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Course syllabus and schedule - Academic Resources at Missouri ...

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BIO 251<br />

Fall 2010 / Walton<br />

BIO 251: Medical <strong>and</strong> Public Health Microbiology<br />

SYLLABUS<br />

General course inform<strong>at</strong>ion:<br />

Instructor: Dr. Kristen Walton<br />

Office: #13 Modular 7 (trailers north of Remington Hall)<br />

Phone: 816-271-5613<br />

Email: kwalton1@missouriwestern.edu<br />

Office hours: MW 12:00-1:30pm, TR 12:00pm-1:00pm, or by appointment<br />

Required books <strong>and</strong> m<strong>at</strong>erials:<br />

Alcamo’s Fundamentals of Microbiology, Body Systems Ed., by Jeffrey C.<br />

Pommerville, ISBN# 9780763762599 (an electronic version of this<br />

textbook is available from the publisher)<br />

Symbiosis Custom Labor<strong>at</strong>ory Manual for BIO 251, Benjamin Cummings<br />

(available <strong>at</strong> the MWSU bookstore)<br />

CPS clicker by EInstruction (ISBN: 9781881483717; older models not acceptable) <strong>and</strong> access<br />

code (purchase <strong>at</strong> the bookstore or online <strong>at</strong> http://www.einstruction.com). The class key to<br />

enroll your clicker in BIO 251 is: F62460E666<br />

Primary course website: http://webct.missouriwestern.edu<br />

Basic course inform<strong>at</strong>ion: http://academic.missouriwestern.edu/kwalton1/BIO_251.htm<br />

Publisher’s website with study tools: http://microbiology.jbpub.com/bodysystems/<br />

<strong>Course</strong> objectives:<br />

This course will explore microbiology in the context of human infectious disease. After successfully completing this<br />

course, students will be able to:<br />

Describe <strong>and</strong> compare characteristics of major classes of microbes<br />

Explain mechanisms of action for various microbial control agents<br />

Explain how the human immune system responds to infectious agents<br />

Discuss characteristics <strong>and</strong> disease-causing mechanisms of selected microbial p<strong>at</strong>hogens<br />

Analyze case studies <strong>and</strong> d<strong>at</strong>a rel<strong>at</strong>ed to microbes <strong>and</strong> infectious disease<br />

Use st<strong>and</strong>ard microbiological labor<strong>at</strong>ory techniques to identify <strong>and</strong> characterize specific microbes<br />

Classroom environment <strong>and</strong> behavior:<br />

The classroom is a professional environment, <strong>and</strong> students are expected to act accordingly. See p28 of the<br />

Student H<strong>and</strong>book (http://www.missouriwestern.edu/h<strong>and</strong>book/index.pdf ) for the University policy on<br />

Classroom Behavior.<br />

The use of any personal electronic devices (cell phones, iPods, etc) is prohibited during class time. These devices<br />

must be turned off or set to silent mode <strong>and</strong> put away during class. This includes text messaging. Laptops or<br />

iPads are allowed provided the student is using the laptop solely for note-taking.<br />

You are expected to particip<strong>at</strong>e in discussions <strong>and</strong> group work, to be <strong>at</strong>tentive while someone else is speaking, <strong>and</strong><br />

to show respect for the comments <strong>and</strong> questions of others.<br />

Failure to comply with these policies or to follow lab safety procedures may result in loss of any points earned<br />

th<strong>at</strong> day, an unexcused absence, <strong>and</strong>/or dismissal from class.<br />

Attendance policies:<br />

Attendance in lecture will be recorded using your CPS clicker. Therefore, you must bring it to every lecture.<br />

If you do not have your clicker, or you are l<strong>at</strong>e to class, you are responsible for signing in with the instructor <strong>at</strong><br />

the end of class, or you will be considered absent. In-class quizzes may be taken using your clicker. If you do not<br />

have your clicker, b<strong>at</strong>teries, etc., you may receive a zero on the quiz.


