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ADHD and Autism Spectrum Disorders - Autismconsultingservices ...

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<strong>ADHD</strong> & <strong>Autism</strong><br />

The Overlapping Genetic Link <strong>and</strong> What Lies<br />

Underneath


Learning Objectives:<br />

• Present key medical research that powerfully<br />

demonstrates a genetic overlap between <strong>ADHD</strong>/<br />

<strong>Autism</strong> <strong>and</strong> implications<br />

• Provide a shift in perspective on adult <strong>ADHD</strong><br />

challenges <strong>and</strong> create a picture of what<br />

empowering from a place of strength looks like.<br />

• Introduce the "Attention Model" <strong>and</strong> demonstrate<br />

its effectiveness through the skill of "Attending".<br />

• Apply the use of attending for our clients to<br />

develop <strong>and</strong> implement sensory strategies that<br />

creates focus, motivation, <strong>and</strong> follow-through


More than 50% of children with <strong>ADHD</strong><br />

meet the diagnostic criteria for autism<br />

spectrum disorders.


More than 50% of children with <strong>ADHD</strong><br />

meet the diagnostic criteria for autism<br />

spectrum disorders.<br />

<br />

It is estimated that 30 to 80% of children<br />

with autism have <strong>ADHD</strong>


<strong>ADHD</strong>:<br />

Inattention<br />

Hyperactivity<br />

Impulsivity


<strong>Autism</strong>:<br />

Social interaction<br />

Communication<br />

Repetitiveness


Subtle behavioral differences...<br />

Which one is it


Hyperactive child experiencing anxiety due to sudden<br />

changes in his environment.<br />

VS.<br />

Hyperactive child needing to release energy


<strong>Autism</strong> <strong>and</strong> <strong>ADHD</strong> showing up in the<br />

same families <strong>and</strong> showing aggression<br />

<strong>and</strong> general disruptive behavior


Researchers<br />

started<br />

digging in<br />

<strong>and</strong> found<br />

clues !


"There is a lot more to discover about<br />

the genetics of both conditions."<br />

Philip Asherson, Prof. of Molecular Psychiatry, Kings College,<br />

London, Engl<strong>and</strong>


More than half of the genes in one condition also<br />

influenced the other condition


Individuals with <strong>ADHD</strong> score higher on<br />

tests for autism-like symptoms than do<br />

their siblings or "healthy" controls.


Individuals with <strong>ADHD</strong> score higher on<br />

tests for autism-like symptoms than do<br />

their siblings or "healthy" controls.<br />

Male siblings of children with <strong>ADHD</strong><br />

score higher on the tests than do<br />

children in the general population.


Researchers collected DNA<br />

<strong>and</strong> behavioral data...


Researchers collected DNA<br />

<strong>and</strong> behavioral data...<br />

248 children with <strong>ADHD</strong>


Researchers collected DNA<br />

<strong>and</strong> behavioral data...<br />

248 children with <strong>ADHD</strong><br />

349 children with autism


22 kids with <strong>ADHD</strong> had a copy number variation<br />

not found in "healthy" kids <strong>and</strong> five of those kids<br />

had copy number variations that also appeared in<br />

nine kids with autism.


22 kids with <strong>ADHD</strong> had a copy number variation<br />

not found in "healthy" kids <strong>and</strong> five of those kids<br />

had copy number variations that also appeared in<br />

nine kids with autism.<br />

A mutation in the gene ASTN2 found in the<br />

development of neurons reveals more...


"Clearly these are genes that affect the development of<br />

the brain. But why changes in these genes would be<br />

shaped into one disorder in one person <strong>and</strong> a different<br />

disorder in another person is going to be a question for<br />

a long time, I'm sure."<br />

Russell Schachar, Senior Scientist of Psychiatry at the Hospital<br />

for Sick Children, Toronto, Canada


What do we conclude<br />

• The studies indicate literally hundreds of genes at<br />

play in autism <strong>and</strong> a different combination could be<br />

at the root of each child's case.


What do we conclude<br />

• The studies indicate literally hundreds of genes at<br />

play in autism <strong>and</strong> a different combination could be<br />

at the root of each child's case.<br />

• Diagnostic labels limit our ability to<br />

underst<strong>and</strong> <strong>and</strong> intervene on behalf of<br />

<strong>ADHD</strong> <strong>and</strong> autistic individuals


What do we conclude<br />

• The studies indicate literally hundreds of genes at<br />

play in autism <strong>and</strong> a different combination could be<br />

at the root of each child's case.<br />

• Diagnostic labels limit our ability to<br />

underst<strong>and</strong> <strong>and</strong> intervene on behalf of<br />

<strong>ADHD</strong> <strong>and</strong> autistic individuals<br />

• Finding the genetic beacons <strong>and</strong> brain<br />

pathways they control will eventually help us<br />

target better treatments.


