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Original Contributions of Latin-Ameri- cans to Anesthesia

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and children in 1975 though they seldom<br />

receive recognition in pediatric regional<br />

anesthesia reviews. 64<br />

Since then this technique has been used<br />

in millions <strong>of</strong> patients.<br />

In 1989 Jorge Barrios-Alarcon et al 65 ,<br />

from São Paulo, Brazil proposed the alternative<br />

use <strong>of</strong> dextran 40 for the treatment<br />

<strong>of</strong> PDPH with a similar rate <strong>of</strong> success<br />

and without the potential hazards <strong>of</strong> the<br />

injection <strong>of</strong> au<strong>to</strong>logous blood in <strong>to</strong> the ES.<br />

Castaños et al 66 also showed that hemodilution<br />

and epidural anesthesia would reduce<br />

the blood viscosity and increased the PaO2<br />

<strong>of</strong> patients having hema<strong>to</strong>crit levels above<br />

70% in La Paz, Bolivia, at 14,000 feet high.<br />

Alber<strong>to</strong> Torrieri from Buenos Aires et<br />

Figure 14: Multiple paravertebral nerve block approached<br />

retrocostally <strong>to</strong> allow cholecystec<strong>to</strong>my and biliary surgery.<br />

al 67 described the first single-double lumen<br />

needle (Figure 15) used <strong>to</strong> provide Combined<br />

spinal-epidural anesthesia <strong>to</strong> patients<br />

undergoing major orthopedic procedures.<br />

Ricardo Plancarte et al 68 from Mexico City<br />

demonstrated in 1989, the feasibility and<br />

effectiveness <strong>of</strong> performing the superior<br />

hypogastric plexus block for the treatment<br />

<strong>of</strong> severe chronic pelvic pain. A year later,<br />

the same group 69 described the approach <strong>to</strong><br />

block the ganglion <strong>of</strong> Whar<strong>to</strong>n (impar) for<br />

the treatment <strong>of</strong> intractable perineal pain.<br />

Other related contributions have explained<br />

unilateral epidural blocks by the misplacement<br />

<strong>of</strong> catheters 70 and the application <strong>of</strong><br />

peridural anesthesia in Bernard-Horner<br />

syndrome. 71<br />

Other <strong>Contributions</strong><br />

Luis Agote 72 described in Buenos Aires<br />

the technique <strong>of</strong> clotting prevention by a<br />

precisely titrated dosification <strong>of</strong> Na citrate<br />

facilitating the development <strong>of</strong> blood banking<br />

making blood transfusions available<br />

<strong>to</strong> every one that needed them. On what<br />

appears <strong>to</strong> be the premier recommendation<br />

for moment <strong>to</strong> moment moni<strong>to</strong>ring <strong>of</strong><br />

patients under anesthesia, the picturesque<br />

and flamboyant Juan Marin from Bogotá<br />

Colombia, in 1934 insisted that the precordial<br />

stethoscope should be used <strong>to</strong> listen<br />

continuously <strong>to</strong> the heart and lung sounds<br />

<strong>of</strong> pediatric patients undergoing anesthesia<br />

so “cardiac arrhythmias and cardiac arrest<br />

can be identified as they happen.” 73<br />

Jose C. Delorme assembled the first<br />

anesthesia machine built in Argentina that<br />

included vaporizers for ether, chlor<strong>of</strong>orm<br />

and ethyl chloride and tanks for oxygen and<br />

CO2 as well as a soda lime absorber used for<br />

the first time in the Italian Hospital in Buenos<br />

Aires in late 1934. 74 Later on, Kentaro<br />

Takaoka 75 from São Paulo, Brazil designed<br />

the portable Takaoka ventila<strong>to</strong>r that could<br />

be held in one hand; it was used extensively<br />

as anesthesiologists went from<br />

clinic <strong>to</strong> clinic <strong>to</strong> give anesthetics,<br />

for resuscitation and<br />

even prolonged mechanical<br />

ventilation. The same author<br />

developed an universal ventila<strong>to</strong>r<br />

that could be used for all<br />

inhalation anesthetics available<br />

in 1965 76 and a breathing<br />

anesthetic circuit that could<br />

be used for children and<br />

adults in 1968 77 predating the<br />

Bain 78 circle by over a decade.<br />

The Takaoka family has expanded<br />

as manufacturer <strong>of</strong><br />

equipment from incuba<strong>to</strong>rs,<br />

<strong>to</strong> ventila<strong>to</strong>rs, <strong>to</strong> anesthetic<br />