BIO 251 2<br />

In order to improve student learning as well as to achieve compliance with federal financial aid policies, Western<br />

has a m<strong>and</strong><strong>at</strong>ory <strong>at</strong>tendance policy for all 100 <strong>and</strong> 200 level courses. The University <strong>at</strong>tendance policy is detailed<br />

on p22 of the Western <strong>Course</strong> C<strong>at</strong>alog (http://www.missouriwestern.edu/c<strong>at</strong>alog/academicpolicies.pdf ).<br />

Attendance is expected in both lecture <strong>and</strong> lab. You will be given an excused absence when acting as an official<br />

represent<strong>at</strong>ive of the university, provided you give prior written verific<strong>at</strong>ion from the faculty/staff supervisor<br />

of the event. Documented medical or family emergencies may also be considered excused absences. All other<br />

absences will be deemed unexcused. Excused absences must be requested no l<strong>at</strong>er than the first class<br />

following your absence.<br />

The maximum number of unexcused absences allowed for this class before the midterm report, October 27, is 5<br />

for lecture or 3 for lab. Thus, if you reach 6 unexcused lecture absences or 4 unexcused lab absences before<br />

October 27, you will be reported to the Registrar’s Office <strong>and</strong> will be autom<strong>at</strong>ically withdrawn from this class.<br />

The Financial Aid Office will reduce financial aid as appropri<strong>at</strong>e.<br />

Attendance in lab is especially important because lab skills often build on each other, <strong>and</strong> there are no makeup<br />

labs. Therefore, missing lab any time throughout the semester has further consequences. Two unexcused<br />

absences from lab by the last lab class meeting will result in a 10% reduction in your lab average, 3 unexcused<br />

absences from lab will result in a 20% reduction, <strong>and</strong> 4 or more unexcused lab absences will result in incomplete<br />

lab performance <strong>and</strong> a grade of F for the course. If you miss a lab for any reason, you are responsible for<br />

c<strong>at</strong>ching up on missed m<strong>at</strong>erial <strong>and</strong> completing assigned lab questions.<br />

There are no make-ups for in-class assignments <strong>and</strong> quizzes, regardless of the reason for an absence. If you<br />

know ahead of time th<strong>at</strong> you must miss a class in which an assignment is due, make arrangements to turn it in<br />

ahead of time. L<strong>at</strong>e assignments due to unexcused absences will not be accepted. Internet or WebCT problems<br />

are not acceptable excuses for l<strong>at</strong>e online assignments.<br />

Make-up exams will only be offered if an MWSU-approved reason exists (extreme illness, emergency, official<br />

MWSU business) <strong>and</strong> you take the initi<strong>at</strong>ive to contact me prior to the exam. Any make-up exams may be in a<br />

form<strong>at</strong> typically less preferred by students (such as essay).<br />

Disabilities:<br />

Any student requiring accommod<strong>at</strong>ion to perform successfully in the course should see me within the first week of class<br />

<strong>and</strong> arrangements will be made as necessary. Students requesting accommod<strong>at</strong>ions for assessments (exams, etc.) must<br />

have document<strong>at</strong>ion from the MWSU Office of Disability Services (phone 271-4330).<br />

Grading policies:<br />

Mastery of course content <strong>and</strong> objectives will be assessed by exams, assignments <strong>and</strong> quizzes, lab exercises <strong>and</strong> analysis<br />

of unknown bacteria, <strong>and</strong> a group project. Your lowest individual lecture quiz/assignment score will be dropped when<br />

your final course grade is calcul<strong>at</strong>ed <strong>at</strong> the end of the semester. No lab grades will be dropped. Your course grade will<br />

be calcul<strong>at</strong>ed based on the number of points you earn out of the total number of points possible for the course according<br />

to the scale below. You must pass the lab portion of the course to earn a passing grade for the course.<br />

Lecture (490-590 pts) Regular lecture exams 3 x 100 points = 300 pts<br />

Final exam 100<br />

Lecture quizzes/assignments 50-150<br />

Group project present<strong>at</strong>ion 40<br />

Lab (300-330 pts) Lab exams 2 x 100 points = 200<br />

Lab exercises (5 r<strong>and</strong>omly selected) 5 x 10 points = 50<br />

Lab quizzes 0-30<br />

Gram stain unknown 10<br />

Bacterial unknown 40<br />

Grading scale: 90-100% of total points = A; 80-89% = B; 70-79% = C; 60-69% = D; below 60% = F


