2011 Cancer Committee Members - Erlanger Health System

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Uterine Corpus (Endometrium) According to the American Cancer Society, an estimated 46,470 cases of the uterine corpus (body of the uterus) are expected to be diagnosed in 2011. These usually occur in the endometrium (lining of the uterus). Since 1992, incidence rates of endometrial cancer have been stable in white women, but increasing in African American women by 1.7% per year. An estimated 8,120 deaths are expected in 2011. Similar to incidence, death rates for cancer of the uterine corpus have been stable in white women, but increasing in African-American women by 0.8% per year since 1998. Signs and symptoms Abnormal uterine bleeding or spotting (especially in postmenopausal women) is a frequent early sign. Pain during urination, intercourse, or in the pelvic area is also a symptom. 25 Uterine Corpus Risk factors Obesity and greater abdominal fatness increase the risk of endometrial cancer, most likely by increasing the amount of estrogen in the body. Increased estrogen exposure is a strong risk factor for endometrial cancer. Other factors that increase estrogen exposure include menopausal estrogen therapy (without use of progestin), late menopause, never having children, and a history of polycystic ovary syndrome. (Estrogen plus progestin menopausal hormone therapy does not appear to increase risk.) Tamoxifen use increases risk slightly because it has estrogen-like effects on the uterus. Medical conditions that increase risk include Lynch syndrome, also known as hereditary nonpolyposis colon cancer (HNPCC), and diabetes. Pregnancy, use of oral contraceptives, and physical activity provide protection against endometrial cancer. Early detection There is no standard or routine screening test for endometrial cancer. Most endometrial cancer (69%) is diagnosed at an early stage because of postmenopausal bleeding. Women are encouraged to report any unexpected bleeding or spotting to their physicians. The American Cancer Society recommends that women with Lynch syndrome, or who are otherwise at high risk for endometrial cancer, should be offered annual screening with endometrial biopsy and/or transvaginal ultrasound beginning at 35 years of age. Treatment Uterine corpus cancers are usually treated with surgery, radiation, hormones, and/or chemotherapy, depending on the stage of disease. *Above information taken from the American Cancer Society Cancer Facts and Figures 2011
Introducing CyberKnife ® ... the world’s first and only robotic radiosurgery system. Only at Erlanger. CyberKnife offers a non-invasive alternative to surgery for the treatment of both cancerous and non-cancerous tumors anywhere in the body, including the head, spine, lung, prostate, breast, liver, and pancreas, in as few as 1–5 treatments. The CyberKnife Advantage Improved Treatment Delivery Unprecedented accuracy using real time lesion tracking Intelligent Robotics Unmatched Agility Radiosurgery Efficacy Non-Invasive Tumor Ablation Offering the world’s first lung optimized treatment that does not require invasive marker placement in most patients. Other treatment options offered at the Erlanger Cancer Center: Stereotactic Radiosurgery (SRS) Intensity Modulated Radiation Therapy (IMRT) Ultrasound guidance of IMRT 3-D Conformal Radiation Brachytherapy High Dose Rate/Low Dose Rate (HDR/LDR)
Page 1 and 2: Erlanger Health System 2011 Annual
Page 3 and 4: Adult Oncology The Erlanger Health
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2011 Cancer Committee Members - Erlanger Health System

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