Gene Expression
Gene Expression
Gene Expression
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NimbleGen <strong>Gene</strong> <strong>Expression</strong> Prokaryotic Performance Data<br />
Extensive line of microbial multiplex catalog designs<br />
Prokaryotic <strong>Gene</strong> <strong>Expression</strong> Analysis<br />
Roche NimbleGen offers high density arrays for<br />
over 200 Class I, II, and III prokaryotic organisms<br />
in 385K and 4x72K array formats. Because each<br />
385K array contains up to 385,000 features, there is<br />
sufficient probe capacity to tailor an existing array<br />
design to address specific research questions.<br />
Consider including:<br />
Relevant plasmids<br />
Probes from intergenic regions<br />
Probes from multiple organisms<br />
Your own custom controls<br />
NimbleGen 4x72K microarrays for prokaryotic<br />
gene expression analysis enable you to conveniently<br />
and simultaneously hybridize four independent<br />
samples on each slide. These multiplex arrays offer<br />
a cost-effective approach to gene expression<br />
analysis. Similar to our 385K prokaryotic arrays,<br />
these arrays are available in a broad range of wholegenome<br />
catalog or custom designs tailored to your<br />
specific experimental goals.<br />
<br />
Figure 6: Sensitivity of NimbleGen E. coli <strong>Gene</strong><br />
<strong>Expression</strong> 4x72K Microarrays. The pairwise scatter plot of<br />
gene expression values (log 2<br />
) for wild type and mutant E. coli<br />
RNA correctly identifies 22 transcripts encoded by genes that<br />
are present in the wild type strain but deleted in the mutant<br />
strain (blue box). The number of genes (and as percent of<br />
total genes) differentially expressed at 2-, 4-, or 8-fold are<br />
indicated in the upper left.<br />
Performance<br />
Data<br />
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