BIO 251 3<br />

<strong>Academic</strong> Honesty Policy <strong>and</strong> Due Process Procedures:<br />

<strong>Academic</strong> honesty is required in all academic endeavors. Viol<strong>at</strong>ions of academic honesty include any instance of plagiarism,<br />

che<strong>at</strong>ing, seeking credit for another’s work, falsifying documents or academic records, or any other fraudulent activity.<br />

Viol<strong>at</strong>ions of academic honesty may result in a failing grade on the assignment, failure in the course, or expulsion from<br />

the University. When a student’s grade has been affected, viol<strong>at</strong>ions of academic honesty will be reported to the Provost<br />

or design<strong>at</strong>ed represent<strong>at</strong>ive on the <strong>Academic</strong> Honesty Viol<strong>at</strong>ion Report forms. Please see p26 of the Student H<strong>and</strong>book<br />

for specific activities identified as viol<strong>at</strong>ions of this policy <strong>and</strong> for the student due process procedure. This h<strong>and</strong>book is<br />

available online <strong>at</strong> http://www.missouriwestern.edu/h<strong>and</strong>book/index.pdf .<br />

Viol<strong>at</strong>ions of academic honesty include, but are not limited to, the following activities:<br />

1. Copying another person’s work <strong>and</strong> claiming it as your own;<br />

2. Using the work of a group of students when the assignment requires individual work;<br />

3. Looking <strong>at</strong> or <strong>at</strong>tempting to look <strong>at</strong> an exam or quiz before it is administered;<br />

4. Asking another student who has already taken an exam about the exam content;<br />

5. Using m<strong>at</strong>erials during an exam th<strong>at</strong> are not permitted;<br />

6. Allowing another student to complete an assignment, a quiz, or an exam for you;<br />

7. Intentionally impeding the academic work of others;<br />

8. Using any electronic device to transmit portions or questions or answers on an exam or quiz to other<br />

students;<br />

9. Using any electronic device to store inform<strong>at</strong>ion for an exam;<br />

10. Providing false <strong>at</strong>tendance d<strong>at</strong>a for another student;<br />

11. Knowingly furnishing false inform<strong>at</strong>ion to the University or its represent<strong>at</strong>ives;<br />

12. Falsifying results in labor<strong>at</strong>ory exercises;<br />

13. Assisting other students in any of the acts listed above.<br />

Plagiarism is a specific kind of academic dishonesty in which you take another’s ideas or words <strong>and</strong> claim them as<br />

your own. When you draw on someone else’s work, you must indic<strong>at</strong>e the source of th<strong>at</strong> m<strong>at</strong>erial, whether you<br />

are repe<strong>at</strong>ing another’s words, argument or thought. Even if you paraphrase another’s work <strong>and</strong> are not using the<br />

exact wording, you are still required to indic<strong>at</strong>e the source of the m<strong>at</strong>erial. This m<strong>at</strong>erial must be clearly<br />

identified with appropri<strong>at</strong>e cit<strong>at</strong>ions. If you do not do th<strong>at</strong>, you have plagiarized those m<strong>at</strong>erials. Any time you<br />

copy <strong>and</strong> paste any writing th<strong>at</strong> is not your own for an assignment, you must use quot<strong>at</strong>ion marks <strong>and</strong> give the<br />

source of th<strong>at</strong> m<strong>at</strong>erial. If you cut <strong>and</strong> paste without noting wh<strong>at</strong> you have done, you will be guilty of plagiarism.<br />

Even if the writing is your own, if it has been used for a previous assignment th<strong>at</strong> should be indic<strong>at</strong>ed.<br />

As per the MWSU policy, in BIO 251, a viol<strong>at</strong>ion of academic honesty or plagiarism will result in a zero grade on<br />

the assignment or exam. A second viol<strong>at</strong>ion of academic honesty or plagiarism may result in failing the course.<br />

