Disclosures

Facts about Gram (-) NP
• Ps.aeruginosa is the most common organism
24%, associated with a mortality of ~50%
• Other emerging organisms resistant to Rx
include: Acinetobacter spp. KPC, NDM-1, VIM’s,
AMP-C Enterobacter, Klebsiella, E.coli etc’ ,
Stenotrophomonas sp.
• Therapy options for these organisms:
carbapenems (include. doripenem), colistinpolymyxin,
amikacin, intra-tracheal amikacin,
colistin,levofloxacin and aztreonam