machines and everything else<br />

in between providing reliable equipment,<br />

instruction and maintenance, at reasonable<br />

cost for nearly 50 years.<br />

In 1949, Aranes and Blusque Castellanos<br />

added intermittent boluses <strong>of</strong> thiopental and<br />

meperidine <strong>to</strong> an intravenous infusion <strong>of</strong><br />

procaine 79 creating another attempt <strong>to</strong> <strong>to</strong>tal<br />

intravenous anesthesia. This work was presented<br />

at the 1 st <strong>Latin</strong> <strong>Ameri</strong>can Congress<br />

Figure 15: Distal portion <strong>of</strong> the Torrieri-Aldrete double<br />

lumen needle for Combined Spinal-Epidural <strong>Anesthesia</strong><br />

(1984).<br />

BULLETIN OF ANESTHESIA HISTORY 9<br />

<strong>of</strong> Anesthesiology in Buenos Aires, at what<br />

turned out <strong>to</strong> be the first true international<br />

congress in Anesthesiology preceding the<br />

Paris International Congress held in 1951.<br />

Two novel ideas were proposed at that meeting<br />

a “consultation room” and a “recovery<br />

room.” Later on Wikinski et al 80 studied the<br />

pharmacokinetics and pharmacodynamics<br />

<strong>of</strong> procaine IV and related them <strong>to</strong> the levels<br />

<strong>of</strong> anesthesia obtained. This technique<br />

became very popular in Argentina and other<br />

South <strong>Ameri</strong>can countries where millions<br />

<strong>of</strong> anesthetics were administered with<br />

“Procaine a la Argentine,” until the 1980s<br />

when fluorinated hydrocarbon anesthetics<br />

were introduced. It is worth mentioning that<br />

only one case <strong>of</strong> malignant hyperthermia<br />

was reported during this period. R. Caldero-<br />

Barcia and his associates 81 in the Hospital de<br />

Clinicas in Montevideo studied the physiology<br />

<strong>of</strong> uterine contractions by cannulating<br />

the uterine cavity and vessels <strong>of</strong> mothers in<br />

labor. They also observed the effects <strong>of</strong> regional<br />

anesthesia and magnesium sulfate on<br />

uterine contractility as well as on maternal<br />

and neonatal vital signs (Figure 16).<br />

The Postanesthetic Recovery Score first<br />

proposed in 1970 82 , in its original form or<br />

in one <strong>of</strong> its modifications has become the<br />

standard <strong>of</strong> care in nearly all <strong>of</strong> the <strong>Ameri</strong>can<br />

continent and other countries in establishing<br />

the physical condition <strong>of</strong> patients<br />

recovering from anesthesia and surgery as<br />

well as their discharge eligibility.<br />

Preoccupation with the prevention <strong>of</strong> the<br />

undesirable effects from ketamine, as well<br />

as unconventional indications have motivated<br />

a number <strong>of</strong> investigations. Albin<br />

et al 83 prevented the psychogenic disturbances<br />

with tetrahy-droamiquidinic acid<br />

(THA), while Martinez Aguirre claimed <strong>to</strong><br />

reverse them with 4-aminopiridine 84 ; the<br />

same group 85 demonstrated that ketamine<br />

produced adequate analgesia and muscle<br />

relaxation when used with<br />

the technique <strong>of</strong> regional IV<br />

anesthesia and Jose Islas et<br />

al 86 demonstrated the central<br />

analgesic effects <strong>of</strong> ketamine<br />

when administered by the<br />

epidural route <strong>to</strong> patients in<br />

the pos<strong>to</strong>perative period.<br />

On a similar vein, A. Oswaldo<br />

Auad 87 , from Buenos<br />

Aires, showed in 1985 that<br />

epidural clonidine potentiated<br />

morphine analgesia in<br />

the treatment <strong>of</strong> patients with<br />

recalcitrant chronic pain.<br />

Del Castillo and Katz described<br />

the location and expanded<br />

the understanding <strong>of</strong><br />

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