Grade appeal procedure:<br />

Students are responsible for meeting the st<strong>and</strong>ards for academic performance established in each of the courses in<br />

which they are enrolled. The establishment of criteria for grades <strong>and</strong> the evalu<strong>at</strong>ion of academic performance are the<br />

responsibilities of the instructor deleg<strong>at</strong>ed by this University. The grade appeal procedure is available for the review of<br />

allegedly capricious grading or clerical error by the instructor <strong>and</strong> not for the purpose of evalu<strong>at</strong>ing the student’s<br />

academic performance in any particular course. The course grade appeal procedure is detailed on p26 of the MWSU<br />

Student H<strong>and</strong>book, available online <strong>at</strong> http://www.missouriwestern.edu/h<strong>and</strong>book/index.pdf .


BIO 251 4<br />

LECTURE SCHEDULE: (Tent<strong>at</strong>ive <strong>and</strong> subject to change)<br />

D<strong>at</strong>e Day Topic Textbook chapter<br />

8/30 M <strong>Course</strong> introduction & policies; Microbiology: Then <strong>and</strong> Now 1<br />

9/1 W<br />

9/3 F Review of organic molecules; Concepts <strong>and</strong> tools for studying<br />

microorganisms<br />

2, 3<br />

9/6 M LABOR DAY HOLIDAY – NO CLASS<br />

9/8 W<br />

9/10 F Prokaryotic cell structure <strong>and</strong> function 4<br />

9/13 M<br />

9/15 W Prokaryotic growth <strong>and</strong> nutrition 5<br />

9/17 F Prokaryotic genetics <strong>and</strong> gene transfer 8, 9<br />

9/20 M<br />

9/22 W Viruses: an<strong>at</strong>omy, replic<strong>at</strong>ion, <strong>and</strong> evolution 12<br />

9/24 F<br />

9/27 M Fungi & Protozoa 11<br />

9/29 W EXAM 1<br />

10/1 F Control of microbial growth: physical & chemical 7<br />

10/4 M<br />

10/6 W Control of microbial growth: chemotherapeutics 18<br />

10/8 F<br />

10/11 M Infection <strong>and</strong> disease 13<br />

10/13 W<br />

10/15 F<br />

10/18 M<br />

10/20 W<br />

10/22 F EXAM 2<br />

10/25 M Resistance <strong>and</strong> the immune system: inn<strong>at</strong>e immunity 14<br />

10/27 W<br />

10/29 F<br />

11/1 M Resistance <strong>and</strong> the immune system: acquired immunity 15<br />

11/3 W<br />

11/5 F<br />

11/8 M Immunity 16<br />

11/10 W Immune disorders 17<br />

11/12 F<br />

11/15 M EXAM 3<br />

11/17 W HIV/AIDS 17<br />

11/19 F<br />

11/23 M FALL BREAK – NO CLASS<br />

11/25 W FALL BREAK – NO CLASS<br />

11/27 F FALL BREAK – NO CLASS<br />

11/29 M Infectious diseases affecting the urinary <strong>and</strong> reproductive systems 24<br />

12/1 W<br />

12/3 F Infectious diseases affecting the skin <strong>and</strong> eyes 19<br />

12/6 M Infectious diseases affecting the respir<strong>at</strong>ory tract 20<br />

12/8 W Infectious diseases affecting the digestive system 21<br />

12/10 F Infectious diseases affecting the nervous system 22<br />

The final exam will be given during the <strong>schedule</strong>d final exam period, Wednesday, December 15 th from 2:00-3:50pm.


