Douglas Korver, Implications of Changing Immune Function ...

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Selection for Growth • Resource allocation theory (Rauw et al. 1998) – Selection against other traits • Eg. metabolic, reproductive Resource Reproduction Reproduction Growth Growth Immunity Immunity Metabolic Metabolic
Selection for Growth • Selection <strong>of</strong> broilers for performance: – reduced acquired immunity antibody production – reduced acquired immunity antibody production (Qureshi and Havenstein, 1994; Cheema et al., 2003) HOWEVER…. – effects depend on the response being measured • modern broilers – reduced systemic response to pro-inflammatory challenges – reduced pro-inflammatory cytokines (Leshchinsky et al., 2001, Humphrey and Klasing, 2004; Xie et al., 2000)
Page 1 and 2: Implications of Changing Immune Fun
Page 3 and 4: The Immune System • Two arms of t
Page 5 and 6: The Immune System • Immune system
Page 7 and 8: Immunology for Nutritionists • In
Page 9 and 10: Environment and Growth 100 90 80 70
Page 11 and 12: % OF NON-INJECTED CONTROL Inflammat
Page 13 and 14: Modern Poultry Production • Comme
Page 15 and 16: The Immune System • What do we kn
Page 17 and 18: • Example -- Zinc - Zinc deficien
Page 19: Selection for Growth • Growth rat
Page 23 and 24: Commercial “C” Random bred 1957
Page 25 and 26: Commercial “C” Random bred 1977
Page 27 and 28: T-cell Response to IL-1 Stimulation
Page 29 and 30: Implications • Genetic selection
Page 31 and 32: The Chick • First week of life be
Page 33 and 34: Innate Immune Development • Can w
Page 35 and 36: Implications • Early nutrition ca
Page 37 and 38: n-3 vs n-6 Fatty Acids Arachidonic
Page 39 and 40: 20-C PUFA Cyclooxygenase Lipoxygena
Page 41 and 42: Stimulation Index 3 Serum IL-1 Acti
Page 43 and 44: Nutritional Modulation of Immune Fu
Page 45 and 46: Lesion Score 2.5 2.0 ab Histopathol
Page 47 and 48: Implications • n-3 PUFA can “un
Page 49: Conclusions • Understand the poss

Douglas Korver, Implications of Changing Immune Function ...

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