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Programme (PDF) - (NCRI) Cancer Conference 2013 - National ...

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High throughput sequencing and cancer genomes<br />

Hosted by Andy Futreal<br />

Wellcome Trust Sanger Institute, Hinxton, UK<br />

o Andy Futreal<br />

Wellcome Trust Sanger Institute, Hinxton, UK<br />

Introduction<br />

o Andy Futreal<br />

Wellcome Trust Sanger Institute, Hinxton, UK<br />

Title to be confirmed<br />

o Bruno Clement<br />

Institut national de la santé et de la recherche médicale (INSERM), France<br />

Hepatocellular cancer and genomes<br />

o Stacey Gabriel<br />

Broad Institute, Massachusetts Institute of Technology, Cambridge, USA<br />

Comprehensive cancer genome characterisation by sequencing<br />

Proffered paper presentations:<br />

o Tarek Abdel-Fatah<br />

School of Molecular Medical Sciences and Nottingham University Hospital<br />

Trust, University of Nottingham, UK<br />

High resolution array Comparative Genomic Hybridization (aCGH)<br />

of breast carcinoma identifies Mouse Double Minutes 4 (Mdm4)<br />

as one of the early genetic changes in breast cancer<br />

development: Mdm4 is a new independent prognostic and<br />

predictive marker<br />

o Salwati Shuib<br />

School Department of Medical and Molecular Genetics, University of<br />

Birmingham, UK<br />

Analysis of copy number alterations in familial and sporadic<br />

clear cell renal cell carcinoma with high resolution SNP arrays<br />

o Juliet Kenicer<br />

Edinburgh <strong>Cancer</strong> Research Centre, the University of Edinburgh, UK<br />

A transcriptomic and genomic investigation into taxane<br />

resistant breast cancer<br />

Proffered paper highlights 2<br />

Host to be confirmed<br />

o Zuzana Bencokova<br />

CR-UK/MRC Gray Institute for Radiation Oncology and Biology, University of<br />

Oxford, UK<br />

Sensitisation of hypoxic tumour cells through inhibition of PARP is<br />

oxygen dependent and correlates with decreased homologous<br />

recombination<br />

o<br />

Debbie Cunningham<br />

University of Birmingham, UK<br />

Differential phosphoproteomics of fibroblast growth factor<br />

signalling: identification of Src-mediated phosphorylation events<br />

o Patricia Muller<br />

The Beatson institute for <strong>Cancer</strong> Research, Glasgow, UK<br />

Mutant p53 regulates invasion via integrins and EGFR<br />

o Gareth Inman<br />

The Beatson Institute for <strong>Cancer</strong> Research , Glasgow, UK<br />

Downregulation of Disabled-2 switches TGF-beta from a<br />

tumour suppressor to a tumour promoter<br />

22

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