leukocyte compartments. Virol J. 2008 Jan 23;5(1):14 [Epub ahead of print]. Steain MC, Wang B and Saksena NK. The possible contribution of HIV-induced syncytia to the generation of intersubtype recombinants in vitro. AIDS, 22(9)1009-17; 2008). [Abstract] Westmead Millennium Institute
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Dr Nitin Saksena - Westmead Millennium Institute

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