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A Case Report and Literature Review Anucha Thatrimontrichai ...

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เชื้อเมลิออยด์ในทารกแรกเกิด อนุชา ธาตรีมนตรีชัย<br />

Table 1 Demographic <strong>and</strong> clinical characteristics of 22 documented cases of neonatal melioidosis sorted by year of publication<br />

<strong>Case</strong><br />

Country,<br />

year<br />

Age<br />

at<br />

onset<br />

(days)<br />

PROM<br />

Mode of<br />

delivery<br />

GA<br />

(weeks)<br />

BW<br />

(g)<br />

Mode<br />

of<br />

transmission<br />

Clinical<br />

features<br />

NA,<br />

but<br />

chrioamnionitis<br />

Investigation<br />

Diagnosis<br />

Treatment <strong>and</strong><br />

duration of<br />

antibiotics<br />

therapy<br />

Outcome<br />

1<br />

2<br />

3<br />

4<br />

5<br />

Sex<br />

USA, M<br />

1971 16<br />

Thail<strong>and</strong>, M<br />

1988 10<br />

Thail<strong>and</strong>, F<br />

1988 10<br />

Thail<strong>and</strong>, F<br />

1988 10<br />

Thail<strong>and</strong>, M<br />

1988 10<br />

2<br />

(37 h)<br />

14<br />

14<br />

IAB<br />

IAB<br />

No<br />

No<br />

No<br />

Yes<br />

(1 week)<br />

Forceps<br />

extraction<br />

Forceps<br />

extraction<br />

C/S<br />

due to<br />

placental<br />

previa<br />

totalis<br />

SVD<br />

(criminal<br />

abortion<br />

5 days<br />

before<br />

delivery)<br />

SVD<br />

Term<br />

33<br />

32<br />

32<br />

Preterm<br />

2,977<br />

1,230<br />

1,370<br />

1,340<br />

1,330<br />

NA †<br />

Probably<br />

HCAI<br />

Probably<br />

HCAI<br />

NA<br />

NA<br />

Poor<br />

sucking,<br />

lethargy,<br />

fever,<br />

jaundice,<br />

grunting<br />

Asymptomatic<br />

Respiratory<br />

distress,<br />

apnea,<br />

lethargy<br />

Asymptomatic<br />

Severe<br />

respiratory<br />

distress<br />

NA<br />

WBC6,750<br />

(PMN40%,<br />

B<strong>and</strong>11%)<br />

WBC1,980<br />

(PMN70%,<br />

B<strong>and</strong>17%)<br />

NA<br />

NA<br />

-B. pseudomallei<br />

sepsis <strong>and</strong><br />

meningitis<br />

-Depressed right<br />

frontal skull<br />

fracture<br />

-Pneumonia<br />

-B. pseudomallei<br />

<strong>and</strong> Klebsiella<br />

sepsis<br />

-Twin B, sterile<br />

CSF<br />

-B. pseudomallei<br />

sepsis, sterile CSF<br />

- Omphalitis<br />

-B. pseudomallei<br />

sepsis<br />

-B. pseudomallei<br />

sepsis<br />

-Respiratory<br />

distress syndrome<br />

-Surgery at 3 h<br />

after birth<br />

-Polymyxin B<br />

(parenterally<br />

<strong>and</strong> intrathecally),<br />

9 h<br />

-Cefotaxime<br />

<strong>and</strong> gentamicin,<br />

14 d<br />

-Ceftazidime,<br />

20 d<br />

-Penicillin <strong>and</strong><br />

gentamicin,<br />

10 d<br />

-Penicillin <strong>and</strong><br />

gentamicin,<br />

20 h<br />

Died<br />

(119 h<br />

after<br />

birth)<br />

Recovered<br />

Recovered<br />

Recovered<br />

Died (20<br />

h after<br />

birth)<br />

238<br />

ส§¢ÅÒ¹¤ÃÔ¹·ร์àǪสÒà »‚·Õè 29 ©ºÑº·Õè 5 ก.ย.-ต.ค. 2554

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