Prenatal screening and diagnosis of aneuploidy - isuog

Pre-Congress course:
Prenatal screening and
diagnosis of aneuploidy
23rd World Congress on Ultrasound
in Obstetrics and Gynecology
6 – 9 October 2013, Sydney, Australia
Incorporating the ASUM 43rd Annual Scientific Meeting
In partnership with:
Course directors:
Jon Hyett (Australia)
Jan Van Lith (The Netherlands)
Register
NOW
Date & location:
5 October 2013, Sydney, Australia
Fees:
Day delegate fee from $260
AUD
(includes lunch & refreshments)
CME available
Registration & contact:
Register online at
www.isuog.org/worldcongress2013
E: congress@isuog.org T: +44 (0)20 7471 9955

This course will review the status of ultrasound and screening for Down syndrome,
describe the advantages and limitations of novel molecular tools for prenatal
screening and diagnosis, define indications for these tools – based on current
ultrasound screening protocols and finally describe ways in which ultrasound
screening can adapt to the changing environment of molecular based testing.
08:30 Population based screening for Down syndrome in Denmark
An overview of the process and effectiveness of screening
08:50 Population based screening for Down syndrome in New Zealand
An overview of the process and effectiveness of screening
09:10 Resetting the standards of screening
Changing risk cut-offs to improve screening performance
09:30 Effective intervention for managing NT underperformers
10:00 Coffee
Molecular genetics: How the tests work
10:30 Examining DNA and RNA by arrays: techniques, technologies applications
and limitations
10:45 Sequencing: techniques, technologies, applications and limitations
11:00 The importance of bioinformatics: effects on clinical diagnosis and false
positive rates
Can’t see the wood for the trees: prenatal karyotyping by array CGH
11:15 Targeted molecular tools for prenatal diagnosis
11:35 Defining high risk groups that should be offered array CGH
11:55 Using array CGH for ‘routine’ fetal karyotyping
12:30 Lunch
Forget the trees, concentrate on the wood: non-invasive prenatal testing
13:30 Non-invasive testing: a summary of test efficiency
14:00 Non-invasive prenatal testing: clinical experience
14:20 Limited karyotyping: what we will miss
14:40 NIPT, first trimester ultrasound or both?
15:10 Coffee
Adjusting to the new clinical paradigm
15:40 Improving the screening efficiency of the first trimester scan
16:00 Screening for adverse pregnancy outcomes at 12 weeks
16:40 Diagnosing cardiac defects at 12 weeks: tips and tricks for the sonographer
17:00 Back to markers: non-invasive testing or arrays after a positive 20 week
anomaly scan?
17:20 Close