tRANSPORtERS - Molecular Devices

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TOPICS OF THE PRESENTATION Overview about AXXAM Overview about Transporters FLIPR based assays for a. GABA Transporters Conclusions b. Glycine Transporters
AXXAM AXXAM s.r.l. was founded at the 22nd of May 2001 at Milano AXXAM is located at the San Raffaele Science Park in Milano (Italy) and has more than 1400 square metres of fully equipped lab space The team consists of 45 people At the 8th of November 2001 a five years collaboration agreement (worth of 30 Million Euros) between BAYER AG and AXXAM was signed
Page 1: FLIPR based assays for electrogenic
Page 5 and 6: Transporters Transporters are invo
Page 7 and 8: GABA transporter family (Na/Cl depe
Page 9 and 10: GABA TRANSPORTERS • belongs to th
Page 11 and 12: Patch clamp analysis of GABA-induce
Page 13 and 14: Membrane potential vs fluorescence
Page 15 and 16: HEK-293/hGAT-3 EC 50 DETERMINATION
Page 17 and 18: Patch clamp: GABA-induced current i
Page 19 and 20: HEK-293/rGAT-1 EC 50 DETERMINATION
Page 21 and 22: Glycine Transporters Glycine Trans
Page 23 and 24: Voltage sensitive dye-FLIPR Glycine
Page 25 and 26: Voltage sensitive dye-FLIPR Glycine
Page 27 and 28: Summary Voltage sensitive dye and

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