BIO 251 5<br />

LAB SCHEDULE: (Tent<strong>at</strong>ive <strong>and</strong> subject to change)<br />

D<strong>at</strong>e<br />

Aug 30/31<br />

Sept 1/2<br />

Sept 6/7<br />

Sept 8/9<br />

Sept 13/14<br />

Sept 15/16<br />

Sept 20/21<br />

Sept 22/23<br />

Sept 27/28<br />

Sept 29/30<br />

Oct 4/5<br />

Oct 6/7<br />

Oct 11/12<br />

Oct 13/14<br />

Oct 18/19<br />

Oct 20/21<br />

Oct 25/26<br />

Oct 27/28<br />

Nov 1/2<br />

Nov 3/4<br />

Nov 8/9<br />

Nov 10/11<br />

Nov 15/16<br />

Nov 17/18<br />

Nov 22/23<br />

Nov 24/25<br />

Nov 29/30<br />

Dec 1/2<br />

Dec 6/7<br />

Dec 8/9<br />

Lab topic <strong>and</strong> page reference in Symbiosis lab book<br />

Check in / p1 H<strong>and</strong> washing experiment / Culturing microbes from the environment (h<strong>and</strong>out)<br />

p3 Basic labor<strong>at</strong>ory techniques for isol<strong>at</strong>ion, cultiv<strong>at</strong>ion, <strong>and</strong> cultural characteriz<strong>at</strong>ion of<br />

microorganisms / p9 Culture transfer techniques / Techniques for isol<strong>at</strong>ion of pure cultures (p21 <strong>and</strong><br />

h<strong>and</strong>out)<br />

LABOR DAY HOLIDAY – No MONDAY or TUESDAY LABS<br />

p29 Microscopy / p31 Examin<strong>at</strong>ion of stained cell prepar<strong>at</strong>ions<br />

p39 Bacterial staining / p43 Prepar<strong>at</strong>ion of smears <strong>and</strong> simple stains<br />

p49 Gram stain<br />

p55 Acid-fast stain<br />

Gram stain unknown (10 pt activity)<br />

p61 Differential staining for visualiz<strong>at</strong>ion of bacterial cell structures<br />

p73 Physical <strong>and</strong> chemical agents for control of microbial growth / p75 Moist versus dry he<strong>at</strong> / p79<br />

Electromagnetic radi<strong>at</strong>ion<br />

p83 Chemical methods of control: disinfectants <strong>and</strong> antiseptics / p87 Chemotherapeutic agents<br />

CONVOCATION Thursday 10/7 – No WEDNESDAY or THURSDAY LABS<br />

p71 Fungi<br />

LAB EXAM 1 (h<strong>and</strong> in lab book for grading)<br />

p97 Selective <strong>and</strong> differential media /group project meeting time<br />

p103 Extracellular enzym<strong>at</strong>ic activities of microorganisms / p109 C<strong>at</strong>alase test / p113 Carbohydr<strong>at</strong>e<br />

ferment<strong>at</strong>ion / p119 Urease test<br />

p123 Utiliz<strong>at</strong>ion of amino acids / p129 Triple sugar-iron agar test / p133 IMViC test / p143<br />

Hydrogen sulfide test<br />

p147 Microbial flora of the mouth: susceptibility to dental caries /group project work time<br />

p151 Normal microbial flora of the thro<strong>at</strong> <strong>and</strong> skin / group project work time<br />

p151 Normal microbial flora of the thro<strong>at</strong> <strong>and</strong> skin continued / Probiotics (h<strong>and</strong>out)<br />

Probiotics continued / group project work time<br />

Group project present<strong>at</strong>ions<br />

Methods for detecting microbial infection (h<strong>and</strong>out)<br />

LAB EXAM 2 (h<strong>and</strong> in lab book for grading)<br />

FALL BREAK – NO CLASS<br />

FALL BREAK – NO CLASS<br />

Bacterial unknown identific<strong>at</strong>ion<br />

Bacterial unknown identific<strong>at</strong>ion<br />

Bacterial unknown identific<strong>at</strong>ion<br />

Bacterial unknown identific<strong>at</strong>ion DUE / group project quiz / check out<br />

NOTE: All students are required to wear some form of lab co<strong>at</strong> during lab exercises. Safety glasses or goggles are<br />

required for lab exercises which involve open flames <strong>and</strong>/or use of chemicals. Please make sure you have these supplies<br />

by the second lab class meeting. Goggles/safety glasses <strong>and</strong> disposable lab co<strong>at</strong>s are available from the Biology<br />

Administr<strong>at</strong>ive Assistant, Remington 218.

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