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although used sometimes, is too generic and non-in<strong>for</strong>mative. As far as I am concerned (i don't know<br />

the opinion of other reviewers) it can be skipped. The SSIM is a better choice since it is grounded on<br />

the human visual system. However, a table with SSIM results is not present. Please, add the table with<br />

SSIM and a discussion section on the results.<br />

Furthermore, although I do not request it (although it is advisable), the paper would benefit from a<br />

larger set of test images and a statistical test (ANOVA or paired t-test) between the SSIM results of the<br />

proposed method and the baseline methods.<br />

With regards to the MR images, which are a good choice (the context is specific), the authors ran into<br />

the problem of the lack of the baseline image (= image without the noise). Here, the best thing to do<br />

would be to have an expert (phisician) provide the scores <strong>for</strong> the image quality. Again, i do not request<br />

this, but it is a drawback in the evaluation and gives little credibility to the work presented. Since I've<br />

seen different ways in which the CNR and SNR have been implemented, the authors should provide<br />

more details on their implementation of the metrics.<br />

The final issue related to the evaluation is the results. Both in the synthetic and MR images the<br />

proposed method does not outper<strong>for</strong>m any of the baseline algorithms, according to the results. In some<br />

cases it is better in some cases not. The authors must provide a more thorough discussion on when their<br />

approach is better than the compared ones. Furthermore, they should remove bold and generic<br />

statements about the quality of their algorithm (e.g. "It is evident that the proposed algorithm achieves a<br />

better edge and structure preservation than other state-of-the-art methods.") and replace them with more<br />

objective observations.<br />

(2) PRESENTATION issues<br />

The introduction with related work is relatively well structured. The authors list a number of related<br />

techniques and their drawbacks. However, when they introduce their approach it is not clear how it<br />

differs from the related work, i.e. what is the contribution of the presented work. If the proposed work<br />

is just another implementation of image denoising with no clear advantages over the existing<br />

approaches, then it is not OK. Please state very clearly how your contribution differs from the others.<br />

When you state "... both the combined denoising strategy and adaptive dimensionality reduction<br />

approach of similar patch groups" it is not clear what the contribution is.<br />

In Sec. 2 the authors jump too quikly to the description of the algorithm's details. Please provide a<br />

subsection (2.1) with an overview of the procedure along with a figure showing various steps of the<br />

workflow.<br />

Another very important issue is the lack of domain. The authors simply state that the noise is a gaussian<br />

noise. This is too generic. Please specify which applications (acquisition devices, processing devices ...)<br />

add that kind of noise. Provide strong arguments <strong>for</strong> the choice of the noise model. Put your work in<br />

context.<br />

Last but not least, the manuscript would benefit from an improvement of english. Although the prose is

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