tRANSPORtERS - Molecular Devices

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Transporter families ion transporters & pumps - sodium-potassium ATPase - Organic Anion transporters (OATS) - Na/Ca exchangers metabolite transporters - Amino acids -Glucose - Lactate neurotrasmitter transporters - Vescicular -Plasma membrane
GABA transporter family (Na/Cl dependent) HUGO PRODUCT Substrate (preferred) coupling Locus (human) SLC6A1 GAT-1 -aminobutiric acid Na + /Cl - 3p25-p24 SLC6A2 NAT1/NET1 norepinephrine Na + /Cl - 16q12.2 SLC6A3 DAT1 dopamine Na + /Cl - 5p15.3 SLC6A4 HTT serotonin Na + /Cl - 17q11.1-q12 SLC6A5 GLYT-2 L-glycin Na + /Cl - 11p15.1-15.2 SLC6A6 TAUT taurin Na + /Cl - 3p26-p24 SLC6A6P pseudogene 21pter-qter SLC6A7 prot L-proline Na + /Cl - 5q31-q32 SLC6A8 CT1/CRTR creatine Na + /Cl - Xq28 SLC6A9 GLYT-1a to 1c L-glycin Na + /Cl - 1p33 SLC6A10 CT-2 creatine Na + /Cl - 16p11.2 SLC6A11 GAT-3 -aminobutiric acid Na + /Cl - reserved SLC6A12 BGT-1 -aminobutiric acid, Na + /Cl - 12p13 betaine SLC6A13 GAT-2 -aminobutiric acid Na + /Cl - 12p13.3 SLC6A14 hATB(0+ neutral, cationic amino acids Na + /Cl - Xq23-q24 SLC6A15 hv7-3/homology reserved SLC6A16 homology reserved
Page 1 and 2: FLIPR based assays for electrogenic
Page 3 and 4: AXXAM AXXAM s.r.l. was founded at
Page 5: Transporters Transporters are invo
Page 9 and 10: GABA TRANSPORTERS • belongs to th
Page 11 and 12: Patch clamp analysis of GABA-induce
Page 13 and 14: Membrane potential vs fluorescence
Page 15 and 16: HEK-293/hGAT-3 EC 50 DETERMINATION
Page 17 and 18: Patch clamp: GABA-induced current i
Page 19 and 20: HEK-293/rGAT-1 EC 50 DETERMINATION
Page 21 and 22: Glycine Transporters Glycine Trans
Page 23 and 24: Voltage sensitive dye-FLIPR Glycine
Page 25 and 26: Voltage sensitive dye-FLIPR Glycine
Page 27 and 28: Summary Voltage sensitive dye and

tRANSPORtERS - Molecular Devices

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