Beyond the labels:<br />

• New perspective on the challenges facing<br />

adults with <strong>ADHD</strong>


Beyond the labels:<br />

• New perspective on the challenges facing<br />

adults with <strong>ADHD</strong><br />

• Adult <strong>ADHD</strong> in a place of strength


Beyond the labels:<br />

• New perspective on the challenges facing<br />

adults with <strong>ADHD</strong><br />

• Adult <strong>ADHD</strong> in a place of strength<br />

• What's underneath the label


Beyond the labels:<br />

• New perspective on the challenges facing<br />

adults with <strong>ADHD</strong><br />

• Adult <strong>ADHD</strong> in a place of strength<br />

• What's underneath the label<br />

• Interventions


What does the general public conclude in<br />

their minds when they hear these three<br />

descriptive words<br />

Inattention<br />

Hyperactivity<br />

Impulsivity


<strong>ADHD</strong>:<br />

A challenge of attention


<strong>ADHD</strong>:<br />

A challenge of attention<br />

A challenge of interest


<strong>ADHD</strong>:<br />

A challenge of attention<br />

A challenge of interest<br />

<br />

A challenge of integrity


The "Attention Model"


"The intuitive mind is a sacred gift <strong>and</strong> the rational<br />

mind is a faithful servant. We have created a society<br />

that honors the servant <strong>and</strong> has forgotten the gift."<br />

Albert Einstein


Attending:<br />

Paying attention...<br />

Huh<br />

...to what is being<br />

paid attention to.


"I just want to hit the ball. "<br />

8-year-old boy


The skill of<br />

"attending"<br />

applied:<br />

Allow me to introduce<br />

you to Bob!


Inattentive <strong>and</strong> unaware<br />

Forgetful, Mind Drifting<br />

"Oh, I<br />

forgot!"<br />

Excessive attention to nonproductive<br />

activity with<br />

repetition


• How do we raise Bob's awareness so he can focus<br />

• How do we increase interest in other areas of Bob's<br />

life where responsibility is required<br />

• How do we create motivation necessary to help<br />

Bob repetitively follow through on his daily living<br />

tasks


Bob :<br />

The replacement behavior goal<br />

The replacement behavior objective


Bob :<br />

What lies underneath<br />

The replacement behavior procedure


Strategic uses of Bob's unique<br />

sensory profile


Internalizing the replacement behavior:<br />

Answering the question "Who"


Resources used:<br />

"<strong>Autism</strong>, <strong>ADHD</strong> share genetic similarities" http://www.foxnews.com/health/<br />

2011/08/11/autism-adhd-share-genetic-similarities/<br />

"<strong>ADHD</strong>, autism may sometimes share gene mutations" http://<br />

health.usnews.com/health-news/family-health/brain-<strong>and</strong>-behavior/articles/<br />

2011/08/10/adhd-autism-may-sometimes-share-gene-mutations<br />

"<strong>ADHD</strong> <strong>and</strong> autism: Is it in the genes" http://www.everydayhealth.com/addadhd/adhd-<strong>and</strong>-autism-is-it-in-the-genes.aspx<br />

"Researchers probed genetic overlap between <strong>ADHD</strong> <strong>and</strong> autism" http://<br />

sfari.org/news-<strong>and</strong>-opinion/news/2010/researchers-probe-genetic-overlapbetween-adhd-autism<br />

"Evaluating Dopamine Reward Pathway in <strong>ADHD</strong>: Clinical Implications" Nora<br />

Valkow, MD, www.jama.jamanetwork.com/article.aspxarticleid=184547


Resources used (continued):<br />

"<strong>Autism</strong> <strong>and</strong> <strong>ADHD</strong> in children: is there a genetic overlap" http://<br />

www.babble.com/kid/child-development/autism-adhd-causes-geneticbasis-2/<br />

"<strong>Autism</strong> <strong>and</strong> <strong>ADHD</strong> shared genetic similarities" http://<br />

www.myhealthnewsdaily.com/1570-autism-adhd-share-genetic-similarities.htm<br />

"ADD Coach Academy: Transforming the ADD perspective", Coaching<br />

school manual, www.ADDCA.com<br />

"So, Who Programmed U" Manual, Jeff Copper, MBA, Dig Coaching<br />

Practice, www.digcoaching.com<br />

"Coaching the World's Brains to Empower Human Global Gains", David<br />

Giwerc, MCC, www.ADDCA.com<br />

"Fidget to Focus Outwit your Boredom: Sensory Strategies For Living with<br />

ADD" Rotz, Ph.d & Wright, M.S., ACT, www.fidgettofocus.com

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