David Watkins - The Royal Marsden
David Watkins - The Royal Marsden
David Watkins - The Royal Marsden
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<strong>The</strong> <strong>Royal</strong> <strong>Marsden</strong><br />
Risk of second malignancies<br />
Relative risk<br />
Time at risk<br />
Sites at risk<br />
Chemotherapy<br />
alone<br />
2.0<br />
(95%CI 1.7-2.4)<br />
Peaks 5-9 years<br />
Nil > 15 years<br />
Lung<br />
NHL<br />
Leukeamia<br />
Combined<br />
modality<br />
3.9<br />
(95%CI 3.5-4.4)<br />
0-4 years to<br />
> 20 years<br />
In addition<br />
Colon<br />
NM Skin<br />
Breast<br />
Leukaemia risk and all-malignancies risk increased strongly with<br />
number of cycles of alkylating chemotherapy