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Best Design of BE Studies (7) - BEBAC • Consultancy Services for ...

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7/7 | Statistical <strong>Design</strong> and Analysis IIII<br />

Dose Proportionality<br />

Two-step procedure<br />

Model 1 indicates that the relation between<br />

response and dose is linear.<br />

The dose response curve is a straight line, which<br />

passes through the origin.<br />

This model is commonly referred to as<br />

dose proportionality.<br />

in<strong>for</strong>ma<br />

life sciences<br />

Bioequivalence and Bioavailability, Pre-conference workshop | Budapest, 11 May 2009 4 • 19

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