CLS 426 Urine & Body Fluid Analysis - UNMC
CLS 426 Urine & Body Fluid Analysis - UNMC
CLS 426 Urine & Body Fluid Analysis - UNMC
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<strong>CLS</strong> <strong>426</strong> <strong>Urine</strong> & <strong>Body</strong><br />
<strong>Fluid</strong> <strong>Analysis</strong><br />
Renal Disease Part III<br />
Interstitial & Vascular Disease<br />
Interstitial Tissue Disease<br />
• Lower urinary tract infection<br />
– Cystitis (bladder)<br />
– Urethritis (urethra)<br />
• Acute pyelonephritis (upper UTI)<br />
• Yeast infection<br />
Ricki Otten MT(ASCP)SC<br />
uotten@unmc.edu<br />
• Any bacterial or fungal agent can cause a UTI<br />
Lower UTI<br />
• ~85% of lower UTI caused by<br />
gram-negative rods (fecal E.coli)<br />
• Urinalysis<br />
– Physical Color Clear<br />
– Chemical<br />
– Microscopic<br />
Lower UTI<br />
• Urinalysis<br />
– Physical yellow, hazy (cloudy, turbid)<br />
– Chemical <br />
– Microscopic<br />
Lower UTI<br />
• Urinalysis<br />
– Physical yellow, hazy (cloudy, turbid)<br />
– Chemical + protein (
Acute Pyelonephritis<br />
• Most common upper UTI<br />
• Two mechanisms causing infection<br />
– Bacterial moving from lower to upper urinary<br />
tract<br />
– Septicemia localizing in the kidneys<br />
• Incomplete voiding due to obstruction or<br />
dysfunction or anatomic abnormality<br />
• Catheterization, pregnancy, diabetes<br />
Acute Pyelonephritis<br />
• Urinalysis<br />
– Physical Color Clear<br />
– Chemical<br />
– Microscopic<br />
Acute Pyelonephritis<br />
• Urinalysis<br />
– Physical Yellow, hazy (cloudy, turbid)<br />
– Chemical <br />
– Microscopic<br />
Acute Pyelonephritis<br />
• Urinalysis<br />
– Physical Yellow, hazy (cloudy, turbid)<br />
– Chemical + protein (
Yeast Infection<br />
• Candida species (candida albicans)<br />
– Normal flora of GI tract and vagina<br />
– Normal bacterial flora keep yeast proliferation<br />
under control<br />
– Catheters provide mode of inoculation<br />
Yeast Infection<br />
• Urinalysis<br />
– Physical Color Clear<br />
– Chemical<br />
– Microscopic<br />
Yeast Infection<br />
• Urinalysis<br />
– Physical Yellow, hazy (cloudy)<br />
– Chemical <br />
– Microscopic<br />
Yeast Infection<br />
• Urinalysis<br />
– Physical Yellow, hazy (cloudy)<br />
– Chemical + WBC <br />
+ blood <br />
– Microscopic<br />
Yeast<br />
Mycelial elements<br />
RBC WBC<br />
Casts Why or why not<br />
Vascular Disease<br />
• Any disorder that affects the blood flow to<br />
the kidneys can cause renal disease<br />
– Cardiac disease (25% of cardiac output)<br />
– Atherosclerosis<br />
– Hypertension<br />
– Diabetes<br />
– Eclampsia<br />
–Etc<br />
<strong>CLS</strong> <strong>426</strong> <strong>Urine</strong> and <strong>Body</strong> <strong>Fluid</strong> <strong>Analysis</strong><br />
Student Laboratory – Urinalysis<br />
Renal Disease Part III: Interstitial & Vascular Disease Page 3
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