Rationale for Thrombolysis
Rationale for Thrombolysis
Rationale for Thrombolysis
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Modified Rankin scores at 3 months<br />
0 1 2 3 4 5 Dead<br />
Pooled placebo<br />
0–3 h (n=465)<br />
14% 15% 11% 15% 20% 8% 17%<br />
Pooled alteplase<br />
0–3 h ( n=463)<br />
19% 23% 7% 14% 12% 7% 18%<br />
SITS-MOST<br />
(n=6,136)<br />
19% 20% 16% 15% 14% 5% 11%<br />
Modified Rankin scores at 3 months in SITS-MOST and randomised<br />
controlled trials <strong>for</strong> placebo and alteplase patients<br />
Wahlgren N et al Lancet 2007; 369: 275−282.