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Primary FRCA OSCE-SOE exam January 2012 Coventry collection ...

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<strong>Primary</strong> <strong>FRCA</strong> <strong>OSCE</strong>-<strong>SOE</strong> <strong>exam</strong> <strong>January</strong> <strong>2012</strong><br />

Physics -<br />

1.press regulating valve - draw , explain<br />

2. Force , Newton , energy - in details .<br />

3. humidity - everything .<br />

<strong>SOE</strong> set 10<br />

Pharmacology:<br />

1) Pharmacokinetics: Absorption, Distribution (define Vd, give equations),<br />

Metabolism, Excretion. Draw a curve of plasma concentration of iv drug against time<br />

following bolus administration (one-compartment model). Write equation for this<br />

graph. How could you make analysis of this graph better? (semi-log). Please draw this<br />

new graph. What parameters can you derive from this graph. Tell me about<br />

bioavailability. What is time constant, half-life, relationship of one to the other.<br />

2) Anticholinesterases: Started off with 'what drug would you use to reverse<br />

neuromuscular blockade'. Then went on to details about each drug ie neostigmine,<br />

pyridostigmine, physotigmine, edrophonium, organophosphates & how they bind to<br />

the cholinesterase enz. Which used to treat myasthenia gravis. Sugammadex asked at<br />

the end.<br />

3) Receptors involved in vomiting: where centrally & peripherally. Different types of<br />

anti-emetics, and where they act, side effects. Why is metoclopramide not very<br />

effective. Why is chlorpromazine not used as anti-emetic.<br />

Physiology<br />

1) Cerebral blood flow. What maintains CBF. Monro-Kellie hypothesis. Volume of<br />

different compartments of skull (ie brain, CSF, blood). Different graphs showing<br />

effects of differing po2, pC02 on CBF. Mechanisms of autoregulation.<br />

2) Oxygen cascade. Photo of alveolus & pulmonary capillary - indicate the partial<br />

pressures of o2 & co2 at different sites. Hypoxic Pulmonary Vasoconstriction.<br />

3) Thyroid gland. Synthesis of thyroid hormones. Transport and MOA of T4/T3.<br />

Effects on body. Feedback mechanisms. Calcitonin & Ca metabolism.<br />

Physics<br />

1) Peripheral Nerve Stimulator. Where would you place PNS to monitor<br />

neuromuscular blockade? Why is ulnar crease better than facial nerve? (avoid direct<br />

muscle stimulation). TOF, DBS, Tetanic, PTC. Mechanism of fade. TOF ratio.<br />

2) Arterial Tourniquets: indications, components, contraindications, complications.<br />

3) Graphs: shown various graphs and asked to write the equations for each. Also<br />

asked to give clinical <strong>exam</strong>ples of each graph. (ie negative exponential, positive<br />

exponential, straight-line, rectangular hyperbolic)<br />

Clinical<br />

19yo male fell down stairs at nightclub at 2am. Brought into AE confused & agitated.<br />

Differential diagnoses, how manage, when would you intubate, etc. Straightforward.<br />

<strong>Coventry</strong> <strong>collection</strong>: Many thanks to the candidates from <strong>January</strong> <strong>2012</strong><br />

Course<br />

8

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